Genexpert for abdominal tuberculosis
CONCLUSION: NRS was more sensitive than other indicators in the diagnosis of malnutrition. Patients at risk were older and had lower HEC values, calf circumference, BMI and lymphocyte count. Low lymphocyte count was considered a factor associated with nutritional risk by the NRS.RESUMO CONTEXTO: A desnutri ção está associada a fatores clínicos, incluindo maior tempo de internação, aumento da morbimortalidade e custos hospitalares. OBJETIVO: Investigar a prevalência de desnutrição por diferentes indicadores nutricionais e identificar fatores que contribuem para a...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Predictive parameters to identify incontinent patients amenable for rehabilitation treatment: the muscular synergies evaluation
CONCLUSION: NRS was more sensitive than other indicators in the diagnosis of malnutrition. Patients at risk were older and had lower HEC values, calf circumference, BMI and lymphocyte count. Low lymphocyte count was considered a factor associated with nutritional risk by the NRS.RESUMO CONTEXTO: A desnutri ção está associada a fatores clínicos, incluindo maior tempo de internação, aumento da morbimortalidade e custos hospitalares. OBJETIVO: Investigar a prevalência de desnutrição por diferentes indicadores nutricionais e identificar fatores que contribuem para a...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

ASSOCIATION OF TNF-α-308G>A POLYMORPHISMAND CELIAC DISEASE
CONCLUSION: NRS was more sensitive than other indicators in the diagnosis of malnutrition. Patients at risk were older and had lower HEC values, calf circumference, BMI and lymphocyte count. Low lymphocyte count was considered a factor associated with nutritional risk by the NRS.RESUMO CONTEXTO: A desnutri ção está associada a fatores clínicos, incluindo maior tempo de internação, aumento da morbimortalidade e custos hospitalares. OBJETIVO: Investigar a prevalência de desnutrição por diferentes indicadores nutricionais e identificar fatores que contribuem para a...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Nutritional indicators of malnutrition in hospitalized patients
CONCLUSION: NRS was more sensitive than other indicators in the diagnosis of malnutrition. Patients at risk were older and had lower HEC values, calf circumference, BMI and lymphocyte count. Low lymphocyte count was considered a factor associated with nutritional risk by the NRS.RESUMO CONTEXTO: A desnutri ção está associada a fatores clínicos, incluindo maior tempo de internação, aumento da morbimortalidade e custos hospitalares. OBJETIVO: Investigar a prevalência de desnutrição por diferentes indicadores nutricionais e identificar fatores que contribuem para a...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

New immunization schedule effectiveness against hepatitis b in liver transplantation patients
CONCLUSION: The studies did not find seroconversion superiority between the different immunization schedules (conventional and unconventional). However, since candidates to liver transplantation are usually very vulnerable, results show that super accelerated immunization schedules are possibly recommended for such group of patients; serologic test results will be higher when the immunization schedule is completed in the pre-transplant period.RESUMO CONTEXTO: O transplante de f ígado, apesar de ser um procedimento de elevado risco, está consolidado como recurso terapêutico para cura e melhoria da qualid...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Impact of current diet at the risk of non-alcoholic fatty liver disease (nafld)
ABSTRACT The nonalcoholic fatty liver disease (NAFLD) affects approximately 20%-30% of general population and is even more prevalent among obese individuals. The risk factors mainly associated with NAFLD are diseases related to the metabolic syndrome, genetics and environment. In this review, we provide a literature compilation evaluating the evidence behind dietary components, including calories intake, fat, protein, fibers and carbohydrate, especially fructose which could be a trigger to development and progression of the NAFLD. In fact, it has been demonstrated that diet is an important factor for the development of NAF...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Definition of vitamin d deficiency in schoolchildren: systematic review with meta-analysis
