Trends and characteristics of Tdap vaccination during pregnancy in Ontario, Canada: a retrospective cohort study

We described Tdap vaccination patterns in pregnancy for the entire study period and before and after the NACI recommendation. We used log-binomial regression to identify characteristics associated with Tdap vaccination during pregnancy.RESULTS: Among the 991 850 deliveries included, 7.0% of pregnant individuals received the Tdap vaccination during pregnancy. Vaccine coverage increased from 0.4% in 2011/12 to 29.2% in 2019/20. Coverage was highest among individuals who were older, had no previous live births, had adequate prenatal care and received maternity care primarily from a family physician. After adjustment, characteristics associated with lower coverage included younger maternal age, having a multiple birth, residing in a rural location and higher area material deprivation. In 2019/20, 71.0% of vaccinated individuals received the Tdap vaccination during the recommended gestational window (27-32 wk). Stratified analyses of the pre- and postrecommendation cohorts yielded similar findings to the main analyses with a few gradient differences after adjustment.INTERPRETATION: During pregnancy, Tdap vaccination coverage increased substantially in Ontario between 2011/12 and 2019/20, most notably after recommendations for universal Tdap vaccination during pregnancy began in Canada. To further improve vaccine coverage in the obstetric setting, public health strategies should consider tailoring their programs to reach subpopulations with lower vaccine coverage.PMID:36735222 | DO...

Source: cmaj - February 3, 2023 Category: General Medicine Authors: Romina Fakhraei Stephen G Fung William Petrcich Natasha Crowcroft Shelly Bolotin Laura Gaudet Gayatri Amirthalingam Anne Biringer Kumanan Wilson Vinita Dubey Scott A Halperin Frances Jamieson Jeffrey C Kwong Manish Sadarangani Jocelynn Cook Steven Hawken Source Type: research