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Infectious Disease: Parasitic Diseases
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Total 613 results found since Jan 2013.
A rare and unusual cause of mammographic calcification in the breast
Discussion Answer: C Histologically, there are focal collections of dilated ducts and microcysts lined by vacuolated epithelium showing lactational change. Many rounded concentric calcifications of various sizes are seen within the ductal lumina. These show characteristic appearances of Liesegang rings. In some ducts, the rings surround amorphous material with histologically identifiable calcific deposits. A mild chronic inflammatory infiltrate is seen in-between ducts. Liesegang rings are spherical, ring-like structures that show a characteristic appearance of concentric laminations...
Source: Journal of Clinical Pathology - December 13, 2016 Category: Pathology Authors: Robinson, A., Shaaban, A. M. Tags: Immunology (including allergy), Breast cancer, Inflammation, Clinical diagnostic tests Virtual case of the month Source Type: research
The potential impact of gut on your health: Current status and future challenges
Our health and probably also our behaviors and mood depend not only on what we eat or what we do (lifestyle behaviors), but also on what we host. It is well established for decades that all vertebrates including humans are colonized by a wide array of bacteria, fungi, eukaryotic parasite s and viruses, and that, at steady state (homeostasis), this community of microbes establishes a friendly mutual relationship with the host. The term microbiota was originally meant to represent an ecological community of commensals and potentially pathogenic microbes that live within our bodies, bu t it is now used interchange...
Source: Asian Pacific Journal of Allergy and Immunology - December 18, 2016 Category: Allergy & Immunology Source Type: research
LJI researchers strengthen the case for sexual transmission of Zika virus
(La Jolla Institute for Allergy and Immunology) Aedes aegypti mosquitoes harboring parasitic Zika virus (ZIKV) are the primary transmitters of virus to humans, potentially causing catastrophic congenital microcephaly in babies born to women bitten by infected mosquitoes.
Source: EurekAlert! - Biology - December 20, 2016 Category: Biology Source Type: news
Coexistence of erythema dyschromicum perstans and vitiligo: a case report and review of the literature.
Authors: Tamer F
Abstract
Erythema dyschromicum perstans is a rare, chronic, pigmentary disorder with unknown etiology. It clinically presents with oval to round, gray, blue, or brown macules of various sizes. The etiology remains unknown; however, cobalt allergy, radio contrast media, intestinal parasites, human immunodeficiency virus, and hypothyroidism have been proposed as causative factors. In addition, vitiligo is characterized by depigmented macules and patches that are widely andsymmetrically distributed. It has been suggested that autoimmune mechanisms play an important role in the etiopathogenesis of viti...
Source: Acta Dermatovenerologica Alpina, Panonica, et Adriatica - December 24, 2016 Category: Dermatology Tags: Acta Dermatovenerol Alp Pannonica Adriat Source Type: research
Opisthorchis felineus negatively associates with skin test reactivity in Russia – EuroPrevall‐INCO study
ConclusionsThere is a negative association between a chronic helminth infection and skin prick test reactivity even in a developed country.This article is protected by copyright. All rights reserved.
Source: Allergy - December 29, 2016 Category: Allergy & Immunology Authors: Olga S. Fedorova, Jacqueline J. Janse, Ludmila M. Ogorodova, Marina M. Fedotova, Rogier A. Achterberg, Jaco J. Verweij, Montserrat Fern ández‐Rivas, Serge A. Versteeg, James Potts, Cosetta Minelli, Ronald van Ree, Peter Burney, Maria Yazdanbakhsh Tags: Original Article: Epidemiology and Genetics Source Type: research
Intrinsic transcriptional heterogeneity in B cells controls early class switching to IgE
In this study, we combine novel mouse reporters and single-cell RNA sequencing to reveal the heterogeneity in IL-4–induced I transcription. We identify an early population of cells expressing I but not I1 and demonstrate that early I transcription leads to switching to IgE and occurs at lower activation levels than I1. Our results reveal how probabilistic transcription with a lower activation threshold for I directs the early choice of IgE versus IgG1, a key physiological response against parasitic infestations and a mediator of allergy and asthma.
Source: The Journal of Experimental Medicine - January 1, 2017 Category: Internal Medicine Authors: Wu, Y. L., Stubbington, M. J. T., Daly, M., Teichmann, S. A., Rada, C. Tags: Genome Stability Articles Source Type: research
Opisthorchis felineus negatively associates with skin test reactivity in Russia —EuroPrevall‐International Cooperation study
ConclusionsThere is a negative association between a chronic helminth infection and skin prick test reactivity even in a developed country.
Source: Allergy - January 24, 2017 Category: Allergy & Immunology Authors: O. S. Fedorova, J. J. Janse, L. M. Ogorodova, M. M. Fedotova, R. A. Achterberg, J. J. Verweij, M. Fern ández‐Rivas, S. A. Versteeg, J. Potts, C. Minelli, R. Ree, P. Burney, M. Yazdanbakhsh Tags: Original Article Source Type: research
Investigational malaria vaccine shows considerable protection in adults in malaria season
(NIH/National Institute of Allergy and Infectious Diseases) An investigational malaria vaccine given intravenously was well-tolerated and protected a significant proportion of healthy adults against infection with Plasmodium falciparum malaria -- the deadliest form of the disease -- for the duration of the malaria season, according to new findings published in the Feb. 15th issue of the journal Lancet Infectious Diseases. The study participants live in Mali, Africa, where they are naturally exposed to the parasite.