CONCLUSION: The most common definition in the literature of 25(OH)D deficiency in schoolchildren was at levels below 20 ng/mL. No side effects have been reported in studies that used fortification and/or vitamin D supplementation. Daily supplementation is more effective than seasonal supplementation. However, more studies are needed to define what can be considered as optimal levels of 25(OH)D in children.RESUMO CONTEXTO: A defici ência de vitamina D está sendo reconhecida como uma pandemia devido ao volume de pessoas afetadas pela deficiência e o número de doenças geradas ou estimuladas po...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Helicobacter pylori infection and gastric cancer precursor lesions: prevalence and associated factors in a reference laboratory in southeastern brazil
ABSTRACT BACKGROUND: Helicobacter pylori infection is the most important risk factor for gastric atrophy and intestinal metaplasia, both considered gastric cancer precursor lesions. Therefore, the investigation of the occurrence of H. pylori infection, precursor lesions and associated factors guides the adoption of specific strategies for the control this type of cancer. OBJECTIVE: To evaluate the prevalence of H. pylori infection in patients undergoing upper digestive endoscopy, as well as the prevalence of intestinal metaplasia, atrophy and chronic inflammation and their association with H. pylori infection. METHODS: A r...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Risk factors associated with early mortality after percutaneous endoscopic gastrostomy in patients at a tertiary care center in brazil: a retrospective single-center survival study
CONCLUSION: In patients who had been subjected to the PEG procedure for long-term nutrition, low haemoglobin, pre-procedure intensive care unit internment or both are associated with the risk of early mortality.RESUMO CONTEXTO: A gastrostomia endosc ópica percutânea (GEP) é o principal método aceito para a alimentação por sonda em um longo período. OBJETIVO: Investigar os fatores de risco associados à mortalidade precoce após a realização de GEP. MÉTODOS: Análise retrospectiva de sobrevida em um centro terciário em Recife, Bra ...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Quercetin supplementation prevents changes in the serotonin and caspase-3 immunoreactive cells of the jejunum of diabetic rats
CONCLUSION: These results suggest that quercetin supplementation mostly improved the serotonergic function affected by diabetes maybe due to antioxidant and anti-inflammatory properties of quercetin.RESUMO CONTEXTO: A serotonina (5-HT) est á presente nas células epiteliais enterocromafins (CE), nos mastócitos da lâmina própria e nos neurônios entéricos. A 5-HT está envolvida na regulação da motilidade, secreção, nocepção intestinal, sistema imunológico e inflamação. Objetivo: Avaliar os efeitos do diabetes e...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Study of lipid biomarkers of patients with polyps and colorectal cÂncer
CONCLUSION: Possible lipid biomarkers were identified among cancer patients compared to control and polyp groups. The polyketide lipid (810.1) was the best biomarker to differentiate the cancer group from control and polyp. We found no difference between the biomarkers in the polyp group in relation to the control.RESUMO CONTEXTO: O c âncer colorretal (CCR) é, mundialmente, uma das principais causas de câncer. Métodos de diagnóstico precoce através de biomarcadores séricos são necessários. O estudo das ômicas, mais recentemente a lipidômica, tem a fin...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Sustained virologic response rate in chronic hepatitis c patients through direct-acting antivirals therapy
