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Total 2082 results found since Jan 2013.

Prevalence of Patent Foramen Ovale in Ischaemic Stroke in Italy: Results of SISIFO Study
Conclusion: If any relationship exists between stroke and PFO, this is more likely in PACI and POCI at a younger age. Our results are consistent with recent findings that underline PFO alone must not be considered a significant independent predictor for stroke; so the presence of PFO alone doesn't permit rushed causal correlations or ‘therapeutic aggressiveness'.Cerebrovasc Dis 2015;39:162-169
Source: Cerebrovascular Diseases - February 26, 2015 Category: Neurology Source Type: research

Prehospital stroke diagnostics based on neurological examination and transcranial ultrasound
Conclusions The study demonstrates the feasibility and high diagnostic accuracy of emergency transcranial ultrasound assessment combined with neurological examinations for major ischemic stroke. Future combination with telemedical support, point-of-care analysis of blood serum markers, and probability algorithms of prehospital stroke diagnosis including ultrasound may help to speed up stroke treatment.
Source: Critical Ultrasound Journal - February 27, 2014 Category: Radiology Source Type: research

A pragmatic approach to sonothrombolysis in acute ischaemic stroke: the Norwegian randomised controlled sonothrombolysis in acute stroke study (NOR-SASS)
DiscussionNOR-SASS is the first randomised controlled trial designed to test the superiority of contrast enhanced ultrasound treatment given ≤4½ hours after stroke onset in an unselected acute ischaemic stroke population eligible or not eligible for intravenous thrombolysis, with or without a defined arterial occlusion on CTA. If a positive effect and safety can be proven, contrast enhanced ultrasound treatment will be an option for all acute ischaemic stroke patients. EudraCT No 201200032341; www.clinicaltrials.gov NCT01949961.
Source: BMC Neurology - July 11, 2015 Category: Neurology Authors: Aliona NacuChristopher KvistadNicola LogalloHalvor NaessUlrike Waje-AndreassenAnne AamodtRagnar SolhoffChristian LundHåkon TobroOle RønningRolf SalvesenTitto IdiculaLars Thomassen Source Type: research

HEart and BRain interfaces in Acute ischemic Stroke (HEBRAS) – rationale and design of a prospective oberservational cohort study
DiscussionBy comparing the results of routine diagnostic care to the study-specific MRI/ECG approach, the primary outcome of HEBRAS is the proportion of stroke patients with pathologic diagnostic findings. Predefined secondary outcomes are the association of stroke localization, autonomic dysbalance and cardiac dysfunction as well as the effect of impaired heart-rate-variability on long-term clinical outcome.The investigator-initiated HEBRAS study will assess whether an enhanced MRI approach and a prolonged ECG monitoring yield a higher rate of pathological findings than current standard diagnostic care to determine stroke...
Source: BMC Neurology - October 22, 2015 Category: Neurology Authors: Karl HaeuslerUlrike GrittnerJochen FiebachMatthias EndresThomas KrauseChristian Nolte Source Type: research

Severe carotid artery stenosis evaluated by ultrasound is associated with post stroke vascular cognitive impairment
ConclusionsThese findings indicate that high‐grade stenosis of carotid artery is positively correlated with post stroke VCI in patients with acute ischemic stroke. The evaluation of 1 year post stroke cognitive function may be a potential tool for screening stroke patients at risk of VCI. In conclusion, we demonstrated that high‐grade carotid artery stenosis was associated with post stroke cognitive dysfunction in patients with acute ischemic stroke and this relationship persisted even after adjusting for potential confounders.
Source: Brain and Behavior - November 21, 2016 Category: Neurology Authors: Xuefeng Li, Xiangling Ma, Jing Lin, Xiangqin He, Feng Tian, Dongmei Kong Tags: Original Research Source Type: research

Neuroimaging and Blood Biomarkers in Functional Prognosis after Stroke.
CONCLUSION: Although some biomarkers and neuroimaging techniques have potential predictive value, none of the studies were able to support its use, alone or in association, as a clinically useful functionality predictor model. All the evaluated markers were considered insufficient to predict functional prognosis at three months, when applied in the first hours after stroke. Additional studies are necessary to identify reliable predictive markers for functional prognosis after ischemic stroke. PMID: 28229841 [PubMed - in process]
Source: Acta Medica Portuguesa - February 25, 2017 Category: Journals (General) Tags: Acta Med Port Source Type: research

Platelet bio-nanobubbles as microvascular recanalization nanoformulation for acute ischemic stroke lesion theranostics
Conclusions: In summary, platelet membrane-based nanobubbles for targeting acute ischemic lesions were developed as microvascular recanalization nanoformulation for acute ischemic stroke lesion theranostics. This biomimetic PNBs theranostic strategy will be valuable for ischemic stroke patients in the future.
Source: Theranostics - December 7, 2018 Category: Molecular Biology Authors: Mingxi Li, Yang Liu, Jinpeng Chen, Taotao Liu, Zhuxiao Gu, Jianqiong Zhang, Xiaochun Gu, Gaojun Teng, Fang Yang, Ning Gu Tags: Research Paper Source Type: research

