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Total 98 results found since Jan 2013.

Inhibition of Cross-Reactive Carbohydrate Determinants in Allergy Diagnostics.
Authors: Grzywnowicz M, Majsiak E, Gaweł J, Miśkiewicz K, Doniec Z, Kurzawa R Abstract Despite being clinically largely irrelevant, antibodies against cross-reactive carbohydrate determinants (CCD) are an important issue in the in vitro diagnostics, as they may produce false positive or falsely elevated results of the immunoglobulin E class (asIgE) in relation to the actually present level of asIgE. The present chapter demonstrates an effective resolution of this diagnostic issue by the use of a CCD inhibitor in in vitro tests. A synthetic CCD inhibitor, Polycheck® CCD inhibitor, was used in the laboratory diagn...
Source: Advances in Experimental Medicine and Biology - September 23, 2018 Category: Research Tags: Adv Exp Med Biol Source Type: research

What motivates patients with atopic diseases to search the internet-a  focus group study on expectations and demands.
DISCUSSION: In order to promote self-management skills, a web-based service should focus on allergy symptoms, treatment options and day-to-day help. PMID: 30105503 [PubMed - as supplied by publisher]
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - August 16, 2018 Category: Dermatology Tags: Hautarzt Source Type: research

Comparison of Specific Immunoglobulin E with the Skin Prick Test in the Diagnosis of House Dust Mites and Cockroach Sensitization in Patients with Asthma and/or Allergic Rhinitis.
CONCLUSION: serum specific IgE testing to common inhalant allergen in patients with respiratory allergy showed only low-to-moderate sensitivity, but high specificity and PPV. This new assay can be used to diagnose allergen sensitization in the population with high prevalence of TDR and cockroach. PMID: 29950531 [PubMed - in process]
Source: Acta medica Indonesiana - June 30, 2018 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Contribution of Patient Interviews as Part of a Comprehensive Approach to the Identification of Drug-Related Problems on Geriatric Wards
ConclusionWe demonstrated that structured patient interviews identified additional DRPs that other sources did not identify. Embedded within a comprehensive approach, the structured patient interviews were needed as data resource for over one-third of all DRPs.
Source: Drugs and Aging - June 19, 2018 Category: Geriatrics Source Type: research

Allergy and atopy from infancy to adulthood: Messages from the German birth cohort MAS,
Allergic diseases in early and late childhood have become a common health problem across the globe as documented by the first cross-sectional phase of the International Study on Asthma and Allergies in Childhood [ISAAC] in the mid-1990s.1,2 In many industrialized and developing countries the prevalence of asthma, allergic rhinitis and eczema has increased since then or remained at a high plateau as shown by another global ISAAC assessment a decade later.3
Source: Annals of Allergy, Asthma and Immunology - May 24, 2018 Category: Allergy & Immunology Authors: Susanne Lau, Paolo Maria Matricardi, Ulrich Wahn, Young Ae Lee, Thomas Keil Tags: Review Articles Source Type: research

Clinical and Laboratory Profile of Zika and Dengue Infected Patients: Lessons Learned From the Co-circulation of Dengue, Zika and Chikungunya in Brazil
In conclusion, our data characterized the occurrence of an ongoing triple epidemic caused by DENV, ZIKV and CHIKV in Campo Grande, MS, Brazil. Importantly, the knowledge about dengue or zika severity in co-infected individuals is still unknown, however we provided here, new contributions related to the clinical presentations and laboratorial parameters during DENV and ZIKV infections, in an endemic scenario. Author Contributions Performed the experiments: ELA, TMALS, RVC, FBS. Contribute reagents material analyses tools: ELA, FBS, RVC. Wrote the paper: ELA. RVC. Participate in patient enrollment and records: ELA, RVC, TMA...
Source: PLOS Currents Outbreaks - February 15, 2018 Category: Epidemiology Authors: Elzinandes Leal de Azeredo Source Type: research

Importance of comorbidities in the treatment of primary care patients with heart failure —Baseline results of the observational RECODE-HF Study
ConclusionFive somatic comorbidity groups as well as patient-reported psychosocial distress were significantly associated with a higher risk of GP-reported treatment difficulties. Further efforts to address comorbidities in clinical guidelines could be built on these results.
Source: Family Practice - January 29, 2018 Category: Primary Care Source Type: research

