Filtered By:
Education: Study
Procedure: Gastroschisis Repair

This page shows you your search results in order of relevance. This is page number 19.

Order by Relevance | Date

Total 1790 results found since Jan 2013.

Incidence of Stroke Following Thoracic Endovascular Aortic Repair for Descending Aortic Aneurysm: A Systematic Review of the Literature with Meta-analysis
Stroke is an increasingly recognised complication following thoracic endovascular aortic repair (TEVAR). The aim of this study was to systematically synthesise the published data on perioperative stroke incidence during TEVAR for patients with descending thoracic aneurysmal disease and to assess the impact of left subclavian artery (LSA) coverage on stroke incidence.
Source: European Journal of Vascular and Endovascular Surgery - December 16, 2016 Category: Surgery Authors: R.S. von Allmen, B. Gahl, J.T. Powell Tags: Review Source Type: research

Editor's Choice – Incidence of Stroke Following Thoracic Endovascular Aortic Repair for Descending Aortic Aneurysm: A Systematic Review of the Literature with Meta-analysis
Stroke is an increasingly recognised complication following thoracic endovascular aortic repair (TEVAR). The aim of this study was to systematically synthesise the published data on perioperative stroke incidence during TEVAR for patients with descending thoracic aneurysmal disease and to assess the impact of left subclavian artery (LSA) coverage on stroke incidence.
Source: European Journal of Vascular and Endovascular Surgery - December 16, 2016 Category: Surgery Authors: R.S. von Allmen, B. Gahl, J.T. Powell Tags: Review Source Type: research

Incidence of Stroke Following Thoracic Endovascular Aortic Repair for Descending Aortic Aneurysm: A Systematic Review of the Literature with Meta-analysis
Stroke is an increasingly recognised complication following thoracic endovascular aortic repair (TEVAR). The aim of this study was to systematically synthesise the published data on perioperative stroke incidence during TEVAR for patients with descending thoracic aneurysmal disease and to assess the impact of left subclavian artery (LSA) coverage on stroke incidence.
Source: Journal of Vascular Surgery - February 22, 2017 Category: Surgery Authors: R.S. von Allmen, B. Gahl, J.T. Powell Tags: Selected Abstract from the February Issue of the European Journal of Vascular and Endovascular Surgery Source Type: research

Vascular Endothelial Growth Factor Isoform-B Stimulates Neurovascular Repair After Ischemic Stroke by Promoting the Function of Pericytes via Vascular Endothelial Growth Factor Receptor-1
In this study, we investigated the therapeutic potential of VEGF-B in ischemic stroke using different in vivo and in vitro approaches. We showed that the delayed intranasal administration of VEGF-B reduced neuronal damage and inflammation. Unexpectedly, VEGF-B stimulated the formation of stable brain microvasculature within the injured region by promoting the interaction between endothelial cells and pericytes. Our data indicate that the effects of VEGF-B were mediated via its specific receptor VEGF receptor-1 (VEGFR-1) that is predominately expressed in brain pericytes. Importantly, VEGF-B promoted the survival of pericyt...
Source: Molecular Neurobiology - March 13, 2017 Category: Neurology Source Type: research

Toll-Like Receptor 4 Signaling Pathway as a Potential Targets for Stroke-Induced Inflammation
Toll-like receptor 4 (TLR4) belongs to a large family of pattern recognition receptors that play a key role in innate immunity and inflammatory response. Increasing evidence has shown that TLR4 signaling pathway plays an essential role in mediating the immune response and central nervous system (CNS) repair and development. Brain inflammation and innate immunity has been implicated as a secondary injury mechanism following stroke, exacerbating neural damage to impede recovery. After stroke, a series of signaling pathways are triggered by dying cells or other factors in both the local innate immune cells in brain and other ...
Source: Current Signal Transduction Therapy - May 9, 2017 Category: Molecular Biology Source Type: research

