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Positive New Data for Johnson & Johnson Single-Shot COVID-19 Vaccine on Activity Against Delta Variant and Long-lasting Durability of Response
NEW BRUNSWICK, N.J., July 1, 2021 – Johnson & Johnson (NYSE: JNJ) (the Company) today announced data that demonstrated its single-shot COVID-19 vaccine generated strong, persistent activity against the rapidly spreading Delta variant and other highly prevalent SARS-CoV-2 viral variants. In addition, the data showed that the durability of the immune response lasted through at least eight months, the length of time evaluated to date. The two preprint study summaries have been submitted today to bioRxiv. “Today’s newly announced studies reinforce the ability of the Johnson & Johnson COVID-19 vaccine to help prot...
Source: Johnson and Johnson - July 1, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

How the Delta Variant Affects Whether You Should Wear a Mask or Not
As infections involving the new Delta variant of the COVID-19 virus continue to increase around the world, including in the U.S., health experts are yet again revisiting advice about who should wear masks and when. On June 28, the Los Angeles County public health department advised all people, including those who are vaccinated, to wear masks in most indoor public settings, based on the fact that nearly half of the virus from cases in the county that were genetically sequenced now belong to the Delta variant. The variant, first identified in India, is far more contagious than previous strains of SARS-CoV-2, and could cause...
Source: TIME: Health - July 1, 2021 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

Call to action: Air pollution, asthma, and allergy in the exposome era
According to the World Health Organization, by 2050, approximately 50% of the world ’s population will have had asthma and/or allergy at least once in life.1 Increasing evidence suggests that air pollution is a primary risk factor that can help explain the increase in incidence of these diseases.2
Source: Journal of Allergy and Clinical Immunology - July 1, 2021 Category: Allergy & Immunology Authors: Isabella Annesi-Maesano, Cara Nichole Maesano, Benedetta Biagioni, Gennaro D ’Amato, Lorenzo Cecchi Tags: Paradigms and perspectives Source Type: research

The Delta Variant Could Soon Become the Dominant COVID-19 Strain. Here ’s What You Need to Know
The COVID-19 pandemic is increasingly becoming an arms race among the emerging variants of the virus, and at the moment, there’s no question which one is winning: the Delta variant—formally known as B.1.617.2—one of four strains to have emerged originally in India. It was just last month that the World Health Organization labeled Delta a “variant of concern”—joining with the Alpha strain, which emerged in the U.K.; the Beta strain, from South Africa; and the Gamma strain, first seen in Brazil. But Delta is fast becoming the most worrisome of the bunch. Health officials are sounding the a...
Source: TIME: Science - June 15, 2021 Category: Science Authors: Alejandro de la Garza and Jeffrey Kluger Tags: Uncategorized COVID-19 Source Type: news

Long-term exposure to low-level air pollution and incidence of asthma: the ELAPSE project
Conclusions Long-term exposure to air pollution, especially from fossil fuel combustion sources such as motorised traffic, was associated with adult-onset asthma, even at levels below the current limit values.
Source: European Respiratory Journal - June 4, 2021 Category: Respiratory Medicine Authors: Liu, S., Jorgensen, J. T., Ljungman, P., Pershagen, G., Bellander, T., Leander, K., Magnusson, P. K. E., Rizzuto, D., Hvidtfeldt, U. A., Raaschou-Nielsen, O., Wolf, K., Hoffmann, B., Brunekreef, B., Strak, M., Chen, J., Mehta, A., Atkinson, R. W., Bauweli Tags: Asthma and allergy Original Articles: Asthma Source Type: research

Johnson & Johnson Joins World Health Organization in Efforts to Prevent Spread of Ebola in West Africa
Discussions are ongoing with the U.S. Food and Drug Administration regarding the approval of the vaccine regimen in the U.S. WHO Prequalification is often a prerequisite for national registrations of new vaccines and medicines in developing countries. Johnson & Johnson now looks forward to collaborating with the WHO’s African Vaccine Regulatory Forum (AVAREF) to progress national registrations of the Company’s Ebola vaccine regimen. The Company’s Ebola vaccine regimen is designed to be used proactively to induce immunity against Ebola virus disease in adults and children. Johnson & Johnson’s Commitment to E...
Source: Johnson and Johnson - May 13, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

