Erratum
CONCLUSION: To the best of our knowledge, this is the first meta-analysis summarizing all of the available studies on the association of IL-6 -174G>C and IL-10 -1082A>G polymorphisms with celiac disease. Our results suggest that the IL-6 -174G>C and IL-10 -1082A>G polymorphisms may not be associated with increased risk of celiac disease. Moreover, large and well-designed studies are needed to fully describe the association of IL-6 -174G>C and IL-10 -1082A>G polymorphisms with celiac disease.RESUMO CONTEXTO: H á poucas evidências para sugerir que os IL-6 -174G>C e IL-10 -1082A>G polimorf...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

ASSOCIATIONS OF IL-6 -174G>C AND IL-10 -1082A>G POLYMORPHISMS WITH SUSCEPTIBILITY TO CELIAC DISEASE: EVIDENCE FROM A META-ANALYSIS AND LITERATURE REVIEW
CONCLUSION: To the best of our knowledge, this is the first meta-analysis summarizing all of the available studies on the association of IL-6 -174G>C and IL-10 -1082A>G polymorphisms with celiac disease. Our results suggest that the IL-6 -174G>C and IL-10 -1082A>G polymorphisms may not be associated with increased risk of celiac disease. Moreover, large and well-designed studies are needed to fully describe the association of IL-6 -174G>C and IL-10 -1082A>G polymorphisms with celiac disease.RESUMO CONTEXTO: H á poucas evidências para sugerir que os IL-6 -174G>C e IL-10 -1082A>G polimorf...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Biological therapy penetration for inflammatory bowel disease in latin america: current status and future challenges
CONCLUSION: Penetration of anti-TNF agents in Latin America is comparable to the rest of the world in CD, but lower in UC. With the increase in the incidence and prevalence of IBD, specific strategies to increase access to anti-TNF agents in UC and new biological agents overall are warranted.RESUMO CONTEXTO: A introdu ção dos agentes anti-TNF representou um marco no tratamento da doença de Crohn (DC) e da recocolite ulcerativa (RCU), com maior eficácia e segurança quando comparado ao tratamento convencional. No entanto, ainda existem desafios significativos na América Latina para f...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Vedolizumab in the management of inflammatory bowel diseases: a brazilian observational multicentric study
CONCLUSION: Vedolizumab was effective in induction and maintenance of clinical response and remission in CD and UC, with no new safety signs.RESUMO CONTEXTO: H á escassez de dados sobre a eficácia e segurança do vedolizumabe nas doenças inflamatórias intestinais na América Latina. OBJETIVO: Descrever a primeira experiência observacional de mundo real com vedolizumabe em pacientes latino-americanos com doenças inflamatórias intestinais. MÉTODOS : Estudo retrospectivo multicêntrico observacional de pacientes com doença de Crohn (DC) e retocolit...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Analysis of lactose intolerance in students with suggestive symptoms of irritable bowel syndrome
ABSTRACT BACKGROUND: Irritable bowel syndrome is a clinical condition presenting pain, distension and abdominal fullness, diarrhea, constipation, and other symptoms. It generates significant impacts on the quality of life of those affected. The pathophysiology is uncertain, but the role of various food types has been established in bowel sensitivity and its clinical manifestations. Carbohydrate intolerance, particularly to lactose, generates similar and sometimes indistinguishable symptoms from irritable bowel syndrome, and in clinical practice is both a frequent and underdiagnosed condition. Carbohydrate intolerance is re...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Liver transplantation for bile duct injury after cholecystectomy
CONCLUSION: Although the liver transplantation is an extreme treatment for an initially benign disease, it has its well-defined indications in treatment of bile duct injuries after cholecystectomy, either in acute or chronic scenario.RESUMO CONTEXTO: A les ão da via biliar é uma complicação que pode ameaçar a vida e que requer manejo adequado para prevenir o aparecimento de desfechos negativos. Os pacientes podem apresentar episódios repetidos de colangite, cirrose biliar secundária, doença hepática terminal e até mesmo morte. OBJETIVO: Av aliar a experi...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Additional abdominal measurements are a useful tool to evaluate body composition in obese women
CONCLUSION: The results demonstrated a robust correlation between the sum of the three WC measurements and total and trunk DXA in obese women suggesting that such m easurements may be a good indicator of body and trunk fat in women, actually superior to BIA results. The use of these three measurements may be an alternative for the assessment of body and trunk fat, in those cases in which the body shape due to adipose tissue trunk accumulation makes accurate cla ssical measurement (WC1) difficult.RESUMO CONTEXTO: O ac úmulo de tecido adiposo excessivo no ganho de peso se dá em maior proporção no ...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Clinical utility of risk scores in variceal bleeding
This study aims to compare probability of these scores in predicting various outcomes in same population. OBJECTIVE: This study aims to compare probability of these scores in predicting various outcomes in same population. To study characteristics and validate AIMS65, Rockall, Glasgow Blatchford score(GBS), Progetto Nazionale Emorragia Digestiva (PNED) score in variceal Upper Gastrointestinal Bleed (UGIB) patients for predicting various outcomes in our population. METHODS: Three hundred subjects with UGIB were screened prospectively. Of these 141 patients with variceal bleeding were assessed with clinical, blood investigat...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Different scoring systems in acute alcoholic pancreatitis: which one to follow? an ongoing dilema
CONCLUSION: APACHE II emerged as most reliable scori ng system followed by BISAP and Ranson in management of the patients with acute pancreatitis. But in constraints of time and resources, even BISAP score with its significant negative predictive values served as a valuable tool for assessing and managing these patients.RESUMO CONTEXTO: A pancreatite aguda é uma desordem comum na prática médica. Nos últimos tempos, sua gestão mudou drasticamente com a maioria das decisões tomadas baseadas na gravidade da doença, como administração de antibióticos intrave...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Increased risk of synchronous colorectal lesions in patients referred for endoscopic mucosal resection of lateral spreading tumors
CONCLUSION: We found a high prevalence of synchronous lesions among patients with a large colorectal lateral spreading tumor. This risk seems to be increased if index lesions are serrated adenomas.DESCRITORES CONTEXTO: A ressec ção endoscópica de mucosa é uma das alternativas terapêuticas frequentes para grandes tumores colorretais de propagação lateral. Há poucos dados sobre a prevalência de lesões síncronas nesses pacientes. OBJETIVO: Descrever a prevalência de lesões colorretais síncronas em pacientes en caminhados para ressec...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

