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Vaccination: Whooping Cough (Pertussis) Vaccine
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Status of New Vaccine Introduction - Worldwide, 2016-2021
This report describes the status of introductions globally for eight World Health Organization (WHO)-recommended new and underutilized vaccines, comprising 10 individual vaccine antigens. By 2021, among 194 countries worldwide, 33 (17%) provided all of these 10 WHO-recommended antigens as part of their routine immunization schedules; only one low-income country had introduced all of these recommended vaccines. Universal hepatitis B birth dose; human papillomavirus vaccine; rotavirus vaccine; and diphtheria, tetanus, and pertussis-containing vaccine first booster dose have been introduced by 57%, 59%, 60%, and 72% of all co...
Source: MMWR Morb Mortal Wkl... - July 6, 2023 Category: Epidemiology Authors: Gurpreet Kaur Rebecca M Casey Jaymin C Patel Paul Bloem Jenny A Walldorf Terri B Hyde Source Type: research
Long-term outcome in Vaccine-induced Immune Thrombocytopenia and Thrombosis
CONCLUSION: Once the acute episode of VITT has passed, patients appear to be at low risk for recurrent thrombosis and/or thrombocytopenia.PMID:37394120 | DOI:10.1016/j.jtha.2023.06.027
Source: Thrombosis and Haemostasis - July 2, 2023 Category: Hematology Authors: Linda Sch önborn Sabrina E Seck Thomas Thiele Lars Kaderali Till Hoffmann Annalena Hlinka Edelgard Lindhoff-Last Uwe V ölker Kathleen Selleng Alessandra Buoninfante Marco Cavaleri Andreas Greinacher Source Type: research
Barriers to and facilitators of populational adherence to prevention and control measures of COVID-19 and other respiratory infectious diseases: a qualitative evidence synthesis
CONCLUSIONS: This review suggests that financial and social support, assertive communication, trust in political authorities and greater regulation of social media enhance adherence to prevention and control measures for COVID-19 and infectious respiratory diseases. Designing and implementing effective educational public health interventions targeting the findings of barriers and facilitators highlighted in this review are key to reducing the impact of infectious respiratory diseases at the population level.PMID:37343960 | DOI:10.1183/16000617.0238-2022
Source: Respiratory Care - June 21, 2023 Category: Respiratory Medicine Authors: T ácito Zaildo Thayla Amorim Santino Gabriela Chaves Baldomero Antonio Kato da Silva Jo ão Carlos Alchieri Cecilia M Patino Sarah Leite Kleber Giovanni Luz Ricardo Oliveira Guerra Tito Hugo Soares da Penha Gabriel Rodrigues da Silva Ada Cristina J ácom Source Type: research
A phase 2 randomized controlled dose-ranging trial of recombinant pertussis booster vaccines containing genetically inactivated pertussis toxin in pregnant women
CONCLUSIONS: Vaccine formulations containing PTgen were safe and immunogenic in pregnant women. The ap1gen vaccine, with the lowest cost and reactogenicity, may be suitable for use in pregnant women when diphtheria and tetanus toxoids are not needed. This study is registered in the Thai Clinical Trial Registry (www.CLINICALTRIALS: in.th), number TCTR20180725004.PMID:37330371 | DOI:10.1016/j.vaccine.2023.06.001
Source: Vaccine - June 17, 2023 Category: Allergy & Immunology Authors: Thanyawee Puthanakit Kulkanya Chokephaibulkit Surasith Chaithongwongwatthana Niranjan Bhat Yuxiao Tang Suvaporn Anugulruengkitt Chenchit Chayachinda Sanitra Anuwutnavin Keswadee Lapphra Supattra Rungmaitree Monta Tawan Indah Andi-Lolo Renee Holt Librada F Source Type: research
Bordetella bronchiseptica and Bordetella pertussis: Similarities and Differences in Infection, Immuno-Modulation, and Vaccine Considerations
Clin Microbiol Rev. 2023 Jun 12:e0016422. doi: 10.1128/cmr.00164-22. Online ahead of print.ABSTRACTBordetella pertussis and Bordetella bronchiseptica belong to the genus Bordetella, which comprises 14 other species. B. pertussis is responsible for whooping cough in humans, a severe infection in children and less severe or chronic in adults. These infections are restricted to humans and currently increasing worldwide. B. bronchiseptica is involved in diverse respiratory infections in a wide range of mammals. For instance, the canine infectious respiratory disease complex (CIRDC), characterized by a chronic cough in dogs. At...