The evidence is in that asthma is not associated with severe coronavirus disease 2019
In December 2019, a novel respiratory illness caused by severe acute respiratory syndrome coronavirus 2 was first noted in Wuhan, People's Republic of China, and was subsequently named coronavirus disease 2019 (COVID-19). COVID-19 presents with pneumonia and a severe respiratory illness similar to severe acute respiratory syndrome, another zoonotic illness caused by a coronavirus. COVID-19 was reported to have initial mortality rates as high as 15%.1 In March 2020, the World Health Organization declared COVID-19 a global pandemic.
Source: Annals of Allergy, Asthma and Immunology - May 1, 2021 Category: Allergy & Immunology Authors: Dylan T. Timberlake, Mitchell H. Grayson Tags: Editorial Source Type: research

Johnson & Johnson Single-Shot COVID-19 Vaccine Phase 3 Data Published in New England Journal of Medicine
NEW BRUNSWICK, N.J., April 21, 2021 – Johnson & Johnson (the Company) today announced publication in the New England Journal of Medicine of primary data from the Phase 3 ENSEMBLE clinical trial for its single-dose COVID-19 vaccine, developed by the Janssen Pharmaceutical Companies of Johnson & Johnson (Janssen). The publication of the primary analysis follows the topline efficacy and safety data announced in January, showing the trial met all primary and key secondary endpoints, and found that the Johnson & Johnson single-dose COVID-19 vaccine prevented hospitalization and death across all study participants ...
Source: Johnson and Johnson - April 21, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Practical handling of allergic reactions to COVID-19 vaccines
ConclusionAllergy testing is not necessary for the vast majority of allergic patients prior to COVID-19 vaccination with currently licensed vaccines. In case of allergic/anaphylactic reactions after vaccination, allergy workup is recommended, as it is for a  small potential risk population prior to the first vaccination. Evaluation and approval of diagnostic tests should be done for this purpose.
Source: Allergo Journal International - April 19, 2021 Category: Allergy & Immunology Source Type: research

FDA Approves Xolair (omalizumab) Prefilled Syringe for Self-Injection Across All Indications
●  Xolair for self-injection offers healthcare providers and appropriate patients another administration option for more flexibility in managing their treatmentBasel, 13 April 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has approved the company ’s supplemental Biologics License Application for Xolair® (omalizumab) prefilled syringe for self-injection across all approved U.S. indications.1 Xolair is the only FDA-approved biologic designed to target and block immunoglobulin E (IgE) for the treatment of moderate to severe persistent allergic asthma, chronic...
Source: Roche Media News - April 13, 2021 Category: Pharmaceuticals Source Type: news

Johnson & Johnson Expands Phase 2a Clinical Trial of COVID-19 Vaccine Candidate to Include Adolescents
New Brunswick, NJ (April 2, 2021) – Johnson & Johnson (the Company) has begun vaccinating adolescent participants in the ongoing Phase 2a clinical trial for its COVID-19 vaccine candidate, developed by the Janssen Pharmaceutical Companies of Johnson & Johnson. “The COVID-19 pandemic has had a profound impact on adolescents, not just with the complications of the disease, but with their education, mental health, and wellbeing,” said Paul Stoffels, M.D., Vice Chairman of the Executive Committee and Chief Scientific Officer at Johnson & Johnson. “It is vital that we develop vaccines for everyone, everywher...
Source: Johnson and Johnson - April 2, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

COVID Fatigue in the Allergy Clinic
In January 2020 the world became aware of a novel virus circulating in Wuhan, China. By March 2020 SARS-CoV-2, had spread across the globe prompting a pandemic declaration by the World Health Organization and “shutdowns” of varying degrees in almost every facet of life.1 The healthcare industry was certainly not spared. Many in the specialty of Allergy& Immunology saw their practices adversely affected as patients were afraid to venture into clinical settings. Allergists were forced to modify their approach to patient care as they were unsure how to keep their patients and staff safe.
Source: Annals of Allergy, Asthma and Immunology - March 31, 2021 Category: Allergy & Immunology Authors: Joseph P. Forester, Sumana C. Reddy, J. Wesley Sublett, Marissa R. Shams, J. Allen Meadows Source Type: research

Coronavirus disease 2019 fatigue in the allergy clinic
In January 2020, the world became aware of a novel virus circulating in Wuhan, China. By March 2020, severe acute respiratory syndrome coronavirus 2 had spread across the globe prompting a pandemic declaration by the World Health Organization and shutdowns of varying degrees in almost every facet of life.1 The health care industry was certainly not spared. Many in the specialty of allergy and immunology saw their practices adversely affected because patients were afraid to venture into clinical settings.
Source: Annals of Allergy, Asthma and Immunology - March 31, 2021 Category: Allergy & Immunology Authors: Joseph P. Forester, Sumana C. Reddy, J. Wesley Sublett, Marissa R. Shams, J. Allen Meadows Tags: Perspective Source Type: research