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Total 117870 results found since Jan 2013.
Low interobserver agreement among subspecialised breast pathologists in evaluating HER2-low breast cancer
CONCLUSIONS: Subspecialised breast pathologists have suboptimal agreement for immunohistochemical evaluation of HLBC using the modified Ki-67 methodology. An urgent need remains for a new assay/algorithm to reliably evaluate HLBC.PMID:37714693 | DOI:10.1136/jcp-2023-209055
Source: Clinical Breast Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Gulisa Turashvili Yuan Gao Di Andy Ai Abdulwahab M Ewaz Sandra Gjorgova Gjeorgjievski Qun Wang Thi T A Nguyen Chao Zhang Xiaoxian Li Source Type: research
The Anesthesiology Physician-Scientist Pipeline: Current Status and Recommendations for Future Growth-An Initiative of the Anesthesia Research Council
Anesth Analg. 2023 Oct 1;137(4):728-742. doi: 10.1213/ANE.0000000000006520. Epub 2023 Sep 5.ABSTRACTThe limited number and diversity of resident physicians pursuing careers as physician-scientists in medicine has been a concern for many decades. The Anesthesia Research Council aimed to address the status of the anesthesiology physician-scientist pipeline, benchmarked against other medical specialties, and to develop strategic recommendations to sustain and expand the number and diversity of anesthesiology physician-scientists. The working group analyzed data from the Association of American Medical Colleges and the Nationa...
Source: Anesthesia and Analgesia - September 15, 2023 Category: Anesthesiology Authors: Charles W Emala Vivianne L Tawfik Meghan B Lane-Fall Paloma Toledo Cynthia A Wong Monica S Vavilala Lee A Fleisher Margaret Wood Source Type: research
Modelling the rate of trainees transitioning to Fellowship before achieving competence under the RANZCP's Alternative Assessment Pathway to the Objective Structured Clinical Examination
CONCLUSIONS: Given possible increases in pre-competent trainees progressing to Fellowship while alternatives to the OSCE are finalised, confidence in the RANZCP's training program demands robust public analyses of those alternatives.PMID:37714141 | DOI:10.1177/10398562231202120
Source: Australasian Psychiatry - September 15, 2023 Category: Psychiatry Authors: Andrew Amos Michael James Weightman Edward Miller Source Type: research
From the Flight Deck to the Bedside: Core Aviation Concepts Applied to Acute Care Physical Therapist Practice and Education
Phys Ther. 2023 Sep 15:pzad125. doi: 10.1093/ptj/pzad125. Online ahead of print.ABSTRACTThe health care industry has sought to reduce errors and patient harm by drawing upon human factors research developed largely in the aviation industry. However, literature that explicitly applies human factors concepts to physical therapist practice is scarce. Therefore, this clinical perspective highlights key concepts in aviation safety and training that should be considered for application to physical therapist education and practice in the acute care setting, including the law of primacy, pilot in command, crew resource management,...
Source: Physical Therapy - September 15, 2023 Category: Physiotherapy Authors: Michael J Shoemaker Sean M Collins Source Type: research
Digital twin-driven dynamic monitoring system of the upper limb force
In conclusion, our digital twin-driven system is of great importance for rehabilitation medicine, biomechanical scientific research and physical training, promoting the application of the digital twin in the human biomedical field.PMID:37713212 | DOI:10.1080/10255842.2023.2254881
Source: Computer Methods in Biomechanics and Biomedical Engineering - September 15, 2023 Category: Biomedical Engineering Authors: Yanbin Guo Yingbin Liu Wenxuan Sun Shuai Yu Xiao-Jian Han Xin-Hui Qu Guoping Wang Source Type: research
From strength to stamina: an examination of subsequent resistance and endurance training impact on mitochondrial adaptations and endurance performance
J Physiol. 2023 Sep 15. doi: 10.1113/JP285369. Online ahead of print.NO ABSTRACTPMID:37712567 | DOI:10.1113/JP285369
Source: The Journal of Physiology - September 15, 2023 Category: Physiology Authors: Nino Nikolovski Trishawna A Fongwoo Adam N Di Salvo Source Type: research
Decision tree analysis accurately predicts discharge destination after spinal cord injury rehabilitation
CONCLUSIONS: D-CART and A-CART showed comparable prediction accuracies. This suggests that, even during the early stages of rehabilitation, it is possible to predict the discharge destination.PMID:37714507 | DOI:10.1016/j.apmr.2023.08.010
Source: Health Physics - September 15, 2023 Category: Physics Authors: Chihiro Kato Osamu Uemura Yasunori Sato Tetsuya Tsuji Source Type: research
Functional outcome prediction after spinal cord injury using ensemble machine learning
CONCLUSIONS: Our study revealed that functional prognostication could be achieved using machine-learning methods with features present at the time of rehabilitation admission. Goals can be set at the beginning of rehabilitation. Moreover, our model can be utilized to evaluate advanced medical treatments, such as regenerative medicine.PMID:37714506 | DOI:10.1016/j.apmr.2023.08.011
Source: Health Physics - September 15, 2023 Category: Physics Authors: Chihiro Kato Osamu Uemura Yasunori Sato Tetsuya Tsuji Source Type: research
Effects of the menstrual cycle on EPOC and fat oxidation after low-volume high-intensity interval training
CONCLUSIONS: These results suggest that the menstrual cycle does not affect the increase in EPOC or fat oxidation after low-volume HIIT.PMID:37712928 | DOI:10.23736/S0022-4707.23.15209-1
Source: Health Physics - September 15, 2023 Category: Physics Authors: Akira Ishikawa Tomoka Matsuda Nodoka Ikegami Akiko Funaki Mizuki Yamada Kayoko Kamemoto Mikako Sakamaki-Sunaga Source Type: research
From the Flight Deck to the Bedside: Core Aviation Concepts Applied to Acute Care Physical Therapist Practice and Education
Phys Ther. 2023 Sep 15:pzad125. doi: 10.1093/ptj/pzad125. Online ahead of print.ABSTRACTThe health care industry has sought to reduce errors and patient harm by drawing upon human factors research developed largely in the aviation industry. However, literature that explicitly applies human factors concepts to physical therapist practice is scarce. Therefore, this clinical perspective highlights key concepts in aviation safety and training that should be considered for application to physical therapist education and practice in the acute care setting, including the law of primacy, pilot in command, crew resource management,...
