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Total 2334 results found since Jan 2013.

Does tumoral cavernous carotid stenosis predict an increased risk of future stroke in skull base meningiomas?
CONCLUSIONS: Acute stroke in patients with ICA encasement by SBMs is rare despite the propensity of these tumors to stenose the ICA. Patients with ICA stenosis secondary to their SBM did not have a higher incidence of stroke than those with ICA encasement without stenosis. The results of this study demonstrate that prophylactic intervention to prevent stroke is not necessary in ICA stenosis secondary to SBM.PMID:37178029 | DOI:10.3171/2023.4.JNS23378
Source: Journal of Neurosurgery - May 13, 2023 Category: Neurosurgery Authors: Joshua I Macarthur Frazer O'Brien Cathal John Hannan Charlotte Hammerbeck-Ward Omar N Pathmanaban Scott A Rutherford Rekha Siripurapu Andrew T King Wayne Ng Source Type: research

ASL MRI informs blood flow to chronic stroke lesions in patients with aphasia
In this study, we will determine if cerebral blood flow (CBF) mapped in patients with chronic strokes can be further used to understand stroke-related factors and behavior.Methods: We collected perfusion MRI data using pseudo-Continuous Arterial Spin Labeling (pCASL) using a single post-labeling delay of 2,200 ms in 14 chronic PWA, along with high-resolution structural MRI to compute maps of tissue damage using Tissue Integrity Gradation via T2w T1w Ratio (TIGR). To quantify the CBF in chronic stroke lesions, we tested at what point spatial smoothing should be applied in the ASL analysis pipeline. We then related CBF to t...
Source: Frontiers in Physiology - July 20, 2023 Category: Physiology Source Type: research

Predictive utility of stress tests in the detection of asymptomatic coronary artery disease in atherosclerotic stroke patients
CONCLUSION: Myocardial ischemia and CV events were infrequent and both strongly associated with ECG signs of necrosis, suggesting a low yield of stress tests and the potential for a more straightforward algorithm in the choice of patients eligible to coronary angiogram or other coronary imaging in post-stroke setting.PMID:37567133 | DOI:10.1016/j.jstrokecerebrovasdis.2023.107290
Source: Atherosclerosis - August 11, 2023 Category: Cardiology Authors: Jean-S ébastien Liegey Sami Fawaz Claire Ducos Yann Pucheu Romain Boulestreau Igor Sibon Thierry Couffinhal Source Type: research

Prediction of outcome in patients with suspected acute ischaemic stroke with CT perfusion and CT angiography: the Dutch acute stroke trial (DUST) study protocol
This study will provide insight in the added prognostic value of CTP and CTA parameters in outcome prediction of acute stroke patients. The prediction models that will be developed in this study may help guide future treatment decisions in the acute stage of ischaemic stroke.
Source: BMC Neurology - February 25, 2014 Category: Neurology Authors: Tom van SeetersGeert Jan BiesselsIrene van der SchaafJan Willem DankbaarAlexander HorschMerel LuitseJoris NiestenWillem MaliL KappelleYolanda van der GraafBirgitta Velthuis Source Type: research

Complexity analysis of beat‐to‐beat skin‐surface laser‐Doppler flowmetry signals in stroke patients
ConclusionLarger SampEn values of FRT can be partly attributed to the local regulatory activities that are present in the stroke subjects when facing the induced abnormal vascular conditions and blood flow perfusion resistance. The present findings could aid the development of a noninvasive monitoring technique that will enable discrimination of the different microcirculatory responses in stroke patients.This article is protected by copyright. All rights reserved.
Source: Microcirculation - April 22, 2015 Category: Research Authors: Chao‐Tsung Chen, Hsin Hsiu, Jin‐Shiang Fan, Fong‐Cheng Lin, Yen‐Ting Liu Tags: Original Research Source Type: research

Obstructive carotid and/or intracranial artery disease rarely affects the incidence of haemodynamic ischaemic stroke during cardiac surgery: a study on brain perfusion single-photon emission computed tomography with acetazolamide ADULT CARDIAC
CONCLUSIONS It is unusual for CIAD to affect the incidence of haemodynamic ischaemic stroke during cardiac surgery. Brain perfusion SPECT with acetazolamide is effective for narrowing down patients at high risk of ischaemic stroke during cardiac surgery. Meanwhile, the application of brain perfusion single-photon emission tomography should be confined only to patients with obstructive CIAD because it is an expensive examination tool.
Source: European Journal of Cardio-Thoracic Surgery - October 16, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Imasaka, K.-i., Yasaka, M., Tayama, E., Tomita, Y. Tags: Cardiac - other ADULT CARDIAC Source Type: research