CONCLUSION: It was observed that the use of direct-acting antivirals, in comparison to previous therapeutic regimens, increases the sustained virologic response, reaching all patients with mild fibrosis. This study provides information that helps in the hepatitis C treatment by showing that prescribing early treatment for patients without hepatic fibrosis and/or genotype 3 virus could increase therapeutic effectiveness.RESUMO CONTEXTO: O manejo e a possibilidade de erradica ção da infecção pelo vírus da hepatite C têm sido muito pesquisados nos últimos anos pela importâ...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Prospective monitoring of drug use: drug-induced liver injury in a primary healthcare center
CONCLUSION: Drug-induced liver injury is rare in primary healthcare units. It also allowed estimating the incidence of hepatotoxicity induced by allopathic medicines which are standardized by public healthcare authorities.RESUMO CONTEXTO: As les ões hepáticas induzidas por drogas (DILI), ainda são mal compreendidas no Brasil devido a dificuldades diagnósticas ou à falta de relatos. OBJETIVO: Avaliar a frequência de eventos adversos relacionados ao uso de medicamentos em uma unidade básica de saúde, em uma cidade do sudoeste baiano . MÉTODOS: Estudo prospectivo r...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Altered esophageal motility during perception of bolus transit in healthy volunteers
CONCLUSION: The perception of swallowed bolus transit through the esophagus in healthy individuals is more frequent with solid than liquid swallows and is associated with changes in proximal esophageal contractions.RESUMO CONTEXTO: A percep ção do trânsito de bolo deglutido através do esôfago torácico pode ser consequência de alterações anatômicas ou funcionais do esôfago. OBJETIVO: Avaliar, em voluntários saudáveis, se a deglutição com percepção do trânsito do bolo pelo esôfago está associad...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Lymphocyte count and platelet volume predicts postoperative complications in esophagectomy for cancer: a cohort study
CONCLUSION: This is the first study to assess the relationship between peripheral blood count variables changes during neoadjuvant chemoradiotherapy using a platinum- and taxane-based regimen followed by curative intent esophagectomy for cancer in predicting postoperative complications. The platelet volume prior to surgery is related to postoperative complications and the lymphocyte count change prior to surgery predicts severe postoperative complications in the setting of trimodal therapy for esophageal cancer.RESUMO CONTEXTO: Os biomarcadores obtidos do hemograma completo s ão fatores prognósticos a longo p...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Cytotoxic effects of duloxetine on mkn45 and nih3t3 cell lines and genotoxic effects on human peripheral blood lymphocytes
CONCLUSION: Although, in this study, duloxetine had less genotoxicity than cisplatin in concentrations under 200 μ M and showed cytotoxic effects as well, due to its IC50, it cannot be considered as a better choice for gastric cancer therapies with respect to cisplatin as a common anticancer drug.RESUMO CONTEXTO: O c âncer gástrico é a segunda principal causa de morte relacionada ao câncer globalmente. Infelizmente, a taxa de sobrevivência dos pacientes com câncer gástrico que se submeteram à quimioterapia após a cirurgia, tem sido inferior à metade. Al&e...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

METALLOTHIONEIN-2A (RS1610216&RS28366003) GENE POLYMORPHISMS AND THE RISK OF STOMACH ADENOCARCINOMA
CONCLUSION: The MT-2A gene polymorphism was associated with the risk of adenocarcinoma in the Iranian population.RESUMO CONTEXTO: O c âncer gástrico é a quarta causa mais comum de câncer em todo o mundo. Também em contraste com os enormes avanços na cura, a chance de viver é muito baixa, mesmo em casos de cirurgia. Ter uma predisposição genética desempenha um papel importante no desenvolvimento do câncer. A associação entre polimorfismos do gene metalotioneína-2A e o risco de adenocarcinoma tem sido amplamente estudada, mas h&aac...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Antibiotic resistance surveillance of helicobacter pylori at the biobÍo region (chile) in a decade