Source: Clinical Microbiology Reviews - June 12, 2023 Category: Microbiology Authors: Beatriz Miguelena Chamorro Karelle De Luca Gokul Swaminathan St éphanie Longet Egbert Mundt St éphane Paul Source Type: research
Nasal vaccines for pertussis
Curr Opin Immunol. 2023 Jun 10;84:102355. doi: 10.1016/j.coi.2023.102355. Online ahead of print.ABSTRACTWhooping cough, caused by Bordetella pertussis, is still a major cause of morbidity and mortality worldwide. Current acellular pertussis (aP) vaccines induce potent circulating IgG and prevent severe disease in children/adults and in infants born to vaccinated mothers. However, they do not prevent nasal infection, allowing asymptomatic transmission of B. pertussis. Studies in animal models have demonstrated that, unlike natural infection, immunization with aP vaccines fails to induce secretory immunoglobulin A (IgA) or i...
Source: Current Opinion in Immunology - June 12, 2023 Category: Allergy & Immunology Authors: Pauline Schmitt Lisa Borkner Seyed Davoud Jazayeri Karen N McCarthy Kingston Hg Mills Source Type: research
Bordetella bronchiseptica and Bordetella pertussis: Similarities and Differences in Infection, Immuno-Modulation, and Vaccine Considerations
Clin Microbiol Rev. 2023 Jun 12:e0016422. doi: 10.1128/cmr.00164-22. Online ahead of print.ABSTRACTBordetella pertussis and Bordetella bronchiseptica belong to the genus Bordetella, which comprises 14 other species. B. pertussis is responsible for whooping cough in humans, a severe infection in children and less severe or chronic in adults. These infections are restricted to humans and currently increasing worldwide. B. bronchiseptica is involved in diverse respiratory infections in a wide range of mammals. For instance, the canine infectious respiratory disease complex (CIRDC), characterized by a chronic cough in dogs. At...
Source: Clinical Microbiology Reviews - June 12, 2023 Category: Microbiology Authors: Beatriz Miguelena Chamorro Karelle De Luca Gokul Swaminathan St éphanie Longet Egbert Mundt St éphane Paul Source Type: research
Nasal vaccines for pertussis
Curr Opin Immunol. 2023 Jun 10;84:102355. doi: 10.1016/j.coi.2023.102355. Online ahead of print.ABSTRACTWhooping cough, caused by Bordetella pertussis, is still a major cause of morbidity and mortality worldwide. Current acellular pertussis (aP) vaccines induce potent circulating IgG and prevent severe disease in children/adults and in infants born to vaccinated mothers. However, they do not prevent nasal infection, allowing asymptomatic transmission of B. pertussis. Studies in animal models have demonstrated that, unlike natural infection, immunization with aP vaccines fails to induce secretory immunoglobulin A (IgA) or i...
Source: Current Opinion in Immunology - June 12, 2023 Category: Allergy & Immunology Authors: Pauline Schmitt Lisa Borkner Seyed Davoud Jazayeri Karen N McCarthy Kingston Hg Mills Source Type: research
Bordetella bronchiseptica and Bordetella pertussis: Similarities and Differences in Infection, Immuno-Modulation, and Vaccine Considerations
Clin Microbiol Rev. 2023 Jun 12:e0016422. doi: 10.1128/cmr.00164-22. Online ahead of print.ABSTRACTBordetella pertussis and Bordetella bronchiseptica belong to the genus Bordetella, which comprises 14 other species. B. pertussis is responsible for whooping cough in humans, a severe infection in children and less severe or chronic in adults. These infections are restricted to humans and currently increasing worldwide. B. bronchiseptica is involved in diverse respiratory infections in a wide range of mammals. For instance, the canine infectious respiratory disease complex (CIRDC), characterized by a chronic cough in dogs. At...
Source: Clinical Microbiology Reviews - June 12, 2023 Category: Microbiology Authors: Beatriz Miguelena Chamorro Karelle De Luca Gokul Swaminathan St éphanie Longet Egbert Mundt St éphane Paul Source Type: research
