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Drug: Acetic Acid

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Total 4747 results found since Jan 2013.

Protein Profile of Acetobacter pasteurianus HSZ3-21.
In this study, we utilized the proteomic approach to analyze the proteomic profile of A. pasteurianus HSZ3-21, and 258 proteins were successfully identified by MALDI-TOF-MS and database search. The hydropathy and GO analyse combined with COG results of the identified proteins revealed the molecular biological characteristics of A. pasteurianus proteins, that is, most proteins of A. pasteurianus were related to metabolic process, binding, catalytic or cellular response. Meanwhile, our results also showed that some proteins of A. pasteurianus may be responsible for acetic acid tolerance, thermotolerance, and stress response....
Source: Current Microbiology - February 4, 2015 Category: Microbiology Authors: Zhang Z, Ma H, Yang Y, Dai L, Chen K Tags: Curr Microbiol Source Type: research

Peptidome characterization and bioactivity analysis of donkey milk.
This study provides additional knowledge on this milk, already characterized by traditional proteomics studies and peptidomic studies after simulated digestion. This type of study is not just a description of the naturally occurring peptidome o f a sample, but also represents a starting point to discover and characterize those naturally occurring peptides responsible for the observed bioactivities of biological samples, as in the case of donkey milk, which would remain uncharacterized by other approaches. In this paper an analytical protocol was described for the efficient isolation and purification of peptides in donkey m...
Source: Journal of Proteomics - February 7, 2015 Category: Biochemistry Authors: Piovesana S, Capriotti AL, Cavaliere C, La Barbera G, Samperi R, Chiozzi RZ, Laganà A Tags: J Proteomics Source Type: research

A chemiluminescent light system in combination with toluidine blue to assess suspicious oral lesions—clinical evaluation and review of the literature
Conclusions The adjunct of TB to VL reduces the number of false positives without increasing the rate of false negatives. Clinical relevance Clinical evidence to justify the additional cost of the system for diagnosis of suspicious lesions is weak. However, for the potential role of VLP in detection of lesions not otherwise identified in the visual exam in general dental practice further studies are required.
Source: Clinical Oral Investigations - February 26, 2015 Category: Dentistry Source Type: research

D-002 (beeswax alcohols): Concurrent joint health benefits and gastroprotection
Vivian Molina, R Mas, D CarbajalIndian Journal of Pharmaceutical Sciences 2015 77(2):127-134Nonsteroidal antiinflammatory drugs include the traditional drugs and more selective COX-2 inhibitors. Traditional nonsteroidal antiinflammatory drug use is hampered by their gastrotoxicity, while COX-2-inhibitors increase the cardiovascular risk. The search of safer substances for managing inflammatory conditions is updated, a challenge wherein dual COX/5-LOX inhibitors have a place. This review summarizes the benefits of D-002, a mixture of higher aliphatic beeswax alcohols, on joint health and gastric mucosa. D-002 elicits gastro...
Source: Indian Journal of Pharmaceutical Sciences - May 7, 2015 Category: Drugs & Pharmacology Authors: Vivian MolinaR MasD Carbajal Source Type: research

Dissecting the role of two cytokinin analogues (INCYDE and PI-55) on in vitro organogenesis, phytohormone accumulation, phytochemical content and antioxidant activity
Publication date: Available online 5 June 2015 Source:Plant Science Author(s): Adeyemi O. Aremu , Wendy A. Stirk , Nqobile A. Masondo , Lenka Plačková , Ondřej Novák , Aleš Pěnčík , Marek Zatloukal , Jaroslav Nisler , Lukáš Spíchal , Karel Doležal , Jeffrey F. Finnie , Johannes Van Staden There is a continuous search for new chemical entities to expand the collection of suitable compounds to increase the efficiency of micropropagation protocols. Two cytokinin (CK) analogues, 2-chloro-6-(3-methoxyphenyl)aminopurine (INCYDE) and CK antagonist 6-(2-hydroxy-3-methylbenzylamino)purine (PI-55) were used as a tool t...
Source: Plant Science - June 5, 2015 Category: Biology Source Type: research