ABSTRACT BACKGROUND: Helicobacter pylori infection in Chile remains as a public and private health-care system ’ s challenge, with a prevalence of the infection over 70%. Nowadays, antibiotic treatment of the infection is mandatory to prevent the arising of severe associated diseases but failures in the eradication therapy mainly due to clarithromycin resistance has been observed worldwide and first line eradication therapy seems to be not effective anymore in several geographical areas. Thus, health-care systems are committed to maintain an epidemiological surveillance upon the evolution of the antibiotic resistance...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Sarcopenia and severity of non-alcoholic fatty liver disease
ABSTRACT BACKGROUND: Non-alcoholic fatty liver disease is characterized by deposition of lipids in the hepatic parenchyma exceeding 5% of liver weight in the absence of other conditions, such as viral or alcoholic hepatitis and metabolic disease. Non-alcoholic fatty liver disease is the most common form of chronic liver disease in several countries. In addition to liver complications, recent studies have shown a relation between liver fat and sarcopenia. OBJECTIVE: Determine the association between sarcopenia and the severity of non-alcoholic hepatic steatosis diagnosed by abdominal ultrasonography. METHODS: A clinical, cr...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Physical activity in daily life, exercise capacity and quality of life in patients with crohn’s disease on infliximab-induced remission: a preliminary study
CONCLUSION: Patients with Crohn ’ s disease on infliximab-induced remission, despite to more time spent lying down, they have the same level of physical activity in daily life and exercise capacity min compared with the controls.RESUMO CONTEXTO: A atividade f ísica na vida diária e a capacidade de exercício não tem sido avaliada em pacientes com doença de Crohn. OBJETIVO: Avaliar a atividade física na vida diária, capacidade de exercício, qualidade de vida e distúrbios de humor em pacientes com doença de Crohn moderada-grave em remissão indu...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Profile of hcv genotypes and hiv-subtypes among hiv-coinfected patients in southern brazil
CONCLUSION: In the present study, a higher frequency of subtype B of HIV and HCV-1 were found in HIV-coinfected patients. Further larger-scale and long-term studies are needed to better understand the effect of HCV genotypes in HIV-infected patients.RESUMO CONTEXTO: Os v írus das hepatites B e C (VHB e VHC) são os causadores das duas infecções mais comuns entre os pacientes infectados pelo vírus da imunodeficiência humana (HIV). OBJETIVO: Identificar a frequência dos subtipos do HIV e genótipos de VHC em pacientes coinfectados com HIV. MÉTODOS: Estudo t ransversa...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Mental disorders and quality of life in patients awaiting liver transplantation
CONCLUSION: A high-prevalence of psychiatric disorders was found among all clinical conditions most associated with indication for liver transplantation. Attention is drawn to the absence of patients with psychotic disorders, which suggests that transplantation may not have been indicated for this group of patients. For these reasons, professionals caring for liver transplant candidates should be highly vigilant for the presence of mental disorders, regardless of the etiology of liver disease. Specialized care is recommended to minimize the early exclusion of patients with no other therapeutic possibilities, as well as car...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Hepatoprotective efficacy of methanolic extract of indigofera suffruticosa (mill) on paracetamol-induced liver damage in mice
CONCLUSION: This study suggests that MEIS has hepatoprotective activity and high antioxidant potential.RESUMO CONTEXTO: Indigofera suffruticosa Mill (Fabaceae) é abundante no nordeste do Brasil e popularmente utilizada no tratamento de processos infecciosos e inflamatórios. Várias propriedades biológicas, como anti-inflamatório, anticâncer, antitumoral, hepatoprotetor e baixa toxicidade, são relatadas para esta planta. OBJETIVO: Este estudo invest igou a atividade hepatoprotetora e o efeito antioxidante do extrato metanólico de folhas de I. suffruticosa (MEIS) em camun...
