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Procedure: Liver Transplant

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Total 226 results found since Jan 2013.

Asthma, Eczema, and Food Allergy in Children Following Liver Transplantation
To describe the prevalence and the relationship between asthma, eczema, food allergy, and rhinitis in children after liver transplantation.
Source: The Journal of Pediatrics - September 27, 2018 Category: Pediatrics Authors: Runar Almaas, Svanhildur Haflidadottir, Runa Helen Kaldestad, Iren Lindbak Matthews Tags: Original Articles Source Type: research

A single-center experience of post-transplant lymphoproliferative disorder (PTLD) cases after pediatric liver transplantation: Incidence, outcomes, and association with food allergy.
CONCLUSION: PTLD is a life-threatening complication of solid-organ transplantation with a heterogeneous clinical spectrum. Food allergy had a close association with PTLD. A close follow-up of patients with risk factors and an early diagnosis with appropriate treatment may lead to a better outcome. PMID: 29755021 [PubMed - in process]
Source: The Turkish Journal of Gastroenterology - May 1, 2018 Category: Gastroenterology Authors: Barış Z, Özçay F, Yılmaz Özbek Ö, Haberal N, Sarıalioğlu F, Haberal M Tags: Turk J Gastroenterol Source Type: research

Abstract 246: Single Center Study of Statin Use Among Renal Transplant Recipients Session Title: Poster Session PM
Conclusion: In this high risk cohort, a significant proportion of patients who were statin eligible including diabetics, were not prescribed statin. Less than half of renal transplant recipients had a lipid panel documented pre and post- transplant. Patterns of use of cardioprotective medications in the renal transplant population, and its relation to renal and cardiac outcomes needs further study.
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Nestasie, M., Madhana Kumar, A., Doyle, M., Poornima, I. G. Tags: Session Title: Poster Session PM Source Type: research

Increase of natural killer cells in children with liver transplantation-acquired food allergy.
CONCLUSIONS: This study confirms that liver-transplant children treated with tacrolimus alone have a higher risk of developing TAFA than kidney-transplant children treated with tacrolimus plus mycophenolate. NK cells might be involved in this difference. PMID: 29456038 [PubMed - as supplied by publisher]
Source: Allergologia et Immunopathologia - February 15, 2018 Category: Allergy & Immunology Authors: Mori F, Angelucci C, Cianferoni A, Barni S, Indolfi G, Casini A, Mangone G, Materassi M, Pucci N, Azzari C, Novembre E Tags: Allergol Immunopathol (Madr) Source Type: research

Post-transplantation Development of Food Allergies
AbstractPurpose of ReviewThe development of food allergies is increasingly being recognized as a post-solid organ transplant complication. In this article, we review the spectrum of post-transplant food allergy development and the proposed mechanisms for de novo food allergies and the clinical significance they pose.Recent FindingsThe development of new food allergies is disproportionately associated with pediatric liver transplants, where it occurs in up to 38% of select populations. The mechanism of food allergy development is not completely understood; however, it is likely promoted by unbalanced immune suppression.Summ...
Source: Current Allergy and Asthma Reports - January 29, 2018 Category: Allergy & Immunology Source Type: research

What is DIOS?
Discussion Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in the cystic fibrosis transmembrane receptor (CFTR). It is found in the epithelium of the bronchi, intestine, pancreatic duct and biliary tree. It regulates chloride, bicarbonate and water secretion. The heterozygous state helps prevent against secretory diarrhea, but the homozygous state causes thickened secretions in the hollow tubes of the lungs and digestive tract. There are multiple mutations (> 2000) which have been currently classified into classes depending on their protein production and activity. CF patients generally are l...
Source: PediatricEducation.org - December 18, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Necrotizing enterocolitis in the setting of milk allergy after pediatric living donor liver transplantation
Abstract NEC is an idiopathic intestinal mucosal injury that may progress to transmural bowel necrosis without mesenteric ischemia. NEC usually affects 7‐ to 10‐day‐old neonates following enteral feeding. A 10‐month‐old girl with no history of laparotomy underwent LDLT for acute liver failure. After starting enteral feeding on postoperative day 5, she developed abdominal distention. Diffuse PVG and PI were detected by radiologic modalities. Exploratory laparotomy revealed patchy necrosis of the intestine without perforation. The microscopic findings of a resected specimen revealed transmural coagulative necrosis ...
Source: Pediatric Transplantation - December 1, 2017 Category: Transplant Surgery Authors: Soichi Narumoto, Seisuke Sakamoto, Hajime Uchida, Kengo Sasaki, Takanobu Shigeta, Akinari Fukuda, Shunsuke Nosaka, Rie Irie, Takako Yoshioka, Mureo Kasahara Tags: CASE REPORT Source Type: research

