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Total 388 results found since Jan 2013.

Immunoproteomic identification of allergenic proteins in pecan (Carya illinoinensis) pollen
This study has identified 17 IgE binding proteins from pecan pollen including proteins widely recognized as allergens and panallergens. These findings will contribute to develop specific diagnosis and treatment of pecan pollen allergy. SIGNIFICANCE: Pecan is a tree highly valued for its fruits that have a great commercial value. To date three pecan seed storage proteins have been officially recognized by the WHO/IUIS allergen nomenclature subcommittee as food allergens (Car i 1, Car i 2 and Car i 4). Pecan tree pollen is highly allergenic and a clinically relevant cause of allergies in North America (USA and Mexico) and re...
Source: Journal of Proteomics - August 15, 2021 Category: Biochemistry Authors: Martha Beatriz Morales-Amparano Alejandra Valenzuela-Corral Gabriela Ramos-Clamont Montfort Luz V ázquez-Moreno Abraham Escobedo-Moratilla Guillermo Pastor-Palacios Cesar é Ovando-Vázquez Luis M Teran Jos é Ángel Huerta-Ocampo Source Type: research

Association of serum CD14 level and functional polymorphism C-159T in the promoter region of CD14 gene with allergic rhinitis
This study aimed to determine the associat ion between C-159T polymorphism in the CD14 gene promoter region and serum CD14 levels and the risk of Allergic rhinitis Egyptian patients and to test the validity of serum CD14 level measurement in predicting AR. This case–control study included 45 patients with AR referred to Allergy and Immunol ogy Unit, Zagazig University Hospital, Zagazig, Egypt, and 45 healthy subjects as controls. Serum CD14 levels were measured by ELISA. The polymerase chain reaction-restriction fragment length polymorphism technique was used to detect C-159T gene polymorphism in the CD14 promoter region...
Source: Clinical and Experimental Medicine - June 7, 2023 Category: Research Source Type: research

Correction of the deviated septum: from ancient Egypt to the endoscopic era
ConclusionThis paper discusses the evolution of septoplasty techniques over time from the initial undertakings of the ancient Egyptians to the modern‐day septoplasty. While the principles behind septoplasty have remained much the same, experience has allowed for refinement of surgical technique. No doubt new instrumentations and innovations will further help to tailor the practice of septoplasty to the anatomy and functional needs of each individual patient.
Source: International Forum of Allergy and Rhinology - August 18, 2014 Category: Allergy & Immunology Authors: Nicole L. Aaronson, Eugenia M. Vining Tags: REVIEW ARTICLE Source Type: research

Intraoperative magnesium sulphate decreases agitation and pain in patients undergoing functional endoscopic surgery: A randomised double-blind study
BACKGROUND: Postoperative agitation is harmful for the patient as it may be associated with removal of catheters, nasal packs, oxygen masks and self-injury, and pose a danger to operating theatre staff. OBJECTIVE: The current study investigated the potential role of magnesium sulphate in treatment of postoperative agitation following functional endoscopic sinus surgery. DESIGN: A randomised, double-blinded, placebo-controlled trial. SETTING: ENT operating room, Menofia University Hospitals, Egypt. PATIENTS: A total of 312 adult patients (171 men and 141 women) were enrolled in the study. Eighteen patients (10 men and e...
Source: European Journal of Anaesthesiology - September 6, 2017 Category: Anesthesiology Tags: Pain Source Type: research

The clinical burden of allergic rhinitis in five Middle Eastern countries: results of the SNAPSHOT program
The SNAPSHOT program provides current data on the allergic rhinitis burden in the adult general population of five Middle Eastern countries (Egypt, Turkey, Kuwait, Saudi Arabia and the United Arab Emirates, th...
Source: Allergy, Asthma and Clinical Immunology - November 19, 2018 Category: Allergy & Immunology Authors: Ahmed Al-Digheari, Bassam Mahboub, Hesham Tarraf, Taskin Yucel, Isabella Annesi-Maesano, Adam Doble, Aaicha Lahlou, Luqman Tariq, Fayaz Aziz and Abdelkader El Hasnaoui Tags: Research Source Type: research

ST18 Enhances PV-IgG-Induced Loss of Keratinocyte Cohesion in Parallel to Increased ERK Activation
Discussions Autoantibodies targeting Dsg1 and Dsg3 are pathogenic and cause blister formation by inducing structural desmosomal changes in the skin of PV patients (42). However, the mechanisms underlying disease development and the factors enhancing its manifestation have not yet been fully elucidated. Secondary factors promoting severity of the disease include non-Dsg antibodies (43) as well as genetic alterations such as recently reported ST18 SNPs (29–31) and may also entail keratinocyte-derived cytokine release. Here, we investigate the effect of ST18 overexpression and cytokine secretion on PV-IgG mediated l...
Source: Frontiers in Immunology - April 16, 2019 Category: Allergy & Immunology Source Type: research

Autoimmune Disease in Women: Endocrine Transition and Risk Across the Lifespan
Conclusion Autoimmune disease states show strong associations with endocrinological changes in human and animal studies. There is clear evidence for the role of sex steroids in the immune disturbances that result in autoimmune diseases (Figure 2). The majority of women who pass through the different endocrinological transition states do not succumb to autoimmune diseases. FIGURE 2 Figure 2. Factors that contribute to increased incidence and prevalence of autoimmunity in women. In women (46XX) with genetic susceptibility to autoimmune states, external environmental stimuli affect modifying factors as well as endo...
Source: Frontiers in Endocrinology - April 28, 2019 Category: Endocrinology Source Type: research

Comparative Evaluation of Colon Cancer Specific Antigen-2 Test and Chromocolonoscopy for Early Detection of Egyptian Patients with Colorectal Cancer
Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry - September 7, 2020 Category: Allergy & Immunology Authors: Elhossary, Marwa Hawash, Nehah Badawi, Rehab Yousef, Mohamed Abd-Elsalam, Sherief Elhendawy, Mohammed Wasfy, Rania Abou-Saif, Sabry ElBendary, Amal Ismail, Saber Tags: Research article Source Type: research

M002 a case of carbamazepine induced toxic epidermal necrolysis in a middle aged egyptian female
Toxic Epidermal Necrolysis (TEN) is a rare, drug induced life-threatening mucocutaneous condition caused by immune system activation. TEN is associated with widespread keratinocyte death causing full-thickness denudation of the skin and mucosa, resulting in sepsis and a mortality rate of 30%.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2020 Category: Allergy & Immunology Authors: A. Elmazaly, M. Elshayeb, N. Melek, O. Zeyada, S. Roman, M. Mohamed, S. Fouad, R. El Adwey, N. Mattias, R. Abdelfatah, O. Sobh Source Type: research

The Correlation Between the Autotaxin Enzyme and Pruritus in Egyptian Patients Suffering from Chronic Liver Disease
Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry - November 26, 2021 Category: Allergy & Immunology Authors: Asal, Fathia Ziada, Dina Wageh, Ayman El-Kohy, Mohammed Hawash, Nehad Abd-Elsalam, Sherief Badawi, Rehab Tags: Research article Source Type: research

Food and Aeroallergen Sensitization in IgE -Mediated Asthma in Egypt
CONCLUSION: Fungi and cow's milk are the chief sensitizing allergens in Egyptian patients with atopic asthma. This study represents the first report of sensitization in atopic adult asthma using a large extract panel in Upper Egypt.PMID:35265222 | PMC:PMC8822223 | DOI:10.2174/1874306402115010052
Source: Open Respiratory Medicine Journal - March 10, 2022 Category: Respiratory Medicine Authors: Abdellah H K Ali Source Type: research