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Vaccination: Whooping Cough (Pertussis) Vaccine

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Total 1106 results found since Jan 2013.

Development and validation of a spectrophotometric method for quantification of residual cyclodextrin (DIMEB; Heptakis) in pertussis antigens
We report here development and validation of a spectrophotometric method for estimation of DIMEB in different product matrices of pertussis vaccine antigens i.e. Filamentous haemagglutinin (FHA), Pertactin (PRN) and Pertussis toxin (PT). The detection is based on characteristic reaction of hydrolyzed sugars derivatives from DIMEB i.e., furfural derivatives with anthrone reagent to form colored complexes which could be quantified at 625 nm. Method showed excellent linearity with correlation coefficient (R2) > 0.995 over the concentration of 5.0-80.0 μg. LOD and LOQ of 1.47 μg and 4.46 μg respectively was reported. The...
Source: Biologicals : Journal of the International Association of Biological Standardization - February 15, 2023 Category: Biotechnology Authors: Bharat Shinde Dadasaheb Patil Vinod Nandre Manish Gautam Pooja Doshi Sunil Gairola Source Type: research

Evaluation of the effectiveness of maternal immunization against pertussis in Alberta using agent-based modeling: A Canadian immunization research network study
CONCLUSIONS: Our model predicts significant reduction in future pertussis cases in infants due to maternal vaccination, with immunological blunting slightly moderating its effectiveness. The model is most sensitive to maternal vaccination coverage. The interruption of exposure pathways plays a role in the reduction of pertussis burden in infants due to maternal immunization. The effect of maternal immunization on population other than infants remains to be elucidated.PMID:36775775 | DOI:10.1016/j.vaccine.2022.12.071
Source: Vaccine - February 12, 2023 Category: Allergy & Immunology Authors: Karsten Hempel Wade McDonald Nathaniel D Osgood David Fisman Scott A Halperin Natasha Crowcroft Nicola P Klein Pejman Rohani Alexander Doroshenko Source Type: research

Influence of the COVID-19 pandemic and social media on the behaviour of pregnant and lactating women towards vaccination: a scoping review
Discussion and conclusion Vaccine hesitancy in pregnant and lactating women remains an important issue, expressing the need for effective interventions to increase vaccine confidence and coverage. The role social media plays in vaccine uptake remains unclear.
Source: BMJ Open - February 10, 2023 Category: General Medicine Authors: De Brabandere, L., Hendrickx, G., Poels, K., Daelemans, W., Van Damme, P., Maertens, K. Tags: Open access, Public health, COVID-19 Source Type: research

Mapping the delivery of interventions for vaccine-preventable infections in pregnancy in Victoria, Australia
CONCLUSION: Coordinated and standardised system and clinical care improvements are required to provide equitable care for pregnant women and their infants, including training and education for healthcare providers, improving data capture and communication among health services.PMID:36740448 | DOI:10.1071/PY22158
Source: Primary Care - February 5, 2023 Category: Primary Care Authors: Nafisa Yussf Nicole Allard Nicole Romero Ann Wilson Jack Wallace Meg Perrier Stacey Rowe Rosemary Morey Neylan Aykut Benjamin Cowie Source Type: research

Trends and characteristics of Tdap vaccination during pregnancy in Ontario, Canada: a retrospective cohort study
We described Tdap vaccination patterns in pregnancy for the entire study period and before and after the NACI recommendation. We used log-binomial regression to identify characteristics associated with Tdap vaccination during pregnancy.RESULTS: Among the 991 850 deliveries included, 7.0% of pregnant individuals received the Tdap vaccination during pregnancy. Vaccine coverage increased from 0.4% in 2011/12 to 29.2% in 2019/20. Coverage was highest among individuals who were older, had no previous live births, had adequate prenatal care and received maternity care primarily from a family physician. After adjustment, characte...
Source: cmaj - February 3, 2023 Category: General Medicine Authors: Romina Fakhraei Stephen G Fung William Petrcich Natasha Crowcroft Shelly Bolotin Laura Gaudet Gayatri Amirthalingam Anne Biringer Kumanan Wilson Vinita Dubey Scott A Halperin Frances Jamieson Jeffrey C Kwong Manish Sadarangani Jocelynn Cook Steven Hawken Source Type: research