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Answer to Case 684
Answer to theParasite Case of the Week 684: Anisakid L3 larvaeThe following is our third and final discussion from our amazing guest author and 3rd year medical student, Hadel Go. I ' m sure you will all agree that her discussions have been among the best we ' ve ever had on this blog. Congratulations on the excellent work, Hadel!_____________________ Worm cases are always my favorite because the comments are either “They are so beautiful!!” (@Parasite_Power on Twitter) or “…That’s a wholelottanope” (Valmik in the comments).This is a nematode in the Anisakidae family, likelyPseudoterranovaorAnisakis spp., ...
Source: Creepy Dreadful Wonderful Parasites - May 30, 2022 Category: Parasitology Source Type: blogs

Making telemedicine more inclusive
As a primary care physician at an academic community health care system in Massachusetts, I received a rapid introduction to telehealth this year. Within days after Massachusetts declared a state of emergency in response to the spread of COVID-19, almost all of our patient visits became telemedicine visits. Our staff reached out to patients to inform them of different ways they could get in touch with their doctor. Many would be able to gain access to health care through a health app connected to their healthcare web portal, or through a phone call or video call. The enormous potential of telehealth was apparent to me with...
Source: Harvard Health Blog - July 3, 2020 Category: Consumer Health News Authors: Meera Sunder, MBBS, MRCOG Tags: Coronavirus and COVID-19 Health Health care disparities Health trends Source Type: blogs

Vaccines, Antibodies and Drug Libraries. The Possible COVID-19 Treatments Researchers Are Excited About
In early April, about four months after a new, highly infectious coronavirus was first identified in China, an international group of scientists reported encouraging results from a study of an experimental drug for treating the viral disease known as COVID-19. It was a small study, reported in the New England Journal of Medicine, but showed that remdesivir, an unapproved drug that was originally developed to fight Ebola, helped 68% of patients with severe breathing problems due to COVID-19 to improve; 60% of those who relied on a ventilator to breathe and took the drug were able to wean themselves off the machines after 18...
Source: TIME: Health - April 14, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

Analysis of lactose intolerance in students with suggestive symptoms of irritable bowel syndrome
CONCLUSION: In view of the test sample quantity (n=21), a high prevalence of lactose intolerance (6.8%) in the academic environment, with epidemiological characteristics compatible to those found the literature is demonstrated, generating knowledge with understanding to prevent, diagnose, alleviate and treat lactose intolerant university students, and generate positive impacts towards well-being, improving the quality of life of these individuals.RESUMO CONTEXTO: A s índrome do intestino irritável é uma condição clínica que cursa com dor, distensão e plenitude abdominal, diarreia, constipação, entre outros sintoma...
Source: Arquivos de Gastroenterologia - September 30, 2019 Category: Gastroenterology Source Type: research

Auranofin, an Anti-rheumatic Gold Drug, Aggravates the Radiation-Induced Acute Intestinal Injury in Mice
Conclusion In this study, we found that a non-toxic dose of auranofin significantly aggravated the severity of the radiation-induced intestinal injury. This suggests that auranofin treatment can be an independent factor that influences the risk of intestinal complications after pelvic or abdominal radiotherapy. Ethics Statement All the protocols used in this study were approved by the Institutional Animal Care and Use Committee of the Korean Institute of Radiological and Medical Sciences (IACUC permit number: KIRAMS217-0007). Author Contributions H-JL, JS, and Y-BL designed the experiments. EL and JK conducted the exp...
Source: Frontiers in Pharmacology - April 23, 2019 Category: Drugs & Pharmacology Source Type: research

Group 2 Innate Lymphoid Cells Are Redundant in Experimental Renal Ischemia-Reperfusion Injury
In this study, we sought to further characterize ILC2s in the kidney, their location within this organ and determine their functional role in IRI using a loss-of-function approach. Here, we found that kidney ILC2s constitutively express IL-5 and are primarily located in close proximity to the renal vasculature, within the adventitia. Additionally, we demonstrate that a reduction, deficiency or depletion of ILC2s had minimal impact on the severity of IRI. Whilst activation of ILC2s and the associated amplification of local type 2 immunity has been previously shown to reduce the deleterious consequences of AKI, our results r...
Source: Frontiers in Immunology - April 15, 2019 Category: Allergy & Immunology Source Type: research

Potent Inhibition of Zika Virus Replication by Aurintricarboxylic Acid
In this study, we evaluated ATA as a potential antiviral drug against ZIKV replication. The antiviral activity of ATA against ZIKV replication in vitro showed median inhibitory concentrations (IC50) of 13.87 ± 1.09 μM and 33.33 ± 1.13 μM in Vero and A549 cells, respectively; without showing any cytotoxic effect in both cell lines (median cytotoxic concentration (CC50)> 1,000 μM). Moreover, ATA protected both cell types from ZIKV-induced cytopathic effect (CPE) and apoptosis in a time- and concentration-dependent manner. In addition, pre-treatment of Vero cells with ATA for up to 72 h also...
Source: Frontiers in Microbiology - April 11, 2019 Category: Microbiology Source Type: research

A Bidirectional Label Propagation Based Computational Model for Potential Microbe-Disease Association Prediction
Discussion There are numerous microbial communities inhabited in the human body, which is critical to human health. The relationship between human microbiome and diseases received much attention from both medical and bioinformatics community recently. However, traditional methods to detect their association is costly and labor-intensive. Thus, we proposed here a new computational model called NBLPIHMDA to infer potential microbe-disease associations. NBLPIHMDA first combined known microbe-disease associations in HMDAD and the Gaussian interaction profile kernel similarity to construct disease similarity network and microb...
Source: Frontiers in Microbiology - April 8, 2019 Category: Microbiology Source Type: research

… And an aphid in a peach tree!
12: Drummers Drumming (in the right chairs) On top of high levels of concentration, musical performance places significant physical stress on the body. Strength in limb muscles needed for fast complex movements, while core muscles handle the task of sustaining body position for extended durations. It is therefore no wonder that musical performance-associated musculoskeletal disorders (MSD) are a common medical issue among professional musicians, with some studies indicating that around 80% – 97% of orchestral musicians suffer from muscle pain related to musical performance. With MSDs presenting such a big threat to m...
Source: BioMed Central Blog - December 19, 2017 Category: General Medicine Authors: Davy Falkner Tags: Biology Health Medicine Avian Research BMC Ecology Frontiers in Zoology Genetics Selection Evolution Genome Biology Health Research Policy and Systems ISRCTN registry Journal of Occupational Medicine and Toxicology Lipids in Health a Source Type: blogs

Spreading Hope for Depression Through Adventure Racing
Depression is a common bond. It brings people to me that inspire me in ways I never thought possible. Shawn Beardon is one of those people. Shawn reached out to me via my foundation, iFred, and asked if we could work together raising awareness for mental health issues while making a dream of his come true. As iFred has big dreams of teaching hope around the world, it seemed like a perfect partnership. What he is about to attempt is mind blowing, as those with depression know during our darkest days, what he is trying to accomplish is probably the last thing we would ever imagine doing. If you know of any major brand sponso...
Source: World of Psychology - April 3, 2017 Category: Psychiatry & Psychology Authors: Kathryn Goetzke Tags: Depression hope Hope2017 Ifred letstalk Mental Health Shawn Beardon Source Type: blogs