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Nutrition: Sodium Chloride
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Total 383 results found since Jan 2013.
Mitochondrial Deacetylase Sirt3 Reduces Vascular Dysfunction and Hypertension While Sirt3 Depletion in Essential Hypertension Is Linked to Vascular Inflammation and Oxidative Stress.
Conclusions: We suggest that Sirt3 depletion in hypertension promotes endothelial dysfunction, vascular hypertrophy, vascular inflammation and end-organ damage. Our data support a therapeutic potential of targeting Sirt3 expression in vascular dysfunction and hypertension.
PMID: 31852393 [PubMed - as supplied by publisher]
Source: Circulation Research - December 18, 2019 Category: Cardiology Authors: Dikalova AE, Pandey AK, Xiao L, Arslanbaeva L, Sidorova T, Lopez MG, Billings Iv FT, Verdin E, Auwerx J, Harrison DG, Dikalov SI Tags: Circ Res Source Type: research
Is the reduction of salt in the bread consumed in Morocco could be a means of protection against cardiovascular diseases?
ConclusionThis study highlights the effectiveness of awareness campaigns through the KAP for reducing the use of salt in bread-making. Knowing that the daily consumption of bread in Morocco varied between 360 and 500 g, this reduction of 26.3% of the salt in the bread certainly has a very positive impact on the CVD protection.
Source: Archives of Cardiovascular Diseases Supplements - January 7, 2020 Category: Cardiology Source Type: research
Incidence, clinical characteristics, and risk factors of peripartum cardiomyopathy in Nigeria: results from the PEACE Registry
ConclusionsIn Nigeria, the burden of PPCM was greatest in the North –West zone, which has the highest known incidence. PPCM was predicted by sociodemographic factors and pre‐eclampsia, which should be considered in its control at population level. Postpartum customary birth practices and Hausa–Fulani ethnicity were not associated with PPCM in Nigeria.
Source: ESC Heart Failure - January 27, 2020 Category: Cardiology Authors: K.M. Karaye,
N.A. Ishaq,
H. Sa'idu,
S.A. Balarabe,
M.A. Talle,
M.S. Isa,
U.G. Adamu,
H. Umar,
H.I. Okolie,
M.N. Shehu,
I.Y. Mohammed,
B. Sanni,
O.S. Ogah,
I. Oboirien,
E.M. Umuerri,
A.C. Mankwe,
V.Y. Shidali,
P. Njoku,
S. Dodiyi ‐Manue Tags: Original Research Article Source Type: research
A novel dried blood spots analysis combined with on-spot reaction for determination of trimethylamine N-oxide and its related compounds.
Abstract
The application of dried blood spots in clinical research is becoming increasingly popular owing to its convenient collection, storage, and transportation compared to that of conventional biological samples. The potential of trimethylamine N-oxide and its related compounds as biomarkers for various cardiovascular diseases, such as atherosclerosis, stroke, thrombosis, and heart failure, was recently highlighted, which was the driving force behind the development of an analytical method to identify trimethylamine N-oxide and eight related compounds in dried blood spots. In the proposed method, a novel "on-s...
Source: Talanta - January 30, 2020 Category: Chemistry Authors: Cho HD, Kim J, Lee JY, Kim YY, Lee Y, Jo E, Suh JH, Lee J, Cha S, Han SB Tags: Talanta Source Type: research
Sodium reduction in Turkey breast meat by using sodium anion species
This study aims at reducing the overall sodium content in turkey meat application by using alternative sodium species. Initial experiments studied the sodium absorption across the temperature range of 4 to 90 °C which showed higher sodium content for thermally processed samples over a longer cooking time. Overall, the adsorption rate was found to be slower and was not affected by protein denaturation. Additional experiments studied the sodium diffusion by replacing sodium chloride with alternative sodium salts with comparatively larger anions, which resulted in, 20–46% reduction in overall sodium content of thermally ...
Source: LWT Food Science and Technology - February 4, 2020 Category: Food Science Source Type: research
The hypotensive effect of salt substitutes in stage 2 hypertension: a systematic review and meta-analysis
Hypertension (HTN) is a ubiquitous risk factor for numerous non-communicable diseases, including cardiovascular disease and stroke. There are currently no wholly effective pharmacological therapies for subject...
Source: BMC Cardiovascular Disorders - February 27, 2020 Category: Cardiology Authors: Sadegh Jafarnejad, Hamed Mirzaei, Cain C. T. Clark, Mohsen Taghizadeh and Armin Ebrahimzadeh Tags: Research article Source Type: research
Sodium Handling and Interaction in Numerous Organs.
Abstract
Salt (NaCl) is a prerequisite for life. Excessive intake of salt, however, is said to increase disease risk including hypertension, arteriosclerosis, heart failure, renal disease, stroke, and cancer. Therefore, considerable research has been expended on the mechanism of sodium handling based on the current concepts of sodium balance. The studies have necessarily relied on relatively short-term experiments and focused on extremes of salt intake in humans. Ultra-long-term salt balance has received far less attention. We performed long-term salt balance studies at intakes of 6, 9, and 12 g/day and found that...
