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Vaccination: Meningitis Vaccine

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Total 2891 results found since Jan 2013.

Biodistribution assessment of cationic pullulan nanogel, a nasal vaccine delivery system, in mice and non-human primates
Vaccine. 2023 Jun 27:S0264-410X(23)00754-5. doi: 10.1016/j.vaccine.2023.06.065. Online ahead of print.ABSTRACTCationic cholesteryl-group-bearing pullulan nanogel (cCHP-nanogel) is an effective drug-delivery system for nasal vaccines. However, cCHP-nanogel-based nasal vaccines might access the central nervous system due to its close proximity via the olfactory bulb in the nasal cavity. Using real-time quantitative tracking of the nanogel-based nasal botulinum neurotoxin and pneumococcal vaccines, we previously confirmed the lack of deposition of vaccine antigen in the cerebrum or olfactory bulbs of mice and non-human primat...
Source: Vaccine - June 29, 2023 Category: Allergy & Immunology Authors: Yoshikazu Yuki Norihiro Harada Shin-Ichi Sawada Yohei Uchida Rika Nakahashi-Ouchida Hiromi Mori Tomoyuki Yamanoue Tomonori Machita Masakatsu Kanazawa Dai Fukumoto Hiroyuki Ohba Takashi Miyazaki Kazunari Akiyoshi Kohtaro Fujihashi Hiroshi Kiyono Source Type: research

Marketing Two Immunization Services at a Regional Supermarket Chain Pharmacy
Conclusions: The pilot project incorporated personal selling into the dispensing workflow and, although no vaccines were given, provided valuable lessons. The full study demonstrated that personal selling alone and personal selling combined with automated telephone calls were associated with higher vaccine delivery rates.PMID:37368429 | DOI:10.3390/pharmacy11030103
Source: Herpes - June 27, 2023 Category: Infectious Diseases Authors: Megan A Hedden Yifei Liu Peggy G Kuehl Sarah M Oprinovich Source Type: research

Reducing the risk of infections in hereditary and acquired complement deficiencies.
Orv Hetil. 2023 Jun 25;164(25):971-980. doi: 10.1556/650.2023.32798. Print 2023 Jun 25.ABSTRACTHereditary complement deficiencies are relatively rare worldwide, they account for about 1-10% of primary immunodeficiencies. Acquired complement deficiencies are more prevalent and with the more frequent use of complement inhibitor therapy, the incidence of patients with iatrogenic complement deficiency is increasing. Alike in the inherited forms, patients have a high risk of severe and life-threatening infections caused by encapsulated bacteria (sepsis, meningitis). The most frequent pathogens are Neisseria meningitidis, Strept...
Source: Orvosi Hetilap - June 25, 2023 Category: General Medicine Authors: Éva Karászi Be áta Onozó Andrea Kulcs ár J ános Szlávik Vera Goda Gergely Kriv án Zolt án Prohászka Botond Lakatos Source Type: research

The impact of implementing the 10-valent pneumococcal conjugate vaccine on hospitalizations for pneumonia among children
In conclusion, in the five years following implementation of PCV-10, hospitalizations of children with pneumonia in Pernambuco decrease by 22%.PMID:37353456 | DOI:10.1016/j.vaccine.2023.06.049
Source: Vaccine - June 23, 2023 Category: Allergy & Immunology Authors: Ana Catarina de Melo Araujo Jamilly da Silva Arag ão Wayner Vieira de Souza Laura Cunha Rodrigues Dem ócrito de Barros Miranda-Filho Source Type: research

Dynamics of invasive pneumococcal disease in infants & lt;  2 years old following PCV7/13 implementation using two infant and a booster dose schedule: evidence for indirect protection of young infants, Israel, 2004 to 2019
ConclusionsIndirect (herd) protection of infants, including < 4 month-olds with ≤ 1 PCV dose, was achieved by the 2+1 PCV schedule programme which thus seems adequate.PMID:37347413 | PMC:PMC10288828 | DOI:10.2807/1560-7917.ES.2023.28.25.2200765
Source: Euro Surveill - June 22, 2023 Category: Infectious Diseases Authors: Shalom Ben-Shimol Bart Adriaan van der Beek Meirav Mor Orli Megged Ron Dagan Israeli Pediatric Bacteremia and Meningitis Group (IPBMG) and the Microbiology Group Source Type: research

A novel immuno-molecular strategy for the detection of Streptococcus pneumoniae serotypes in human cerebrospinal and middle ear fluids
J Immunol Methods. 2023 Jun 20:113516. doi: 10.1016/j.jim.2023.113516. Online ahead of print.ABSTRACTStreptococcus pneumoniae is one of the most common microorganisms causing acute otitis media (AOM) in children. While bacterial culture of middle ear fluid (MEF) is the gold standard to detect the etiological organisms, several host and pathogen factors impact the survival of the organisms resulting in false negatives. To overcome this limitation, we have developed and validated an innovative multiplex immuno-molecular assay to screen and detect the S. pneumoniae 15-valent pneumococcal conjugate vaccine (PCV15; STs 1, 3, 4,...
Source: Journal of Immunological Methods - June 22, 2023 Category: Allergy & Immunology Authors: Gowrisankar Rajam Kate L Hicks Joseph M Antonello Yuhua Zhang Sarah Irey Julia Kelly Stephanie Cooper Leonard J Rubinstein Source Type: research

Dynamics of invasive pneumococcal disease in infants & lt;  2 years old following PCV7/13 implementation using two infant and a booster dose schedule: evidence for indirect protection of young infants, Israel, 2004 to 2019
ConclusionsIndirect (herd) protection of infants, including < 4 month-olds with ≤ 1 PCV dose, was achieved by the 2+1 PCV schedule programme which thus seems adequate.PMID:37347413 | DOI:10.2807/1560-7917.ES.2023.28.25.2200765
Source: Euro Surveill - June 22, 2023 Category: Infectious Diseases Authors: Shalom Ben-Shimol Bart Adriaan van der Beek Meirav Mor Orli Megged Ron Dagan Israeli Pediatric Bacteremia and Meningitis Group (IPBMG) and the Microbiology Group Source Type: research

A novel immuno-molecular strategy for the detection of Streptococcus pneumoniae serotypes in human cerebrospinal and middle ear fluids
J Immunol Methods. 2023 Jun 20:113516. doi: 10.1016/j.jim.2023.113516. Online ahead of print.ABSTRACTStreptococcus pneumoniae is one of the most common microorganisms causing acute otitis media (AOM) in children. While bacterial culture of middle ear fluid (MEF) is the gold standard to detect the etiological organisms, several host and pathogen factors impact the survival of the organisms resulting in false negatives. To overcome this limitation, we have developed and validated an innovative multiplex immuno-molecular assay to screen and detect the S. pneumoniae 15-valent pneumococcal conjugate vaccine (PCV15; STs 1, 3, 4,...
Source: Journal of Immunological Methods - June 22, 2023 Category: Allergy & Immunology Authors: Gowrisankar Rajam Kate L Hicks Joseph M Antonello Yuhua Zhang Sarah Irey Julia Kelly Stephanie Cooper Leonard J Rubinstein Source Type: research