A study of metabolic parameters in non diabetic patients with non alcoholic fatty liver disease - importance of dyslipidemia
CONCLUSION: In nondiabetic teetotallers dyslipidemias are the prime contributors to the development of NAFLD.RESUMO CONTEXTO: Os fatores de risco metab ólicos da doença hepática gordurosa não alcoólica (DHGNA) em abstêmios não diabéticos, que constituem um grupo distinto, não são bem definidos. OBJETIVO: Identificar os fatores de risco metabólicos da DHGNA em indivíduos não diabéticos e que não consumam álcool. MÉTODOS: Em um e studo transversal, o efeito dos parâmetros metabólicos (IMC, n&iacu...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Gender, age, endoscopic findings, urease and helicobacter pylori: all uncorrelated within a sample of a high gastric cancer prevalence population in amazon
CONCLUSION: The authors hypothesize that observed risk factors associated to gastric cancer might be lesser synergistic than is usually expected.RESUMO CONTEXTO: É amplamente assumido que gênero, idade, gastrite e Helicobacter pylori , todos têm algum grau de correlação e, portanto, podem sinergicamente levar ao desenvolvimento de câncer gástrico. OBJETIVO: Neste estudo transversal, esperamos observar a correlação acima mencionada na análise de pr ontuários de 67 pacientes de ambos os sexos (sexo feminino, n=44), média de idade ± desvio...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Evaluation of psoriasis treatment with esomeprazole - a pilot study
CONCLUSION: The use of esomeprazole for psoriasis resulted in excellent clinical results with a significant reduction of PASI score.RESUMO CONTEXTO: A psor íase é uma doença inflamatória da pele que afeta 1%-3% das populações caucasianas e pode ser persistente, desfigurante e estigmatizante. Inibidores da bomba de prótons (IBP) são potentes bloqueadores da secreção de ácido no estômago. Eles são considerados como os agentes de escolha para o tratamento de doenças ácido-pépticas. No entanto, além dos efeitos...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Evaluation of progression of hepatic fibrosis in a group of patients with non-alcoholic fatty liver disease accompanied for 10 years
CONCLUSION: Despite some limitations of our study, such as the small number of patients, and the use of two different methods of evaluation (biopsy and elastography), the data obtained allow us to conclude that of the 39 evaluated cases, 33% (13) presented progression of fibrosis and the total group of 50 patients, 42% had cirrhosis or died due to liver disease. The presence of NASH on hepatic biopsy did not prove to be, in our study, a predictive of the evolution of hepatic fibrosis in the patients.RESUMO CONTEXTO: A doen ça hepática gordurosa não alcoólica vem sendo diagnosticada com frequ&eci...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Association between fatigue and exercise capacity in patients with chronic liver disease awaiting liver transplantation
CONCLUSION: Fatigue was more prevalent and severe in end stage liver disease patients than in healthy controls. Low 6MST values and high levels of dyspnea were associated with fatigue in this scenario.RESUMO CONTEXTO: A fadiga é uma queixa comum em indivíduos com doença hepática crônica candidatos a transplante hepático. Estudos sobre sua associação com capacidade do exercício são escassos. OBJETIVO: Avaliar a fadiga de pacientes com hepatopia crônica candidatos a transplante hepático comparando com um grupo de indivíduos saudáv...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Pancreaticoduodenectomy with venous resection: an analysis of 30-day morbidity and mortality
CONCLUSION: PD with venous resection for advanced pancreatic neoplasms is a feasible procedure, but associated with high rates of morbidity and mortality; higher ASA e ECOG scores were significantly associated with a higher 30-day mortality.RESUMO CONTEXTO: A duodenopancreatectomia (DP) com ressec ção de estruturas venosas adjacentes à cabeça do pâncreas, mesmo em casos de invasão extensa, tem sido praticada nos últimos anos, mas sua morbidade e mortalidade perioperatórias não são completamente determinadas. OBJETIVO: Descrever os resultados perioperat&oa...
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Nonalcoholic fatty liver disease (nafld), more than a liver disease
(Source: Arquivos de Gastroenterologia)
Source: Arquivos de Gastroenterologia - October 1, 2019 Category: Gastroenterology Source Type: research