Gait speed and spasticity are independently associated with estimated failure load in the distal tibia after stroke: an HR-pQCT study
ConclusionThe paretic distal tibia showed more compromised vBMD, cortical area, cortical thickness, and estimated failure load than the non-paretic tibia. Gait speed and spasticity were independently associated with estimated failure load. As treatment programs focusing on these potentially modifiable stroke-related impairments are feasible to administer, future studies are needed to determine the efficacy of such intervention strategies for improving bone strength in individuals with chronic stroke.
Source: Osteoporosis International - October 12, 2021 Category: Orthopaedics Source Type: research

Consistencies and Differences in Intermediate Physiological Phenotypes of Vascular Ageing between Ischaemic Stroke Aetiologies
Conclusions: Intermediate cardiovascular phenotypes of vascular ageing had similar demographic associations between stroke aetiologies, but these were particularly strong in patients with small vessel stroke under the age of 65, implying a potential role of these phenotypes in increasing stroke risk in this patient group.Cerebrovasc Dis
Source: Cerebrovascular Diseases - August 23, 2022 Category: Neurology Source Type: research

Tissue Window in Stroke Thrombolysis Study (TWIST): A Safety Study.
Conclusions: Patients who awake with their deficits can be safely treated with thrombolysis based upon a tissue window defined by NCCT and CTA/TCD. PMID: 23250122 [PubMed - in process]
Source: The Canadian Journal of Neurological Sciences - January 1, 2013 Category: Neurology Authors: Hill MD, Kenney C, Dzialowski I, Boulanger JM, Demchuk AM, Barber PA, Watson TW, Weir NU, Buchan AM Tags: Can J Neurol Sci Source Type: research

Outcome of 312 Japanese Patients with Carotid Endarterectomy and Factors Associated with Cardiovascular Events—A Single-center Study in Japan
Background: There have only been a few reports regarding the outcomes and risk factors after CEA. To clarify the factors associated with outcome in patients with carotid stenosis who underwent carotid endarterectomy (CEA), we investigated cardiovascular events and mortality in the Kyushu Medical Center in Japan.Methods: We consecutively registered patients with significant carotid stenosis who had CEA performed over 10 years and compared the incidences of stroke, myocardial infarction, and death. On admission, we evaluated medical records for stroke risk factors, including hypertension, diabetes mellitus, hypercholesterol...
Source: Journal of Stroke and Cerebrovascular Diseases - May 30, 2013 Category: Neurology Authors: Toshiyasu Ogata, Tooru Inoue, Yasushi Okada Tags: Original Articles Source Type: research

Prognostic significance of carotid and vertebral ultrasound in ischemic stroke patients
ConclusionsIn stroke patients, carotid stenoses ≥60%, ipsi‐ or contralateral to cerebral lesions, were associated with an increased medium and long‐term probability of dependency or death, and abnormalities of vertebrobasilar flow were a significant indicator of death risk, independent of stroke severity and age. The medium and long‐term prognostic implications of carotid and vertebral ultrasound in ischemic stroke patients are not yet known. In 309 stroke patients we found that carotid stenoses ≥60%, ipsi‐ or contralateral to cerebral lesions, were associated with an increased medium and long‐term probabili...
Source: Brain and Behavior - March 31, 2016 Category: Neurology Authors: Antonio Muscari, Andrea Bonfiglioli, Donatella Magalotti, Giovanni M. Puddu, Veronica Zorzi, Marco Zoli Tags: Original Research Source Type: research

Risk factors between intracranial-extracranial atherosclerosis and anterior-posterior circulation stroke in ischaemic stroke.
CONCLUSION: Risk factors are different between ICAS and ECAS, ACS and PCS, and ICAS/ECAS with ACS/PCS. Thus, targeted strategies are needed to consider these differences to prevent, treat and manage these diseases. PMID: 27796172 [PubMed - as supplied by publisher]
Source: Neurological Research - November 1, 2016 Category: Neurology Tags: Neurol Res Source Type: research

Failed Removal of Indwelling Urinary Catheters in Acute Stroke Patients: Incidence and Risk Factors
Conclusions This single site study identified a high incidence of failed urinary catheter removal in stroke patients, along with factors associated with failed removal. This is the first step in developing a predictive model that could reduce the incidence of this adverse event. Policies, penalties and protocols designed to reduce catheter days must be sensitive to the special situations where IUCs are medically necessary and equal consideration given to identifying the patients for which catheter removal poses a greater risk than continued catheter use.
Source: PMandR - July 8, 2017 Category: Rehabilitation Source Type: research