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Total 380 results found since Jan 2013.

Current state of occupational latex allergy
Purpose of review During the 1980s, natural rubber latex (NRL) emerged as a major cause of occupational allergy and asthma, especially in healthcare workers using powdered NRL gloves. Increased recognition of NRL allergies and transfer of research findings into prevention strategies resulted into an almost elimination of this health problem. Here, the current knowledge on allergens, their use in diagnostics, prevalence data of occupational NRL allergy and the status of prevention strategy are summarized. Recent findings While the current studies conducted in high-income countries show that prevention measures have red...
Source: Current Opinion in Allergy and Clinical Immunology - February 28, 2020 Category: Allergy & Immunology Tags: OCCUPATIONAL DISEASE: Edited by Susan M. Tarlo and Piero Maestrelli Source Type: research

Evaluation of Eravacycline: A Novel Fluorocycline
Eravacycline (ERV), formerly known as TP ‐434, is a novel tetracycline (TET) antibiotic that exhibits in vitro activity against various gram‐positive, gram‐negative aerobic and anaerobic pathogens, including those exhibiting TET‐specific acquired resistance mechanisms. Similar to other TETs, it inhibits protein synthesis through bi nding to the 30S ribosomal subunit. Eravacycline was approved by the United States Food and Drug Administration (FDA) in August 2018 for the treatment of complicated intraabdominal infections (cIAIs) in adults following the Investigating Gram‐Negative Infections Treated with Eravacycli...
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - February 24, 2020 Category: Drugs & Pharmacology Authors: Sara Alosaimy, Jacinda C. Abdul ‐Mutakabbir, Razie Kebriaei, Sarah C. J. Jorgensen, Michael J. Rybak Tags: Review Of Therapeutics Source Type: research

FDA: 7 Sunscreen Chemicals Enter Bloodstream After Use, But Don ’ t Abandon Sun Protection
(CNN) — After a single application, a total of seven chemicals commonly found in sunscreens can be absorbed into the bloodstream at levels that exceed safety thresholds, according to studies by the Center for Drug Evaluation and Research, an arm of the US Food and Drug Administration. “What is most alarming about these findings is that chemicals are absorbing into the body in significant amounts and the ingredients have not been fully tested for safety,” said David Andrews, a senior scientist for the Environmental Working Group, or EWG, a consumer organization which advocates for sunscreen safety. “...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 21, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Sunscreen Source Type: news

Evaluation of Eravacycline: a Novel Flourocycline
AbstractEravacycline (ERV), formerly known as TP ‐434, is a novel tetracycline (TET) antibiotic that exhibitsin vitro activity against various gram ‐positive, gram‐negative aerobic and anaerobic pathogens, including those exhibiting TET‐specific acquired resistance mechanisms. Similar to other TETs, it inhibits protein synthesis through binding to the 30S ribosomal subunit. Eravacycline was approved by the United States Food and Drug Admi nistration (FDA) in August 2018 for the treatment of complicated intraabdominal infections (cIAIs) in adults following the Investigating Gram‐Negative Infections Treated with Er...
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - January 14, 2020 Category: Drugs & Pharmacology Authors: Sara Alosaimy, Jacinda C. Abdul ‐Mutakabbir, Razie Kebriaei, Sarah CJ Jorgensen, Michael J. Rybak Tags: REVIEW OF THERAPEUTICS Source Type: research

Prevalence and Characteristics of Shellfish Allergy in the Pediatric Population of the United States
ConclusionThe epidemiology of SA in the US pediatric population shows crustacean allergy is more common than mollusk allergy. A disparity in SA children and epinephrine auto-injector carriage exists. Results from this study will lead to increased awareness of the need for detailed histories, specific diagnostic tests, and rescue epinephrine for anaphylaxis in US children with SA.
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 7, 2020 Category: Allergy & Immunology Source Type: research

Recent Surveys on Food Allergy Prevalence
Substantial numbers of children and adults report having immunoglobulin E–mediated food allergies. However, generating accurate food allergy prevalence data is difficult. Self-reported data can overestimate prevalence when compared with prevalence estimates established by more rigorous methods. As of 2004, in the United States, the Food Allergen Labeling and Consumer Protection Act mandated that the label should declare the source of the food if the product contains that food or a protein-containing ingredient from that food (not all proteins in a major food allergen cause allergic reactions) in the manner described by t...
Source: Nutrition Today - January 1, 2020 Category: Nutrition Tags: Nutrition and the Lifecycle Source Type: research

