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White House Wants Hospitals, Insurers to Provide Actual Costs of Care
Government officials say the objective is to encourage competition and reduce costs
Source: Pulmonary Medicine News - Doctors Lounge - November 19, 2019 Category: Respiratory Medicine Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nephrology, Neurology, Nursing, Oncology, Ophthalmology, Orthopedics, ENT, Source Type: news
Duke University could receive up to $400M to improve flu vaccine
Thanks to a historic grant package from the federal government, Duke University researchers are tasked with creating a long-lasting, non-seasonal flu shot.
Stemming from the same White House effort that's benefiting Triangle companies, Duke University has received $29.6 million from the National Institute of Allergy and Infectious Diseases (NIAID). The sizable research allotment Is part of a multi-contract award potentially worth up to $400 million o ver the next seven years – meaning it could…
Source: bizjournals.com Health Care:Biotechnology headlines - October 7, 2019 Category: Biotechnology Authors: Seth Thomas Gulledge Source Type: news
Skin Testing before Antibiotic Administration - Is there a Scientific basis?
Authors: Narayan P, Rupert E
Abstract
The practice of skin testing prior to administration of antibiotics in the absence of a history of allergy is non-existent in the western world. Reports on skin testing in the absence of known allergy are unheard of in the medical literature. The practice of giving a test dose prior to administration of the antibiotic is also practiced very sporadically and has no scientific basis. Despite this In India in most major institutions both in government and private hospitals , general practice set up and small and medium nursing homes, skin testing prior to administration of antibio...
Source: Journal of the Association of Physicians of India - September 30, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research
A ‘Cure’ for Ebola but Will it Stop the Outbreak if People Won’t Get Treatment?
Health workers inside a "CUBE" talk to an Ebola patient, while a nurse consults a chart outside. ALIMA Ebola Treatment Centre, Beni, Democratic Republic of the Congo. Two drugs have been found to successfully treat the Ebola virus. Aid agencies have welcomed the news saying it allows communities to access early treatment. Courtesy: World Health Organisation (WHO)By Issa Sikiti da SilvaCOTONOU, Benin, Aug 20 2019 (IPS) While people in the Democratic Republic of Congo (DRC) are slowly being made aware that scientists have discovered two drugs that are effective in treating Ebola, letting go of the fear and anxiety that has p...
Source: IPS Inter Press Service - Health - August 20, 2019 Category: International Medicine & Public Health Authors: Issa Sikiti da Silva Tags: Africa Development & Aid Editors' Choice Featured Health Human Rights Humanitarian Emergencies Population Poverty & SDGs Regional Categories TerraViva United Nations Democratic Republic of Congo (DRC) ebola Source Type: news
Use of Growth Factors and Other Cytokines for Treatment of Injuries During a Radiation Public Health Emergency.
This report reviews the information presented, and provides an overview of the discussions from a guided breakout session.
PMID: 31081742 [PubMed - as supplied by publisher]
Source: Radiation Research - May 12, 2019 Category: Physics Authors: DiCarlo AL, Horta ZP, Aldrich JT, Jakubowski AA, Skinner WK, Case CM Tags: Radiat Res Source Type: research
Use of Growth Factors and Cytokines to Treat Injuries Resulting from a Radiation Public Health Emergency.
Abstract
In response to concerns over possible radiological or nuclear incidents, the Radiation and Nuclear Countermeasures Program within the National Institute of Allergy and Infectious Diseases (NIAID) was tasked by the U.S. Department of Health and Human Services to support development of medical countermeasures (MCM) to treat the acute and delayed injuries that can result from radiation exposure. To date, the only three drugs approved by the U.S. Food and Drug Administration for treatment of acute radiation syndrome are growth factors targeting granulocyte (Neupogen® or Neulasta®) or granulocyte and macroph...
Source: Radiation Research - May 6, 2019 Category: Physics Authors: Horta ZP, Case CM, DiCarlo AL Tags: Radiat Res Source Type: research
Loss-of-Function in SMAD4 Might Not Be Critical for Human Natural Killer Cell Responsiveness to TGF- β
This study was carried out in accordance with approval of the Melbourne Health and Walter and Eliza Hall Institute of Medical Research's Human Research Ethics Committee (approval number: 2013.081). All subjects gave written informed consent for participation and publication.
Results and Discussion
TGF-β signaling in NK cells is associated with: phosphorylation in SMAD2 and 3, inhibition of IL-15-induced metabolism/proliferation, simultaneous downregulation of CD44, CD49e, and Eomes, and upregulation of CD16 and CD49a expression (7, 10). SMAD family member 4 (SMAD4) belongs to the SMAD family of transcript...
Source: Frontiers in Immunology - April 30, 2019 Category: Allergy & Immunology Source Type: research
P38 and JNK Mitogen-Activated Protein Kinases Interact With Chikungunya Virus Non-structural Protein-2 and Regulate TNF Induction During Viral Infection in Macrophages
This study has been funded by the Council of Scientific and Industrial Research (CSIR), New Delhi, India, vide grant no 37 (1542)/12/EMR-II and Department of Science and Technology (DST-SERB), New Delhi, India, vide grant no EMR/2016/000854. It was also supported by Institute of life sciences, Bhubaneswar, under Department of Biotechnology and National Institute of Science Education and Research (NISER), Bhubaneswar, under Department of Atomic Energy (DAE), Government of India.