Source: Health Physics - September 15, 2023 Category: Physics Authors: Michael J Shoemaker Sean M Collins Source Type: research
The value of radiomics model based on ultrasound image features in the differentiation between minimal breast cancer and small benign breast masses
CONCLUSION: The radiomics model based on ultrasound image features has a satisfied predictive ability for small breast masses, and is expected to become a potential tool for the diagnosis of MBC, and it is a zero cost (in terms of patient participation and imaging time).PMID:37712556 | DOI:10.1002/jcu.23556
Source: Clinical Lung Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Shuyi Lyu Meiwu Zhang Baisong Zhang Jiazhen Zhu Libo Gao Yuqin Qiu Liu Yang Yan Zhang Source Type: research
Cognitive-exercise dual-task intervention ameliorates cognitive decline in natural aging rats via inhibiting the promotion of LncRNA NEAT1/miR-124-3p on caveolin-1-PI3K/Akt/GSK3 β Pathway
This study aimed to investigate the effects of CEDI and the role of regulation of the lncRNA NEAT1/miR-124-3p on the caveolin-1-PI3K/Akt/GSK3β pathway in CEDI improving cognitive function. Forty 18-month-old natural aging rats were randomly assigned to four groups: exercise training group, cognitive training group, CEDI group, and aging control group, and underwent 12 weeks of intervention. A novel object recognition test was performed to determine the cognitive function, and the hippocampus was separated three days after the behavioral tests for further molecular detection. In an in vitro study, the mouse hippocampal neu...
Source: Cell Research - September 15, 2023 Category: Cytology Authors: Tiancong Li Xue Tao Ruifeng Sun Conglin Han Xiaoling Li Ziman Zhu Wenshan Li Peiling Huang Weijun Gong Source Type: research
Cardiomyocyte and endothelial cells play distinct roles in the tumor necrosis factor (TNF)-dependent atrial responses and increased atrial fibrillation vulnerability induced by endurance exercise training in mice
CONCLUSIONS: Our findings demonstrate that adverse atrial remodeling and AF vulnerability induced by intense exercise requires TNF in atrial cardiomyocytes whereas the impact of endothelial-derived TNF is limited to hypertrophy modulation. The implications of the cell autonomous effects of TNF and crosstalk between cells in the atria are discussed.TRANSLATIONAL PERSPECTIVE: Endurance sport is associated with atrial fibrillation (AF) and mouse models show intense exercise training promotes atrial hypertrophy, fibrosis, inflammation, and AF vulnerability, which requires the mechanosensitive inflammatory cytokine tumor necros...
Source: Cell Research - September 15, 2023 Category: Cytology Authors: Robert Lakin Nazari Polidovitch Sibao Yang Mihir Parikh Xueyan Liu Ryan Debi Xiaodong Gao Wenliang Chen Camilo Guzman Simona Yakobov Farzad Izaddoustdar Marianne Wauchop Qian Lei Weimin Xu Sergei A Nedospasov Vincent M Christoffels Peter H Backx Source Type: research
A web-based prediction model for long-term cancer-specific survival of middle-aged patients with early-stage gastric cancer: a multi-institutional retrospective study
CONCLUSION: This study developed and validated a new nomogram to predict CSS in middle-aged patients with EGC. The prediction model has unique and practical value and can help doctors carry out individualized treatment and judge prognosis.PMID:37712958 | DOI:10.1007/s00432-023-05405-7
Source: Pain Physician - September 15, 2023 Category: Anesthesiology Authors: Simeng Zhang Longbo Zheng Yuxia Zhang Yuan Gao Lei Liu Zinian Jiang Liang Wang Zheng Ma Jinhui Wu Jiansheng Chen Yun Lu Dongsheng Wang Source Type: research
The Anesthesiology Physician-Scientist Pipeline: Current Status and Recommendations for Future Growth-An Initiative of the Anesthesia Research Council
Anesth Analg. 2023 Oct 1;137(4):728-742. doi: 10.1213/ANE.0000000000006520. Epub 2023 Sep 5.ABSTRACTThe limited number and diversity of resident physicians pursuing careers as physician-scientists in medicine has been a concern for many decades. The Anesthesia Research Council aimed to address the status of the anesthesiology physician-scientist pipeline, benchmarked against other medical specialties, and to develop strategic recommendations to sustain and expand the number and diversity of anesthesiology physician-scientists. The working group analyzed data from the Association of American Medical Colleges and the Nationa...
Source: Pain Physician - September 15, 2023 Category: Anesthesiology Authors: Charles W Emala Vivianne L Tawfik Meghan B Lane-Fall Paloma Toledo Cynthia A Wong Monica S Vavilala Lee A Fleisher Margaret Wood Source Type: research
