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Nutrition: Wheat
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Wheat-Dependent Exercise-Induced Anaphylaxis
Opinion statementWheat-dependent exercise-induced anaphylaxis (WDEIA) is presently gaining attention. Patients with WDEIA experience allergic symptoms when they exercise following wheat consumption. Some patients may be advised to restrict wheat consumption or exercise because of repeated allergic symptoms without adequate diagnosis or examination. Japanese guidelines recommend that WDEIA should be diagnosed using provocation tests with wheat and exercise. After wheat consumption, patients exercise using a treadmill or an ergometer during provocation tests. Once WDEIA is diagnosed, patients should not consume wheat before ...
Source: Current Treatment Options in Allergy - June 1, 2017 Category: Allergy & Immunology Source Type: research
Antibody reactivity in patients with IgE-mediated wheat allergy to various subunits and fractions of gluten and non-gluten proteins from ω-gliadin-free wheat genotypes.
CONCLUSION: [/b] The observed differentiation of immunodetection spectra allows to model highly specific IgE-binding profiles of allergenic wheat proteins attributed to individual patients with symptoms of gluten intolerance. Highly immunoreactive subunits and fractions among GP and NGP were identified. The observed immunoreactivity of 49 kDa NGP is worth to emphasize, as it has never been reported as wheat allergenic protein before.
PMID: 28664699 [PubMed - in process]
Source: Annals of Agricultural and Environmental Medicine : AAEM - May 11, 2017 Category: Environmental Health Authors: Skoczowski A, Obtułowicz K, Czarnobilska E, Dyga W, Mazur M, Stawoska I, Waga J Tags: Ann Agric Environ Med Source Type: research
Follow ‐up of patients with uncertain symptoms during an oral food challenge is useful for diagnosis
ConclusionsMonitoring of recurring symptoms following consumption of causative foods at home by patients with uncertain symptoms improve the diagnostic accuracy of an Open‐OFC.This article is protected by copyright. All rights reserved.
Source: Pediatric Allergy and Immunology - October 19, 2017 Category: Allergy & Immunology Authors: Taro Miura, Noriyuki Yanagida, Sakura Sato, Kiyotake Ogura, Motohiro Ebisawa Tags: Original Source Type: research
A history into genetic and epigenetic evolution of food tolerance: how humanity rapidly evolved by drinking milk and eating wheat
Purpose of review: Human exposure to wheat and milk is almost global worldwide. Yet the introduction of milk and wheat is very recent (5000–10 000 years) when compared to the human evolution. The last 4 decades have seen a rise in food allergy and food intolerance to milk and wheat. Often described as plurifactorial, the cause of allergic diseases is the result from an interplay between genetic predisposition and epigenetic in the context of environmental changes.
Recent findings: Genetic and epigenetic understanding and their contribution to allergy or other antigen-driven diseases have considerably advanced in the l...
Source: Current Opinion in Allergy and Clinical Immunology - October 25, 2017 Category: Allergy & Immunology Tags: Special Commentaries Source Type: research
Occupational Asthma due to Food Allergy in a Madagascan Cook
Conclusions: As restaurant cook, the patient had had to taste milk containing dishes up to 200 x per working day. Since he hadn't been exposed to cow milk before entering the job we concluded, that the food allergy and asthma had been caused by his occupation. To our knowledge this is the first case for occupational asthma by ingestive allergens in Germany.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Bittner, C., Preisser, A. M., Harth, V. Tags: Occupational and Environmental Health Source Type: research
Exercise Lowers Threshold and Increases Severity, but Wheat-Dependent, Exercise-Induced Anaphylaxis Can Be Elicited at Rest
Conclusions A challenge test with gluten at rest and combined exercise is a safe confirmatory test for WDEIA. A reaction can be elicited at rest (without exercise), but exercise is able to lower the threshold and increase the severity.
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 7, 2018 Category: Allergy & Immunology Source Type: research
Wheat-dependent, co-factor augmented anaphylaxis; a prospective study of exercise, aspirin and alcohol efficacy as co-factors
ConclusionsOur results demonstrate that exercise and aspirin augment clinical reactions in WDEIA by lowering threshold and increase the severity of the allergic reaction, whereas alcohol gave ambiguous results. Secondly, a combination of two co-factors (exercise+aspirin) further increase the risk of reactions.
