P38 and JNK Mitogen-Activated Protein Kinases Interact With Chikungunya Virus Non-structural Protein-2 and Regulate TNF Induction During Viral Infection in Macrophages

This study has been funded by the Council of Scientific and Industrial Research (CSIR), New Delhi, India, vide grant no 37 (1542)/12/EMR-II and Department of Science and Technology (DST-SERB), New Delhi, India, vide grant no EMR/2016/000854. It was also supported by Institute of life sciences, Bhubaneswar, under Department of Biotechnology and National Institute of Science Education and Research (NISER), Bhubaneswar, under Department of Atomic Energy (DAE), Government of India. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Acknowledgments We are thankful to Dr. MM. Parida, DRDE, Gwalior, India for kindly providing DRDE-06 virus strain and Vero cell line. We wish to acknowledge the University Grant Commission (UGC), New Delhi, India for the fellowship to TKN during this study. Supplementary Material The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fimmu.2019.00786/full#supplementary-material References 1. Lumsden WH. An epidemic of virus disease in Southern Province, Tanganyika Territory, in 1952-53. II. General description and epidemiology. Trans R Soc Trop Med Hyg. (1955) 49:33–57. doi: 10.1016/0035-9203(55)90081-X PubMed Abstract | CrossRef Full Text | Google Scholar 2. Mason PJ, Haddow AJ. An epidemic of virus disease in Southern P...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research