Update of the brazilian society of hepatology recommendations for diagnosis and management of autoimmune diseases of the liver
ABSTRACT New data concerning the management of autoimmune liver diseases have emerged since the last single-topic meeting sponsored by the Brazilian Society of Hepatology to draw recommendations about the diagnosis and treatment of autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), overlap syndromes of AIH, PBC and PSC and specific complications and topics concerning AIH and cholestatic liver diseases. This manuscript updates those previous recommendations according to the best evidence available in the literature up to now. The same panel of experts that took part in the f...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Recommendations for invasive procedures in patients with diseases of the liver and biliary tract: report of a joint meeting of the brazilian society of hepatology (sbh), brazilian society of digestive endoscopy (sobed) and brazilian society of interventional radiology and endovascular surgery (sobrice)
ABSTRACT Liver and biliary tract diseases are common causes of morbidity and mortality worldwide. Invasive procedures are usually performed in those patients with hepatobiliary diseases for both diagnostic and therapeutic purposes. Defining proper indications and restraints of commonly used techniques is crucial for proper patient selection, maximizing positive results and limiting complications. In 2018, the Brazilian Society of Hepato ­logy (SBH) in cooperation with the Brazilian Society of Interventional Radiology and Endovascular surgery (SOBRICE) and the Brazilian Society of Digestive Endoscopy (SOBED) sponsored a...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