Atheromatous disease of the aorta and perioperative stroke
Despite continued improvements in patient outcomes after cardiac surgery, stroke remains one of the most feared and devastating complications of cardiac surgery and is estimated to occur in 1.2% to 1.6% of patients undergoing coronary artery bypass grafting (CABG).1-3 The incidence of stroke increases for other common cardiac surgical procedures, and contemporary studies from the Society of Thoracic Surgeons database have reported perioperative stroke rates of 1.4% for mitral valve repair,4 1.5% for aortic valve replacement,5 2.1% for mitral valve replacement,4 and 6.6% for proximal aorta replacement.
Source: The Journal of Thoracic and Cardiovascular Surgery - September 13, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Nicholas D. Andersen, Stephen A. Hart, Ganesh P. Devendra, Esther S.H. Kim, Douglas R. Johnston, Jacob N. Schroder, Richard A. Krasuski Tags: Expert review Source Type: research

MicroRNA ‐365 modulates astrocyte conversion into neuron in adult rat brain after stroke by targeting Pax6
Abstract Reactive astrocytes induced by ischemia can transdifferentiate into mature neurons. This neurogenic potential of astrocytes may have therapeutic value for brain injury. Epigenetic modifications are widely known to involve in developmental and adult neurogenesis. PAX6, a neurogenic fate determinant, contributes to the astrocyte‐to‐neuron conversion. However, it is unclear whether microRNAs (miRs) modulate PAX6‐mediated astrocyte‐to‐neuron conversion. In the present study we used bioinformatic approaches to predict miRs potentially targeting Pax6, and transient middle cerebral artery occlusion (MCAO) to mo...
Source: Glia - February 16, 2018 Category: Neurology Authors: Jia ‐Lin Mo, Qi Liu, Zeng‐Wei Kou, Kun‐Wei Wu, Ping Yang, Xian‐Hua Chen, Feng‐Yan Sun Tags: RESEARCH ARTICLE Source Type: research

Initial cell maturity changes following transplantation in a hyaluronan-based hydrogel and impacts therapeutic success in the stroke-injured rodent brain.
Abstract Ischemic stroke results in a loss of neurons for which there are no available clinical strategies to stimulate regeneration. While preclinical studies have demonstrated that functional recovery can be obtained by transplanting an exogenous source of neural progenitors into the brain, it remains unknown at which stage of neuronal maturity cells will provide the most benefit. We investigated the role of neuronal maturity on cell survival, differentiation, and long-term sensorimotor recovery in stroke-injured rats using a population of human cortically-specified neuroepithelial progenitor cells (cNEPs) deliv...
Source: Biomaterials - November 15, 2018 Category: Materials Science Authors: Payne SL, Tuladhar A, Obermeyer JM, Varga BV, Teal CJ, Morshead CM, Nagy A, Shoichet MS Tags: Biomaterials Source Type: research

Inhibition of soluble epoxide hydrolase regulates monocyte/macrophage polarization and improves neurological outcome in a rat model of ischemic stroke
This study aimed to evaluate whether a selective sEH inhibitor, 12-(3-adamantan-1-yl-ureido)-dodecanoic acid (AUDA), can regulate monocyte/macrophage polarization and improve motor function in the rats with ischemic stroke induced by middle cerebral artery occlusion. We measured the infarct volume with 2,3,5-triphenyltetrazolium chloride staining and used the rotarod test to assess motor performance in rats. The monocyte/macrophage activation and mRNA expression of proinflammatory mediators were measured by flow cytometry and reverse-transcription quantitative PCR, respectively. Our results showed better neurological funct...
Source: NeuroReport - April 27, 2019 Category: Neurology Tags: DEGENERATION AND REPAIR Source Type: research

