Trump Wants to End HIV Within 10 Years. Here ’s What That Would Take, According to Experts

About 1.1 million Americans currently live with HIV, and approximately 40,000 are infected each year, according to federal data. But in his State of the Union address, President Donald Trump promised to “eliminate the HIV epidemic in the United States within 10 years” — a plan that hinges on a multi-agency push for better diagnosis, treatment and prevention in at-risk communities, health officials said Wednesday. Trump introduced the plan during his annual address on Tuesday but offered few details. Health officials fleshed out the plan during a call with reporters on Wednesday. The initiative will be overseen by the Department of Health and Human Services (HHS) and will bring together the Centers for Disease Control and Prevention (CDC), the National Institute of Allergy and Infectious Diseases (NIAID), the Health Resources and Services Administration and the Indian Health Service. They will target 48 U.S. counties where HIV transmission is high, focusing on at-risk populations including transgender individuals, men who have sex with men and people of color. Efforts will focus on early diagnosis and treatment for people who are infected; access to proactive measures, such as the preventative drug PrEp, in vulnerable populations; and outbreak response, said Dr. Brett Giroir, Assistant Secretary for Health at HHS, on the call. The CDC and the National Institutes of Health’s (NIH) 19 Centers for AIDS Research will work with local health authorities to a...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime HIV/AIDS onetime Source Type: news

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Publication date: April 2020Source: Phytochemistry Letters, Volume 36Author(s): Fahd M. Abdelkarem, Ezz-Eldin K. Desoky, Alaa M. Nafady, Ahmed E. Allam, Aldoushy Mahdy, Maki Nagata, Tomofumi Miyamoto, Kuniyoshi ShimizuAbstractFurther chemical study of the crude extract of the soft coral Heteroxenia fuscescens (Fam., Xeniidea), led to isolation of two new sterols, Heterofuscesterols A (1) and B (2), a sterol isolated for the first time from natural sources, 3β,5α,6β-trihydroxyandrosta-17-one (3), along with one new hydroperoxy sesquiterpene, Heterofusceterpene A (4), and one known ceramide (5). Their structu...
Source: Phytochemistry Letters - Category: Chemistry Source Type: research
Publication date: Available online 21 February 2020Source: Chemical Engineering JournalAuthor(s): Meitong Ou, Chao Pan, Yongkang Yu, Xuan Wang, Yun Zhou, Hanjie Zhang, Qinzhen Cheng, Meiying Wu, Xiaoyuan Ji, Lin MeiAbstractExcessive reactive oxygen species (ROS), as effective cancer therapeutic agents, can promote tumor apoptosis. However, the clinical applications of ROS-mediated cancer therapies still have many limitations, such as self-defects of traditional photosensitizer, adverse tumor microenvironment (TME), and insufficient ROS production. Here, two-dimensional and highly oxidized ilmenite nanosheets (HOIL NSs, for...
Source: Chemical Engineering Journal - Category: Chemistry Source Type: research
Publication date: Available online 21 February 2020Source: Chemical Engineering JournalAuthor(s): Yang Zhang, Yanjun Xu, Di Sun, Zheying Meng, Weiwei Ying, Wei Gao, Rui Hou, Yuanyi Zheng, Xiaojun Cai, Bing Hu, Xianfang LinAbstractAs a promising treatment modality with spatial and temporal control, alternating magnetic field (AMF) triggered magnetic hyperthermal therapy (MHT) shows broad and promising applications to overcome the drawbacks of traditional focal therapies in combating cancer. However, the MHT efficacy is still not satisfactory with the presence of heat shock proteins (HSPs). In addition, sustained tumor hypox...
Source: Chemical Engineering Journal - Category: Chemistry Source Type: research
Chem. Commun., 2020, Accepted Manuscript DOI: 10.1039/D0CC00416B, CommunicationXinwei Tian, Zhao Li, Ning Ding, Jiahang Zhang We have developed a novel near-infrared ratiometric fluorescent theranostic nanoprobe. Reaction with glutathione, it would release a near-infrared fluorophore and chemotherapy drug. Notably, this nanoprobe can selectively kill cancer HeLa,... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - Category: Chemistry Authors: Source Type: research
Publication date: Available online 21 February 2020Source: MethodsXAuthor(s): Bogdan C. Donose, Ashwin Vijayan Premavally, Marie-Laure Pype, Katrin DoedererABSTRACTMonitoring the loss of integrity in reverse osmosis (RO) membranes is crucial for protection of public health as small imperfections can result in catastrophic pathogen outbreaks. However, understanding the phenomena accompanying the loss of integrity in RO membranes relies on properly characterizing and interpreting performance data. Reproducing chemical and mechanical damage in model membranes that mimic the conditions of real-time operation is difficult. Mech...
Source: MethodsX - Category: Science Source Type: research
This article presents her outstanding character and most important lines of research. The focus of her studies covered alkylative and oxidative damage to DNA bases, in particular mutagenic and carcinogenic properties of purines with an open imidazole ring and 8-oxo-7,8-dihydroguanine (8-oxoGua). They also included analysis of mutagenic properties and pathways for the repair of DNA adducts of lipid peroxidation (LPO) products arising in large quantities during inflammation. Professor Tudek did all of this in the hope of deciphering the mechanisms of DNA damage removal, in particular by the base excision repair (BER) pathway...
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - Category: Genetics & Stem Cells Source Type: research
ConclusionsBlood Metallothionein- 2A relative expression and oxidant status may have a prognostic value in breast cancer patients.
Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research
ConclusionThe results of the meta-analysis were found to be associated with PCOS condition. These genetic predisposition and pre prediction can interpret the chance of getting PCOS condition.
Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research
Researchers look to messenger RNA encased in nanoparticles, DNA plasmids, molecular clamps, and other approaches as they rush to design a vaccine against the new coronavirus.
Source: The Scientist - Category: Science Tags: News & Opinion Source Type: news
This study aims to address how the 2008 Wenchuan Earthquake influenced knowledge generation and diffusion compared to the research stemming from the 1989 Loma Prieta Earthquake in the United States and the 1995 Hanshin Awaji Earthquake in Japan, for the three countries are exposed to high seismic risk. The findings show that (1) regarding research quantity, the influence of the Wenchuan Earthquake on disaster-related knowledge generation is just beginning compared with the gradual decreases in research on the other earthquakes; (2) regarding disciplinary development, the proportion of studies relating to the Wenchuan Earth...
Source: Safety Science - Category: Occupational Health Source Type: research
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