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

An inevitable consequence
(Source: Arquivos de Gastroenterologia)
Source: Arquivos de Gastroenterologia - November 29, 2019 Category: Gastroenterology Source Type: research

Erratum
CONCLUSION: To the best of our knowledge, this is the first meta-analysis summarizing all of the available studies on the association of IL-6 -174G>C and IL-10 -1082A>G polymorphisms with celiac disease. Our results suggest that the IL-6 -174G>C and IL-10 -1082A>G polymorphisms may not be associated with increased risk of celiac disease. Moreover, large and well-designed studies are needed to fully describe the association of IL-6 -174G>C and IL-10 -1082A>G polymorphisms with celiac disease.RESUMO CONTEXTO: H á poucas evidências para sugerir que os IL-6 -174G>C e IL-10 -1082A>G polimorf...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

ASSOCIATIONS OF IL-6 -174G>C AND IL-10 -1082A>G POLYMORPHISMS WITH SUSCEPTIBILITY TO CELIAC DISEASE: EVIDENCE FROM A META-ANALYSIS AND LITERATURE REVIEW
CONCLUSION: To the best of our knowledge, this is the first meta-analysis summarizing all of the available studies on the association of IL-6 -174G>C and IL-10 -1082A>G polymorphisms with celiac disease. Our results suggest that the IL-6 -174G>C and IL-10 -1082A>G polymorphisms may not be associated with increased risk of celiac disease. Moreover, large and well-designed studies are needed to fully describe the association of IL-6 -174G>C and IL-10 -1082A>G polymorphisms with celiac disease.RESUMO CONTEXTO: H á poucas evidências para sugerir que os IL-6 -174G>C e IL-10 -1082A>G polimorf...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Biological therapy penetration for inflammatory bowel disease in latin america: current status and future challenges
CONCLUSION: Penetration of anti-TNF agents in Latin America is comparable to the rest of the world in CD, but lower in UC. With the increase in the incidence and prevalence of IBD, specific strategies to increase access to anti-TNF agents in UC and new biological agents overall are warranted.RESUMO CONTEXTO: A introdu ção dos agentes anti-TNF representou um marco no tratamento da doença de Crohn (DC) e da recocolite ulcerativa (RCU), com maior eficácia e segurança quando comparado ao tratamento convencional. No entanto, ainda existem desafios significativos na América Latina para f...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Vedolizumab in the management of inflammatory bowel diseases: a brazilian observational multicentric study
CONCLUSION: Vedolizumab was effective in induction and maintenance of clinical response and remission in CD and UC, with no new safety signs.RESUMO CONTEXTO: H á escassez de dados sobre a eficácia e segurança do vedolizumabe nas doenças inflamatórias intestinais na América Latina. OBJETIVO: Descrever a primeira experiência observacional de mundo real com vedolizumabe em pacientes latino-americanos com doenças inflamatórias intestinais. MÉTODOS : Estudo retrospectivo multicêntrico observacional de pacientes com doença de Crohn (DC) e retocolit...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Analysis of lactose intolerance in students with suggestive symptoms of irritable bowel syndrome
ABSTRACT BACKGROUND: Irritable bowel syndrome is a clinical condition presenting pain, distension and abdominal fullness, diarrhea, constipation, and other symptoms. It generates significant impacts on the quality of life of those affected. The pathophysiology is uncertain, but the role of various food types has been established in bowel sensitivity and its clinical manifestations. Carbohydrate intolerance, particularly to lactose, generates similar and sometimes indistinguishable symptoms from irritable bowel syndrome, and in clinical practice is both a frequent and underdiagnosed condition. Carbohydrate intolerance is re...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Liver transplantation for bile duct injury after cholecystectomy
CONCLUSION: Although the liver transplantation is an extreme treatment for an initially benign disease, it has its well-defined indications in treatment of bile duct injuries after cholecystectomy, either in acute or chronic scenario.RESUMO CONTEXTO: A les ão da via biliar é uma complicação que pode ameaçar a vida e que requer manejo adequado para prevenir o aparecimento de desfechos negativos. Os pacientes podem apresentar episódios repetidos de colangite, cirrose biliar secundária, doença hepática terminal e até mesmo morte. OBJETIVO: Av aliar a experi...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Additional abdominal measurements are a useful tool to evaluate body composition in obese women
