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Total 484 results found since Jan 2013.

Does moisturising baby skin prevent eczema or food allergies?
Skin care treatments in babies, such as using moisturisers on the skin during the first year of life, probably do not stop them from developing eczema, and probably increase the chance of skin infection.The authors are uncertain how skin care treatments might affect the chances of developing a food allergy. We need evidence from well-conducted studies to determine effects of skin care on food allergies in babies.What are allergies?An immune response is how the body recognises and defends itself against substances that appear harmful. An allergy is a reaction of the body ' s immune system to a particular food or substance (...
Source: Cochrane News and Events - January 14, 2021 Category: Information Technology Authors: Katie Abbotts Source Type: news

Babies With Pets May Be Less Likely to Develop Food Allergies
About 8% of children in the U.S. have a food allergy, roughly double the percentage who did in 2007. It’s not entirely clear why more kids are being diagnosed with food allergies, both in the U.S. and across the world—but as these potentially life-threatening conditions grow more common, lots of researchers are studying how to treat or prevent them. A study published in PLOS ONE on Mar. 29 offers one potential strategy: get a pet. Among thousands of babies in Japan, exposure to cats or dogs during pregnancy or early infancy was associated with a lower risk of developing food allergies, the researchers found. [t...
Source: TIME: Health - March 29, 2023 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthscienceclimate Research Wellbeing Source Type: news

Pathogenic Mechanism and Diagnostic Testing for Drug Allergies.
Abstract 　Three stages of the pathogenic mechanism of drug allergies can be considered: antigen formation, immune reaction and inflammation/disorder reaction. Drugs are thought to form 4 types of antigens: drug only, polymers, drug-carrier conjugates, and metabolite-carrier complexes. Antigens are recognized by B cell receptors and T cell receptors. Helper T cells (Th) are differentiated into four subsets, namely, Th1, Th2, Th17 and regulatory T cells (Treg). Th1 produces interleukin (IL)-2 and interferon (IFN)-γ, and activates macrophages and cytotoxic T cells (Tc). Macrophages induce type IV allergies, and Tc...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - February 3, 2018 Category: Drugs & Pharmacology Authors: Uno K Tags: Yakugaku Zasshi Source Type: research

Impacts of CD40- and CD86-Silenced Antigen-Specific B Cells on the Control of Allergies.
CONCLUSION: This study showed, for the first time, that siRNA-induced CD86-silenced B cells significantly inhibited allergic responses and symptoms antigen-specifically, and that siRNA-induced CD40-/CD86-silenced antigen-specific B cells are a more useful antigen-specific therapy than CD40- or CD86-silenced B cells alone for the control of allergies. Furthermore, it was shown that CD40-/CD86-silenced B cells have stronger inhibition of IgE production and allergic symptoms than CD40-/CD86-silenced DCs. PMID: 31064207 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - May 7, 2019 Category: ENT & OMF Authors: Suzuki M, Matsumoto T, Toyoda K, Nakamura Y, Murakami S Tags: Am J Rhinol Allergy Source Type: research

Agreement Between Predictive, Allergen-Specific IgE Values Assessed by ImmunoCAP and IMMULITE 2000 3gAllergy ™ Assay Systems for Milk and Wheat Allergies.
CONCLUSIONS: The 2 systems may be interchangeable for diagnosis of milk and wheat allergies in young children. PMID: 33191682 [PubMed]
Source: Allergy, Asthma and Immunology Research - November 18, 2020 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Filaggrin gene mutations may influence the persistence of food allergies in Japanese primary school children.
This article is protected by copyright. All rights reserved. PMID: 29369340 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - January 25, 2018 Category: Dermatology Authors: Kono M, Akiyama M, Inoue Y, Nomura T, Hata A, Okamoto Y, Takeichi T, Muro Y, McLean WHI, Shimizu H, Sugiura K, Suzuki Y, Shimojo N Tags: Br J Dermatol Source Type: research

Embodied Memory, Affective Imagination, and Vigilance: Navigating Food Allergies in Japan.
This article, drawing on the experiences of people with severe food allergies in Japan, illustrates the complexities of safely managing allergies when food-and the importance of sharing the same food-is so important to social life. In particular, I argue that individuals develop and practice skills of vigilance and situational awareness to mitigate physical and social risk which emerge through an affective imagination of what they feel could happen in the future, built on embodied memories of what has been experienced prior (e.g., severe allergic reactions and difficult social experiences with food). The development and en...
Source: Culture, Medicine and Psychiatry - September 24, 2020 Category: Psychiatry Authors: Cook EE Tags: Cult Med Psychiatry Source Type: research

