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Procedure: Liver Transplant

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Total 21872 results found since Jan 2013.

New‐onset diabetes mellitus after pediatric liver transplantation
Abstract In the first five yr after liver transplant, approximately one in 10 pediatric recipients will develop NODAT. Factors associated with higher risk for NODAT have been difficult to identify due to lack of uniformity in reporting and data collection. Limited studies have reported higher risk in those who are at an older age at transplant, those with high‐risk ethnic backgrounds, and in those with particular underlying conditions, such as CF and primary sclerosing cholangitis. Immunosuppressive medications, including tacrolimus, cyclosporine A, GC, and sirolimus, have been implicated as contributing to NODAT, to va...
Source: Pediatric Transplantation - May 29, 2015 Category: Transplant Surgery Authors: Molly O. Regelmann, Marina Goldis, Ronen Arnon Tags: Review Article Source Type: research

Intensive care management of patients with liver disease: proceedings of a single-topic conference sponsored by the Brazilian Society of Hepatology
ABSTRACT Survival rates of critically ill patients with liver disease has sharply increased in recent years due to several improvements in the management of decompensated cirrhosis and acute liver failure. This is ascribed to the incorporation of evidence-based strategies from clinical trials aiming to reduce mortality. In order to discuss the cutting-edge evidence regarding critical care of patients with liver disease, a joint single topic conference was recently sponsored by the Brazilian Society of Hepatology in cooperation with the Brazilian Society of Intensive Care Medicine and the Brazilian Association for Organ Tra...
Source: Arquivos de Gastroenterologia - March 9, 2016 Category: Gastroenterology Source Type: research

Research Articles Individualizing liver transplant immunosuppression using a phenotypic personalized medicine platform
Posttransplant immunosuppressive drugs such as tacrolimus have narrow therapeutic ranges. Inter- and intraindividual variability in dosing requirements conventionally use physician-guided titrated drug administration, which results in frequent deviations from the target trough ranges, particularly during the critical postoperative phase. There is a clear need for personalized management of posttransplant regimens to prevent adverse events and allow the patient to be discharged sooner. We have developed the parabolic personalized dosing (PPD) platform, which is a surface represented by a second-order algebraic equation with...
Source: Science Translational Medicine - April 5, 2016 Category: Biomedical Science Authors: Zarrinpar, A., Lee, D.-K., Silva, A., Datta, N., Kee, T., Eriksen, C., Weigle, K., Agopian, V., Kaldas, F., Farmer, D., Wang, S. E., Busuttil, R., Ho, C.-M., Ho, D. Tags: Research Articles Source Type: research

Automated deep learning-based quantification of baseline imaging PET metrics on FDG PET/CT images of pediatric lymphoma patients
Conclusions: An automated method using an ensemble of multi-resolution pathway 3D CNNs was able to quantify potentially prognostic imaging biomarkers of lymphoma on baseline FDG PET/CT images with excellent agreement to reference physician PET segmentation. Acknowledgement: This work was partially supported by GE Healthcare. We would also like to thank IROC-Rhode Island for their assistance with image transfers.
Source: Journal of Nuclear Medicine - May 14, 2020 Category: Nuclear Medicine Authors: Weisman, A., Kim, J., Lee, I., McCarten, K., Kessel, S., Schwartz, C., Kelly, K., Jeraj, R., Cho, S., Bradshaw, T. Tags: Artificial Intelligence for Detection, Segmentation and Quantification Source Type: research

Parameters affecting outcome of paediatric cardiomyopathies in the intensive care unit: experience of an Egyptian tertiary centre over 7 years.
Conclusions Conclusions The occurrence of hypotension, abnormally high liver enzymes, the need for mechanical ventilation and the need for multiple inotropic drugs were found to be statistically significant predictors of mortality, while age, sex, fractional shortening, ejection fraction, presence of mitral regurgitation, mural thrombus, electrolyte disturbance and arrhythmias did not predict or affect patients' outcomes. PMID: 33048664 [PubMed - in process]
Source: Libyan Journal of Medicine - October 15, 2020 Category: General Medicine Tags: Libyan J Med Source Type: research

Thoracoscopic Approach for Repair of Diaphragmatic Hernia Occurring After Pediatric Liver Transplant
We report our experience of minimally invasive thoracoscopic approach for repair of DH occurring after LT in pediatric recipients. From April 2010 to December 2014, 7 cases of DH were identified in pediatric LT recipient in Samsung Medical Center. Thoracoscopic repair was attempted in 3 patients. Patients’ medical records were retrospectively reviewed. Case 1 was a 12-month-old boy, having received deceased donor LT for biliary atresia (BA) 5 months ago. He presented with dyspnea and left-sided DH was detected. Thoracoscopic repair was successfully done and the boy was discharged at postoperative day 7. Case 2 was a 13-m...
Source: Medicine - August 1, 2015 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Pediatric Intestinal Rehabilitation and Transplantation Registry: Initial Report from a European Collaborative Registry
Conclusion We present the web-based registry PIRAT and the first results of patients with IF registered from two European Centers. PIRAT could give the opportunity to create a dedicated international network (IF-net) to standardize, improve, and spread the therapeutic paths for the rare and heterogeneous condition of SBS-related IF. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: European Journal of Pediatric Surgery - August 24, 2017 Category: Surgery Authors: Totonelli, Giorgia Tambucci, Roberto Boscarelli, Alessandro Hermans, Dominique Dall'Oglio, Luigi Diamanti, Antonella d'Aische, Aloys du Bois Pakarinen, Mikko Reding, Raymond Morini, Francesco Bagolan, Pietro Fusaro, Fabio Tags: Original Article Source Type: research

