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Vaccination: Meningitis Vaccine

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Total 2891 results found since Jan 2013.

Challenges in synthesis of real-world vaccine effects on meningococcal serogroup B disease for 4CMenB vaccine post-licensure effectiveness studies: A systematic review
CONCLUSION: Both vaccine outcomes showed real-life effectiveness of 4CMenB vaccine despite differences in study methodologies and vaccination strategies. Based on appraisal of study methods, we highlighted the need for an adapted tool which facilitates synthesis of heterogenic real-world vaccine studies when quantitative pooling methods are not applicable.PMID:37321895 | DOI:10.1016/j.vaccine.2023.05.025
Source: Vaccine - June 15, 2023 Category: Allergy & Immunology Authors: Elisa Cinconze Dominique Rosillon Rino Rappuoli Kumaran Vadivelu Rafik Bekkat-Berkani Victoria Abbing-Karahagopian Source Type: research

Impact of aluminum adjuvants on the stability of pneumococcal polysaccharide-protein conjugate vaccines
This study suggests a formulation, which includes AAHS, may negatively impact the stability of a pneumococcal polysaccharide-protein conjugate vaccine that contains phosphodiester groups. This decrease in stability would likely result in a decrease in the "active" concentration of antigen dose, and herein, it is shown that such instability directly compromised vaccine immunogenicity in an animal model. The results presented in this study help to explain critical degradation mechanisms of pneumococcal polysaccharide-protein conjugate vaccines.PMID:37321893 | DOI:10.1016/j.vaccine.2023.05.059
Source: Vaccine - June 15, 2023 Category: Allergy & Immunology Authors: William J Smith Rachel Thompson Patricia M Egan Yuhua Zhang Lani Indrawati Julie M Skinner Jeffrey T Blue Michael A Winters Source Type: research

Acceptance, availability, and feasibility of RTS, S/AS01 malaria vaccine: A review
ConclusionSeveral challenges need to be addressed to ensure the success of vaccination programs. From the acceptability perspective, issues such as inadequate community engagement, concerns about side effects, and issues with the delivery and quality of healthcare services can affect the acceptance of the vaccine. From the feasibility standpoint, factors such as lack of transportation or long distances to healthcare facilities and the perception of completion of the vaccination calendar can affect the feasibility of the vaccine. Lastly, the availability of the vaccine is also a major concern as it may not be readily availa...
Source: Immunity, Inflammation and Disease - June 14, 2023 Category: Allergy & Immunology Authors: Hassan Mumtaz, Abdullah Nadeem, Wajeeha Bilal, Farrukh Ansar, Saira Saleem, Qaisar Ali Khan, Tamara Tango, Christopher Farkouh, Naod F. Belay, Ravina Verma, Matthew Farkouh, Muhammad Saqib Tags: REVIEW ARTICLE Source Type: research

Cost-effectiveness of an in-development adult-formulated pneumococcal vaccine in older US adults
CONCLUSION: An in-development PCV21 vaccine would likely be economically and clinically favorable compared to currently recommended pneumococcal vaccines in older adults. While PCV21 was more favorable in Black cohort analyses, results for both Black and non-Black populations were economically reasonable, highlighting the potential importance of adult-specific pneumococcal vaccine formulations and, pending further investigation, potentially justifying a future general population recommendation for PCV21 use in older adults.PMID:37316409 | DOI:10.1016/j.vaccine.2023.06.007
Source: Vaccine - June 14, 2023 Category: Allergy & Immunology Authors: Angela R Wateska Mary Patricia Nowalk Chyongchiou J Lin Lee H Harrison William Schaffner Richard K Zimmerman Kenneth J Smith Source Type: research

Predictors of serological non-response to the 13-valent pneumococcal conjugate vaccine followed by the 23-valent polysaccharide vaccine among adults living with HIV
CONCLUSION: Less than half of our study population achieved anti-pneumococcal seroprotective levels following PCV13 and PPV23 immunization. Low pre-vaccination GMC levels were associated with non-response. Further research is required to optimize vaccination strategies that achieve higher seroprotection in this high-risk group.PMID:37316406 | DOI:10.1016/j.vaccine.2023.06.021
Source: Vaccine - June 14, 2023 Category: Allergy & Immunology Authors: Michaela Tinggaard Hans-Christian Slotved Charlotte Sv ærke Jørgensen Gitte Kronborg Thomas Benfield Source Type: research

Cost-effectiveness of an in-development adult-formulated pneumococcal vaccine in older US adults
CONCLUSION: An in-development PCV21 vaccine would likely be economically and clinically favorable compared to currently recommended pneumococcal vaccines in older adults. While PCV21 was more favorable in Black cohort analyses, results for both Black and non-Black populations were economically reasonable, highlighting the potential importance of adult-specific pneumococcal vaccine formulations and, pending further investigation, potentially justifying a future general population recommendation for PCV21 use in older adults.PMID:37316409 | DOI:10.1016/j.vaccine.2023.06.007
Source: Vaccine - June 14, 2023 Category: Allergy & Immunology Authors: Angela R Wateska Mary Patricia Nowalk Chyongchiou J Lin Lee H Harrison William Schaffner Richard K Zimmerman Kenneth J Smith Source Type: research

Predictors of serological non-response to the 13-valent pneumococcal conjugate vaccine followed by the 23-valent polysaccharide vaccine among adults living with HIV
CONCLUSION: Less than half of our study population achieved anti-pneumococcal seroprotective levels following PCV13 and PPV23 immunization. Low pre-vaccination GMC levels were associated with non-response. Further research is required to optimize vaccination strategies that achieve higher seroprotection in this high-risk group.PMID:37316406 | DOI:10.1016/j.vaccine.2023.06.021
Source: Vaccine - June 14, 2023 Category: Allergy & Immunology Authors: Michaela Tinggaard Hans-Christian Slotved Charlotte Sv ærke Jørgensen Gitte Kronborg Thomas Benfield Source Type: research

Study on acute respiratory infection in children aged 1 year to 5 years-A hospital-based cross-sectional study
CONCLUSION: The studies regarding factors influencing ARI are relatively rare in an urban setting, thus this calls for more studies in urban areas. Health education can change the healthcare-seeking behavior and attitude of parents for preventing ARI-related deaths. Family physicians can play a significant role by educating caregivers of children and giving timely services. Promoting and ensuring exclusive breastfeeding practices, timely weaning after 6 months, and avoidance of bottle feeds can dramatically decrease the episodes of ARI.PMID:37312761 | PMC:PMC10259544 | DOI:10.4103/jfmpc.jfmpc_1748_22
Source: Primary Care - June 14, 2023 Category: Primary Care Authors: Anuna Vinod Resmi S Kaimal Source Type: research

Cryptogenic new-onset super-refractory status epilepticus following SARS-CoV-2 vaccination. A case report
CONCLUSION: It is crucial to report suspected adverse reactions associated with SARS-CoV-2 vaccination, thereby allowing continued monitoring of the risk/benefit ratio of vaccination.PMID:37303102 | DOI:10.33588/rn.7612.2022374
Source: Revista de Neurologia - June 12, 2023 Category: Neurology Authors: D Villagr án-Sancho A C Luque-Ambrosiani C Mayorga-Mor ón F J G ómez-Fernández J Arzalluz-Luque A Castela-Murillo F J Hern ández-Ramos M D Jim énez-Hernández A Palomino-Garc ía Source Type: research