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 7, 2018 Category: Allergy & Immunology Source Type: research
A murine model of wheat versus potato allergy: Patatin and 53kDa protein are the potential allergen from potato
Publication date: September 2018Source: Molecular Immunology, Volume 101Author(s): Ibtessam Tahir Ansari, Taihua MuAbstractWheat allergy is the most common around the world as gluten is the potential allergen. People diagnosed with wheat allergy were mainly substitute with other novel food such as potato though it is also being reported for allergenic manifestations. Thus there is an increasing demand for developing a BALB/c mice model to empathize the allergic properties of potato protein and its fractions. Purified potato protein showed lower IgE-binding capacity (474.39 ± 0.6 ng/mL) even in higher concentration (...
Source: Molecular Immunology - July 19, 2018 Category: Allergy & Immunology Source Type: research
Wheat-Dependent Cofactor-Augmented Anaphylaxis: A Prospective Study of Exercise, Aspirin, and Alcohol Efficacy as Cofactors
ConclusionOur results demonstrate that exercise and aspirin augment clinical reactions in WDEIA by lowering the threshold and increase the severity of the allergic reaction, whereas alcohol gives ambiguous results. Furthermore, a combination of 2 cofactors (exercise and aspirin) increases the risk of reactions.
Source: The Journal of Allergy and Clinical Immunology: In Practice - August 17, 2018 Category: Allergy & Immunology Source Type: research
Food allergy symptoms: Nine signs that indicate you could be allergic to certain foods
FOOD allergy is when the body ’s immune system reacts to particular foods, causing a range of uncomfortable symptoms. Common food allergies are seeds, fish and wheat, so what signs indicate you could be allergic and what is involved in food allergy testing?
Source: Daily Express - Health - September 28, 2018 Category: Consumer Health News Source Type: news
Building Tolerance Helps Kids With Wheat Allergy
TUESDAY, Oct. 30, 2018 -- Giving trace amounts of wheat to children with wheat allergy shows promise in treating the allergy, according to new research.
The researchers started with 46 wheat-allergic children, average age about 9 years, and gave...
Source: Drugs.com - Daily MedNews - October 30, 2018 Category: General Medicine Source Type: news
Oral Immunotherapy Beneficial in Patients With Wheat Allergy
WEDNESDAY, Oct. 31, 2018 -- Vital wheat gluten (VWG) oral immunotherapy (OIT) induces desensitization in about half of patients with wheat allergy after a year of treatment, according to a study published online Oct. 30 in the Journal of Allergy and...
Source: Drugs.com - Pharma News - October 31, 2018 Category: Pharmaceuticals Source Type: news
Yogurt is tolerated by the majority of children with IgE-mediated cow's milk allergy.
CONCLUSIONS: The results of our study are placed alongside others already present in the literature and concerning other methods of processing CM proteins and help to reduce the dietary restrictions of the majority of children with systemic IgE-CMA.
PMID: 30573322 [PubMed - as supplied by publisher]
Source: Allergologia et Immunopathologia - December 17, 2018 Category: Allergy & Immunology Authors: Monaco S, Russo G, Romano A, Liotti L, Verga MC, Miceli Sopo S Tags: Allergol Immunopathol (Madr) Source Type: research
Allergen-specific CD8+ T cells in peanut-allergic individuals
CD8+ T cells are uncommonly thought to be involved in IgE-mediated food allergy, but there are reasons to reconsider their role in this condition.1 CD8+ T cells are present in skin, and in the respiratory and gut mucosae, where they may modulate the immune response in atopic conditions such as asthma and atopic dermatitis.2-4 In mice, CD8+ T cells attenuate food allergy in some experimental models, whereas in humans, CD8+ T cells have been shown to expand in response to wheat ingestion in celiac disease.
Source: Journal of Allergy and Clinical Immunology - January 21, 2019 Category: Allergy & Immunology Authors: Wong Yu, Xiaoying Zhou, Diane Dunham, Shu Chen Lyu, Monali Manohar, Wenming Zhang, Fan Zhao, Mark M. Davis, Kari Nadeau Tags: Letter to the Editor Source Type: research
