• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

2017 ’ s Year In Health News: Medical Breakthroughs, Opioid Crisis And More
CBS Local — There’s been plenty of progress in the medical world this year, and as a result we now know that more Americans than ever have high blood pressure, but also that coffee everyday is actually good for you. Here’s a look back at the year in health. Opioid Crisis The opioid crisis has dominated much of the health news cycle. President Trump declared the opioid crisis a national emergency earlier this year. Drug overdoses are now the leading cause of death for people under 50 in the United States. New Guidelines for High Blood Pressure The American Heart Association revised its guidelines for high ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - December 20, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News best of 2017 Samantha Lazarus Bennet Source Type: news

Don ’t encourage vaginal seeding, healthcare professionals advised
Increasingly popular practice may be doing more harm than good, say doctors Related items fromOnMedica Babies should eat peanuts early on Hepatitis B vaccine to be added to childhood immunisation schedule Special infant milk formulas not protective against allergies Breastfeeding could cut children ’s leukaemia risk Experts question safety of ‘vaginal seeding’
Source: OnMedica Latest News - August 25, 2017 Category: UK Health Source Type: news

A cost analysis of individualized asparaginase treatment in pediatric acute lymphoblastic leukemia
ConclusionsTDM of asparaginase is cost saving if calculated with the absolute asparaginase dose and will be if the waste is minimalized by preparing multiple doses out of one vial.
Source: Pediatric Blood and Cancer - August 2, 2017 Category: Cancer & Oncology Authors: Robin Q.H. Kloos, Carin A. Uyl ‐de Groot, Raphaële R.L. Litsenburg, Gertjan J.L. Kaspers, Rob Pieters, Inge M. der Sluis Tags: RESEARCH ARTICLE Source Type: research

New cancer drug can prevent reactions to common airborne allergens
(Northwestern University) A cancer drug for patients with certain types of leukemia and lymphoma can also prevent reactions to some of the most common airborne allergies, according to a recent Northwestern Medicine study. The promising data from this pilot study could have greater implications for adults with food allergies.
Source: EurekAlert! - Medicine and Health - May 22, 2017 Category: International Medicine & Public Health Source Type: news

Inhibitory effects of 2-oxo-2H-chromen-4-yl 4-methylbenzenesulfonate on allergic inflammatory responses in rat basophilic leukemia cells.
In this study, we investigated the effects of coumarin derivatives on mast cell degranulation. The effect of coumarin derivatives on degranulation in rat basophilic leukemia (RBL)-2H3 cells was determined by a β-hexosaminidase assay and histamine assay. A coumarin derivative 1 (C1), 2-oxo-2H-chromen-4-yl 4-methylbenzenesulfonate, inhibited degranulation in a dose-dependent manner and demonstrated maximum therapeutic effect when used at 25μM. Additionally, these compounds inhibited the phosphorylation of the extracellular signal-regulated kinase (ERK) pathway. Taken together, these results indicate that 2-oxo-2H-chromen-4...
Source: International Immunopharmacology - May 17, 2017 Category: Allergy & Immunology Authors: Yoo G, Lee K, Lee DC Tags: Int Immunopharmacol Source Type: research

Abstract PR03: Association of environmental risk factors, family history, and polygenic risk scores with chronic lymphocytic leukemia
Conclusions: We found evidence of independent effects among the genetic and non-genetic factors with risk of CLL. Among these factors, the PRS had the largest effect size. Although we did not observe any statistical interactions, larger sample sizes are warranted to fully evaluate these effects on risk of CLL. We are currently increasing our sample size through collaboration with other research groups. Final results will be presented in the meeting.This abstract is also being presented as Poster A06.Citation Format: Geffen Kleinstern, Dennis Robinson, Tim G. Call, Mark Liebow, Silvia de Sanjosé, Yolanda Benavente, J...
Source: Cancer Epidemiology Biomarkers and Prevention - April 30, 2017 Category: Cancer & Oncology Authors: Kleinstern, G., Robinson, D., Call, T. G., Liebow, M., Sanjose, S. d., Benavente, Y., Cerhan, J. R., Slager, S. L. Tags: Improving Cancer Risk Prediction for Prevention and Early Detection: Oral Presentations - Proffered Abstracts Source Type: research

Allergic‐like reactions to asparaginase: Atypical allergies without asparaginase inactivation
ConclusionsIn conclusion, allergic‐like reactions occur relatively late after the start of infusion and without antibodies. Despite these clinical differences, allergic‐like reactions can only be distinguished from real allergies by continually measuring asparaginase activity levels. If clinically tolerated, formulations should not be switched in case of allergic‐like reactions. Moreover, failure to recognize these reactions may lead to a less favorable prognosis if asparaginase therapy is terminated unnecessarily.
Source: Pediatric Blood and Cancer - July 4, 2016 Category: Cancer & Oncology Authors: Robin Q. H. Kloos, Rob Pieters, Gabriele Escherich, Inge M. der Sluis Tags: Research Article Source Type: research

Allergic ‐like reactions to asparaginase: Atypical allergies without asparaginase inactivation
ConclusionsIn conclusion, allergic‐like reactions occur relatively late after the start of infusion and without antibodies. Despite these clinical differences, allergic‐like reactions can only be distinguished from real allergies by continually measuring asparaginase activity levels. If clinically tolerated, formulations should not be switched in case of allergic‐like reactions. Moreover, failure to recognize these reactions may lead to a less favorable prognosis if asparaginase therapy is terminated unnecessarily.
Source: Pediatric Blood and Cancer - July 3, 2016 Category: Cancer & Oncology Authors: Robin Q. H. Kloos, Rob Pieters, Gabriele Escherich, Inge M. der Sluis Tags: Research Article Source Type: research