Conflict of Interest Statement
The authors declare that the research was conducted in the absence of any commercial or financial relationships th...
Source: Frontiers in Immunology - April 11, 2019 Category: Allergy & Immunology Source Type: research
A Mysterious, Paralyzing Illness in Kids Is Worrying U.S. Health Officials: New Report
(NEW YORK) — One morning last fall, 4-year-old Joey Wilcox woke up with the left side of his face drooping.
It was the first sign of an unfolding nightmare.
Three days later, Joey was in a hospital intensive care unit, unable to move his arms or legs or sit up. Spinal taps and other tests failed to find a cause. Doctors worried he was about to lose the ability to breathe.
“It’s devastating,” said his father, Jeremy Wilcox, of Herndon, Virginia. “Your healthy child can catch a cold — and then become paralyzed.”
Joey, who survived but still suffers some of the effects, was one of 228...
Source: TIME: Health - April 2, 2019 Category: Consumer Health News Authors: MIKE STOBBE / AP Tags: Uncategorized illness medical onetime Source Type: news
Generating robust and informative nonclinical in vitro and in vivo bacterial infection model efficacy data to support translation to humans.
Abstract
In June 2017, The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, organized a workshop entitled "Pharmacokinetics-Pharmacodynamics (PK/PD) for Development of Therapeutics against Bacterial Pathogens". The aims were to discuss details of various PK/PD models and identify sound practices for deriving and utilizing PK/PD relationships to design optimal dosage regimens for patients. Workshop participants encompassed individuals from academia, industry and government, including the United States Food and Drug Administration. This and the accompanying review on ...
Source: Antimicrobial Agents and Chemotherapy - March 3, 2019 Category: Microbiology Authors: Bulitta JB, Hope W, Eakin AE, Guina T, Tam VH, Louie A, Drusano GL, Hoover JL Tags: Antimicrob Agents Chemother Source Type: research
Considerations for Dose Selection and Clinical Pharmacokinetics/Pharmacodynamics for the Development of Antibacterial Agents.
Abstract
In June 2017, The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, organized a workshop entitled "Pharmacokinetics-Pharmacodynamics (PK/PD) for Development of Therapeutics against Bacterial Pathogens" to discuss details and critical parameters of various PK/PD methods and identify approaches for linking human pharmacokinetic (PK) data and drug efficacy analyses. The workshop participants included individuals from academia, industry and government. This and the accompanying mini-review on nonclinical PK/PD summarize the workshop discussions and recommendatio...
Source: Antimicrobial Agents and Chemotherapy - March 3, 2019 Category: Microbiology Authors: Rizk ML, Bhavnani SM, Drusano G, Dane A, Eakin AE, Guina T, Jang SH, Tomayko JF, Wang J, Zhuang L, Lodise TP Tags: Antimicrob Agents Chemother Source Type: research
Studies of Deadly Flu Virus, Once Banned, Are Set to Resume
The government will allow research on bird flu that had been halted over safety concerns. But officials have not publicly announced the decision nor explained how it was made.
Source: NYT Health - March 1, 2019 Category: Consumer Health News Authors: DENISE GRADY Tags: Research Accidents and Safety Avian Influenza Erasmus Medical Center Health and Human Services Department University of Wisconsin National Institutes of Health National Institute of Allergy and Infectious Diseases Madison (Wis) Rotterdam Source Type: news
Retrospective Review of Insurance Coverage for Patch Testing
Insurance coverage and prior authorization (PA) requirements imposed by insurance companies have resulted in widespread barriers to care for both dermatology and allergy patients.1 –3 In a recent survey conducted by the American Academy of Dermatology (AAD), greater than two-thirds of 177 respondents from US-based AAD committee/task force members under the Council on Government Affairs, Health Policy, and Practice and Association of Dermatology Administrators/Managers member s reported that PA requirements negatively affect at least 1 patient daily.
Source: Annals of Allergy, Asthma and Immunology - February 22, 2019 Category: Allergy & Immunology Authors: Azam A. Qureshi, Olabola Awosika, Kamaria Nelson, Spencer Brodsky, Haijun Wang, Alison Ehrlich Source Type: research
Trump Wants to End HIV Within 10 Years. Here ’s What That Would Take, According to Experts
About 1.1 million Americans currently live with HIV, and approximately 40,000 are infected each year, according to federal data. But in his State of the Union address, President Donald Trump promised to “eliminate the HIV epidemic in the United States within 10 years” — a plan that hinges on a multi-agency push for better diagnosis, treatment and prevention in at-risk communities, health officials said Wednesday.
Trump introduced the plan during his annual address on Tuesday but offered few details. Health officials fleshed out the plan during a call with reporters on Wednesday.
The initiative will be ove...
Source: TIME: Health - February 6, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime HIV/AIDS onetime Source Type: news