In defense of four decades of esophageal function tests. reply to reaction to articles on high resolution manometry, the length of the lower esophageal sphincter and the diagnosis of gastroesophageal reflux disease
CONCLUSION: Recognizing the historical evolution of GERD management can help care providers to better understand therapeutic options for their patients, as well as focus on unmet needs that deserve further attention. PPIs are still the first choice therapy, with good evidence in favor of their efficacy, despite some safety concerns. However, as with any medical intervention, it is recommended to prescribe PPIs for patients with clear indication, using adequate dosing and monitoring for adverse events.RESUMO CONTEXTO: A doen ça do refluxo gastroesofágico (DRGE) é uma das doenças gastrointestinais...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Reaction to articles on high resolution manometry, the length of the lower esophageal sphincter and the diagnosis of gastroesophageal reflux disease
CONCLUSION: Recognizing the historical evolution of GERD management can help care providers to better understand therapeutic options for their patients, as well as focus on unmet needs that deserve further attention. PPIs are still the first choice therapy, with good evidence in favor of their efficacy, despite some safety concerns. However, as with any medical intervention, it is recommended to prescribe PPIs for patients with clear indication, using adequate dosing and monitoring for adverse events.RESUMO CONTEXTO: A doen ça do refluxo gastroesofágico (DRGE) é uma das doenças gastrointestinais...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Historical perspective of gastroesophageal reflux disease clinical treatment
CONCLUSION: Recognizing the historical evolution of GERD management can help care providers to better understand therapeutic options for their patients, as well as focus on unmet needs that deserve further attention. PPIs are still the first choice therapy, with good evidence in favor of their efficacy, despite some safety concerns. However, as with any medical intervention, it is recommended to prescribe PPIs for patients with clear indication, using adequate dosing and monitoring for adverse events.RESUMO CONTEXTO: A doen ça do refluxo gastroesofágico (DRGE) é uma das doenças gastrointestinais...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Prospective study for validation of a single protocol for the 13c-urea breath test using two different devices in the diagnosis of h. pylori infection
CONCLUSION: Correlation between the two devices was excellent and supports a uniform standardization of UBT.RESUMO CONTEXTO: O teste respirat ório com ureia-marcada com carbono-13 (TR-13C) é o método padrão-ouro para o diagnóstico não invasivo da infecção por H. pylori. Apesar disto, não existe uma uniformização de protocolos para a sua realização, trazendo dificuldades operacionais para laboratórios ou clínicas que operam com equipamentos de fabricantes diferentes. OBJETIVO: Estudo prospectivo e comparativo para valida...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Morphological characterization of colorectal pits using autofluorescence microscopy images
CONCLUSION: These preliminaries outcomes could be considered an advance in two-dimensional pit characterization as the whole image processing, comparing to the conventional procedure, takes a few seconds to quantify and charact erize non-pathological colon pits as well as to estimate early pathological stages of colorectal cancer.RESUMO CONTEXTO: O c âncer colorretal é uma das patologias mais prevalentes. Seu prognóstico é ligado à detenção e ao tratamento precoces. Atualmente o diagnóstico é realizado por análise histológica de biópsias de ...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

