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Meet the Co-Editor
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Source: Current Signal Transduction Therapy - December 23, 2021 Category: Molecular Biology Source Type: research

Meet Our Co-Editor
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Source: Current Signal Transduction Therapy - November 9, 2021 Category: Molecular Biology Source Type: research

Acknowledgements to Reviewers
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Source: Current Signal Transduction Therapy - November 3, 2021 Category: Molecular Biology Source Type: research

Development of ATP13A2-deficient In vitro Model for PARK9 Parkinson’s Disease
Conclusion: ATP13A2-deficient PD model was successfully developed. (Source: Current Signal Transduction Therapy)
Source: Current Signal Transduction Therapy - November 3, 2021 Category: Molecular Biology Source Type: research

Therapeutic Approaches for COVID-19 Based on the Interferon-Mediated Immune Responses
Conclusion: Altogether, administration of interferons or interferon-inducing agents in a prophylactic manner or at the early stages of the disease, could mimic the effective antiviral responses against SARS-CoV-2 and reduce the disease severity. At later stages of the disease, however, the balance of the immune reactions would be disrupted and the responses would shift toward immunopathogenic over-reactions, which could be exacerbated by the interferon usage. Moderating the activity of the immune system by anti-inflammatory agents, might be the optimum approach in such conditions. (Source: Current Signal Transduction Therapy)
Source: Current Signal Transduction Therapy - November 3, 2021 Category: Molecular Biology Source Type: research

Identification and Characterization of SNP Mutation in Genes Related to Non-small Cell Lung Cancer
Conclusion: The SNPs with the greater quality scores belonging to the above-said genes were identified, which gives us a baseline to understand the NSCLC at the Genomic level. Further fold change of these genes to the frequency of variants can be mapped to understand the NSCLC at a greater depth. (Source: Current Signal Transduction Therapy)
Source: Current Signal Transduction Therapy - November 3, 2021 Category: Molecular Biology Source Type: research

Sliding Mode Control of an Actuated Knee Joint Orthosis
Conclusion: In fact, position tracking and speed tracking errors are very small. The sliding mode controller effectively absorbs disturbance and parametric variations, hence the efficiency and robustness of our applied control. (Source: Current Signal Transduction Therapy)
Source: Current Signal Transduction Therapy - November 3, 2021 Category: Molecular Biology Source Type: research

Impact of Coronavirus Outbreak on Climate and Air Quality
All over the world, there is a new target of public health emergency looming the world along with an appearance and distribution of the novel coronavirus disease (2019-nCoV) also known as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). This Virus was initially generated in bats and then transferred to a human being over an unknown animal playing the role of a mediator in Wuhan, China, in December 2019. This virus is transmitted by breathing or coming in contact with an infected person’s droplets. The Incubation period is between 2 to 14 days for COVID-19, that is the time between exposure of the virus (pers...
Source: Current Signal Transduction Therapy - November 3, 2021 Category: Molecular Biology Source Type: research

IoT Solutions for Smart Management of Hospital Buildings: A General Review towards COVID-19, Future Pandemics, and Infectious Diseases
Conclusions: Some efforts have been made with purely signal strength-based positioning, but indoor environments have been shown to work inauspiciously for these kinds of methods. (Source: Current Signal Transduction Therapy)
Source: Current Signal Transduction Therapy - November 3, 2021 Category: Molecular Biology Source Type: research

Lessons Learned from the Covid-19 Outbreak and its Impact: A Generalized Study
An infectious disease emerged from Wuhan, China, in December 2019 and then spread to many countries worldwide. Initially, it was named Coronavirus disease 2019, and then it was called COVID-19. COVID-19 is an ongoing pandemic with 60.2 million confirmed cases and a leading health concern for the public worldwide. Mainly middle and old-aged people are being hospitalized and are dying across the affected countries. More than 1.42 million people have been deceased, and more than 41.5 million people have been recovered. Almost all the countries are fighting against the transmission of the virus by restricting travel and other ...
Source: Current Signal Transduction Therapy - November 3, 2021 Category: Molecular Biology Source Type: research

CircRNAs and Axes Involved in Thyroid Cancer based on PTC: A Biomarker for Prognosis, Diagnosis and Treatment
Conclusion: Briefly, this study provided an overview of the current understanding of the function of lncRNA and micro RNAs (miRNAs) along with their interactions in TC. (Source: Current Signal Transduction Therapy)
Source: Current Signal Transduction Therapy - November 3, 2021 Category: Molecular Biology Source Type: research

Trends and Applications of Brain Computer Interfaces
This article provides a comprehensive review of the recent trends and applications of BCIs. This review also provides future directions towards the acceleration and maturation of BCI technology. Based on a methodical search strategy, major technical databases were searched in quest of research papers of average and outstanding interest. A total of 188 research works were included within this review due to their suitability and state-of-the-art achievements. This review identifies various eminent applications of BCIs in medical and non-medical domains. The findings of this review reveal the need for further exploration of B...
Source: Current Signal Transduction Therapy - November 3, 2021 Category: Molecular Biology Source Type: research

Exploring the Abnormal Signal Transduction Mediated Internet Addiction and Gaming Disorders
The world is connected by the internet. It is very useful because we use Google to find out any new topic, to search for new places, to quest updated research, and to get knowledge for learning. People around the world can communicate with each other through the Google video conference talk. Internet is frequently used in smartphones, laptops, desktops, and tablets. Excessive affinity towards internet-based online data collection, downloading pictures, videos, cyber relationships, and social media may produce addiction disorders followed by different symptoms such as behavior change, mind disturbance, depression, anxiety, ...
Source: Current Signal Transduction Therapy - November 3, 2021 Category: Molecular Biology Source Type: research

Impact of Covid19 and its Treatment: A Report
Till now, across from a few basic data, nothing is well clear regarding its exact origin, incubation period, seriousness and what makes it transmissible is not recommended for COVID19 anywhere in the world. It was on 28 January, 2020 that the World Health Organisation released a paper relating to medical data and recommendations from the management of previous HCoV epidemics. The present paper outlines steps for the identification and assessment of patients with extreme acute respiratory disease; monitoring and infection prevention strategies; tracking and early intervention therapy; treatment of respiratory arrest and ARD...
Source: Current Signal Transduction Therapy - November 3, 2021 Category: Molecular Biology Source Type: research

How India Fights with COVID-19 Learning from Highly Affected Countries
It was 11 March 2020 when the World Health Organization (WHO) declared the name COVID-19 for coronavirus disease and also described it as a pandemic. Till that day 118,000 cases were confirmed of pneumonia with breathing problem throughout the world. At the start of New Year when COVID-19 came into knowledge a few days later, the gene sequencing of the virus was revealed. Today the number of confirmed cases is scary, i.e. 9,472,473 in the whole world and 484,236 deaths have been recorded by WHO till 26 June 2020. WHO's global risk assessment is very high [1]. The report is enlightening the lessons learned by India fro...
Source: Current Signal Transduction Therapy - November 3, 2021 Category: Molecular Biology Source Type: research