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Vaccination: Whooping Cough (Pertussis) Vaccine
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Total 1106 results found since Jan 2013.
Impact of methotrexate treatment on vaccines immunogenicity in adult rheumatological patients - Lessons learned from the COVID-19 pandemic
Biomed Pharmacother. 2023 Aug 3;165:115254. doi: 10.1016/j.biopha.2023.115254. Online ahead of print.ABSTRACTDespite the development of new biological and synthetic targeted therapies, methotrexate remains one of the most commonly used immunomodulatory drugs in rheumatology. However, its effect on the immunogenicity of vaccines has been studied only to a limited extent until recently, resulting in the lack of clear guidelines on the use of methotrexate during vaccination. Significant progress was made during the COVID-19 pandemic due to the dynamic development of research on vaccines, including patients with autoimmune inf...
Source: Herpes - August 5, 2023 Category: Infectious Diseases Authors: Jakub Wro ński Marzena Ciechomska Ewa Kuca-Warnawin Source Type: research
Modeling the impact of vaccination for the immunization Agenda 2030: Deaths averted due to vaccination against 14 pathogens in 194 countries from 2021 to 2030
Vaccine. 2023 Aug 1:S0264-410X(23)00854-X. doi: 10.1016/j.vaccine.2023.07.033. Online ahead of print.ABSTRACTBACKGROUND: The Immunization Agenda 2030 (IA2030) Impact Goal 1.1. aims to reduce the number of future deaths averted through immunization in the next decade. To estimate the potential impact of the aspirational coverage targets for IA2030, we developed an analytical framework and estimated the number of deaths averted due to an ambitious vaccination coverage scenario from 2021 to 2030 in 194 countries.METHOD: A demographic model was used to determine annual age-specific mortality estimates associated with vaccine c...
Source: Vaccine - August 3, 2023 Category: Allergy & Immunology Authors: Austin Carter William Msemburi So Yoon Sim Katy A M Gaythorpe Philipp Lambach Ann Lindstrand Raymond Hutubessy Source Type: research
Variability of in vivo potency assays of whole-cell pertussis, inactivated polio, and meningococcal B vaccines
Vaccine. 2023 Jul 30:S0264-410X(23)00885-X. doi: 10.1016/j.vaccine.2023.07.054. Online ahead of print.ABSTRACTFor the batch release of vaccines, potency release assays are required. Non-animal in vitro tests have numerous advantages and are preferred; however, several vaccines are still released using in vivo assays. Their major drawback is the inherent variability with its practical implications. We quantified the variability of in vivo potency release assays for whole-cell pertussis, inactivated polio and meningococcal B (MenB) vaccines which showed large CV (Coefficient of Variation) ranging from 34% to 125%. As inheren...
Source: Vaccine - August 1, 2023 Category: Allergy & Immunology Authors: Cerissa van Walstijn Stefan Verweij Rory Care Peter Rigsby Eli-Boaz Clapper Kevin Markey Rob J Vandebriel Paul Stickings Marcel H N Hoefnagel Source Type: research
T cell reactivity to Bordetella pertussis is highly diverse regardless of childhood vaccination
Cell Host Microbe. 2023 Jul 16:S1931-3128(23)00266-4. doi: 10.1016/j.chom.2023.06.015. Online ahead of print.ABSTRACTThe incidence of whooping cough due to Bordetella pertussis (BP) infections has increased recently. It is believed that the shift from whole-cell pertussis (wP) vaccines to acellular pertussis (aP) vaccines may be contributing to this rise. While T cells are key in controlling and preventing disease, nearly all knowledge relates to antigens in aP vaccines. A whole-genome mapping of human BP-specific CD4+ T cell responses was performed in healthy vaccinated adults and revealed unexpected broad reactivity to h...
Source: Cell Host and Microbe - July 25, 2023 Category: Microbiology Authors: Ricardo da Silva Antunes Emily Garrigan Lorenzo G Quiambao Sandeep Kumar Dhanda Daniel Marrama Luise Westernberg Eric Wang Adam Abawi Aaron Sutherland Sandra K Armstrong Timothy J Brickman John Sidney April Frazier Tod J Merkel Bjoern Peters Alessandro Se Source Type: research
TWiV 1026: Debunking RFK Jr. ’s vaccine funk with Dan Wilson
Dan Wilson returns to TWiV to debunk vaccine misinformation by RFK Jr. during his recent appearance on the Joe Rogan Experience. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Guest: Dan Wilson Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Joe Rogan’s worst misinformation yet, with RFK Jr. (YouTube) Every first vaccine has been tested in placebo-controlled trials before going to market. Polio Measles HPV COVID-19 HepB Haemophilus influenzae B Pertussis Diphtheria Tetanus...
Source: This Week in Virology - MP3 Edition - July 16, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Lower risk for COVID-19 hospitalization among patients in the United States with past vaccinations for herpes zoster and tetanus, diphtheria and pertussis
Prev Med Rep. 2023 Jun 25;35:102302. doi: 10.1016/j.pmedr.2023.102302. eCollection 2023 Oct.ABSTRACTInfluenza, tetanus, diphtheria, and herpes zoster (HZ) vaccination received within 10 years of the COVID-19 pandemic have been associated with less severe COVID-19 infection. We expanded on this evidence to determine if a receiving two different vaccinations (i.e., HZ and tetanus, diphtheria, and pertussis (Tdap)) was associated with a lower risk for COVID-19 hospitalization. De-identified medical record data from a large mid-western health care system was used to determine if, compared to those with neither HZ or Tdap vacci...
Source: Herpes - July 13, 2023 Category: Infectious Diseases Authors: Joanne Salas John E Morley Daniel F Hoft Jeffrey F Scherrer Source Type: research
Status of New Vaccine Introduction - Worldwide, 2016-2021
This report describes the status of introductions globally for eight World Health Organization (WHO)-recommended new and underutilized vaccines, comprising 10 individual vaccine antigens. By 2021, among 194 countries worldwide, 33 (17%) provided all of these 10 WHO-recommended antigens as part of their routine immunization schedules; only one low-income country had introduced all of these recommended vaccines. Universal hepatitis B birth dose; human papillomavirus vaccine; rotavirus vaccine; and diphtheria, tetanus, and pertussis-containing vaccine first booster dose have been introduced by 57%, 59%, 60%, and 72% of all co...
Source: MMWR Morb Mortal Wkl... - July 6, 2023 Category: Epidemiology Authors: Gurpreet Kaur Rebecca M Casey Jaymin C Patel Paul Bloem Jenny A Walldorf Terri B Hyde Source Type: research