Geoepidemiology of Primary Biliary Cholangitis: Lessons from Switzerland
AbstractNo data on primary biliary cholangitis (PBC) are available in Switzerland. We established a national patient cohort to obtain information on PBC phenotypes and disease course in Switzerland. Local databases in all university hospitals and in two large secondary centers were searched for case finding. In addition, all primary care physicians, gastroenterologists, rheumatologists, and dermatologists were invited to contribute patients from their own medical records. PBC diagnosis was centrally reviewed. Five hundred one PBC patients were identified, 474 were included in data analysis, and 449 of them were enrolled by...
Source: Clinical Reviews in Allergy and Immunology - November 27, 2017 Category: Allergy & Immunology Source Type: research

Common Variable Immunodeficiency and Liver Involvement
AbstractCommon variable immunodeficiency (CVID) is a primary B-cell immunodeficiency disorder, characterized by remarkable hypogammaglobulinemia. The disease can develop at any age without gender predominance. The prevalence of CVID varies widely worldwide. The underlying causes of CVID remain largely unknown; primary B-cell dysfunctions, defects in T cells and antigen-presenting cells are involved. Although some monogenetic defects have been identified in some CVID patients, it is likely that CVID is polygenic. Patients with CVID develop recurrent and chronic infections (e.g., bacterial infections of the respiratory or ga...
Source: Clinical Reviews in Allergy and Immunology - August 7, 2017 Category: Allergy & Immunology Source Type: research

Graded isavuconazole introduction in a patient with voriconazole allergy
This article is protected by copyright. All rights reserved.
Source: Transplant Infectious Disease - August 1, 2017 Category: Transplant Surgery Authors: Megan K. Morales, Ch é Harris, Shmuel Shoham Tags: Case Report Source Type: research

Liver disease predicts mortality in patients with XHIM but can be prevented by early hematopoietic stem cell transplantation
In the largest detailed study of liver disease in X-linked immunodeficiency with hyper-IgM, we show that liver disease is commoner than generally recognized and that early hematopoietic stem cell transplantation may prevent liver disease progression and improve survival.
Source: Journal of Allergy and Clinical Immunology - July 26, 2017 Category: Allergy & Immunology Authors: Vian Azzu, Lucinda Kennard, Beatriz Morillo-Gutierrez, Mary Slatter, J.David M. Edgar, Dinakantha S. Kumararatne, William JH. Griffiths Source Type: research

Liver disease predicts mortality in patients with X-linked immunodeficiency with hyper-IgM but can be prevented by early hematopoietic stem cell transplantation
X-linked immunodeficiency with hyper-IgM (XHIM) is a severe primary immunodeficiency disorder characterized by low levels of, or absence of IgG, IgA, and IgE, with normal to raised serum IgM concentrations.1 XHIM results from mutations in the CD40 ligand (CD40L) gene found on activated CD4 T cells2; disruption of this gene results in aberrant interaction with CD40 on B-cell membranes, thus inhibiting B-cell proliferation and immunoglobulin class switching.3 CD40 is also found on other cells such as monocytes and endothelial and epithelial cells.
Source: Journal of Allergy and Clinical Immunology - July 26, 2017 Category: Allergy & Immunology Authors: Vian Azzu, Lucinda Kennard, Beatriz Morillo-Gutierrez, Mary Slatter, J. David M. Edgar, Dinakantha S. Kumararatne, William J.H. Griffiths Tags: Letter to the Editor Source Type: research

Conversion From Once-Daily Prolonged-Release Tacrolimus to Once-Daily Extended-Release Tacrolimus in Stable Liver Transplant Recipients.
CONCLUSIONS: Conversion from prolonged-release to extended-release tacrolimus in stable liver transplant patients is safe and cost-effective; however, initially, dose adaptations and careful monitoring are required. PMID: 28697715 [PubMed - as supplied by publisher]
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - July 11, 2017 Category: Transplant Surgery Authors: Altieri M, Delaval G, Kimmoun E, Allaire M, Salamé E, Dumortier J Tags: Exp Clin Transplant Source Type: research

Factors Associated with Development of Food Allergy in Young Children after Liver Transplantation: A Retrospective Analysis of 10  Years' Experience
Conclusions We identified eczema at liver transplantation as a significant risk factor for the development of IgE-mediated food allergy after liver transplantation, but not non–IgE-mediated food allergy. Our findings may contribute to a better understanding of the susceptible subgroup requiring special caution and to the establishment of effective strategies for prevention.
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 24, 2017 Category: Allergy & Immunology Source Type: research

How Common is α -1-Antitrypsin Deficiency?
Discussion α-1-Antitrypsin Deficiency (A1AT) is a common single-gene mutation disease that is homozygous recessive. The normal allele is called M and the most common abnormal allele is Z. There are other alleles though. The gene codes for one of the primary protease inhibitors in the serum, thus those who are homozygous for the Z gene are sometimes referred to as “PIZZ” or “PIZ.” α-1-Antitrypsin is found in all body tissues but is especially important in the serum and lung. As noted it is one of the primary neutrophil protease inhibitors in the serum, and acts to neutralize these enzymes...
Source: PediatricEducation.org - April 24, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news