N-acetylcysteine and/or ursodeoxycholic acid associated with metformin in non-alcoholic steatohepatitis: an open-label multicenter randomized controlled trial
CONCLUSION: This multicenter study suggests that the association of NAC + MTF could reduce the liver disease activity in patients wi th NASH. These data stimulate further controlled studies with this therapy for these patients.RESUMO CONTEXTO: Atualmente, o tratamento farmacol ógico da doença hepática gordurosa não alcoólica (DHGNA) ainda é limitado e baseia-se no tratamento de condições associadas às comorbidades. O estresse oxidativo e a resistência à insulina são os mecanismos que parecem estar mais envolvidos em sua patogênese. OBJ...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Clinical profile, drug resistance pattern and treatment outcomes of abdominal tuberculosis patients in western india
CONCLUSION: Abdominal tuberculosis with wide spectrum of presentation, can still be managed with early diagnosis and treatment even in patients with sub acute intestinal obstruction. Weight gain or resolving symptoms were considered early markers of treatment response. Patients with stricture can become asymptomatic with medical treatment alone.RESUMO CONTEXTO: A tuberculose abdominal é um problema crescente no mundo em desenvolvimento. OBJETIVO: O objetivo do estudo foi descrever as apresentações clínicas, o padrão de resistência a fármacos e os desfechos de tratamento da tu...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Adiponectin, vitamin d and nutritional status in patients with advanced colorectal cancer or during follow-up
CONCLUSION: Among the nutritional status parameters, only the Patient-Generated Subjective Global Assessment score was significantly different between the groups and was an important predictor of survival in patients with advanced colorectal cancer.RESUMO CONTEXTO: Considerando a alta incid ência de óbitos devido ao câncer coloretal (CCR), estudos investigaram variáveis que podem afetar a sobrevida, com objetivo de prolongar a sobrevida. O estado nutricional desses pacientes também pode predizer a sobrevida. OBJETIVO: O objetivo do presente estudo foi avaliar se o índice de mas sa co...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