Source: EurekAlert! - Infectious and Emerging Diseases - February 15, 2017 Category: Infectious Diseases Source Type: news
Eosinophilia associated with Strongyloides infection, severe asthma, and central bronchiectasis
The primary causative agent of human strongyloidiasis is Strongyloides stercoralis, a soil-transmitted helminth of the Strongyloides genus.1 Although strongyloidiasis characteristically occurs through contact with contaminated soil, rare cases of human transmission have also been documented.1 The nematode can be found globally; however, its prevalence is higher in tropical and subtropical regions.1 Within the United States, the highest rates of strongyloidiasis are seen in immigrants, especially those coming from Latin American countries where intestinal parasites, such as S stercoralis, are endemic.
Source: Annals of Allergy, Asthma and Immunology - February 18, 2017 Category: Allergy & Immunology Authors: Kishan Shah, Denisa Ferastraoaru, Sunit Jariwala Tags: Letter Source Type: research
AMA1-RON2 Complex-Based Vaccine Against Malaria
This technology relates to a malaria vaccine composed of a protein complex of Apical Membrane Antigen (AMA1) and rhoptry neck protein 2 (RON2) with an adjuvant. AMA1 is a crucial component of thePlasmodium invasion machinery and is a leading candidate for antimalarial vaccine development. AMA1-based vaccines have shown ability to block red cell invasion inin vitro assays, but protection has so far not translated toin vivo human infections. NIAID investigators have demonstrated that interaction between AMA1 and RON2 (or peptide thereof) is essential for malaria parasites to successfully enter human red blood cells (RBCs). V...
Source: NIH OTT Licensing Opportunities - March 9, 2017 Category: Research Authors: ajoyprabhu3 Source Type: research
Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota
Helminth parasites have been reported to have beneficial immunomodulatory effects in patients with allergic and autoimmune conditions and detrimental consequences in patients with tuberculosis and some viral infections. Their role in coinfection with respiratory viruses is not clear.
Source: Journal of Allergy and Clinical Immunology - February 11, 2017 Category: Allergy & Immunology Authors: Amanda J. McFarlane, Henry J. McSorley, Donald J. Davidson, Paul M. Fitch, Claire Errington, Karen J. Mackenzie, Eva S. Gollwitzer, Chris J.C. Johnston, Andrew S. MacDonald, Michael R. Edwards, Nicola L. Harris, Benjamin J. Marsland, Rick M. Maizels, J ü Source Type: research
The role of ST2 and ST2 genetic variants in schistosomiasis
ST2 mediates a Th2 response characteristic of both allergic and parasitic disease. We demonstrate that end-stage schistosomiasis is associated with sST2 levels and ST2 polymorphisms associated with asthma are associated with sST2 in schistosomiasis.
Source: Journal of Allergy and Clinical Immunology - February 10, 2017 Category: Allergy & Immunology Authors: Xin Long, Michelle Daya, Jianping Zhao, Nicholas Rafaels, Huifang Liang, Joseph Potee, Monica Campbell, Bixiang Zhang, Maria Ilma Araujo, Ricardo R. Oliveira, Rasika A. Mathias, Li Gao, Ingo Ruczinski, Steve N. Georas, Donata Vercelli, Terri H. Beaty, Kat Source Type: research
Efficacy and safety of a new spot-on formulation of selamectin plus sarolaner in the treatment of naturally occurring flea and tick infestations in cats presented as veterinary patients in Europe
Publication date: April 2017 Source:Veterinary Parasitology, Volume 238, Supplement 1 Author(s): Thomas Geurden, Csilla Becskei, Robert Farkas, Dan Lin, Douglas Rugg Two randomised, blinded, multi-centre field studies were conducted in Europe (Germany, Italy, France, Hungary) to demonstrate the efficacy and safety of three monthly applications of a new spot-on formulation of selamectin plus sarolaner (Stronghold® Plus, Zoetis) against natural flea or tick infestations in cats presented as veterinary patients. The spot-on formulation was administered at the commercial dose range of 6.0–12.0mg selamectin and 1.0–2.0mg ...
Source: Veterinary Parasitology - April 10, 2017 Category: Veterinary Research Source Type: research
Prevalence and risk factors for wheezing and allergic diseases in preschool children: A perspective from the Mediterranean coast of Turkey.
CONCLUSION: Our study was the first epidemiological study in preschool children in the Mediterranean region of Turkey and demonstrated a high prevalence of asthma and allergic diseases, probably related to humid climatic properties in addition to other environmental and genetic factors.
PMID: 28410872 [PubMed - as supplied by publisher]
Source: Allergologia et Immunopathologia - April 11, 2017 Category: Allergy & Immunology Authors: Bolat E, Arikoglu T, Sungur MA, Batmaz SB, Kuyucu S Tags: Allergol Immunopathol (Madr) Source Type: research
Fueling the Mechanisms of Asthma: Increased Fatty Acid Oxidation in Inflammatory Immune Cells May Represent a Novel Therapeutic Target
Conclusions and clinical relevanceThese novel observations suggest that allergic airway inflammation increases FAO in inflammatory cells to support the production of cytokines, chemokines, and other factors important in the development of asthma. Inhibition of FAO may therefore provide a novel therapeutic approach for the treatment of asthma by re‐purposing existing drugs that block FAO and are approved for the treatment of heart disease.This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Allergy - April 29, 2017 Category: Allergy & Immunology Authors: Amir A. Al ‐Khami, Mohamed A. Ghonim, Luis Del Valle, Salome V. Ibba, Liqin Zheng, Kusma Pyakurel, Samuel C. Okpechi, Jone Garay, Dorota Wyczechowska, Maria D. Sanchez‐Pino, Paulo C. Rodriguez, Hamid A. Boulares, Augusto C. Ochoa Tags: Original Article ‐Basic Mechanisms in Allergic Disease Source Type: research
