Robotic anatomical resection of liver segment 4 with glissonian approach and selective hepatic artery clamping
CONCLUSION: Considering the low quality of the studies included in the SRs, pharmacological treatment with antispasmodics and antidepressants seems to be beneficial for patients with IBS. Among non-pharmacological interventions, psychological interventions seem to be beneficial. However, further clinical trials are recommended with greater methodological rigor to prove these findings.RESUMO CONTEXTO: A s índrome do intestino irritável (SII) é um distúrbio gastrointestinal complexo, cujo entendimento é relativamente incerto e a decisão de orientação do tratamento ainda representa um desafio. OBJETIVO: Identific...
Source: Arquivos de Gastroenterologia - April 23, 2021 Category: Gastroenterology Source Type: research
Interventions for the treatment of irritable bowel syndrome: a review of cochrane systematic reviews
CONCLUSION: Considering the low quality of the studies included in the SRs, pharmacological treatment with antispasmodics and antidepressants seems to be beneficial for patients with IBS. Among non-pharmacological interventions, psychological interventions seem to be beneficial. However, further clinical trials are recommended with greater methodological rigor to prove these findings.RESUMO CONTEXTO: A s índrome do intestino irritável (SII) é um distúrbio gastrointestinal complexo, cujo entendimento é relativamente incerto e a decisão de orientação do tratamento ainda representa um desafio. OBJETIVO: Identific...
Source: Arquivos de Gastroenterologia - April 23, 2021 Category: Gastroenterology Source Type: research
Helicobacter pylori and colorectal neoplasms: a concise review
ABSTRACT Helicobacter pylori is the main etiological agent of all malignant tumors caused by an infectious disease. It is a major, at times dominant, factor in the pathogenesis of a large spectrum of diseases such as acute and chronic gastritis, gastric and duodenal ulcers, gastric carcinoma, and lymphoma. Epidemiological and experimental studies suggest that H. pylori chronic infection may be related to different extragastric diseases, including colorectal neoplasms. This concise review aims to explore the association of H. pylori infection with colorectal cancer and adenoma, including the recent epidemiological findings,...
Source: Arquivos de Gastroenterologia - April 23, 2021 Category: Gastroenterology Source Type: research
Correlation between trough levels of infliximab and postoperative endoscopic recurrence in crohn’s disease patients submitted to ileocolonic resections: a systematic review
CONCLUSION: Low levels of IFX and the presence of antibodies to the drug were directly associated with increased PER rates in patients with CD, who underwent ileocolonic resections. Controlled and randomized clinical trials with adequate methodological quality are warranted to confirm the conclusions from this systematic review.RESUMO CONTEXTO: As taxas de recorr ência endoscópica pós-operatória em pacientes com doença de Crohn (DC) são significativas. A terapia anti-TNF é cada vez mais usada no cenário pós-operatório, apesar da escassez de dados na literatura sobre dosagem de níveis séricos e anticorpos da ...
Source: Arquivos de Gastroenterologia - April 23, 2021 Category: Gastroenterology Source Type: research
Esophageal cancer mortality in brazil: a time-series analysis from the global burden of disease study
CONCLUSION: Despite the high mortality rates for esophageal cancer in Brazil, the trend was decreasing, but with regional differences. Mortality was around four times higher in men.RESUMO CONTEXTO - No mundo, cerca de 450.000 novos casos de c âncer de esôfago são diagnosticados a cada ano. OBJETIVO: Avaliar a tendência das taxas de mortalidade por câncer de esôfago no Brasil entre 1990-2017. MÉTODOS: Estudo de série temporal utilizando dados de mortalidade por câncer de esôfago em residentes ≥ 30 anos no Brasil de 1990 a 2017. Os dados foram estimados pelo estudo Global Burden of Disease (GBD) e analisad...