Understanding the therapeutic alliance in stroke rehabilitation.
Conclusions: Establishing and maintaining a therapeutic alliance appears to be an individualised and complex process. A clinician's ability to use their personal attributes therapeutically, and professional skills flexibly, appeared integral to relationship quality. IMPLICATIONS FOR REHABILITATION Developing therapeutic relationships requires a person-centred and sometimes family/whānau-centred approach. The judicious use of self-disclosure may achieve emotional proximity and yet maintain professional boundaries. Maintaining relationship health requires a proactive approach to detect and manage relationship disruptions. ...
Source: Disability and Rehabilitation - August 20, 2019 Category: Rehabilitation Authors: Bishop M, Kayes N, McPherson K Tags: Disabil Rehabil Source Type: research

Thyroid Hormones in the Brain and Their Impact in Recovery Mechanisms After Stroke
Thyroid hormones are of fundamental importance for brain development and essential factors to warrant brain functions throughout life. Their actions are mediated by binding to specific intracellular and membranous receptors regulating genomic and non-genomic mechanisms in neurons and populations of glial cells, respectively. Among others, mechanisms include the regulation of neuronal plasticity processes, stimulation of angiogenesis and neurogenesis as well modulating the dynamics of cytoskeletal elements and intracellular transport processes. These mechanisms overlap with those that have been identified to enhance recover...
Source: Frontiers in Neurology - October 17, 2019 Category: Neurology Source Type: research

Waggle needling wields preferable neuroprotective and anti-spastic effects on post-stroke spasticity rats by attenuating γ-aminobutyric acid transaminase and enhancing γ-aminobutyric acid.
This study was designed to compare the anti-spastic effect of waggle needling to the routine needling and to explore its underlying mechanism. We established post-stroke spasticity model based on ischemia stroke operation (middle cerebral artery occlusion). Rats were divided into six groups: normal control group, sham-operated control group, ischemia stroke model group, waggle needling group, routine needling group and baclofen group. Neurological function and muscle tone were assessed by the Zea Longa score and modified Ashworth scale, respectively. Indirect muscle tone was testified with electrophysiological recording. C...
Source: NeuroReport - June 9, 2020 Category: Neurology Tags: Degeneration and Repair Source Type: research

Demyelinating processes in aging and stroke in the central nervous system and the prospect of treatment strategy.
Abstract Demyelination occurs in response to brain injury and is observed in many neurodegenerative diseases. Myelin is synthesized from oligodendrocytes in the central nervous system, and oligodendrocyte death-induced demyelination is one of the mechanisms involved in white matter damage after stroke and neurodegeneration. Oligodendrocyte precursor cells (OPCs) exist in the brain of normal adults, and their differentiation into mature oligodendrocytes play a central role in remyelination. Although the differentiation and maturity of OPCs drive endogenous efforts for remyelination, the failure of axons to remyelin...
Source: CNS Neuroscience and Therapeutics - November 19, 2020 Category: Neuroscience Authors: Chen D, Huang Y, Shi Z, Li J, Zhang Y, Wang K, Smith AD, Gong Y, Gao Y Tags: CNS Neurosci Ther Source Type: research

Neurovascular Unit: A critical role in ischemic stroke.
Abstract Ischemic stroke (IS), a common cerebrovascular disease, results from a sudden blockage of a blood vessel in the brain, thereby restricting blood supply to the area in question, and making a significantly negative impact on human health. Unfortunately, current treatments, that are mainly based on a recanalization of occluded blood vessels, are insufficient or inaccessible to many stroke patients. Recently, the profound influence of the neurovascular unit (NVU) on recanalization and the prognosis of IS have become better understood; in-depth studies of the NVU have also provided novel approaches for IS trea...
Source: CNS Neuroscience and Therapeutics - January 2, 2021 Category: Neuroscience Authors: Wang L, Xiong X, Zhang L, Shen J Tags: CNS Neurosci Ther Source Type: research

Stem Cell Treatment for Ischemic Stroke Recovery
This report reviews the different biological repair approaches using cell implants, discusses clinical trial design and surgical methods, and the current state of research. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Seminars in Neurology - January 27, 2021 Category: Neurology Authors: Kondziolka, Douglas Tags: Review Article Source Type: research