Determination of corrosion inhibition effects of amino acids: Quantum chemical and molecular dynamic simulation study
Publication date: Available online 27 June 2015 Source:Journal of the Taiwan Institute of Chemical Engineers Author(s): Savaş Kaya , Burak Tüzün , Cemal Kaya , Ime Bassey Obot Amino acids are biologically important organic compounds in the human body which contain two important functional groups namely: –NH2 (amine) and –COOH (carboxylic acid) in their structures. In the present work, corrosion inhibitive performance amino acids such alanine (Ala), methionine (Met), aspartate (Asp), asparagine (Asn), lysine (Lys), arginine (Arg) and histidine (His) were investigated. All quantum chemical calculations related to th...
Source: Journal of the Taiwan Institute of Chemical Engineers - June 27, 2015 Category: Chemistry Source Type: research

Mitochonic Acid 5 (MA-5), a Derivative of the Plant Hormone Indole-3-Acetic Acid, Improves Survival of Fibroblasts from Patients with Mitochondrial Diseases.
T, Tomioka Y, Toyomizu M, Ito S, Osaka H, Hayashi K, Abe T Abstract Mitochondria are key organelles implicated in a variety of processes related to energy and free radical generation, the regulation of apoptosis, and various signaling pathways. Mitochondrial dysfunction increases cellular oxidative stress and depletes ATP in a variety of inherited mitochondrial diseases and also in many other metabolic and neurodegenerative diseases. Mitochondrial diseases are characterized by the dysfunction of the mitochondrial respiratory chain, caused by mutations in the genes encoded by either nuclear DNA or mitochondrial DNA...
Source: The Tohoku Journal of Experimental Medicine - July 1, 2015 Category: Research Authors: Suzuki T, Yamaguchi H, Kikusato M, Matsuhashi T, Matsuo A, Sato T, Oba Y, Watanabe S, Minaki D, Saigusa D, Shimbo H, Mori N, Mishima E, Shima H, Akiyama Y, Takeuchi Y, Yuri A, Kikuchi K, Toyohara T, Suzuki C, Kohzuki M, Anzai J, Mano N, Kure S, Yanagisawa Tags: Tohoku J Exp Med Source Type: research

Diagnostic accuracy of serum cystatin C in chronic kidney disease: a meta-analysis.
CONCLUSION: SCysC appears to be a good biomarker in the definition of CKD. However, its performance is different in subgroups restricted by clinical settings, race, and sCysC assay. PMID: 26200185 [PubMed - as supplied by publisher]
Source: Clinical Nephrology - July 24, 2015 Category: Urology & Nephrology Authors: Wei L, Ye X, Pei X, Wu J, Zhao W Tags: Clin Nephrol Source Type: research

Systematic reviews and meta-analyses of the accuracy of HPV tests, visual inspection with acetic acid, cytology, and colposcopy
Conclusions Although differences in sensitivity between tests could be interpreted as large, absolute differences in missed diagnoses were small. By contrast, small differences in specificity resulted in fairly large absolute differences in overtreatment.
Source: International Journal of Gynecology and Obstetrics - November 12, 2015 Category: OBGYN Source Type: research

Plant growth promoting Burkholderia species isolated from annual ryegrass in Portuguese soils
ConclusionsThis work revealed that annual ryegrass can naturally associate with members of the genus Burkholderia. A novel plant growth promoting strain of B. graminis was obtained. Significance and Impact of the StudyThe novel strain belongs to the plant‐associated Burkholderia cluster and is a promising candidate for exploitation as plant inoculant in field conditions.This article is protected by copyright. All rights reserved.
Source: Journal of Applied Microbiology - December 16, 2015 Category: Microbiology Authors: N. Castanheira, A.C. Dourado, S. Kruz, P.I.L. Alves, A.I. Delgado‐Rodríguez, I. Pais, J. Semedo, P. Scotti‐Campos, C. Sánchez, N. Borges, G. Carvalho, M.T. Barreto Crespo, P. Fareleira Tags: Original Article Source Type: research