The cost of adult liver transplantation in a referral center in southern brazil
CONCLUSION: Our results demonstrated that the total cost of LTx is closely related to liver disease severity scores and the development of complications.RESUMO CONTEXTO: O transplante hep ático (TxH) é o principal e definitivo tratamento de casos agudos ou crônicos de doenças hepáticas avançadas ou terminais. Poucos estudos têm avaliado o custo real do TxH categorizado por setores hospitalares. OBJETIVO: Avaliar o custo do TxH categorizado por especialidade da unidade em um centro de referência na região sul do Brasil. MÉTODOS: Analisamos retrospectivamente...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Internal hernia following laparoscopic roux-en-y gastric by-pass: indicative factors for early repair
CONCLUSION: The presence of recurrent abdominal pain is one of the main indicators for the diagnosis of IH after LRYGB. Patients operated at an early stage, even with negative imaging tests for this disease, benefited from rapid and simple procedures without major complications.RESUMO CONTEXTO: H érnia interna (HI) após bypass gástrico em Y de Roux laparoscópico (BGYRL) é uma complicação importante que desafia o cirurgião devido à sua apresentação inespecífica e necessidade de reparo precoce. Um diagnóstico e intervençã...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Cytotoxic effects of aripiprazole on mkn45 and nih3t3 cell lines and genotoxic effects on human peripheral blood lymphocytes
CONCLUSION: Aripiprazole can be a good cytotoxic compound and good candidate for further studies of cancer therapy.RESUMO CONTEXTO: O c âncer gástrico é conhecido como o quarto câncer mais comum. Os tratamentos atuais para o câncer danificaram os tecidos sensíveis do corpo saudável e, em muitos casos, o cancro será recorrente. Portanto, a necessidade de tratamentos que são mais eficazes é desejada. Recentemente, os pesquis adores mudaram sua atenção para os antagonistas antipsicóticos da dopamina para tratar o câncer. As atividade...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Association between endoscopic findings and histopathological confirmation in patients with suspicion of eosinophilic esophagitis
ABSTRACT BACKGROUND: The diagnosis of eosinophilic esophagitis (EoE) is performed by the detection of 15 or more eosinophils per field in an esophageal biopsy sample, but the endoscopic findings alone are not validated for a diagnosis of the disease. OBJECTIVE: To evaluate the association between the endoscopic findings and histopathological diagnosis in patients with suspected EoE in endoscopy. METHODS: A retrospective study of 24 patients with suspicion of EoE during endoscopy was held. The information was collected from databases of Endoscopy and Pathology services of the Hospital Universit ário Walter Cant&iacut...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Hla-drb1 gene polymorphisms in pediatric patients with type 1 autoimmune hepatitis and type 1 autoimmune hepatitis overlap syndrome with autoimmune cholangitis
CONCLUSION: This work demonstrates an association of the main polymorphisms in the HLA-DRB1 gene to AIH with or without cholangitis in a Brazilian sample.RESUMO CONTEXTO: Hepatite autoimune (HAI) é uma doença hepática inflamatória crônica, rara, associada à perda da tolerância imunológica aos auto-antígenos. A susceptibilidade à HAI é parcialmente determinada pela presença de genes relacionados ao antígeno leucocitário humano (HLA), principalmente variantes alélicas do DRB1. OBJETIVO: O objetivo deste estudo foi investiga...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Investigation of enterococcus faecalis population in patients with polyp and colorectal cancer in comparison of healthy individuals
In this study, the mean copy number of Enterococcus faecalis in people with polyps and people with colorectal cancer has been evaluated in comparison with healthy controls. METHODS: In this study, 25 patients with colorectal cancer and 28 patients with intestinal polyps were selected and stool specimens were taken. In addition, 24 healthy individuals were selected as control group. Extraction of bacterial DNA from the stool sample were performed. The molecular methods of PCR for confirmation of standard strain and absolute Real Time PCR (qRT-PCR) method were used to evaluate the number of Enterococcus faecalis in the studi...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Relationship among psychological well-being, resilience and coping with social and clinical features in crohn’s disease patients
ABSTRACT BACKGROUND: Crohn ’ s disease is chronic, requires prolonged treatment, affects the physical and psychosocial health of patients and may alter their routine, quality of life and well-being. Recent studies recommend monitoring the health of these patients considering physical, psychological and psychosocial aspects, because they are directly related to the disease activity. These studies highlight the relevance of patients ’ emotional and behavioral conditions and suggest that the identification of the factors that influence the psychological well-being, resilience and Coping in these patients can favor...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Immunization status of patients with inflammatory bowel disease
CONCLUSION: Although being a specialized service linked to a university hospital, vaccination coverage and patients ’ awareness rates proved to be below the desirable level. Vaccination and recovery of the immunization history is recommended immediately after the diagnosis of IBD, regardless of the use of biological agents. Those findings support the need of implementing hospital guidelines and constantly verifying its application by the multidisciplinary team in specialized services in IBD.RESUMO CONTEXTO: No tratamento de doen ças inflamatórias intestinais (DII) são usados imunossupressores e a...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Are cariogenic bacteria the major risk factor to dental caries in patients with ulcerative colitis?
CONCLUSION: The prevalence of dental caries observed in UC patients was significant and did not seem to be influenced by their eating habits. The high prevalence of Mutans streptococci count may be a major risk factor for dental caries and may be looked as part of the UC dysbiosis. Dental care of UC patients should be planned according with this microbiota variation.RESUMO CONTEXTO: Uma elevada preval ência de cáries dentárias em doentes com retocolite ulcerativa (RCU) tem sido atribuída à dieta e alterações no ambiente salivar. OBJETIVO: Este estudo pretende caracterizar a p...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Does the rheumatoid arthritis affect the enteric nervous system?
CONCLUSION: Despite arthritis resulted in no alterations in the number of nitrergic neurons, the retraction of ileal area and reduction of nitrergic somatic and VIP-IR varicosity areas may suggest a negative impact the disease on the ENS.RESUMO CONTEXTO: Poucos estudos sobre doen ças artríticas têm sido realizados para verificar a presença de neurodegeneração. Diante do aumento do estresse oxidativo e dos efeitos extra-articulares da artrite reumatoide, estudos gastrointestinais devem ser investigados visando uma melhor compreensão dos efeitos sistêmicos da doenç...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Psychological well-being and quality of life in the clinical approach in crohn’s disease
(Source: Arquivos de Gastroenterologia)
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Partial retraction
CONCLUSION: There is no statistical difference between endoscopic ultrasound guided coils plus cyanoacrylate versus conventional cyanoacrylate technique in relation to the incidence of embolism. However, a greater tendency towards embolism was observed in the group treated using the conventional technique. Both techniques have similar efficacy in the obliteration of varices. Given the small sample size of our pilot data, our results are insufficient to prove the clinical benefit of the combined technique, and do not yet justify its use, especially in light of higher cost. Further studies with larger sample size are warrant...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research