Gender-related aspects in occupational allergies – Secondary publication and update
AbstractFor years occupational allergies have been among the most frequently recorded occupational diseases, and both the skin as well as the respiratory tract may be affected. An estimated 9 to 15% of adult asthma is (partially) caused by work-related exposure. Gender-specific differences in exposure cause different risks in the workplace which affect the health of employees. This also applies to exposure and working conditions when handling sensitizing working substances. The presented gender-specific analysis of the German documentation of confirmed occupational respiratory allergic diseases and occupational skin diseas...
Source: World Allergy Organization Journal - December 27, 2017 Category: Allergy & Immunology Source Type: research

IgE sensitization to Aspergillus fumigatus among children in allergological centre of Saratov
Conclusions: IgE sensitization to Af increases the risk of rhinosinusitis in children with allergic rhinitis, and often combined with allergen-induced inflammation in epidermal allergy.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Astafieva, N., Gamova, I., Perfilova, I., Udovichenko, E., Skutchaeva, L., Michailova, I. Tags: Allergy and immunology Source Type: research

Food Allergy Detection Device Could Remove Danger Of Dining Out
BOSTON (CBS) – Clare Maloney-Kolenberg is high school junior from Winchester who is looking forward to traveling to Spain on an exchange program with her Spanish class. But that excitement is coupled with a bit of anxiety due to her food allergies. “I’m allergic to tree nuts, peanuts and sesame,” she told WBZ-TV. It’s a list that can make dining out a bit dicey, even in familiar restaurants near home.  But once you add unfamiliar foods and a language barrier, that increases the odds of a reaction. That’s exactly what happened when Clare ordered ice cream on a trip to Germany with her family. “All of a s...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 7, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Local News Syndicated Local Dr. Mallika Marshall Food Allergy Detection Device Source Type: news

Maternal Exposure of BALB/c Mice to Indoor NO2 and Allergic Asthma Syndrome in Offspring at Adulthood with Evaluation of DNA Methylation Associated Th2 Polarization
Conclusions: Maternal exposure to indoor environmental NO2 causes allergic asthma-related consequences in offspring absent any subsequent lung provocation and potentiates the symptoms of allergic asthma in adult offspring following postnatal allergic sensitization and challenge; this response is associated with the Th2-based immune response and DNA methylation of the IL4 gene. https://doi.org/10.1289/EHP685 Received: 19 June 2016 Revised: 07 June 2017 Accepted: 19 June 2017 Published: 13 September 2017 Address correspondence to N. Sang, College of Environment and Resource, Shanxi University, Taiyuan, Shanxi 030006, P...
Source: EHP Research - September 13, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

This Might Make You Rethink Getting a Tattoo
This article originally appeared on Health.com
Source: TIME: Top Science and Health Stories - September 13, 2017 Category: Science Authors: Amanda MacMillan / Health Tags: Uncategorized are tattoos bad are tattoos bad for you can i get sick from a tattoo long term effects of tattoos Research tattoo dangers tattoo diseases Tattoo health risks tattoo ink tattoo safety tattoo warnings toxins Source Type: news

Updated Global Estimates of Respiratory Mortality in Adults ≥ 30 Years of Age Attributable to Long-Term Ozone Exposure
Conclusions: These findings suggest that the potential magnitude of health benefits of air quality policies targeting O3, health co-benefits of climate mitigation policies, and health implications of climate change-driven changes in O3 concentrations, are larger than previously thought. https://doi.org/10.1289/EHP1390 Received: 17 November 2016 Revised: 19 June 2017 Accepted: 20 June 2017 Published: 28 August 2017 Address correspondence to C.S. Malley, Stockholm Environment Institute, Environment Dept., Environment Building, Wentworth Way, University of York, York, YO10 5NG, UK. Telephone: 44 1904 323685. Email: chri...
Source: EHP Research - August 28, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Accurate quantification of 5 German cockroach (GCr) allergens in complex extracts using multiple reaction monitoring mass spectrometry (MRM MS)
Conclusions and Clinical RelevanceOur data demonstrate that the LC‐MRM MS method is valuable for absolute quantification of allergens in GCr extracts and likely has broader applicability to other complex allergen extracts. Definitive quantification provides a new standard for labelling of allergen extracts, which will inform patient care, enable personalized therapy, and enhance the efficacy of immunotherapy for environmental and food allergies.
Source: Clinical and Experimental Allergy - August 25, 2017 Category: Allergy & Immunology Authors: S. T. Mindaye, J. Spiric, N. A. David, R. L. Rabin, J. E. Slater Tags: ORIGINAL ARTICLE Source Type: research