Filtered By:
Therapy: Radiation Therapy
This page shows you your search results in order of relevance. This is page number 9.
Order by Relevance | Date
Total 256 results found since Jan 2013.
In Regard to Sanford et al
To the Editor: We read with interest Sanford et al's report (1) on their prospective study examining fractionated radiation therapy (RT) for residual/recurrent benign meningioma after resection; we applaud the authors for being the first to conduct such a study and for demonstrating the integrity and courage to present their complications whole heartedly. Although the 98% 10-year and 90% 15-year local control rates are impressive, we were particularly alarmed at the more than 20% stroke rate at the authors' median 17-year follow up (along with the near 60% rate of grade 2+ toxicity).
Source: International Journal of Radiation Oncology * Biology * Physics - January 31, 2018 Category: Radiology Authors: Shearwood McClelland, Timur Mitin, Jeremy N. Ciporen Tags: Comment Source Type: research
Radiotherapy in acromegaly: long-term brain parenchymal and vascular magnetic resonance changes
Conclusions RT seems to have created a cohort of patients with brain parenchymal changes whose clinical and cognitive impact is still unknown. These patients might require a prolonged MRI and MRA follow-up to promptly detect delayed RT-related complications and minimize their clinical consequences.
Source: Journal of Neuroradiology - March 2, 2018 Category: Radiology Source Type: research
A Reanalysis of Predictors for the Risk of Hemorrhage in Brain Arteriovenous Malformation
Brain arteriovenous malformation (BAVM) is a congenital cerebral vascular disease that characterized with intracranial hemorrhage and epilepsy. It has some risk in current treatments including microsurgery, endovascular, and radiation therapy. Some patients with bAVMs may keep unruptured in their whole life. Whether it should be treated depends on the evaluation of the hemorrhage risk of bAVM. Although previous studies gave many significant predictors, we tried to find some new and more significant predictors in 173 patients with bAVMS by retrospective analysis.
Source: Journal of Stroke and Cerebrovascular Diseases - April 2, 2018 Category: Neurology Authors: Zheng Huang, Kang Peng, Changqing Chen, Feiyue Zeng, Junyu Wang, Fenghua Chen Source Type: research
Surgical management of giant sphenoid wing meningiomas encasing major cerebral arteries.
CONCLUSIONS Although these giant lesions encasing major cerebral arteries are particularly treacherous for surgery, this series demonstrates that it is possible to safely achieve radical removal and at times even gross-total resection. However, the risk of recurrence remains high and larger studies are needed to see if and how improvement can be achieved, whether in surgical technique or technological advances, and by determining the timing and modality of adjuvant radiation therapy.
PMID: 29606042 [PubMed - in process]
Source: Neurosurgical Focus - April 1, 2018 Category: Neurosurgery Authors: Champagne PO, Lemoine E, Bojanowski MW Tags: Neurosurg Focus Source Type: research
A Reanalysis of Predictors for the Risk of Hemorrhage in Brain Arteriovenous Malformation
Brain arteriovenous malformation (BAVM) is a congenital cerebral vascular disease that characterized with intracranial hemorrhage and epilepsy. It has some risk in current treatments including microsurgery, endovascular, and radiation therapy. Some patients with bAVMs may keep unruptured in their whole life. Whether it should be treated depends on the evaluation of the hemorrhage risk of bAVM. Although previous studies gave many significant predictors, we tried to find some new and more significant predictors in 173 patients with bAVMS by retrospective analysis.
Source: Journal of Stroke and Cerebrovascular Diseases - April 2, 2018 Category: Neurology Authors: Zheng Huang, Kang Peng, Changqing Chen, Feiyue Zeng, Junyu Wang, Fenghua Chen Source Type: research
A 15-Year-Old Girl With Sudden Onsent Reversible Neurologic Symptoms After Cranial Irradiation for Medulloblastoma
A 15-year-old girl with history of medulloblastoma was evaluated for headache and neurologic deficits 5 years after completion of initial radiation therapy and 3 years following completion of reirradiation. Neurologic examination was notable for new-onset left hemianopia, hemiparesis, and neglect. Magnetic resonance imaging showed extensive areas of cortical T2 prolongation and thickening involving the right parietal, occipital, and temporal lobes with associated extensive gyral enhancement. Upon spontaneous resolution of her weakness after 4 days, repeat magnetic resonance imaging showed resolution of the edema and gyral ...
Source: Seminars in Pediatric Neurology - April 1, 2017 Category: Neurology Authors: Elizabeth Duke, Nicole J. Ullrich Source Type: research
Seizures with Migraine-like Attacks after Radiation Therapy (SMART) A new meaning of an old acronym
Stroke-like migraine attacks after radiation therapy (SMART) is a late-onset complication of cranial irradiation, clinically characterized by headache, seizures and focal deficits, with suggestive MRI changes. Clinical and neuroimaging findings typically resolve after a few weeks [1]. Seizures or status epilepticus are reported in 69% of SMART patients [2,3].
Source: Seizure: European Journal of Epilepsy - June 15, 2018 Category: Neurology Authors: Edoardo Ferlazzo, Michele Ascoli, Sara Gasparini, Vittoria Cianci, Damiano Branca, Chiara Sueri, Umberto Aguglia Tags: Short communication Source Type: research
Seizures with Migraine-like Attacks after Radiation Therapy (SMART): A new meaning of an old acronym
We describe two patients with SMART presenting with focal status epilepticus and headache. We believe that SMART is a misnomer that misjudge seizures among clinical features and we suggest to rename this entity as " Seizure with Migraine-like Attacks after Radiation Therapy". The new acronym, modified in its meaning but not in its form (SMART), better reflects the main clinical features and may allow neurologists to recognize this condition more easily.