Letter to editor about “new index for the diagnosis of liver fibrosis in schistosomiasis mansoni”
CONCLUSION: There is no statistical difference between endoscopic ultrasound guided coils plus cyanoacrylate versus conventional cyanoacrylate technique in relation to the incidence of embolism. However, a greater tendency towards embolism was observed in the group treated using the conventional technique. Both techniques have similar efficacy in the obliteration of varices. Given the small sample size of our pilot data, our results are insufficient to prove the clinical benefit of the combined technique, and do not yet justify its use, especially in light of higher cost. Further studies with larger sample size are warrant...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research

35 years of the classification of rezende: the importance of esophagogram in the context of chagas disease in brazil
CONCLUSION: There is no statistical difference between endoscopic ultrasound guided coils plus cyanoacrylate versus conventional cyanoacrylate technique in relation to the incidence of embolism. However, a greater tendency towards embolism was observed in the group treated using the conventional technique. Both techniques have similar efficacy in the obliteration of varices. Given the small sample size of our pilot data, our results are insufficient to prove the clinical benefit of the combined technique, and do not yet justify its use, especially in light of higher cost. Further studies with larger sample size are warrant...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research

Safety and efficacy of eus-guided coil plus cyanoacrylate versus conventional cyanoacrylate technique in the treatment of gastric varices: a randomized controlled trial
CONCLUSION: There is no statistical difference between endoscopic ultrasound guided coils plus cyanoacrylate versus conventional cyanoacrylate technique in relation to the incidence of embolism. However, a greater tendency towards embolism was observed in the group treated using the conventional technique. Both techniques have similar efficacy in the obliteration of varices. Given the small sample size of our pilot data, our results are insufficient to prove the clinical benefit of the combined technique, and do not yet justify its use, especially in light of higher cost. Further studies with larger sample size are warrant...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research

Treating simple benign esophageal strictures with savary-gilliard dilators: is the rule of three still necessary?
CONCLUSION: The rule of three in patients with simple benign esophageal strictures secondary to esophageal webs, Schatzki rings and peptic strictures treated with Savary-Gilliard dilators is not necessary, showing good clinical results. Prospective studies with more patients are necessary.RESUMO CONTEXTO: A dilata ção por velas é considerada uma técnica eficaz para o tratamento de estenoses esofágicas benignas simples. A “ regra de tr ês ” tem sido defendida para prevenir eventos adversos relatados, como sangramento e perfura ção. No entanto, a adesã...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research

ASSOCIATION OF TNF- α-308G>A POLYMORPHISM WITH SUSCEPTIBILITY TO CELIAC DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS
CONCLUSION: Our meta-analysis suggests that the TNF- α -308G>A polymorphism plays an important role in celiac disease susceptibility. However, our results are still needed to strengthen by further studies in different ethnicities and larger sample sizes.RESUMO CONTEXTO: H á evidências crescentes para mostrar que o TNF- α -308G>A polimorfismo pode ser um fator de risco para a doen ça celíaca, mas os resultados são inconsistentes. OBJETIVO: Por isto objetivou-se realizar uma meta-análise envolvendo estudos publicados até janeiro de 2019 para elucidar esta asso...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research

