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Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research
Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research
Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research
Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research
Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research
Staphylococcus aureus Enterotoxin B Is a Cofactor of Food Allergy beyond a Superantigen
J Immunol. 2023 Sep 13:ji2200549. doi: 10.4049/jimmunol.2200549. Online ahead of print.ABSTRACTStaphylococcus aureus enterotoxin B (SEB), one of the most common bacterial toxins in food contamination, has been poorly understood in relationship to food allergy outcomes. To investigate whether the ingestion of enterotoxins in food allergens could affect the development of food allergy, OVA-sensitized female BALB/c mice were challenged with OVA added with different doses of SEB or LPS. Allergic symptoms, such as diarrhea rate and hypothermia, could be aggravated in mice challenged with OVA and a low dose of SEB. The increased...
Source: Journal of Immunology - September 13, 2023 Category: Allergy & Immunology Authors: Jin Yuan Ping Tong Zhongliang Wang Xiaoqian Xu Xiaoli Zhao Xuanyi Meng Yong Wu Xin Li Jinyan Gao Hongbing Chen Source Type: research
Gut microbiome is associated with asthma and race in children with food allergy.
Source: Journal of Allergy and Clinical Immunology - September 13, 2023 Category: Allergy & Immunology Authors: Mahboobeh Mahdavinia, John P. Fyolek, Jialing Jiang, Neil Thivalapill, Lucy A. Bilaver, Christopher Warren, Susan Fox, Sai R. Nimmagadda, Pamela J. Newmark, Hemant Sharma, Amal Assa ’ad, Patrick C. Seed, Ruchi S. Gupta Source Type: research
Outcomes and factors associated with tolerance in infants with non-IgE-mediated cow's milk allergy with gastrointestinal manifestations
CONCLUSIONS: In infants with non-IgE-mediated CMPA with gastrointestinal manifestations, the use of cow's milk-based formula, a history of other food allergies, and hematochezia and diarrhea upon initial presentation were associated factors for the later achievement of tolerance.PMID:37696495 | DOI:10.1016/j.jped.2023.08.003
Source: Jornal de Pediatria - September 11, 2023 Category: Pediatrics Authors: Pr íscila da Silva Pereira Vasconcelos Ana Laura Mendes Becker Andrade Natascha Silva Sandy Juliana Corr êa Campos Barreto Gabriela Souza Gomez Adriana Gut Lopes Riccetto Elizete Aparecida Lomazi Maria Ângela Bellomo-Brandão Source Type: research
Risk factors predisposing children to food allergies
CONCLUSION: The most important aspect of this study was that it separately identified prenatal, neonatal, and postnatal risk factors for IgE- and non-IgE-mediated food allergies.PMID:37695233 | DOI:10.15586/aei.v51i5.937
Source: Allergologia et Immunopathologia - September 11, 2023 Category: Allergy & Immunology Authors: Ecem Firtin Is ılay Turan Deniz Ozceker Betul Buyuktiryaki Gonca Hancioglu Selami Ulas Sezin Naiboglu Ci ğdem Aydogmus Recep Sancak Mehmet Halil Celiksoy Source Type: research
Does the severity of atopic dermatitis change with allergic sensitization? Is it real or a myth?
CONCLUSION: While guidelines recommend investigating food allergies in moderate to severe AD, this study found no significant difference in the relationship between AD severity and the presence of FA. However, inhalant allergen sensitivity was linked to increased AD severity. Therefore, a comprehensive patient history should include an evaluation of food allergies in children with AD, regardless of disease severity. Elimination and provocation tests related to suspected food items should be performed, and allergenic foods should be removed from the diet if they are found to contribute to the allergy.PMID:37695232 | DOI:10.15586/aei.v51i5.921
Source: Allergologia et Immunopathologia - September 11, 2023 Category: Allergy & Immunology Authors: Serdar Al Suna Asilsoy Özge Atay Özge Kangallı Nevin Uzuner Source Type: research
Quality of life in children with food allergies, psychiatric symptoms, and caregiving burden of their mothers
CONCLUSION: In order to develop a multidisciplinary approach for children with food allergies, we conceived as appropriate to inform their families about the difficulties of caregiving and psychosocial disorders that could develop over time. They also must be informed to take preventive measures as well as the medical aspects of their children's disease.PMID:37695230 | DOI:10.15586/aei.v51i5.860
Source: Allergologia et Immunopathologia - September 11, 2023 Category: Allergy & Immunology Authors: N ülüfer Kılıç Şuheda Kaya G ülay Taşçı Filiz Özsoy Mehmet K ılıç Source Type: research
Risk factors predisposing children to food allergies
CONCLUSION: The most important aspect of this study was that it separately identified prenatal, neonatal, and postnatal risk factors for IgE- and non-IgE-mediated food allergies.PMID:37695233 | DOI:10.15586/aei.v51i5.937
Source: Allergologia et Immunopathologia - September 11, 2023 Category: Allergy & Immunology Authors: Ecem Firtin Is ılay Turan Deniz Ozceker Betul Buyuktiryaki Gonca Hancioglu Selami Ulas Sezin Naiboglu Ci ğdem Aydogmus Recep Sancak Mehmet Halil Celiksoy Source Type: research
Does the severity of atopic dermatitis change with allergic sensitization? Is it real or a myth?
CONCLUSION: While guidelines recommend investigating food allergies in moderate to severe AD, this study found no significant difference in the relationship between AD severity and the presence of FA. However, inhalant allergen sensitivity was linked to increased AD severity. Therefore, a comprehensive patient history should include an evaluation of food allergies in children with AD, regardless of disease severity. Elimination and provocation tests related to suspected food items should be performed, and allergenic foods should be removed from the diet if they are found to contribute to the allergy.PMID:37695232 | DOI:10.15586/aei.v51i5.921
Source: Allergologia et Immunopathologia - September 11, 2023 Category: Allergy & Immunology Authors: Serdar Al Suna Asilsoy Özge Atay Özge Kangallı Nevin Uzuner Source Type: research
Quality of life in children with food allergies, psychiatric symptoms, and caregiving burden of their mothers
CONCLUSION: In order to develop a multidisciplinary approach for children with food allergies, we conceived as appropriate to inform their families about the difficulties of caregiving and psychosocial disorders that could develop over time. They also must be informed to take preventive measures as well as the medical aspects of their children's disease.PMID:37695230 | DOI:10.15586/aei.v51i5.860
Source: Allergologia et Immunopathologia - September 11, 2023 Category: Allergy & Immunology Authors: N ülüfer Kılıç Şuheda Kaya G ülay Taşçı Filiz Özsoy Mehmet K ılıç Source Type: research