Source: Arquivos de Gastroenterologia - April 23, 2021 Category: Gastroenterology Source Type: research
Impact of aging in the surgical outcomes of gastric cancer patients
CONCLUSION: Patients<55-year-old have less surgical complications. As age progresses, clinical complications and 90-day mortality gradually rise. OS is worse for those above age 72, and D2 lymphadenectomy should be individualized after this age.RESUMO CONTEXTO: Conforme a idade avan ça, se esperam mais morbidades e menor reserva funcional. Entretanto não está claro qual o impacto do envelhecimento nos resultados cirúrgicos do câncer gástrico (CaG). OBJETIVO: O intuito deste estudo é avaliar os resultados cirúrgicos de pacientes com CaG de acordo com o grupo etário. MÉTODOS: Pacientes submetidos a gastrec...
Source: Arquivos de Gastroenterologia - April 23, 2021 Category: Gastroenterology Source Type: research
Long term management of glycogen storage disease type 1b: a brazilian tertiary center experience
CONCLUSION Managing GSD 1b is challenging not only for the chronic and multisystemic nature of this disease, but also for the additional demands related dietary restrictions, use of multiple medications and the need for frequent follow-up visits; furthermore in Brazil, the difficulties are increased in a scenario where we frequently care for patients with unfavorable socioeconomic status and with irregular supply of medications in the public health system.RESUMO CONTEXTO Glicogenose (GSD) tipo 1b é uma doença multissistêmica em que complicações imunológicas e infecciosas estão presentes, além das manifestações...
Source: Arquivos de Gastroenterologia - April 23, 2021 Category: Gastroenterology Source Type: research
Results of immunohistochemistry in the differential diagnosis of early hepatocellular carcinoma and nodules with high-grade dysplasia in patients with cirrhosis
CONCLUSION: Differential diagnosis of dysplastic nodules and HCC by morphological criteria can be challenging. Immunomarkers are useful and should be used for the differential diagnosis between HCC and HGDN.RESUMO CONTEXTO: O carcinoma hepatocelular (CHC) é o câncer primário do fígado mais frequente e a cirrose é considerada uma doença pré-maligna. Nesse contexto, a sequência evolutiva do nódulo displásico de baixo grau e nódulo displásico de alto grau (NDAG) para CHC precoce e CHC avançado tem sido estudada. O diagnóstico diferencial e ntre NDAG e CHC precoce ainda é um desafio, principalmente em biópsi...
Source: Arquivos de Gastroenterologia - April 23, 2021 Category: Gastroenterology Source Type: research
Prevalence and time of development of systemic arterial hypertension in patients after liver transplantation
CONCLUSION: This study shows that the patients evolved to SAH in an average of 9±6.98 months after immunosuppressive drug use. We have also found high prevalence of systemic arterial hypertension (59.64%) in patients after liver transplantation, who used calcineurin inhibit ors, especially when associated with the use of tacrolimus.RESUMO CONTEXTO: O uso de imunossupressores p ós-transplante de fígado (TF) está associado ao desenvolvimento de hipertensão arterial sistêmica (HAS), além de outras alterações da síndrome metabólica. OBJETIVO: Sendo assim, o objetivo deste estudo foi analisar a partir de quando ...
Source: Arquivos de Gastroenterologia - April 23, 2021 Category: Gastroenterology Source Type: research
Sphincterotomy alone versus sphincterotomy and biliary stent placement in the treatment of bile leaks: 10 year experience at a quaternary hospital
CONCLUSION: ERCP remains the first line treatment for bile leaks with no difference between sphincterotomy alone vs sphincterotomy plus stent placement.RESUMO CONTEXTO: Cirurgia hepatobiliar e trauma hep ático são causas frequentes de fístulas biliares, e esta temida complicação pode ser manejada de forma segura através da colangiopancreatografia retrógrada endoscópica (CPRE). O procedimento consiste em esfincterotomia isolada, passagem de prótese biliar ou combinação das duas técnicas, porém a forma ideal permanece incerta. OBJETIVO: O objetivo desse estudo é comparar a realização de esfincterotomia i...