CONCLUSION: The results demonstrated a robust correlation between the sum of the three WC measurements and total and trunk DXA in obese women suggesting that such m easurements may be a good indicator of body and trunk fat in women, actually superior to BIA results. The use of these three measurements may be an alternative for the assessment of body and trunk fat, in those cases in which the body shape due to adipose tissue trunk accumulation makes accurate cla ssical measurement (WC1) difficult.RESUMO CONTEXTO: O ac úmulo de tecido adiposo excessivo no ganho de peso se dá em maior proporção no ...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Clinical utility of risk scores in variceal bleeding
This study aims to compare probability of these scores in predicting various outcomes in same population. OBJECTIVE: This study aims to compare probability of these scores in predicting various outcomes in same population. To study characteristics and validate AIMS65, Rockall, Glasgow Blatchford score(GBS), Progetto Nazionale Emorragia Digestiva (PNED) score in variceal Upper Gastrointestinal Bleed (UGIB) patients for predicting various outcomes in our population. METHODS: Three hundred subjects with UGIB were screened prospectively. Of these 141 patients with variceal bleeding were assessed with clinical, blood investigat...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Different scoring systems in acute alcoholic pancreatitis: which one to follow? an ongoing dilema
CONCLUSION: APACHE II emerged as most reliable scori ng system followed by BISAP and Ranson in management of the patients with acute pancreatitis. But in constraints of time and resources, even BISAP score with its significant negative predictive values served as a valuable tool for assessing and managing these patients.RESUMO CONTEXTO: A pancreatite aguda é uma desordem comum na prática médica. Nos últimos tempos, sua gestão mudou drasticamente com a maioria das decisões tomadas baseadas na gravidade da doença, como administração de antibióticos intrave...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Increased risk of synchronous colorectal lesions in patients referred for endoscopic mucosal resection of lateral spreading tumors
CONCLUSION: We found a high prevalence of synchronous lesions among patients with a large colorectal lateral spreading tumor. This risk seems to be increased if index lesions are serrated adenomas.DESCRITORES CONTEXTO: A ressec ção endoscópica de mucosa é uma das alternativas terapêuticas frequentes para grandes tumores colorretais de propagação lateral. Há poucos dados sobre a prevalência de lesões síncronas nesses pacientes. OBJETIVO: Descrever a prevalência de lesões colorretais síncronas em pacientes en caminhados para ressec...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

A study of metabolic parameters in non diabetic patients with non alcoholic fatty liver disease - importance of dyslipidemia
CONCLUSION: In nondiabetic teetotallers dyslipidemias are the prime contributors to the development of NAFLD.RESUMO CONTEXTO: Os fatores de risco metab ólicos da doença hepática gordurosa não alcoólica (DHGNA) em abstêmios não diabéticos, que constituem um grupo distinto, não são bem definidos. OBJETIVO: Identificar os fatores de risco metabólicos da DHGNA em indivíduos não diabéticos e que não consumam álcool. MÉTODOS: Em um e studo transversal, o efeito dos parâmetros metabólicos (IMC, n&iacu...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Gender, age, endoscopic findings, urease and helicobacter pylori: all uncorrelated within a sample of a high gastric cancer prevalence population in amazon
CONCLUSION: The authors hypothesize that observed risk factors associated to gastric cancer might be lesser synergistic than is usually expected.RESUMO CONTEXTO: É amplamente assumido que gênero, idade, gastrite e Helicobacter pylori , todos têm algum grau de correlação e, portanto, podem sinergicamente levar ao desenvolvimento de câncer gástrico. OBJETIVO: Neste estudo transversal, esperamos observar a correlação acima mencionada na análise de pr ontuários de 67 pacientes de ambos os sexos (sexo feminino, n=44), média de idade ± desvio...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Evaluation of psoriasis treatment with esomeprazole - a pilot study
CONCLUSION: The use of esomeprazole for psoriasis resulted in excellent clinical results with a significant reduction of PASI score.RESUMO CONTEXTO: A psor íase é uma doença inflamatória da pele que afeta 1%-3% das populações caucasianas e pode ser persistente, desfigurante e estigmatizante. Inibidores da bomba de prótons (IBP) são potentes bloqueadores da secreção de ácido no estômago. Eles são considerados como os agentes de escolha para o tratamento de doenças ácido-pépticas. No entanto, além dos efeitos...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Evaluation of progression of hepatic fibrosis in a group of patients with non-alcoholic fatty liver disease accompanied for 10 years
