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Drug: Insulin

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Improving inpatient glycemic control by diabetes education program in internal medicine residents
ConclusionsLack of confidence and knowledge of insulin treatment in physicians was the important barrier to glycemic management. Consistent education in internal medicine residents led to a significant improvement in inpatient glycemic control.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - July 11, 2019 Category: Endocrinology Source Type: research

IJERPH, Vol. 16, Pages 3356: Effectiveness of Diabetes Community Sharp Disposal Education Module in Primary Care: An Experimental Study in North-East Peninsular Malaysia
Conclusions: The Diabetes Community Sharp Disposal Education Module was an effective health education tool to improve knowledge and encourage Malaysian diabetic patients to engage with proper sharp disposal practices.
Source: International Journal of Environmental Research and Public Health - September 10, 2019 Category: Environmental Health Authors: Ummu Atiyyah Hasan Suhaily Mohd Hairon Najib Majdi Yaacob Aziah Daud Anees Abdul Hamid Norzaihan Hassan Mohd Faiz Ariffin Lau Yi Vun Tags: Article Source Type: research

Metabolic syndrome: The Indian public health perspective
Publication date: Available online 13 January 2020Source: Medical Journal Armed Forces IndiaAuthor(s): Rajvir BhalwarAbstractMetabolic Syndrome (MetS) is a clustering of specific risk factors, namely, central obesity, raised blood pressure, impaired fasting glucose, raised triglycerides, and low levels of high-density lipoprotein-cholesterol (HDL-C). This constellation is triggered by insulin resistance and its resultant hyperinsulinemia. The two most important and universally agreed causes of insulin resistance are increased body fat (particularly central obesity) and physical inactivity. Other causes include certain gene...
Source: Medical Journal Armed Forces India - January 15, 2020 Category: General Medicine Source Type: research

Improved insulin injection technique, treatment satisfaction and glycemic control: results from a large cohort education study
ConclusionThe study showed that proper selection of pen and professional education can result in the improvement of insulin injection technique, higher patients’ satisfaction and better glycemic control.
Source: Journal of Clinical and Translational Endocrinology - February 5, 2020 Category: Endocrinology Source Type: research

Genetics and Pathophysiology of Maturity-onset Diabetes of the Young (MODY): A Review of Current Trends.
Authors: Yahaya TO, Ufuoma SB Abstract Single gene mutations have been implicated in the pathogenesis of a form of diabetes mellitus (DM) known as the maturity-onset diabetes of the young (MODY). However, there are diverse opinions on the suspect genes and pathophysiology, necessitating the need to review and communicate the genes to raise public awareness. We used the Google search engine to retrieve relevant information from reputable sources such as PubMed and Google Scholar. We identified 14 classified MODY genes as well as three new and unclassified genes linked with MODY. These genes are fundamentally embedde...
Source: Oman Medical Journal - June 5, 2020 Category: Middle East Health Tags: Oman Med J Source Type: research

Closed-loop control in insulin pumps for type-1 diabetes mellitus: safety and efficacy.
Authors: Fuchs J, Hovorka R Abstract INTRODUCTION: Type 1 diabetes is a lifelong disease with high management burden. The majority of people with type 1 diabetes fail to achieve glycaemic targets. Algorithm-driven automated insulin delivery (closed-loop) systems aim to address these challenges. This review provides an overview of commercial and emerging closed-loop systems. AREAS COVERED: We review safety and efficacy of commercial and emerging hybrid closed-loop systems. A literature search was conducted and clinical trials using day-and-night closed-loop systems during free-living conditions were used to repo...
Source: Expert Review of Medical Devices - June 24, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Evaluation of ultrasound examination combined with intensive injection technique education on insulin-induced lipohypertrophy (LH) management: a prospective cohort study in China
ConclusionsUltrasound examination combined with intensive injection technique education markedly improved glycemic control in diabetes with LH without increasing the insulin dosage, as well as reducing the occurrence of adverse blood glucose events. It can be a new effective approach for LH management.
Source: International Journal of Diabetes in Developing Countries - February 16, 2021 Category: Endocrinology Source Type: research

Role of Structured Education in Reducing Lypodistrophy and its Metabolic Complications in Insulin-Treated People with Type 2 Diabetes: A Randomized Multicenter Case –Control Study
ConclusionWithin a 6-month observation period, intensive structured education yielded consistently improved metabolic results and led to sharp decreases in the hypo rate and the insulin requirement. These improvements resulted in a parallel drop in overall healthcare costs, representing a tremendous economic advantage for the NHS. These positive results should encourage institutions to resolve the apparently intractable problem of LH by financially incentivizing healthcare teams to provide patients with intensive structured education on proper injection technique.Trial RegistrationTrial registration no. 118/15.04.2018, app...
Source: Diabetes Therapy - March 18, 2021 Category: Endocrinology Source Type: research

From Myo-inositol to D-chiro-inositol molecular pathways
CONCLUSIONS: Inositol is fundamental for signal transduction in the brain, kidneys, reproductive organs and other tissues in response to neurotransmitters, hormones and growth factors. Various genes are involved in inositol metabolism and associated pathways. Altered inositol concentrations are observed in several diseases. Analysis of the genes involved in inositol metabolism may provide important information for the clinical management of these conditions.PMID:33755975 | DOI:10.26355/eurrev_202103_25279
Source: European Review for Medical and Pharmacological Sciences - March 23, 2021 Category: Drugs & Pharmacology Authors: A K Kiani S Paolacci A E Calogero R Cannarella G C Di Renzo S Gerli C Della Morte G M Busetto E De Berardinis F Del Giudice L Stuppia F Facchinetti S Dinicola M Bertelli Source Type: research