Association between gestational hair dye use and allergies at 3 years old: the Japan environment and Children's study
CONCLUSION: Both home and occupation use of hair dye during pregnancy showed a trend of increased odds of allergic rhinitis and asthma in offspring at 3 years. However, the only association that reached significance was in frequency of use analyses between the highest frequency of home hair dye users and allergic rhinitis.PMID:34171376 | DOI:10.1016/j.envres.2021.111530
Source: Environmental Research - June 25, 2021 Category: Environmental Health Authors: Reiji Kojima Ryoji Shinohara Sayaka Horiuchi Sanae Otawa Hiroshi Yokomichi Yuka Akiyama Tadao Ooka Kunio Miyake Zentaro Yamagata Japan Environment and Children ’s Study Group Source Type: research

Prenatal Negative Life Events and Childhood Allergies: The Japan Environment and Children ’s Study (JECS)
Conclusion: Prenatal negative life events may be a risk factor for allergies in children. There was no modification of the effect of these events by social capital.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - May 19, 2022 Category: Allergy & Immunology Source Type: research

Filaggrin gene mutations may influence the persistence of food allergies in Japanese primary school children
This article is protected by copyright. All rights reserved.
Source: British Journal of Dermatology - January 1, 2018 Category: Dermatology Authors: M. Kono, M. Akiyama, Y. Inoue, T. Nomura, A. Hata, Y. Okamoto, T. Takeichi, Y. Muro, W.H.I. McLean, H. Shimizu, K. Sugiura, Y. Suzuki, N. Shimojo Tags: Research Letter Source Type: research

Childhood allergies and obesity relationship: Identification of novel non-invasive biomarkers
Asthma and obesity are among the most common chronic childhood disorders, both having had a parallel dramatic increase in prevalence worldwide in recent decades. The parallel epidemics of asthma and obesity over the past few decades have spurred research into obesity as a risk factor for asthma. However, little is known regarding the impact of asthma on obesity incidence. In a large-scale prospective study, we assess effects of allergies on BMI at age 7 (n=5,158) in Japan. Parents completed the International Study of Asthma and Allergies in Childhood questionnaires about symptoms of allergic diseases (wheeze, rhinoconjunct...
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Goudarzi, H., Konno, S., Araki, A., Ito, S., Ait Bamai, Y., Miyashita, C., Kishi, R. Tags: Epidemiology Source Type: research

Sublingual immunotherapy for pediatric patients with mite allergies
This study aimed to investigate the effectiveness of SLIT in children with dust mite allergies, as well as its adverse effects, at a pediatric general outpatient clinic. I analyzed the data of 181 patients aged 4 to 12 years who tested positive for mite antigen-specific immunoglobulin E, exhibited nasal and/or eye symptoms, and received Miticure. Symptoms were evaluated using the Japanese rhino-conjunctivitis quality of life (QOL) questionnaire no. 1. Wilcoxon tests were used to compare the pretreatment and post-treatment symptom scores. Adverse events were tallied, and Kaplan–Meier curves and Wilcoxon tests were us...
Source: Medicine - January 28, 2022 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Prenatal occupational disinfectant exposure and childhood allergies: the Japan Environment and Childrens study
Conclusion Disinfectant use by pregnant women may be a risk factor for asthma and eczema in offspring. As disinfectants are an effective tool in the prevention of infectious diseases, replication of this study and further research into the mechanisms are warranted.
Source: Occupational and Environmental Medicine - July 14, 2022 Category: Occupational Health Authors: Kojima, R., Shinohara, R., Kushima, M., Horiuchi, S., Otawa, S., Yokomichi, H., Akiyama, Y., Ooka, T., Miyake, K., Yamagata, Z., Japan Environment and Childrens Study Group Tags: Press releases Workplace Source Type: research

Pets Could Help Prevent Food Allergies in Kids
THURSDAY, March 30, 2023 -- While research has shown that having pets can lower the chances of respiratory allergies in children, a new study finds it might also reduce the risk of food allergies. Japanese investigators found that young children...
Source: Drugs.com - Daily MedNews - March 30, 2023 Category: General Medicine Source Type: news

Dr William Frankland, immunologist behind pollen count, dies aged 108
‘Grandfather of allergy’ survived three years in Japanese POW camp before pioneering medical careerDr William Frankland, a pioneering British immunologist who transformed the world ’s understanding of allergies, has died aged 108.Frankland improved the lives of millions of hay fever sufferers by developing the idea of apollen count. Until his death the oldest survivor of the Japanese prisoner of war camps, he published a scientific paper in September 2017 aged 105.Continue reading...
Source: Guardian Unlimited Science - April 4, 2020 Category: Science Authors: Alexandra Topping Tags: Immunology Biochemistry and molecular biology Medical research Science UK news Hay fever Allergies Source Type: news