Source: Arquivos de Gastroenterologia - April 23, 2021 Category: Gastroenterology Source Type: research
Indocyanine green fluorescence imaging in robotic surgery: state of art, tips and tricks in current applications
CONCLUSION: Robotic assisted surgery combined to fluorescence imaging technology represents a logical evolution in image guided surgery and technology familiarity with guided information may represent a wider and safer spectrum of use in surgeons ’ hands.RESUMO CONTEXTO: A imagem fluorescente com verde de indocianina (VI) é uma técnica cirúrgica emergente na cirurgia robótica. OBJETIVO: Este artigo relata princípios e abordagens essenciais da fluorescência intraoperatória para sua prática em cirurgia geral. Nosso grupo descreve possíveis armadilhas e apresenta dicas e truques para treinar cirurgiões, torn...
Source: Arquivos de Gastroenterologia - April 23, 2021 Category: Gastroenterology Source Type: research
Rnam expression and dna methylation of dkk2 gene in colorectal cÂncer
CONCLUSION: DKK2 promoter methylation and DKK2 RNA status appear to be biomarkers of cancer diagnosis but not predictors of prognosis.RESUMO CONTEXTO: O c âncer colorretal é a terceira neoplasia mais comum no mundo. A metilação de alguns genes nas ilhas CpG podem causar silenciamento gênico e estar envolvida no desenvolvimento de câncer. O potencial papel de DKK2 como um biomarcador no diagnóstico precoce de CCR permanece incerto. OBJETIVO: O objetivo do estudo foi avaliar o perfil de metilação e expressão de RNAm do gene DKK2 para identificar preditores potenciais de diagnóstico e prognóstico de CCR. MÉ...
Source: Arquivos de Gastroenterologia - April 23, 2021 Category: Gastroenterology Source Type: research
Body iron status indicators and inflammation indicators during inflammatory bowel disease therapy in children and adolescentes
CONCLUSION: In conclusion, there were some contradictions among the different body iron status indicators and inflammation indicators at two and 6 months of treatment with conventio nal and infliximab therapy, however after one year of treatment, as shown by the remission group, all indicators studied, except transferrin, were similar to healthy children and adolescents.RESUMO CONTEXTO: O tratamento de pacientes com doen ça inflamatória intestinal (DII) consiste na indução e manutenção da remissão da doença. Os indicadores do estado corporal do ferro seriam úteis para o diagnóstico da anemia por deficiência d...
Source: Arquivos de Gastroenterologia - April 23, 2021 Category: Gastroenterology Source Type: research
Helicobacter pylori chronic gastritis on patients with premalignant conditions: olga and olgim evaluation and serum biomarkers performance
CONCLUSION: The histological classifications OLGA and OLGIM presented a substantial concordance rate among themselves. Simultaneous use of both histological classification systems increased the identification ’ s rate of high-risk patients. Biomarker analysis was not effective to distinguish low to high risk patients in the studied population. Further studies are needed to validate its use in clinical practice in Brazil.RESUMO CONTEXTO: Gastrite atr ófica crônica por H. pylori constitui lesão pré-maligna e seu estadiamento de acordo com os sistemas OLGA e OLGIM, visa identificar pacientes com maior risco de desenv...
Source: Arquivos de Gastroenterologia - April 23, 2021 Category: Gastroenterology Source Type: research
Inappropriate usage of intravenous proton pump inhibitors and associated factors in a high complexity hospital in brazil
CONCLUSION: There was a high number of inappropriate IV omeprazole prescriptions in the studied hospital, entailing greater costs to the institution and unnecessary risks.RESUMO CONTEXTO: Atualmente, o uso intravenoso (IV) dos inibidores de bomba de pr ótons (IBPs) é indicado em poucas situações, como em casos de hemorragia digestiva alta ou impossibilidade de recebê-los via oral. Há diversos estudos mostrando o uso excessivo desse fármaco, na forma intravenosa, desnecessariamente e acarretando altos custos aos hospitais. OBJETIVO: Avalia r as indicações, posologias, duração do tratamento e custos das presc...
Source: Arquivos de Gastroenterologia - April 23, 2021 Category: Gastroenterology Source Type: research