Source: Seizure: European Journal of Epilepsy - June 15, 2018 Category: Neurology Authors: Edoardo Ferlazzo, Michele Ascoli, Sara Gasparini, Vittoria Cianci, Damiano Branca, Chiara Sueri, Umberto Aguglia Tags: Short communication Source Type: research
CAR 2. Results of Carotid Artery Stenting in a Belgian “Real-World” Practice
Carotid artery stenting (CAS) is a valuable solution for the treatment of carotid artery stenosis in a population of patients at high risk for carotid endarterectomy (CEA). This high-risk population includes patients with recurrent stenosis after CEA, high/low lesion, contralateral laryngeal nerve palsy, previous radical neck surgery, cervical radiation therapy, and tracheostomy. In the European Society for Vascular Surgery guidelines, however, the authors were concerned about the death and stroke rates of CAS in “real-world” practice.
Source: Journal of Vascular Surgery - October 22, 2018 Category: Surgery Authors: Laura Kerselaers, Sarah Gallala, Dimitri Aerden, Karl Von Kemp, Erik Debing Source Type: research
Medical Conditions Among Survivors of Adolescent and Young Adult Non-Hodgkin Lymphoma (NHL), Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML)
Conclusion: This study found that sociodemographic factors were associated with the risk of developing medical conditions in AYA NHL, ALL and AML survivors. As expected, the risk of medical conditions varied by cancer type and treatment, with those undergoing SCT having a higher risk of medical conditions regardless of cancer type. NHL and ALL survivors who were uninsured or publicly insured were at a consistently higher risk of developing medical conditions, as were Hispanic ALL survivors and Black AML survivors. Our findings highlight the higher burden of medical conditions in subgroups of cancer survivors that may relat...
Source: Blood - November 21, 2018 Category: Hematology Authors: Keegan, T. H. M., Muffly, L. S., Li, Q., Alvarez, E., Brunson, A. M., Malogolowkin, M., Wun, T. Tags: 904. Outcomes Research-Malignant Conditions: Real World Outcomes Source Type: research
Study unveils a blueprint for treating a deadly brain tumor
(NIH/National Institute of Neurological Disorders and Stroke) In a study of mice and human brain tumors researchers at the University of the Michigan, Ann Arbor, searched for new treatments by exploring the reasons why some patients with gliomas live remarkably longer than others. The results suggested that certain patients' tumor cells are less aggressive and much better at repairing DNA than others but are difficult to kill with radiation. The researchers then showed that combining radiation therapy with cancer drugs designed to block DNA repair may be an effective treatment strategy.
Source: EurekAlert! - Cancer - February 19, 2019 Category: Cancer & Oncology Source Type: news
Surgical Management of Deep-Seated Metastatic Brain Tumors Using Minimally Invasive Approaches
Conclusion This minimally invasive approach can be used to achieve extensive resection with minimal morbidity for arguably the highest risk metastatic brain tumors. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents | Abstract | Full text
Source: Journal of Neurological Surgery Part A: Central European Neurosurgery - March 19, 2019 Category: Neurosurgery Authors: Gassie, Kelly Alvarado-Estrada, Keila Bechtle, Perry Chaichana, Kaisorn L. Tags: Original Article Source Type: research
Stroke-like migraine attacks after radiation therapy (SMART) syndrome
ABSTRACT The present article provides the historical background of the Sociedade Brasileira de Doen ças Cerebrovasculares (Brazilian Society for Cerebrovascular Diseases), including details on its function, structure, challenges and main achievements.RESUMO O presente texto apresenta um relato hist órico da Sociedade Brasileira de Doenças Cerebrovasculares, incluindo detalhes da sua fundação, estruturação, dificuldades e principais realizações.
Source: Arquivos de Neuro-Psiquiatria - April 4, 2019 Category: Neurology Source Type: research
Left Thalamus Arteriovenous Malformation Secondary to Radiation Therapy of Original Vermian Arteriovenous Malformation: Case Report
A 70-year-old gentleman with history of hypothyroidism, hyperlipidemia, hypertension, and right superior cerebellar aneurysm presented to the neurosurgery service in 2008 with vertigo. Diagnostic cerebral angiography performed that year demonstrated a vermian arteriovenous malformations (AVM). The patient underwent stereotactic proton beam radiosurgery, which resulted in a decrease in flow and size of the lesion, and the patient was lost to follow-up. Now at the age of 80, the patient presented with acute gait instability.
Source: Journal of Stroke and Cerebrovascular Diseases - April 7, 2019 Category: Neurology Authors: Carlos Torres-Quinones, Matthew J. Koch, Scott B. Raymond, Aman Patel Tags: Case Report Source Type: research
NAMPT as a Dedifferentiation-Inducer Gene: NAD+ as Core Axis for Glioma Cancer Stem-Like Cells Maintenance
Conclusion and Perspectives
Gliomas are the most prevalent primary brain cancer in adults and include a broad category of tumors including astrocytoma, oligodendroglioma, and GBM. Regardless of tumor aggressiveness, malignancy, and infiltration, these glia-derived tumors rarely exceed a median survival time of 12–14 months. Driven by the infiltrative nature of these tumors, the clinical approach is difficult and relapses often occur with fatal consequences. These unsuccessful attempts to control glioma's fate have fostered research looking for more effective therapies.
(GSCs) are a small subset of CD133&#...
Source: Frontiers in Oncology - May 2, 2019 Category: Cancer & Oncology Source Type: research