Ultrasonography in determining the rectal diameter and rectal wall thickness in children with and without constipation: a case-control study
CONCLUSION: Transabdominal rectal diameter measurement may be useful in the diagnosis of constipation.RESUMO CONTEXTO: A ultrassonografia tem sido demonstrada como útil no diagnóstico de constipação. OBJETIVO: O objetivo deste estudo foi comparar o diâmetro retal e a espessura da parede retal em crianças com e sem constipação. MÉTODOS: Foram incluídas no estudo crianças com diagnóstico de constipação de acordo com os critérios de Roma III. A s crianças foram submetidas à ultrassonografia abdominal com bexig...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research

Is the physician expertise in digital rectal examination of value in detecting anal tone in comparison to anorectal manometry?
CONCLUSION: More experienced colorectal surgeons used to DRE had a more significant agreement with the ARM, thereafter would have more appropriate therapeutic management to patients with sphincter functional problems. ARM, therefore, persists as an important exam to objectively evaluate the sphincter complex, justifying its utility in the clinical practice.RESUMO CONTEXTO: Exame anorretal digital (EAD) faz parte do exame f ísico, também é essencial para a avaliação do cirurgião colorretal. Um bom EAD oferece informações preciosas relacionadas às queixas do paci...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research

Multivariate analysis of biliary flow-related factors and post-kasai survival in biliary atresia patients
ABSTRACT BACKGROUND: Biliary atresia represents the most common surgically treatable cause of cholestasis in newborns. If not corrected, secondary biliary cirrhosis invariably results. OBJECTIVE: To evaluate, through multivariate analysis, the prognostic factors associated with the presence of biliary flow and survival with the native liver following Kasai portoenterostomy. METHODS: The study analyzed data from 117 biliary atresia patients who underwent portoenterostomy and had suitable histological material for evaluation. A logistic regression model was used to assess the presence of biliary flow. Survival was investigat...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research

[article partial retraction] prevalence of helicobacter pylori infection in dyspeptic patients and its association with clinical risk factors for developing gastric adenocarcinoma
ABSTRACT BACKGROUND: In Brazil, particularly in the underdeveloped localities, the prevalence of Helicobacter pylori (H. pylori) infections can range up to 90%. These rates are higher in older individuals and vary by country region. H. pylori infections are linked to the development of gastric pathologies, namely mild to moderate gastritis, gastroenteritis, peptic ulcer, intestinal metaplasia, and gastric cancer. In 1994, this organism was classified by the International Agency for Research on Cancer (IARC) as pertaining to the Group 1 carcinogen for gastric adenocarcinoma etiology. Gastric cancer represents a significant ...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research

Predictors of unsuccessful of treatment for fecal incontinence biofeedback for fecal incontinence in female
ABSTRACT BACKGROUND: Biofeedback is an effective method of treatment for fecal incontinence but there is controversy regarding factors that may be correlated with its effectiveness. OBJECTIVE: To evaluate the efficacy of biofeedback in the treatment of fecal incontinence, identifying the predictive factors for unsuccessful treatment. METHODS: Consecutive female patients who had fecal incontinence and were treated with a full course of biofeedback were screened. The symptoms were evaluated using Cleveland Clinic incontinence (CCF) score before and six months after the completion of therapy. Patients had a satisfactory clini...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research

Bariatric surgery and binge eating disorder: should surgeons care about it? a literature review of prevalence and assessment tools
CONCLUSION: Study heterogeneity accounted for the variability of the results from different centers and methodological flaws such as insufficient sample size and selection bias impaired the evidence on the magnitude of BED in surgical settings. For the sake of comparability and generalizability of the findings in future studies, researchers must recruit representative samples of treatment-seeking candidates for bariatric surgery and systematically apply standard instruments for the assessment of BED.RESUMO CONTEXTO: Os transtornos alimentares entre os candidatos à cirurgia bariátrica são comuns e est&a...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research