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Total 14524 results found since Jan 2013.
Causative Microorganisms Isolated from Patients with Intra-Abdominal Infections and Their Drug Resistance Profiles: An 11-Year (2011-2021) Single-Center Retrospective Study
CONCLUSION: The distribution and antimicrobial susceptibility of the causative microorganisms from patients with IAIs were altered between 2011 and 2021. This finding is valuable for the implementation of evidence-based antimicrobial therapy and provides guidance for the control of hospital infections.PMID:37711085 | DOI:10.3967/bes2023.072
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Rui Ding Rui Rui Ma Ya Li Liu Ying Zhao Li Na Guo Hong Tao Dou Hong Li Sun Wen Jing Liu Li Zhang Yao Wang Ding Ding Li Qiao Lian Yi Ying Chun Xu Source Type: research
Effect of Probiotic Supplementation on the Gut Microbiota Composition of Infants Delivered by Cesarean Section: An Exploratory, Randomized, Open-label, Parallel-controlled Trial
CONCLUSIONS: Our results showed that probiotics supplemented immediately after CS enriched the gut microbiota composition and altered the pattern of early gut colonization.TRIAL REGISTRATION: registration number NCT05086458.PMID:37712964 | DOI:10.1007/s00284-023-03444-4
Source: Current Microbiology - September 15, 2023 Category: Microbiology Authors: Yujiao Gong Hui Zhong Jing Wang Xianggeng Wang Linsheng Huang Yutong Zou HuanLong Qin Rong Yang Source Type: research
In vitro and in vivo evaluation of two combined β-lactamase inhibitors against carbapenem-resistant Acinetobacter baumannii
The objective of this study was to evaluate the in vitro and in vivo efficacy of clavulanic acid (C/A) in combination with tazobactam against clinical strains of carbapenem-resistantAcinetobacter baumannii. The MIC of 24 clinical strains ofA. baumannii was determined, and a checkerboard assay and time-kill curve analysis were performed in selected strains to determine the synergy between C/A and tazobactam. The efficacy of C/A in monotherapy and in combination with tazobactam was evaluated in vitro in cell culture experiments and in a murine peritoneal sepsis model. The C/A and C/A plus tazobactam MIC50 were 128 and<1 m...
Source: European Journal of Clinical Microbiology and Infectious Diseases - September 15, 2023 Category: Microbiology Source Type: research
Viruses, Vol. 15, Pages 1934: Prevalence and Impact on Mortality of Colonization and Super-Infection by Carbapenem-Resistant Gram-Negative Organisms in COVID-19 Hospitalized Patients
Conclusions: Although KPC-producing Klebsiella pneumoniae and/or carbapenem-resistant Acinetobacter baumannii rectal carriage, and/or bloodstream infection/pneumonia were diagnosed in a remarkable percentage of COVID-19 patients, their impact on in-hospital mortality was not significant. Further studies are needed to assess the burden of antimicrobial resistance as a legacy of COVID-19 in order to identify future prevention opportunities.
Source: Viruses - September 15, 2023 Category: Virology Authors: Roberto Casale Gabriele Bianco Paulo Bastos Sara Comini Silvia Corcione Matteo Boattini Rossana Cavallo Francesco Giuseppe De Rosa Cristina Costa Tags: Article Source Type: research
Assessment of biofilm, enzyme production and antibiotic susceptibility of bacteria from milk pre- and post-pasteurization pipelines in Algeria
Int J Food Microbiol. 2023 Sep 9;407:110389. doi: 10.1016/j.ijfoodmicro.2023.110389. Online ahead of print.ABSTRACTBacterial biofilm is a major concern of dairy industry due to its association with milk contamination and its derived products. Algerian pasteurized milk shelf-life does not exceed one day, which may reflect the high level of contamination of this product and presence of extracellular enzymes such as lipases and proteases. This work aimed to investigate the microbial biodiversity in milk-processing surfaces of a dairy plant in Algeria. Therefore, stainless steel cylinders were placed in piping system of the da...
Source: International Journal of Food Microbiology - September 14, 2023 Category: Food Science Authors: Nassima Didouh Medjahdi Khadidja Carla Campos Benedita Sampaio-Maia Moussa Boudjemaa Boumediene Ricardo Araujo Source Type: research
Pertussis-like Syndrome Caused by Acinetobacter pittii ST119
Source: Indian Journal of Pediatrics - September 13, 2023 Category: Pediatrics Source Type: research
Microbiome data analysis via machine learning models: Exploring vital players to optimize kitchen waste composting system
This study aims to employ machine learning models to explore key microbial genera and to optimize composting systems. After introducing a novel microbiome preprocessing approach, Stacking models were constructed (R2 is about 0.8). The SHAP method (SHapley Additive exPlanations) identified Bacillus, Acinetobacter, Thermobacillus, Pseudomonas, Psychrobacter, and Thermobifida as prominent microbial genera (Shapley values ranging from 3.84 to 1.24). Additionally, microbial agents were prepared to target the identified key genera, and experiments demonstrated that the composting quality score was 76.06 for the treatment and 70....
