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Delivery of Hypoxia-Inducible Heme Oxygenase-1 Gene for Site-Specific Gene Therapy in the Ischemic Stroke Animal Model
Conclusions pEpo-SV-HO-1 induced HO-1 gene expression and therapeutic effect in the ischemic brain. Therefore, pEpo-SV-HO-1 may be useful for site-specific gene therapy of ischemic stroke.
Source: Pharmaceutical Research - July 30, 2016 Category: Drugs & Pharmacology Source Type: research

From Leptin, DEXA, and Beyond
Kahn and Bullard “recommend that waist circumference be added to BMI [body mass index] as a primary tool for assessing adiposity.”1 Suggesting “a need for alternative approaches to anthropometry”1 is necessary because BMI incorrectly classifies obesity by 39%.2 Many adults are obese by American Society of Ba riatric Physicians criteria of body fat: ≥25% for men and ≥30% for women.3 Normal-weight obese adults have increased mortality risk from diabetes, hypertension, heart disease, stroke, cancer, dyslipidemia, liver and gallbladder disease, sleep apnea and respiratory problems, and osteoarthritis.
Source: The American Journal of Medicine - July 28, 2016 Category: Journals (General) Authors: Eric R. Braverman Tags: AJM online Source Type: research

Hyperglycemia Is Associated with Impaired Muscle Quality in Older Men with Diabetes: The Korean Longitudinal Study on Health and Aging.
CONCLUSION: Poor glycemic control in these older patients with diabetes was associated with significant risk of decreased muscle quality and performance status. Glycemic control with an HbA1c of <8.5% might be needed to reduce the risk of adverse skeletal and functional outcomes in this population. PMID: 27126884 [PubMed]
Source: Diabetes and Metabolism Journal - April 30, 2016 Category: Endocrinology Tags: Diabetes Metab J Source Type: research

Association of dynamics in lean and fat mass measures with mortality in frail older women
Conclusion Low body fat or a pronounced decline in adiposity is associated with increased risks of mortality in frail older women. These results indicate a need to re-evaluate healthy weight in persons with frailty.
Source: The Journal of Nutrition, Health and Aging - April 21, 2016 Category: Nutrition Source Type: research

The relationship between bone mineral density and cerebral pulsatility index in patients with acute ischemic stroke (P6.025)
Conclusions: Our findings indicate that decreased BMD may be associated with atherosclerosis in the cerebral circulation.Disclosure: Dr. Park has nothing to disclose. Dr. Park has nothing to disclose. Dr. Suk has nothing to disclose. Dr. Koh has nothing to disclose. Dr. Hwang has nothing to disclose. Dr. Song has nothing to disclose. Dr. Lee has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Park, J. H., Park, J. H., Suk, S.-H., Koh, I.-S., Hwang, S.-H., Song, H.-K., Lee, J. H. Tags: Ischemic Stroke Diagnosis Source Type: research

Correlation between tibial measurements using peripheral quantitative computed tomography and hip areal bone density measurements in ambulatory chronic stroke patients.
CONCLUSIONS: Based on the good correlations between tibial pQCT variables and hip aBMD, the clinical use of pQCT in assessing bone health in this population should be further pursued. PMID: 26647174 [PubMed - as supplied by publisher]
Source: Brain Injury - February 14, 2016 Category: Neurology Tags: Brain Inj Source Type: research

The effect of swimming and type of stroke on bone metabolism in competitive adolescent swimmers: a pilot study.
CONCLUSION: This was the first study to evaluate the effect of swimming stroke on BMD. Although no effect was statistically shown, further studies with a larger series may determine this effect. PMID: 26422853 [PubMed - indexed for MEDLINE]
Source: Turkish Journal of Medical Sciences - December 2, 2015 Category: Journals (General) Tags: Turk J Med Sci Source Type: research

10 Must-Do Health Checks For Women Over 50
This article first appeared on the Golden Girls Network blog. Earlier on Huff/Post50: -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website.
Source: Healthy Living - The Huffington Post - October 31, 2015 Category: Consumer Health News Source Type: news

Chronic effects of stroke on hip bone density and tibial morphology: a longitudinal study
Conclusions There is evidence of continuous trabecular bone loss in the paretic tibial distal epiphysis among chronic stroke patients, but it tends to plateau after 2 years of stroke onset. The steady state may have been reached earlier in the hip and tibial diaphysis.
Source: Osteoporosis International - September 2, 2015 Category: Orthopaedics Source Type: research

Dynamic changes in left ventricular mass and in fat-free mass in top-level athletes during the competitive season
Conclusions Changes in LVM occur in close association with changes in FFM, suggesting that the left ventricle adapts concurrently with the increase of the metabolically active tissue induced by training, i.e. the FFM. Therefore, the dynamic changes in FFM and LVM may reflect a physiological adaptation induced by intensive training.
Source: European Journal of Preventive Cardiology - December 15, 2014 Category: Cardiology Authors: D'Ascenzi, F., Pelliccia, A., Cameli, M., Lisi, M., Natali, B. M., Focardi, M., Giorgi, A., D'Urbano, G., Causarano, A., Bonifazi, M., Mondillo, S. Tags: Original scientific paper Source Type: research

Predictors of low bone mineral density of the stroke-affected hip among ambulatory individuals with chronic stroke
Conclusion Low BMD of the stroke-affected side hip is prevalent in over a third of individuals with lower limb motor impairments. These individuals may be at particular risk of accelerated loss of BMD at the hip from asymmetrical gait pattern and poor affected-side ankle dorsiflexor strength. These impairments are intervention targets that may be addressed during rehabilitation which includes resistance training and addresses gait impairments.
Source: Osteoporosis International - October 22, 2014 Category: Orthopaedics Source Type: research

Is the negative relationship between obesity and bone mineral content greater for older women?
In conclusion, this study shows that the negative relationship between waist circumference and BMC in the femoral neck and total hip is greater for older women.
Source: Journal of Bone and Mineral Metabolism - September 1, 2014 Category: Orthopaedics Source Type: research

Multi-frequency bioelectrical impedance analysis for assessing fat mass and fat-free mass in stroke or transient ischaemic attack patients
K Myint
Source: European Journal of Clinical Nutrition - January 8, 2014 Category: Nutrition Authors: M W KafriJ F PotterP K Myint Tags: multi-frequency bioelectrical impedance analysis (MF-BIA) dual energy X-ray absorptiometry (DEXA) fat-free mass fat mass validity Source Type: research

Associations of Serum C-Peptide Level with Body Fat Distribution and Ever Stroke in Nondiabetic Subjects
Conclusion: The serum C-peptide level is strongly associated with the ever stroke in nondiabetic subjects and significantly associated with total and regional body fat distribution.
Source: Journal of Stroke and Cerebrovascular Diseases - October 17, 2013 Category: Neurology Authors: Ying Li, Lu Meng, Yue Li, Yasuto Sato Tags: Original Articles Source Type: research

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