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Specialty: Neurology
Nutrition: Diets

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Total 302 results found since Jan 2013.

High-fructose diet during adolescent development increases neuroinflammation and depressive-like behavior without exacerbating outcomes after stroke
This study assesses the neuroinflammatory consequences of a peri-adolescent high-fructose diet model and assesses the impact of diet-induced metabolic dysfunction on behavioral and neuropathological outcomes after middle cerebral artery occlusion. We demonstrate that consumption of a high-fructose diet initiated during adolescent development increases brain complement expression, elevates plasma TNFα and serum corticosterone, and promotes depressive-like behavior. Despite these adverse effects of diet exposure, peri-adolescent fructose consumption did not exacerbate neurological behaviors or lesion volume after middle cer...
Source: Brain, Behavior, and Immunity - July 5, 2018 Category: Neurology Source Type: research

High-salt diet downregulates TREM2 expression and blunts efferocytosis of macrophages after acute ischemic stroke
In this study, whe...
Source: Journal of Neuroinflammation - April 12, 2021 Category: Neurology Authors: Mengyan Hu, Yinyao Lin, Xuejiao Men, Shisi Wang, Xiaobo Sun, Qiang Zhu, Danli Lu, Sanxin Liu, Bingjun Zhang, Wei Cai and Zhengqi Lu Tags: Research Source Type: research

Machine learning algorithms identify demographics, dietary features, and blood biomarkers associated with stroke records
We conducted a comprehensive evaluation of features associated with stroke records.
Source: Journal of the Neurological Sciences - July 8, 2022 Category: Neurology Authors: Jundong Liu, Elizabeth L. Chou, Kui Kai Lau, Peter Y.M. Woo, Jun Li, Kei Hang Katie Chan Source Type: research

Ischaemic stroke with multi-focal venous and arterial thrombosis due to hyperhomocysteinemia: anabolic androgenic steroid use and MTHFR c.667 C   >  T variant – a case report
Severely elevated serum homocysteine is a rare cause of ischaemic stroke and extra-cranial arterial and venous thrombosis. Several factors can lead to mild elevation of homocysteine including dietary folate an...
Source: BMC Neurology - April 26, 2023 Category: Neurology Authors: JPK Chen, A Rees, CH Coughlan, W Goodison, E Murphy and A Chandratheva Tags: Case Report Source Type: research

Stenosis Length and Degree Interact With the Risk of Cerebrovascular Events Related to Internal Carotid Artery Stenosis
Conclusion: We found a statistically insignificant tendency for the ultrasound-measured length of sICAS<70% to be longer than that of sICAS≥70%. Moreover, the ultrasound-measured length of sICAS<90% was significantly longer than that of sICAS 90%. Among patients with sICAS≥70%, the degree and length of stenosis were inversely correlated. Larger studies are needed before a clinical implication can be drawn from these results. Introduction Internal carotid artery stenosis (ICAS) causes around one-fifth of ischemic cerebrovascular stroke and has the highest risk of early stroke recurrence...
Source: Frontiers in Neurology - April 8, 2019 Category: Neurology Source Type: research

Potential Applications of Remote Limb Ischemic Conditioning for Chronic Cerebral Circulation Insufficiency
Conclusion Due to its long-term and often invisible course, CCCI has received less attention than acute cerebral ischemic stroke. However, without appropriate intervention, CCCI may lead to a variety of adverse events. Because the pathophysiological changes associated with CCCI are complex, pharmacological research in this area has been disappointing. Recent research suggests that RLIC, which is less invasive and more well-tolerated than drug treatment, can activate endogenous protective mechanisms during CCCI. In the present report, we reviewed studies related to CCCI (Table 1), as well as those related to stroke and sta...
Source: Frontiers in Neurology - May 2, 2019 Category: Neurology Source Type: research

Post-ischemic protein restriction induces sustained neuroprotection, neurological recovery, brain remodeling, and gut microbiota rebalancing
CONCLUSION: Moderate dietary protein restriction initiated post-ischemic stroke induces neurological recovery, brain remodeling, and neuroplasticity in mice by mechanisms involving antiinflammation and, in the post-acute phase, commensal gut microbiota rebalancing.PMID:34848338 | DOI:10.1016/j.bbi.2021.11.016
Source: Brain, Behavior, and Immunity - December 1, 2021 Category: Neurology Authors: Tayana Silva de Carvalho Vikramjeet Singh Ayan Mohamud Yusuf Jing Wang Adriana R Schultz Moreira Eduardo H Sanchez-Mendoza Maryam Sardari Luiza M Nascentes Melo Thorsten R Doeppner Jan Kehrmann Rene Scholtysik Ludger Hitpass Matthias Gunzer Dirk M Hermann Source Type: research

Cholestyramine resin administration alleviated cerebral ischemic injury in obese mice by improving gut dysbiosis and modulating the bile acid profile
In conclusion, Obesity induces gut dysbiosis, worsens stroke outcomes, and perturbs the BA profile. The dysbiotic microbiome is an important linkage between obesity and stroke. CR confers metabolic benefits and neuroprotective effects in obesity, perhaps by modulating gut microbial composition and BA metabolism.PMID:36179877 | DOI:10.1016/j.expneurol.2022.114234
Source: Experimental Neurology - September 30, 2022 Category: Neurology Authors: Jianhai Liang Mingsi Zhang Huidi Wang Yueran Ren Qiheng Wu Ranshi Huang Jiahui Xie Jia Yin Jiajia Zhu Source Type: research

High Dietary Glycemic Load is Associated with Poor Functional Outcome in Patients with Acute Cerebral Infarction.
CONCLUSIONS: Increased dietary GL and carbohydrate intake were associated with a poor short-term functional outcome after an acute ischemic stroke. PMID: 29629525 [PubMed]
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Modifiable Lifestyle Factors and Cognitive Function in Older People: A Cross-Sectional Observational Study
Conclusions: Lifestyle factors, such as physical activity, sleep, and social activity appear to be associated with cognitive function among older people. Physical activity and appropriate durations of sleep and conversation are important for cognitive function. Introduction Dementia is a major public health issue worldwide, with a serious burden for patients, caregivers, and society, as well as substantial economic impacts (1). Although the prevalence of late-life cognitive impairment and dementia are expected to increase in future, effective disease-modifying treatments are currently unavailable. Therefore, unders...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research