Source: Bioresource Technology - September 13, 2023 Category: Biotechnology Authors: Shang Ding Liyan Jiang Jiyuan Hu Wuji Huang Liping Lou Source Type: research
Evidence supportive of a bacterial component in the etiology for Alzheimer ’s disease and for a temporal-spatial development of a pathogenic microbiome in the brain
ConclusionsThe AD-related pathogenicity of the brain microbiome seems to be based on a complex polymicrobial dynamic. The time ordering revealed a rise and fall of the abundance of C. acnes with pathogenicity occurring for an off-peak abundance level in association with at least one other bacterium from a set of genera that included Methylobacterium, Bacillus, Caulobacter, Delftia, and Variovorax. C. acnes may also be involved with outcompeting the Comamonas species, which were strongly associated with non-demented brain microbiota, whose early destruction could be the first stage of disease. Our results are also consisten...
Source: Frontiers in cellular and infection microbiology - September 13, 2023 Category: Microbiology Source Type: research
Nitrogen removal characteristics of heterotrophic nitrification-aerobic denitrification bacterium Acinetobacter ZQ-A1 and community characteristics analysis of its application in pig farm wastewater
Environ Sci Pollut Res Int. 2023 Sep 12. doi: 10.1007/s11356-023-29556-9. Online ahead of print.ABSTRACTA heterotrophic nitrifying aerobic denitrifying (HN-AD) strain ZQ-A1 with excellent denitrification performance, identified as Acinetobacter, was isolated from simultaneous nitrification and denitrification (SND) craft. ZQ-A1 was capable of removing NH4+, NO2-, and NO3-; the 21-hour removal rates were 84.84%, 87.13%, and 92.63%. ZQ-A1 has the ability to treat mixed nitrogen sources. In addition, ZQ-A1 can be well applied to actual sewage. According to the analysis of microbial community characteristics, the relative abun...
Source: Environmental Science and Pollution Research International - September 12, 2023 Category: Environmental Health Authors: Ze Cao Feng Huang Ruiyu Zhang Xiaoya Zhao Yan Wang Yinbao Wu Xindi Liao Yaoyu Feng Jingyun Ma Tian Lan Source Type: research
Treatment of Central Nervous System Infection Caused by Multidrug-Resistant Acinetobacter baumannii with Intravenous and Intraventricular Colistin Sulfate: A Case Report and Literature Review
Source: Infection and Drug Resistance - September 11, 2023 Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research
Excess mortality and long-term disability from healthcare-associated carbapenem-resistant < i > Acinetobacter baumannii < /i > infections: A nationwide population-based matched cohort study
by Chiu-Hsia Su, Li-Jung Chien, Chi-Tai Fang, Shan-Chwen Chang
BackgroundCarbapenem resistance is perceived as a clinical challenge in the management of debilitated and immunocompromised patients who eventually will die from underlying diseases. We aimed to examine whether carbapenem resistance per se, rather than the underlying diseases, negatively affect outcomes, by comparing the excess mortality and morbidity from healthcare-associated infections (HAIs) caused by carbapenem-resistantAcinetobacter baumannii (CRAB) and carbapenem-susceptibleA.baumannii (CSAB). MethodsThis was a nationwide retrospective matched cohort stu...
Source: PLoS One - September 11, 2023 Category: Biomedical Science Authors: Chiu-Hsia Su Source Type: research
Exploring the Biomedical Applications of Biosynthesized Silver Nanoparticles Using < em > Perilla frutescens < /em > Flavonoid Extract: Antibacterial, Antioxidant, and Cell Toxicity Properties against Colon Cancer Cells
In this study, we also explained the plausible mechanisms of the biosynthesis, anticancer, and antibacterial effects of PFFE-AgNPs. Overall, these findings suggest that PFFE-AgNPs have potential as a multi-functional nanomaterial for biomedical applications, particularly in cancer therapy and infection control. However, it is important to note that further research is needed to determine the safety and efficacy of these nanoparticles in vivo, as well as to explore their potential in other areas of medicine.PMID:37687260 | DOI:10.3390/molecules28176431
Source: Cancer Control - September 9, 2023 Category: Cancer & Oncology Authors: Tianyu Hou Yurong Guo Wanyu Han Yang Zhou Vasudeva Reddy Netala Huizhen Li He Li Zhijun Zhang Source Type: research
Synergistic Role of Biofilm-Associated Genes and Efflux Pump Genes in Tigecycline Resistance of Acinetobacter baumannii
CONCLUSIONS The biofilm formation of A. baumannii may be positively related to tigecycline resistance ability because of the co-expression of the bfs gene and the AdeB efflux pump gene. The enhanced transcription level of bfs and AdeB promotes biofilm formation to improve the resistance of A. baumannii to tigecycline.PMID:37688296 | DOI:10.12659/MSM.940704
Source: Medical Science Monitor - September 9, 2023 Category: Research Authors: Bin Luo Zhiwei Li Qian Wang Changmin Wang Source Type: research
