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Total 71 results found since Jan 2013.
520 A retrospective cohort study of patch testing in oral lichen planus and subsequent diagnosis of oral squamous cell carcinoma
Oral lichen planus (OLP) is a recalcitrant, relapsing autoimmune condition that poses a significant treatment challenge. Allergies to dental metals, fragrances, and additives have been documented in the setting of OLP. Likewise, oral squamous cell carcinoma (OSCC) has been reported to evolve in lesions of OLP. We hypothesized that the chronic inflammation of allergy-driven OLP may increase the odds of developing OSCC. Our primary objective was to compare the odds of OSCC between patch test negative and positive patients.
Source: Journal of Investigative Dermatology - April 17, 2023 Category: Dermatology Authors: V.N. Sahni, Z. Hopkins, J. Rhoads, J. Clarke, C. Hansen, D. Powell, R. deShazo, J. Zone, C. Hull Source Type: research
Cell-penetrating albumin enhances the sublingual delivery of antigens through macropinocytosis
Int J Biol Macromol. 2022 Sep 17:S0141-8130(22)02063-3. doi: 10.1016/j.ijbiomac.2022.09.132. Online ahead of print.ABSTRACTInnovations in oral immunotherapy have greatly advanced the therapeutic control of allergies. However, these therapeutic effects suffer from the fact that the amount of antigen delivered to antigen-presenting cells is limited given the formulations that are currently available. We recently designed a cell-penetrating albumin and found that this modified albumin enters cells via the induction of macropinocytosis. Herein, we report on a novel system for delivering antigens based on cell-penetrating album...
Source: International Journal of Biological Macromolecules - September 20, 2022 Category: Biochemistry Authors: Hitoshi Maeda Shota Ichimizu Hiroshi Watanabe Keisuke Hamasaki Mayuko Chikamatsu Ryota Murata Nao Yumoto Takahiro Seki Hiroshi Katsuki Masaki Otagiri Toru Maruyama Source Type: research
Pulmonary mucoepidermoid carcinoma in the Chinese population: A clinical characteristic and prognostic analysis
ConclusionThe clinical, radiographical and pathological features of pulmonary mucoepidermoid carcinoma were systemically analysed and summarized, and the degree of differentiation and lymph node metastasis, as well as prognostic factors in addition to clinical stage, were confirmed.
Source: Frontiers in Oncology - August 24, 2022 Category: Cancer & Oncology Source Type: research
Loco-regional treatment of hepatocellular carcinoma: Role of contrast-enhanced ultrasonography
World J Hepatol. 2022 May 27;14(5):911-922. doi: 10.4254/wjh.v14.i5.911. Epub 2022 Apr 7.ABSTRACTHepatocellular carcinoma (HCC) is one of the few cancers for which locoregional treatments (LRTs) are included in international guidelines and are considered as a valid alternative to conventional surgery. According to Barcelona Clinic Liver Cancer classification, percutaneous treatments such as percutaneous ethanol injection, radiofrequency ablation and microwave ablation are the therapy of choice among curative treatments in patients categorized as very early and early stage, while transcatheter arterial chemoembolization is ...
Source: World Journal of Hepatology - June 20, 2022 Category: Gastroenterology Authors: Agostino Inzerillo Maria Franca Meloni Adele Taibbi Tommaso Vincenzo Bartolotta Source Type: research