Near ‐infrared spectroscopy might be a useful tool for predicting the risk of vascular complications after pediatric liver transplants: Two case reports
Abstract In patients that have undergone liver transplants, a postoperative reduction in the blood flow of the liver graft represents a critical complication. We recently encountered an interesting phenomenon; that is, we found that the rSO2 level of the liver graft, as measured by NIRS, drops in patients that subsequently require an emergency liver biopsy. An 8‐month‐old female and an 8‐month‐old male underwent living donor liver transplants for biliary atresia. In both cases, a reduction in rSO2 was detected before an emergency liver biopsy was required. As a result of biopsy examinations, both patients were diag...
Source: Pediatric Transplantation - November 21, 2017 Category: Transplant Surgery Authors: Juntaro Shiba, Masaaki Satoh, Koki Taira, Yasunori Niwa, Soichiro Inoue, Koichi Mizuta, Mamoru Takeuchi Tags: CASE REPORT Source Type: research

Adult liver transplantation using pediatric donor livers after cardiac or brain death: A report of three cases.
Authors: Ding L, Deng L, Li X, Xu Z Abstract The present study reports on the experience at Jiangxi Provincial People's Hospital (Nanchang, China) with liver transplantation in adults using pediatric donor livers, including indications, technique and results. A total of three cases of liver transplantation performed between April 2008 and May 2016 were retrospectively reviewed. Liver procurement and trimming, recipient selection, surgical tips, prevention and treatment of small-for-size syndrome, selection of immunosuppressive regimens, prevention and treatment of vascular complications and anticoagulant therapy we...
Source: Experimental and Therapeutic Medicine - September 23, 2020 Category: General Medicine Tags: Exp Ther Med Source Type: research

Health Equity and Social Determinants of Health in Pediatric Gastroenterology
This article emphasizes pediatric populations and some of the existing SDH and health care disparities seen in pediatric gastroenterology. We specifically review inflammatory bowel disease, endoscopy, bariatric surgery, and liver transplantation. We also examine the burgeoning role of telehealth that has become commonplace since the coronavirus disease 2019 era.
Source: Pediatric Clinics of North America - November 2, 2021 Category: Pediatrics Authors: Rhea Daniel, Jennifer Jimenez, Harpreet Pall Source Type: research

Biliary complications in pediatric liver transplantation: findings of percutaneous transhepatic cholangiography in a large single-center cohort
ConclusionA wide spectrum of biliary complications can occur after pediatric orthotopic liver transplantation. In this large single-center experience, we highlight the value of percutaneous transhepatic cholangiography in their diagnosis and management. Percutaneous treatments in pediatric patients are safe and effective, providing resolution or serving as a bridge to surgery, including re-transplantation.
Source: Pediatric Radiology - February 2, 2022 Category: Radiology Source Type: research

Proceedings of the European Society for Pediatric Gastroenterology, Hepatology and Nutrition Monothematic Conference, 2020: “Acute Liver Failure in Children”: Treatment and Directions for Future Research
Conclusions: The current report summarizes the current insights in medical treatment of pediatric ALF and the directions for future research.
Source: Journal of Pediatric Gastroenterology and Nutrition - March 1, 2022 Category: Gastroenterology Tags: Meeting Proceedings: Hepatology Source Type: research

Management of acute liver failure in infants and children: consensus statement of the pediatric gastroenterology chapter, Indian academy of pediatrics.
Abstract PROCESS: Selected members were requested to prepare guidelines on specific issues, which were reviewed by two other members. These guidelines were then incorporated into a draft statement, which was circulated to all members. On 17th December 2011, Kunwar Viren Oswal round table conference was organized by the Apollo Center for Advanced Pediatrics, Indraprastha Apollo Hospital, New Delhi and the Sub-specialty Chapter of Pediatric Gastroenterology, Indian Academy of Pediatrics. Presentations, ensuing discussions, and opinions expressed by the participants were incorporated into the final draft. Objectives:...
Source: Indian Pediatrics - May 8, 2013 Category: Pediatrics Authors: Pediatric Gastroenterology Chapter of Indian Academy of Pediatrics, Bhatia V, Bavdekar A, Yachha SK Tags: Indian Pediatr Source Type: research

Peripheral blood biomarkers for the characterization of alloimmune reactivity after pediatric liver transplantation
Abstract Individualization of immunosuppressive medications is an important objective in transplantation medicine. Reliable biomarkers to distinguish between patients dependent from intensive immunosuppressive therapy and those where therapy can be minimized among pediatric transplant recipients receiving immunosuppressive medications are still not established. We evaluated the potential of cross‐sectional quantification of regulatory T cells, lymphocyte subsets, and cytokine concentrations as biomarkers in 60 pediatric liver transplant recipients with AR, CR, or normal graft function and in 11 non‐transplanted patient...
Source: Pediatric Transplantation - October 6, 2013 Category: Transplant Surgery Authors: Andrea Briem‐Richter, Alexander Leuschner, Thorsten Krieger, Enke Grabhorn, Lutz Fischer, Bjoern Nashan, Friedrich Haag, Rainer Ganschow Tags: Original Article Source Type: research

Changing definitions of successful outcomes in pediatric liver transplantation
In conclusion, this review outlines the myriad issues around pediatric transplantation that can be addressed so that the transplant recipient may experience a ‘normal’ quality of life.
Source: Current Opinion in Organ Transplantation - October 1, 2014 Category: Surgery Tags: PEDIATRIC TRANSPLANTATION: Edited by Yuri Genyk Source Type: research