Source: American Journal of Hypertension - March 20, 2020 Category: Cardiology Authors: Minegishi S, Luft FC, Titze J, Kitada K Tags: Am J Hypertens Source Type: research
Correlation among high salt intake, blood pressure variability, and target organ damage in patients with essential hypertension: Study protocol clinical trial (SPIRIT compliant)
This study is a cross-sectional study. It will recruit 600 patients with essential hypertension in the outpatient and inpatient department of cardiovascular medicine of Chengdu Fifth People's Hospital. Researchers will obtain blood and urine samples with the patient's informed consent. In addition, we will measure patient's blood pressure and target organ-related information.
Trial registry:
The study protocol was approved by the Chengdu Fifth People's Hospital. Written informed consent will be obtained from all the participants. The trial was registered in the Chinese Clinical trial registry, ChiCTR2000029243. This tri...
Source: Medicine - April 1, 2020 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research
Our Diets Are Changing Because of the Coronavirus Pandemic. Is It for the Better?
The coronavirus pandemic has changed a lot about modern American life: how we work, socialize, and even how we eat. Dining out is a distant memory.
But nutritionally, people weren’t exactly thriving in pre-pandemic America. “Before COVID-19 came along, it was increasingly clear that the diet quality and nutritional status of Americans was terrible,” says Dr. Walter Willett, professor of epidemiology and nutrition at Harvard T.H. Chan School of Public Health. More than 40% of U.S. adults are obese. After years of declines, heart disease death rates are on the rise again. So are rates of obesity-linked canc...
Source: TIME: Health - April 28, 2020 Category: Consumer Health News Authors: Mandy Oaklander Tags: Uncategorized COVID-19 Source Type: news
Screening strategies for hypertension.
CONCLUSIONS: There is an implicit assumption that early detection of hypertension through screening can reduce the burden of morbidity and mortality, but this assumption has not been tested in rigorous research studies. High-quality evidence from RCTs or programmatic evidence from NRCTs on the effectiveness and costs or harms of different screening strategies for hypertension (mass, targeted, or opportunistic) to reduce hypertension-related morbidity and mortality is lacking.
PMID: 32378196 [PubMed - in process]
Source: Cochrane Database of Systematic Reviews - May 6, 2020 Category: General Medicine Authors: Schmidt BM, Durao S, Toews I, Bavuma CM, Hohlfeld A, Nury E, Meerpohl JJ, Kredo T Tags: Cochrane Database Syst Rev Source Type: research
AHA News: ' Angry and Depressed, ' Stroke Survivor Found Solace in Helping Others
FRIDAY, May 8, 2020 (American Heart Association News) -- Retired happily and resettled in a peaceful community near Salt Lake City, 70-year-old Doug Tapking is enjoying the good life– golfing and woodworking, singing in choirs with his wife,...
Source: Drugs.com - Daily MedNews - May 8, 2020 Category: General Medicine Source Type: news
Phosphodiesterase 3A and Arterial Hypertension.
Conclusions: The mutated PDE3A gene drives mechanisms that increase peripheral vascular resistance causing hypertension. We present two new animal models that will serve to elucidate the underlying mechanisms further. Our findings could facilitate the search for new antihypertensive treatments.
PMID: 32524868 [PubMed - as supplied by publisher]
Source: Circulation - June 10, 2020 Category: Cardiology Authors: Ercu M, Markó L, Schächterle C, Tsvetkov D, Cui Y, Maghsodi S, Bartolomaeus TUP, Maass PG, Zühlke K, Gregersen N, Hübner N, Hodge R, Mühl A, Pohl B, Molé-Illas R, Geelhaar A, Walter S, Napieczynska H, Schelenz S, Taube M, Heuser A, Anistan YM, Qadri Tags: Circulation Source Type: research
The incidence of recurrent cardiovascular events among acute coronary syndrome patients treated with generic or original clopidogrel in relation to their sociodemographic and clinical characteristics. The Aegean study.
Conclusions: The use of a generic clopidogrel besylate formulation was quite high in both urban and insular areas of Greece and had similar efficacy and safety profile with the original clopidogrel salt, supporting the routine use of this low-cost generic clopidogrel in the management of cardiovascular disease patients.
PMID: 32863989 [PubMed]
Source: Archives of Medical Science - August 31, 2020 Category: Biomedical Science Tags: Arch Med Sci Source Type: research
A high salt meal does not impair cerebrovascular reactivity in healthy young adults
A single high sodium meal compared to a low sodium meal does not impair cerebrovascular reactivity to hypercapnia or hypocapnia in healthy adults. MCA, Middle Cerebral Artery. AbstractA high sodium (Na+) meal impairs peripheral vascular function. In rodents, chronic high dietary Na+ impairs cerebral vascular function, and in humans, habitual high dietary Na+ is associated with increased stroke risk. However, the effects of acute high dietary Na+ on the cerebral vasculature in humans are unknown. The purpose of this study was to determine if acute high dietary Na+ impairs cerebrovascular reactivity in healthy adults. Thirty...
Source: Physiological Reports - October 10, 2020 Category: Physiology Authors: Kamila U. Migdal,
Austin T. Robinson,
Joseph C. Watso,
Matthew C. Babcock,
Shannon L. Lennon,
Christopher R. Martens,
Jorge M. Serrador,
William B. Farquhar Tags: ORIGINAL RESEARCH Source Type: research
