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Specialty: Neurology
Nutrition: Diets

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Total 302 results found since Jan 2013.

Monitoring risk and preventing ischemic stroke in the very old
This article examines current guidelines and evidence regarding medical management, lifestyle changes, and psychosocial interactions that can contribute to the primary and secondary prevention of ischemic stroke in the very old.AREAS COVERED: The authors conducted a literature search for ischemic stroke prevention and risk assessment in the elderly via PubMed. Furthermore, they describe current strategies for monitoring risk and preventing ischemic stroke in the elderly population.EXPERT OPINION: Ischemic stroke poses a significant health risk to the elderly, with prevention relying on managing modifiable risk factors such...
Source: Expert Review of Neurotherapeutics - August 4, 2023 Category: Neurology Authors: Mychael Delgardo Grant Rabin Thilan Tudor Anthony J Tang Geoffrey Reeves E Sander Connolly Source Type: research

Diabetic Stroke Promotes a Sexually Dimorphic Expansion of T Cells
AbstractWe recently reported that diabetes negates the cerebrovascular protection typically seen in adult female rats resulting in cognitive impairment, which is worsened by increased parenchymal bleeding and edema after ischemic stroke. Although women experience more severe diabetes and suffer from a higher rate of diabetic complications, including stroke and cognitive impairment, underlying mechanisms contributing to sex differences are limited. Emerging evidence suggests interleukin (IL)-17 contributes to cerebrovascular pathologies: (1) high salt diet-mediated expansion of IL-17-producing T cells (Th17) in the gut micr...
Source: NeuroMolecular Medicine - June 12, 2019 Category: Neurology Source Type: research

Mediterranean diet: The role of long-chain ω-3 fatty acids in fish; polyphenols in fruits, vegetables, cereals, coffee, tea, cacao and wine; probiotics and vitamins in prevention of stroke, age-related cognitive decline, and Alzheimer disease.
Authors: Román GC, Jackson RE, Gadhia R, Román AN, Reis J Abstract The mechanisms of action of the dietary components of the Mediterranean diet are reviewed in prevention of cardiovascular disease, stroke, age-associated cognitive decline and Alzheimer disease. A companion article provides a comprehensive review of extra-virgin olive oil. The benefits of consumption of long-chain ω-3 fatty acids are described. Fresh fish provides eicosapentaenoic acid while α-linolenic acid is found in canola and soybean oils, purslane and nuts. These ω-3 fatty acids interact metabolically with ω-6 fatty acids mainly linoleic...
Source: Revue Neurologique - September 16, 2019 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research

Effects of dietary 5-methoxyindole-2-carboxylic acid on brain functional recovery after ischemic stroke.
Abstract Stroke leads to devastating outcomes including impairments of sensorimotor and cognitive function that may be long lasting. New intervention strategies are needed to overcome the long-lasting effects of ischemic injury. Previous studies determined that treatment with 5-methoxyindole-2-carboxylic acid (MICA) conferred chemical preconditioning and neuroprotection against stroke. The purpose of the current study was to determine whether the preconditioning can lead to functional improvements after stroke (done by transient middle cerebral artery occlusion). After 4 weeks of MICA feeding, half the rats underw...
Source: Behavioural Brain Research - October 16, 2019 Category: Neurology Authors: Sumien N, Huang R, Chen Z, Vann PH, Wong JM, Li W, Yang S, Forster M, Yan LJ Tags: Behav Brain Res Source Type: research

Imbalance in the force: the dark side of the microbiota on stroke risk and progression.
Abstract The composition of the gut microbiota depends on many factors, including our lifestyle, diet, metabolism, antibiotic use and hygiene. The contribution of these factors in shaping the gut microbiota and the subsequent effects on the prevention and development of stroke has been under intense investigation. Furthermore, several reports have uncovered the impact of stroke on intestinal dysfunction and gut dysbiosis, highlighting the delicate interplay between the brain, gut and microbiome following this acute brain injury. Despite our growing appreciation of the gut microbiota in shaping brain health, the im...
Source: Current Opinion in Neurobiology - December 2, 2019 Category: Neurology Authors: Prame Kumar K, Wong CH Tags: Curr Opin Neurobiol Source Type: research

Secondary Prevention of Stroke: Study Protocol for a Telehealth-Delivered Physical Activity and Diet Pilot Randomized Trial (ENAbLE-Pilot)
Conclusion: This trial will produce evidence for the feasibility, safety, and potential effect of telehealth-delivered PA and DIET interventions for people with stroke. Results will inform development of an appropriately powered trial to test effectiveness to reduce major risk factors for recurrent stroke.Trial registration: ACTRN12620000189921.Cerebrovasc Dis
Source: Cerebrovascular Diseases - April 23, 2021 Category: Neurology Source Type: research

