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Vaccination: Meningitis Vaccine

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Total 2891 results found since Jan 2013.

Surveillance of Neisseria meningitidis carriage four years after menACWY vaccine implementation in the Netherlands reveals decline in vaccine-type and rise in genogroup e circulation
Vaccine. 2023 Jul 7:S0264-410X(23)00781-8. doi: 10.1016/j.vaccine.2023.06.078. Online ahead of print.ABSTRACTCarriage of Neisseria meningitidisis an accepted endpoint in monitoring meningococcal vaccine effects. We applied molecular methods to assess the impact of menACWY vaccine implementation on meningococcal carriage and genogroup-specific prevalence in young adults in Fall of 2022, four years after the introduction of the tetravalent vaccine in the Netherlands. The overall carriage rate of genogroupable meningococci was not significantly different compared to a pre-menACWY cohort investigated in 2018 (20.8 % or 125 of ...
Source: Vaccine - July 9, 2023 Category: Allergy & Immunology Authors: Willem R Miellet Gerlinde Pluister Meike Sikking Marcia Tappel Jurgen Karczewski Linda J Visser Thijs Bosch Krzysztof Trzci Ĺ„ski Rob Mariman Source Type: research

Status of New Vaccine Introduction - Worldwide, 2016-2021
This report describes the status of introductions globally for eight World Health Organization (WHO)-recommended new and underutilized vaccines, comprising 10 individual vaccine antigens. By 2021, among 194 countries worldwide, 33 (17%) provided all of these 10 WHO-recommended antigens as part of their routine immunization schedules; only one low-income country had introduced all of these recommended vaccines. Universal hepatitis B birth dose; human papillomavirus vaccine; rotavirus vaccine; and diphtheria, tetanus, and pertussis-containing vaccine first booster dose have been introduced by 57%, 59%, 60%, and 72% of all co...
Source: MMWR Morb Mortal Wkl... - July 6, 2023 Category: Epidemiology Authors: Gurpreet Kaur Rebecca M Casey Jaymin C Patel Paul Bloem Jenny A Walldorf Terri B Hyde Source Type: research

Non-protective immunity after standard pneumococcal vaccination series identified as a potential contributing risk factor for refractory otolaryngologic conditions in children
CONCLUSION: In pediatric patients with recurrent infectious otolaryngologic disease refractory to traditional medical and surgical therapy, inadequate responses to pneumococcal vaccination may be revealed. This correlation represents a potential pathway for diagnosis and therapy.PMID:37386844 | DOI:10.1177/00034894231182745
Source: The Annals of Otology, Rhinology, and Laryngology - June 30, 2023 Category: ENT & OMF Authors: Caroline A Bonaventure Adele K Evans Source Type: research

Evaluation of structural modification induced activation of pneumococcal polysaccharide by GC-MS for the conjugate vaccine
Carbohydr Res. 2023 Jun 25;531:108878. doi: 10.1016/j.carres.2023.108878. Online ahead of print.ABSTRACTPolysaccharide (Ps) activation evaluation is an imperative quality attribute in a conjugate vaccine. Pneumococcal polysaccharide (PnPs) serotypes 5, 6B, 14, 19A and 23F were cyanylated for 3 and 8 min. The cyanylated and non-cyanylated polysaccharides were methanolysed and derivatized to assess the activation of each sugar by GC-MS. The activation of 22 and 27% serotype 6B and 11 and 36% in serotype 23 F Ps at 3 and 8 min respectively showed controlled conjugation kinetics with CRM197 carrier protein estimated by SEC-HPL...
Source: Carbohydrate Research - June 30, 2023 Category: Genetics & Stem Cells Authors: Niraj Shende Abhijeet Karale Prashant Bore Sudhakar Bhagade Ashishkumar Gulhane Asha D Mallya Rajeev M Dhere Source Type: research