Mechanical Thrombectomy Using the New ERIC Retrieval Device Is Feasible, Efficient, and Safe in Acute Ischemic Stroke: A Swiss Stroke Center Experience INTERVENTIONAL
CONCLUSIONS: In this observational study, the new ERIC retrieval device was technically feasible, safe, and effective in acute ischemic stroke with large-vessel occlusion.
Source: American Journal of Neuroradiology - January 13, 2016 Category: Radiology Authors: Kahles, T., Garcia-Esperon, C., Zeller, S., Hlavica, M., Anon, J., Diepers, M., Nedeltchev, K., Remonda, L. Tags: INTERVENTIONAL Source Type: research

External Counterpulsation Reduces Beat-to-Beat Blood Pressure Variability When Augmenting Blood Pressure and Cerebral Blood Flow in Ischemic Stroke.
CONCLUSIONS: ECP reduces the beat-to-beat BPV when increasing the blood pressure and cerebral blood flow velocity in ischemic stroke patients. ECP might be able to improve the clinical outcome by decreasing the beat-to-beat BPV in stroke patients, and this should be explored further in future studies. PMID: 27095525 [PubMed - as supplied by publisher]
Source: Journal of Clinical Neurology - April 22, 2016 Category: Neurology Tags: J Clin Neurol Source Type: research

Diagnostic and prognostic benefit of arterial spin labeling in subacute stroke
ConclusionsIn patients with subacute stroke, our study showed that adding perfusion imaging to structural imaging and clinical data significantly improved outcome prediction. This highlights the usefulness of ASL and noninvasive perfusion biomarkers in stroke diagnosis and management.
Source: Brain and Behavior - March 24, 2019 Category: Neurology Authors: Thoralf Thamm, Sarah Zweynert, Sophie K. Piper, Vince I. Madai, Michelle Livne, Steve Z. Martin, Cornelius X. Herzig, Matthias A. Mutke, Eberhard Siebert, Thomas Liebig, Jan Sobesky Tags: ORIGINAL RESEARCH Source Type: research

Early Ultrafast Ultrasound Imaging of Cerebral Perfusion correlates with Ischemic Stroke outcomes and responses to treatment in Mice
Conclusion: We thus provide the proof of concept that in a mouse model of thromboembolic stroke with an intact skull, early ultrafast ultrasound can be indicative of responses to treatment and cerebral tissue fates following stroke. It brings new tools to study ischemic stroke in preclinical models and is the first step prior translation to the clinical settings.
Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Vincent Hingot, Camille Brodin, Florent Lebrun, Baptiste Heiles, Audrey Chagnot, Merv é Yetim, Maxime Gauberti, Cyrille Orset, Mickael Tanter, Olivier Couture, Thomas Deffieux, Denis Vivien Tags: Research Paper Source Type: research

Human placenta mesenchymal stem cell protection in ischemic stroke is Angiotensin converting enzyme ‐2 (ACE‐2) and masR receptor dependent
In this study we demonstrated that hPMSC-derived ACE2 is required to protect against progressive loss of cerebral blood perfusion following ischemic stroke. This effect is also mediated through vascular endothelial Mas receptor but not AT2 receptor. Consequently, the results of our experimental stroke studies with human derived stem cells describes new paracrine function of hPMSC in which ACE2 and Mas receptor are critical, therefore, providing a novel therapeutic strategy for stroke in near future.
Source: Stem Cells - June 15, 2021 Category: Stem Cells Authors: Mansoureh Barzegar, Shantel Vital, Karen Y. Stokes, Yuping Wang, J. Winny Yun, Luke A. White, Oleg Chernyshev, Roger E. Kelley, Jonathan S. Alexander Tags: Regenerative Medicine Source Type: research

Update on Intensive Care Unit Management of Stroke
Anasthesiol Intensivmed Notfallmed Schmerzther. 2022 Mar;57(3):222-229. doi: 10.1055/a-1374-1932. Epub 2022 Mar 23.ABSTRACTIn this review, we provide an update on the intensive care unit (ICU) management of ischemic stroke. Over the last decade, new evidence has led to rapid changes in the early management of patients admitted with acute ischemic stroke. Nevertheless, stroke remains a leading cause of disability. Consequently, a significant number of patients with acute ischemic stroke require ICU level care. The most frequent reasons for ICU admissions are large infarction with potential swelling, reduced level of conscio...
Source: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS - March 23, 2022 Category: Intensive Care Authors: Farid Salih Alexandra Becker Nicolai Andrees Hannah Tempel Source Type: research