CONCLUSION: Despite some limitations of our study, such as the small number of patients, and the use of two different methods of evaluation (biopsy and elastography), the data obtained allow us to conclude that of the 39 evaluated cases, 33% (13) presented progression of fibrosis and the total group of 50 patients, 42% had cirrhosis or died due to liver disease. The presence of NASH on hepatic biopsy did not prove to be, in our study, a predictive of the evolution of hepatic fibrosis in the patients.RESUMO CONTEXTO: A doen ça hepática gordurosa não alcoólica vem sendo diagnosticada com frequ&eci...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Association between fatigue and exercise capacity in patients with chronic liver disease awaiting liver transplantation
CONCLUSION: Fatigue was more prevalent and severe in end stage liver disease patients than in healthy controls. Low 6MST values and high levels of dyspnea were associated with fatigue in this scenario.RESUMO CONTEXTO: A fadiga é uma queixa comum em indivíduos com doença hepática crônica candidatos a transplante hepático. Estudos sobre sua associação com capacidade do exercício são escassos. OBJETIVO: Avaliar a fadiga de pacientes com hepatopia crônica candidatos a transplante hepático comparando com um grupo de indivíduos saudáv...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Pancreaticoduodenectomy with venous resection: an analysis of 30-day morbidity and mortality
CONCLUSION: PD with venous resection for advanced pancreatic neoplasms is a feasible procedure, but associated with high rates of morbidity and mortality; higher ASA e ECOG scores were significantly associated with a higher 30-day mortality.RESUMO CONTEXTO: A duodenopancreatectomia (DP) com ressec ção de estruturas venosas adjacentes à cabeça do pâncreas, mesmo em casos de invasão extensa, tem sido praticada nos últimos anos, mas sua morbidade e mortalidade perioperatórias não são completamente determinadas. OBJETIVO: Descrever os resultados perioperat&oa...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Nonalcoholic fatty liver disease (nafld), more than a liver disease
(Source: Arquivos de Gastroenterologia)
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Update of the brazilian society of hepatology recommendations for diagnosis and management of autoimmune diseases of the liver
ABSTRACT New data concerning the management of autoimmune liver diseases have emerged since the last single-topic meeting sponsored by the Brazilian Society of Hepatology to draw recommendations about the diagnosis and treatment of autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), overlap syndromes of AIH, PBC and PSC and specific complications and topics concerning AIH and cholestatic liver diseases. This manuscript updates those previous recommendations according to the best evidence available in the literature up to now. The same panel of experts that took part in the f...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Recommendations for invasive procedures in patients with diseases of the liver and biliary tract: report of a joint meeting of the brazilian society of hepatology (sbh), brazilian society of digestive endoscopy (sobed) and brazilian society of interventional radiology and endovascular surgery (sobrice)
ABSTRACT Liver and biliary tract diseases are common causes of morbidity and mortality worldwide. Invasive procedures are usually performed in those patients with hepatobiliary diseases for both diagnostic and therapeutic purposes. Defining proper indications and restraints of commonly used techniques is crucial for proper patient selection, maximizing positive results and limiting complications. In 2018, the Brazilian Society of Hepato ­logy (SBH) in cooperation with the Brazilian Society of Interventional Radiology and Endovascular surgery (SOBRICE) and the Brazilian Society of Digestive Endoscopy (SOBED) sponsored a...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

In defense of four decades of esophageal function tests. reply to reaction to articles on high resolution manometry, the length of the lower esophageal sphincter and the diagnosis of gastroesophageal reflux disease