Stroke Prevention: Little-Known and Neglected Aspects
Combining available therapies has the potential to reduce the risk of stroke by 80% or more. A comprehensive review of all aspects of stroke prevention would be very lengthy; in this narrative review, we focus on some aspects of stroke prevention that are little-known and/or neglected. These include the following: (1) implementation of a Mediterranean diet; (2) B vitamins to lower homocysteine; (3) coordinated approaches to smoking cessation; (4) intensive lipid-lowering therapy; (5) lipid lowering in the elderly; (6) physiologically individualized therapy for hypertension based on renin/aldosterone phenotyping; (7) avoidi...
Source: Cerebrovascular Diseases - May 27, 2021 Category: Neurology Source Type: research

Nutrition in Stroke Prevention
Semin Neurol 2017; 37: 259-266 DOI: 10.1055/s-0037-1603470Nutrition is far more important to the prevention of stroke than most physicians realize. Key issues include a Mediterranean diet, the interaction of the intestinal microbiome, impaired renal function and diet, missed metabolic B12 deficiency, and the lowering of homocysteine with B vitamins to prevent stroke. The Cretan Mediterranean diet is high in olive oil, whole grains, fruits, vegetables, and legumes, and is close to a vegetarian diet. Compared with a low-fat diet, it reduced stroke by over 40%, and is clearly the best diet for diabetes. Metabolic B12 deficien...
Source: Seminars in Neurology - July 31, 2017 Category: Neurology Authors: Spence, J. David Tags: Review Article Source Type: research

N-Pep-12 supplementation after ischemic stroke positively impacts frequency domain QEEG
ConclusionA 90-day, 90 mg daily administration of N-Pep-12 had significant impact on some QEEG indicators in patients after supratentorial ischemic stroke, confirming possible enhancement of post-stroke neurorecovery. Further research is needed to consolidate our findings.
Source: Neurological Sciences - June 25, 2021 Category: Neurology Source Type: research

Effects of a Goal-Oriented Intervention on Self-Management Behaviors and Self-Perceived Burden After Acute Stroke: A Randomized Controlled Trial
Conclusion: The goal-oriented intervention based on Pender's health promotion model can effectively improve self-management behaviors and reduce physical and emotional SPB among stroke survivors.
Source: Frontiers in Neurology - July 20, 2021 Category: Neurology Source Type: research

Oropharyngeal dysphagia in stroke: diagnostic and therapeutic aspects.
CONCLUSION: The prevalence of oropharyngeal dysphagia is high after a stroke. Diagnosis should include a clinical evaluation and an instrumental examination, and thus objectively indicate the treatment, which will include compensatory and restorative measures with which to reduce the associated morbidity and mortality. PMID: 32500523 [PubMed - in process]
Source: Revista de Neurologia - June 6, 2020 Category: Neurology Authors: Terré R Tags: Rev Neurol Source Type: research

Identification of Risk Factors for Stroke in China: A Meta-Analysis of Prospective Cohort Studies
This study aimed to identify independent risk factors for first occurrence of stroke in Chinese individuals based on prospective cohort studies. Forty prospective cohort studies assessing 1,984,552 individuals were selected for the final meta-analysis. The identified risk factors for stroke in the Chinese population included old age (RR = 1.86, 95%CI: 1.47–2.36), hypertension (RR = 2.76, 95%CI: 2.26–3.37), cardiovascular disease history (RR = 1.98, 95%CI: 1.06–3.69), chronic kidney disease (RR = 1.65, 95%CI: 1.36–2.01), diabetes mellitus (RR = 1.71, 95%CI: 1.34–2.18), metabolic syndrome (RR = 1.59, 95%CI: 1.33–...
Source: Frontiers in Neurology - March 18, 2022 Category: Neurology Source Type: research

Health behavior of young patients with ischemic stroke in Estonia: A score of five factors
ConclusionsBefore stroke, young patients displayed significantly worse health behavior than the general population. The largest differences were found for smoking and obesity, and a cumulation of risk factors was observed via the HBSR score.
Source: Brain and Behavior - February 15, 2023 Category: Neurology Authors: Minni Saapar, Riina Vibo, Siim Schneider, Liisa K õrv, Sandra Mallene, Janika Kõrv Tags: ORIGINAL ARTICLE Source Type: research

Effects of N-Pep-12 dietary supplementation on neurorecovery after ischemic stroke
ConclusionThis exploratory clinical trial indicates a signal for the benefit of dietary supplementation with N-Pep-12 for the enhancement of neurorecovery after supratentorial ischemic stroke.
Source: Neurological Sciences - October 1, 2020 Category: Neurology Source Type: research

Benefits in quality of life following an obstructive sleep apnea screening and treatment program in patients with acute ischemic stroke
CONCLUSIONS: Although more evidence is needed, a significant improvement in QOL was suggested after our OSA intervention, particularly in patients with good CPAP adherence.PMID:36782347 | DOI:10.33588/rn.7604.2022359
Source: Revista de Neurologia - February 14, 2023 Category: Neurology Authors: A Dom ínguez-Mayoral C Guti érrez J S ánchez-Gómez S P érez-Sánchez N Fouz P Guerrero-Zamora M Ferrer M Aguilar V Galiani C Albal á J Moreno M A Gamero C Garc ía-Campos S Banda J Montaner Source Type: research