Depression and anxiety in children with epilepsy and other chronic health conditions: National estimates of prevalence and risk factors
ConclusionsOne in four U.S. children with epilepsy has depression and/or anxiety. Therefore, physicians should consider the various factors that are related to depression and anxiety in children with epilepsy so that at-risk children can be screened and managed appropriately.
Source: Epilepsy and Behavior - December 21, 2019 Category: Neurology Source Type: research

Depression and anxiety in children with epilepsy and other chronic health conditions: National estimates of prevalence and risk factors.
CONCLUSIONS: One in four U.S. children with epilepsy has depression and/or anxiety. Therefore, physicians should consider the various factors that are related to depression and anxiety in children with epilepsy so that at-risk children can be screened and managed appropriately. PMID: 31870808 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - December 19, 2019 Category: Neurology Authors: LaGrant B, Marquis BO, Berg AT, Grinspan ZM Tags: Epilepsy Behav Source Type: research

The ingredient co-occurrence network of packaged foods distributed in the United States
Publication date: Available online 14 December 2019Source: Journal of Food Composition and AnalysisAuthor(s): Kathryn M CooperAbstractThis work presents a novel, comprehensive ingredient co-occurrence network of foods in the United States from the Open Food Database. This network, which contains over 69,000 ingredients and 2 million ingredient co-occurrence relationships, provides a glimpse into the current use of common ingredients for food production and distribution in the United States. Understanding food intake behaviors from this data-driven perspective opens up new avenues for precision health and wellness, for exam...
Source: Journal of Food Composition and Analysis - December 16, 2019 Category: Food Science Source Type: research

Camp Leadership Perspectives on Food Allergy–Related Anaphylaxis Events and Training for Camp Staff: A National Survey of Summer Camps
ConclusionsAppropriate policies to manage food anaphylaxis events and anaphylaxis management training were missing in a substantial proportion of camps. Camp-tailored food allergy training is needed given the number of camps reporting food allergy reactions requiring epinephrine.
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 13, 2019 Category: Allergy & Immunology Source Type: research

Camp Leadership Perspectives on Food Allergy Related Anaphylaxis Events and Training for Camp Staff: A National Survey of Summer Camps
ConclusionPresence of appropriate policies to manage food anaphylaxis events and anaphylaxis management training were missing in a substantial proportion of camps. Camp-tailored food allergy training is needed given the number of camps reporting food allergy reactions requiring epinephrine.
Source: The Journal of Allergy and Clinical Immunology: In Practice - November 24, 2019 Category: Allergy & Immunology Source Type: research

The American Registry for Migraine Research: Research Methods and Baseline Data for an Initial Patient Cohort.
CONCLUSIONS: ARMR is a source of real-world patient data, biospecimens, and brain neuroimaging data that provides comprehensive insight into patients with migraine and other headache types being seen in headache specialty clinics in the United States. ARMR data will allow for longitudinal and advanced analytics that are expected to lead to a better characterization of patient heterogeneity, healthcare resource utilization, identification of endophenotypes, factors that predict treatment outcomes and clinical course, and ultimately advance the field toward precision headache medicine. PMID: 31755111 [PubMed - as supplied by publisher]
Source: Headache - November 21, 2019 Category: Neurology Authors: Schwedt TJ, Digre K, Tepper SJ, Spare NM, Ailani J, Birlea M, Burish M, Mechtler L, Gottschalk C, Quinn AM, McGillicuddy L, Bance L, Dumkrieger G, Chong CD, Dodick DW Tags: Headache Source Type: research

An injection could someday keep peanut allergies at bay for up to six weeks, study says
More than 3 million people in the United States are allergic to peanuts and tree nuts. But experimental new research suggests adults might someday be able to take an antibody to keep symptoms at bay for up to six weeks -- at least in small doses.
Source: CNN.com - Health - November 16, 2019 Category: Consumer Health News Source Type: news

Evolution of Immune Responses in Food Immunotherapy
Food allergies are a growing public health concern affecting approximately 8% of children and 10% of adults in the United States. Several immunotherapy approaches are under active investigation, including oral immunotherapy, epicutaneous immunotherapy, and sublingual immunotherapy. Each of these approaches uses a similar strategy of administering small, increasing amounts of allergen to the allergic subject. Immunologic studies have described changes in the T-cell compartment, serum and salivary immunoglobulin profile, and mast cell and basophil degranulation status in response to allergens. This review highlights the immu...
Source: Immunology and Allergy Clinics of North America - November 5, 2019 Category: Allergy & Immunology Authors: Johanna M. Smeekens, Michael D. Kulis Source Type: research