Glyphosate Chemophobia Grips Sonoma County: Sprayers Don Hazmat Suits, Respirators After Switch to 'Safer' Organic Weed Killers
If you've followed the often acrimonious debate over GMOs in foods, you've probably seen pictures of farmers walking through corn and soy fields bedecked in hazardous material suits and respirators. Why do they wear protective gear? According to anti-GMO activists, they are protecting themselves from glyphosate, a chemical often paired with GMOs that they claim is a cancer-causing herbicide. These people wearing hazmat suits are actually Greenpeace activists ripping up genetically engineered plants in the Philippines in 2011. That's ironic in a tragic way as the plants being uprooted are engineered with the natural soil-...
Source: Science - The Huffington Post - June 2, 2016 Category: Science Source Type: news

Association of atopic diseases and parvovirus B19 with acute lymphoblastic leukemia in childhood and adolescence in the northeast of Brazil
Conclusions These results suggest that atopic diseases and elevated total IgE levels are associated with a potential protective effect on the development of ALL. Previous infection with parvovirus B19 contributed to ALL susceptibility.
Source: International Journal of Clinical Oncology - May 24, 2016 Category: Cancer & Oncology Source Type: research

Nanoallergens: A multivalent platform for studying and evaluating potency of allergen epitopes in cellular degranulation
In this study, we propose a new allergy model system for studying potential allergen epitopes using nanoallergens, liposomes modified to effectively display IgE binding epitopes/haptens. By utilizing the covalently conjugated lipid tails on two hapten molecules (dinitrophenol and dansyl), hapten molecules were successfully incorporated into liposomes with high precision to form nanoallergens. Nanoallergens, with precisely controlled high-particle valency, can trigger degranulation with much greater sensitivity than commonly used bovine serum albumin conjugates. In rat basophil leukemia cell experiments, nanoallergens with ...
Source: Experimental Biology and Medicine - May 12, 2016 Category: Research Authors: Deak, P. E., Vrabel, M. R., Pizzuti, V. J., Kiziltepe, T., Bilgicer, B. Tags: Original Research Source Type: research

Diagnosis and management of mastocytosis: an emerging challenge in applied hematology.
Authors: Valent P Abstract Mastocytosis is a unique and rare neoplasm defined by abnormal expansion and accumulation of clonal mast cells (MCs) in one or multiple organ systems. Most adult patients are diagnosed to have systemic mastocytosis (SM). Based on histological findings and disease-related organ damage, SM is classified into indolent SM (ISM), smoldering SM (SSM), SM with an associated hematologic non-MC-lineage disease (SM-AHNMD), aggressive SM (ASM), and MC leukemia (MCL). The clinical picture, course, and prognosis vary profoundly among these patients. Nonetheless, independent of the category of SM, neop...
Source: Hematology ASH Education Program - December 10, 2015 Category: Hematology Tags: Hematology Am Soc Hematol Educ Program Source Type: research

A Scalable Framework to Detect Personal Health Mentions on Twitter
Conclusions: It is possible to automatically detect personal health status mentions on Twitter in a scalable manner. These mentions correspond to the health issues of the Twitter users themselves, but also other individuals. Though this study did not investigate the veracity of such statements, we anticipate such information may be useful in supplementing traditional health-related sources for research purposes.
Source: Journal of Medical Internet Research - June 5, 2015 Category: Journals (General) Authors: Zhijun YinDaniel FabbriS Trent RosenbloomBradley Malin Source Type: research

Cesarean Section and Chronic Immune Disorders
This study analyzed the potential association of delivery by cesarean delivery with immune disorders to investigate the potential influence cesarean deliveries could have on development of such conditions. Data from registries in Denmark were used to identify children born between 1977 and 2012. Data were collected on mode of delivery as well as other variables, and the association with several immune diseases was analyzed. The data set included 2 million children over that 35-year period. Nine diseases and 8 confounders were analyzed. The effects of cesarean versus vaginal birth were investigated, and all data were analyz...
Source: Obstetrical and Gynecological Survey - May 1, 2015 Category: OBGYN Tags: Obstetrics: Newborn Medicine Source Type: research

Allergies and Risk of NHL in the Agricultural Health Study
Conclusions: Both the reduced risk of NHL among those with allergy symptoms and specific farm exposures in adulthood, and the increased risk among those who grew up on a farm suggest that the host immune response to agricultural allergens may influence NHL development. Impact: This prospective study is, to our knowledge, the first to investigate the relationship between allergy symptoms and NHL risk in farmers; confirmation of these findings in other farming populations is warranted. Cancer Epidemiol Biomarkers Prev; 24(3); 587–94. ©2015 AACR.
Source: Cancer Epidemiology Biomarkers and Prevention - March 5, 2015 Category: Cancer & Oncology Authors: Hofmann, J. N., Hoppin, J. A., Lynch, C. F., Poole, J. A., Purdue, M. P., Blair, A., Alavanja, M. C., Beane Freeman, L. E. Tags: Research Articles Source Type: research

Pages: 1  2  3  4