CONCLUSION: Recognizing the historical evolution of GERD management can help care providers to better understand therapeutic options for their patients, as well as focus on unmet needs that deserve further attention. PPIs are still the first choice therapy, with good evidence in favor of their efficacy, despite some safety concerns. However, as with any medical intervention, it is recommended to prescribe PPIs for patients with clear indication, using adequate dosing and monitoring for adverse events.RESUMO CONTEXTO: A doen ça do refluxo gastroesofágico (DRGE) é uma das doenças gastrointestinais...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Reaction to articles on high resolution manometry, the length of the lower esophageal sphincter and the diagnosis of gastroesophageal reflux disease
CONCLUSION: Recognizing the historical evolution of GERD management can help care providers to better understand therapeutic options for their patients, as well as focus on unmet needs that deserve further attention. PPIs are still the first choice therapy, with good evidence in favor of their efficacy, despite some safety concerns. However, as with any medical intervention, it is recommended to prescribe PPIs for patients with clear indication, using adequate dosing and monitoring for adverse events.RESUMO CONTEXTO: A doen ça do refluxo gastroesofágico (DRGE) é uma das doenças gastrointestinais...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Historical perspective of gastroesophageal reflux disease clinical treatment
CONCLUSION: Recognizing the historical evolution of GERD management can help care providers to better understand therapeutic options for their patients, as well as focus on unmet needs that deserve further attention. PPIs are still the first choice therapy, with good evidence in favor of their efficacy, despite some safety concerns. However, as with any medical intervention, it is recommended to prescribe PPIs for patients with clear indication, using adequate dosing and monitoring for adverse events.RESUMO CONTEXTO: A doen ça do refluxo gastroesofágico (DRGE) é uma das doenças gastrointestinais...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Prospective study for validation of a single protocol for the 13c-urea breath test using two different devices in the diagnosis of h. pylori infection
CONCLUSION: Correlation between the two devices was excellent and supports a uniform standardization of UBT.RESUMO CONTEXTO: O teste respirat ório com ureia-marcada com carbono-13 (TR-13C) é o método padrão-ouro para o diagnóstico não invasivo da infecção por H. pylori. Apesar disto, não existe uma uniformização de protocolos para a sua realização, trazendo dificuldades operacionais para laboratórios ou clínicas que operam com equipamentos de fabricantes diferentes. OBJETIVO: Estudo prospectivo e comparativo para valida...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Morphological characterization of colorectal pits using autofluorescence microscopy images
CONCLUSION: These preliminaries outcomes could be considered an advance in two-dimensional pit characterization as the whole image processing, comparing to the conventional procedure, takes a few seconds to quantify and charact erize non-pathological colon pits as well as to estimate early pathological stages of colorectal cancer.RESUMO CONTEXTO: O c âncer colorretal é uma das patologias mais prevalentes. Seu prognóstico é ligado à detenção e ao tratamento precoces. Atualmente o diagnóstico é realizado por análise histológica de biópsias de ...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

N-acetylcysteine and/or ursodeoxycholic acid associated with metformin in non-alcoholic steatohepatitis: an open-label multicenter randomized controlled trial
CONCLUSION: This multicenter study suggests that the association of NAC + MTF could reduce the liver disease activity in patients wi th NASH. These data stimulate further controlled studies with this therapy for these patients.RESUMO CONTEXTO: Atualmente, o tratamento farmacol ógico da doença hepática gordurosa não alcoólica (DHGNA) ainda é limitado e baseia-se no tratamento de condições associadas às comorbidades. O estresse oxidativo e a resistência à insulina são os mecanismos que parecem estar mais envolvidos em sua patogênese. OBJ...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Clinical profile, drug resistance pattern and treatment outcomes of abdominal tuberculosis patients in western india
CONCLUSION: Abdominal tuberculosis with wide spectrum of presentation, can still be managed with early diagnosis and treatment even in patients with sub acute intestinal obstruction. Weight gain or resolving symptoms were considered early markers of treatment response. Patients with stricture can become asymptomatic with medical treatment alone.RESUMO CONTEXTO: A tuberculose abdominal é um problema crescente no mundo em desenvolvimento. OBJETIVO: O objetivo do estudo foi descrever as apresentações clínicas, o padrão de resistência a fármacos e os desfechos de tratamento da tu...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research