Clinical and Laboratory Profile of Zika and Dengue Infected Patients: Lessons Learned From the Co-circulation of Dengue, Zika and Chikungunya in Brazil

This study accessed the patients information on demographic characteristics, physical signs and symptoms. Study population This is a cross-sectional and observational study carried out in Brazil during DENV and ZIKV epidemic occurred in 2016. Patients were assisted at the Healthy Unit UPA Coronel Antonino in Campo Grande, MS, Brazil from February to March of 2016. During the study 134 suspected arboviral infection cases were included and submitted to investigation. Patients presenting fever, rash during acute phase of infection (up to the 7th day after disease onset) followed by at least two of the following signals and symptoms: headache, myalgia or arthralgia, conjunctivitis, pruritus, retro-orbital pain and prostration were recruited as suspicion of arboviral infection. Moreover, patients with acute onset of generalized macular or papular rash, pruritus and conjuctival hyperemia were considered as zika suspected cases according to the Brazilian Ministry of Healthy Protocol8. Patients with acute fever presenting two or more of the following signs or symptoms: nausea, vomiting, myalgia, arthralgia, headache, retro orbital pain, petechiae, positive tourniquet test, thrombocytopenia and leucopenia were considered as dengue suspected cases according to the Brazilian Ministry of Health9. An infectious disease physician collected data on demographic characteristics, symptoms and physical signs. Detailed clinical examination was registered immediately after admission and blo...
Source: PLOS Currents Outbreaks - Category: Epidemiology Authors: Source Type: research

Related Links:

Authors: Radi G, Campanati A, Diotallevi F, Molinelli E, Offidani A Abstract BACKGROUND: Apremilast is a "small molecule", an oral phosphodiesterase 4 inhibitor indicated for the twice- daily treatment of adults with psoriasis (PsO) and psoriatic arthritis (PsA). Data concerning clinical experience in real world setting with Apremilast for psoriasis are still exiguous, and aim of this report is to provide our experience in the use of Apremilast in out-patient setting. METHODS: Ten caucasian individuals (6 male, 4 females; mean age 69,3; range 53-81 years) affected by moderate to severe plaque psoriasi...
Source: Giornale Italiano di Dermatologia e Venereologia - Category: Dermatology Tags: G Ital Dermatol Venereol Source Type: research
CONCLUSION: Adding lidocaine to HA gels does modify their rheological properties yet this, to a variable extent depending on the product. J Drugs Dermatol. 2018;17(9):948-954. PMID: 30235380 [PubMed - in process]
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
CONCLUSION: The narrow-spectrum antibiotic sarecycline was safe, well tolerated, and effective for moderate to severe acne, with low rates of side effects common with tetracycline antibiotics. J Drugs Dermatol. 2018;17(9):987-996. PMID: 30235387 [PubMed - in process]
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
CONCLUSIONTo the best of our knowledge, this is the first case report of bile leak from duct of Luschka after mini-gastric bypass treated successfully with relaparoscopy and drainage. Herein we will discuss all the available options of treatment and the challenge of it.
Source: Annals of Medicine and Surgery - Category: General Medicine Source Type: research
Authors: Patel R, Witton R, Potterton R, Smith W, Kaimi I Abstract This paper aims to provide a snapshot analysis of the oral health status of vulnerable adults in Plymouth; and to demonstrate the extent to which oral disease impacts on their normal functioning through the implementation of the Oral Health Impact Profile (OHIP). It is acknowledged that gaining a representative sample of a transient population such as people who are homeless, or individuals affected by problematic use of drugs and/or alcohol is difficult. An opportunity was identified to collect data within the Community Engagement Team's (CET) prog...
Source: Community Dental Health - Category: Dentistry Tags: Community Dent Health Source Type: research
Increased intraocular pressure is linked to diabetes, hypertension and obesity, according to a study published in theAmerican Journal of Ophthalmology.Healio
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
Yi Tong, Qian Jiao, Yuanru Liu, Jiankun Lv, Rui Wang, Lili Zhu
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
ConclusionsThis study has elucidated the genome-wide effects of several adaptogenic herbal extracts in brain cells culture. These data highlight the consistent activation of ASRSPs by adaptogens in T98G neuroglia cells. The extracts affected many genes playing key roles in modulation of adaptive homeostasis, indicating their ability to modify gene expression to prevent stress-induced and aging-related disorders. Overall, this study provides a comprehensive look at the molecular mechanisms by which adaptogens exerts stress-protective effects.Graphycal abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
Everyone always jokes with doctors, “What happens if you get sick?” Some of us laugh off the question. The busy schedule of health care often means our own health comes last. However, what happens when it’s a chronic disease that requires treatment? Then the answer to this question is a little different. I am a family medicine physician dealing with congenital heart disease (CHD). Saying that someone has congenital heart disease is a broad statement. CHD affects 40,000 babies born each year, but the severity and complications have a broad range. Some infants may only have a small hole between the two vent...
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions Cardiology Source Type: blogs
Inhibition of α-Glucosidase, Intestinal Glucose Absorption, and Antidiabetic Properties by Caralluma europaea. Evid Based Complement Alternat Med. 2018;2018:9589472 Authors: Ouassou H, Zahidi T, Bouknana S, Bouhrim M, Mekhfi H, Ziyyat A, Legssyer A, Aziz M, Bnouham M Abstract Many medicinal plants around the world are used for therapeutic purposes against several diseases, including diabetes mellitus. Due to their composition of natural substances that are effective and do not represent side effects for users, unlike synthetic drugs, in this study, we investigated the inhibitory effect of Carallu...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
More News: Allergy | Allergy & Immunology | Anorexia | Arthritis | Asthma | Babies | Babies Heart Conditions | Back Pain | Bleeding | Brain | Brazil Health | Cardiology | Chikungunya | Children | Conjunctivitis | Cough | Dengue Fever | Diabetes | Diabetes Mellitus | Eating Disorders & Weight Management | Endemics | Endocrinology | Environmental Health | Epidemics | Epidemiology | Epistaxis (Nosebleeds) | France Health | Gastroenterology | Germany Health | Guillain-Barr Syndrome | Headache | Heart | Hepatomegaly | Hypertension | Infectious Diseases | Intensive Care | International Medicine & Public Health | Laboratory Medicine | Lessons | Liver | Low Back Pain | Medical Ethics | Migraine | Neurology | Nicaragua Health | Outbreaks | Pain | Pain Management | Parasitic Diseases | Parasitology | Plagiocephaly | Pregnancy | Respiratory Medicine | Rheumatoid Arthritis | Rheumatology | Sinusitis | Statistics | Study | Thailand Health | Thrombocytopenia | Urology & Nephrology | Virology | Warnings | Women | Zika Virus