Search for genes responsible for the remarkably high acetic acid tolerance of a Zygosaccharomyces bailii-derived interspecies hybrid strain
Conclusions: ISA1307 genes homologous to S. cerevisiae genes GYP8, WSC4, PMT1, KTR7, RKR1, TIF3, ILV3 and MSN4 are proposed as strong candidate determinants of acetic acid tolerance. The ORF ZBAI_02295 that contains a functional domain associated to the uncharacterised integral membrane proteins of unknown function of the DUP family is also suggested as a relevant tolerance determinant. The genes ZbMSN4 and ZbTIF3, encoding a putative stress response transcription factor and a putative translation initiation factor, were confirmed as determinants of acetic acid tolerance in both Z. bailii and S. cerevisiae. This study prov...
Source: BMC Genomics - December 16, 2015 Category: Genetics & Stem Cells Authors: Margarida PalmaFilipa RoqueJoana GuerreiroNuno MiraLise QueirozIsabel Sá-Correia Source Type: research

Validation of a predictive model for fed-batch and continuous lipids production processes from acetic acid using the oleaginous yeast Cryptococcus curvatus
This study focuses on the use of acetic acid as carbon source for cell mass and lipid production using an oleaginous yeast, Cryptococcus curvatus. To improve this cell mass and lipid production on acetic acid, a numerical model was built to predict the yeast behaviour. The model was first calibrated and validated on a fed-batch culture of the oleaginous yeast grown on acetic acid. After the validation step, this model was used as a predictive tool to search for optimal dilution rate and C/N ratios for continuous culture. A continuous culture was then launched using these culture parameters, revealing that the experimental ...
Source: Biochemical Engineering Journal - January 24, 2016 Category: Biochemistry Source Type: research

The Role of the Microbial Environment in Drosophila Post-Embryonic Development.
Abstract Development, growth and maturation of animals are under genetic and environmental control. Multicellular organisms interact throughout their lives with a variety of environment- and body-associated microorganisms. It has now been appreciated that the very conspicuous and varied microbial population associated with the food and the gastro-intestinal tract is a critical factor that can influence growth. Beyond the phenomenology, the mechanisms underlying the beneficial effects of microbes on development are being revealed from studies in Drosophila melanogaster, a particularly well suited system for a mecha...
Source: Developmental and Comparative Immunology - January 28, 2016 Category: Allergy & Immunology Authors: Strigini M, Leulier F Tags: Dev Comp Immunol Source Type: research

Plant growth‐promoting Burkholderia species isolated from annual ryegrass in Portuguese soils
ConclusionsThis work revealed that annual ryegrass can naturally associate with members of the genus Burkholderia. A novel plant growth promoting strain of B. graminis was obtained. Significance and Impact of the StudyThe novel strain belongs to the plant‐associated Burkholderia cluster and is a promising candidate for exploitation as plant inoculant in field conditions.
Source: Journal of Applied Microbiology - February 9, 2016 Category: Microbiology Authors: N. Castanheira, A.C. Dourado, S. Kruz, P.I.L. Alves, A.I. Delgado‐Rodríguez, I. Pais, J. Semedo, P. Scotti‐Campos, C. Sánchez, N. Borges, G. Carvalho, M.T. Barreto Crespo, P. Fareleira Tags: Original Article Source Type: research

Electrotherapy modalities for rotator cuff disease.
CONCLUSIONS: Based on low quality evidence, therapeutic ultrasound may have short-term benefits over placebo in people with calcific tendinitis, and LLLT may have short-term benefits over placebo in people with rotator cuff disease. Further high quality placebo-controlled trials are needed to confirm these results. In contrast, based on low quality evidence, PEMF may not provide clinically relevant benefits over placebo, and therapeutic ultrasound, LLLT and PEMF may not provide additional benefits when combined with other physical therapy interventions. We are uncertain whether TENS is superior to placebo, and whether any ...
Source: Cochrane Database of Systematic Reviews - June 9, 2016 Category: Journals (General) Authors: Page MJ, Green S, Mrocki MA, Surace SJ, Deitch J, McBain B, Lyttle N, Buchbinder R Tags: Cochrane Database Syst Rev Source Type: research