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Condition: Disability
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Total 676 results found since Jan 2013.

Korean Stroke Cohort for functioning and rehabilitation (KOSCO): study rationale and protocol of a multi-centre prospective cohort study
This study is designed as a 10-year, longitudinal follow-up investigating the residual disabilities, activity limitations, and quality of life issues arising in patients suffering from first-ever stroke. The main objectives of this study are to identify the factors that influence residual disability and long-term quality of life. The secondary objectives of this study are to determine the risk of mortality and recurrent vascular events in patients with acute first-ever stroke. We will investigate longitudinal health behaviors and patterns of healthcare utilization, including stroke rehabilitation care. We will also investi...
Source: BMC Neurology - March 25, 2015 Category: Neurology Authors: Won ChangMin SohnJongmin LeeDeog KimSam-Gyu LeeYong-Il ShinGyung-Jae OhYang-Soo LeeMin JooEun HanYun-Hee Kim Source Type: research

Head Position in Stroke Trial (HeadPoST) – sitting-up vs lying-flat positioning of patients with acute stroke: study protocol for a cluster randomised controlled trial
DiscussionHeadPoST is a large international clinical trial in which we will rigorously evaluate the effects of different head positioning in patients with acute stroke.Trial registrationClinicalTrials.gov identifier: NCT02162017 (date of registration: 27 April 2014); ANZCTR identifier: ACTRN12614000483651 (date of registration: 9 May 2014). Protocol version and date: version 2.2, 19 June 2014.
Source: Trials - June 5, 2015 Category: Journals (General) Authors: Paula Muñoz-VenturelliHisatomi ArimaPablo LavadosAlejandro BrunserBin PengLiying CuiLily SongLaurent BillotElizabeth BoadenMaree HackettStephane HeritierStephen JanSandy MiddletonVerónica OlavarríaJoyce LimRichard LindleyEmma HeeleyThompson RobinsonOct Source Type: research

The scope for improvement in hyper-acute stroke care in Scotland
Publication date: Available online 11 September 2015 Source:Operations Research for Health Care Author(s): Evin Uzun Jacobson, Steffen Bayer, James Barlow, Martin Dennis, Mary Joan MacLeod Thrombolysis is associated with reduced disability for selected patients who have suffered ischemic stroke. However only a fraction of all patients who have suffered this type of stroke receive thrombolysis. The short time window of 4.5 h in which treatment is licensed means that rapid care and well-organised pathways are essential. We studied measures to increase the uptake of thrombolysis through a better understanding of the ho...
Source: Operations Research for Health Care - September 11, 2015 Category: Hospital Management Source Type: research

Potential analyses for research on occupational therapy-led training of activities of daily living in stroke patients.
Authors: Müller C, Glässel A, Marotzki U, Voigt-Radloff S Abstract HEALTH PROBLEM: Every year about 200,000 people in Germany suffer from a first stroke and 65,000 persons from a recurrent stroke. Stroke is one of the major causes of acquired life-long disability. It is associated with multiple limitations in functioning, activities of daily living and social participation. People with stroke must develop and apply considerable coping and adaptation strategies to manage the consequences of disabilities in daily life. Insufficient adaptations may result in social isolation, depressive disorders, need for medical a...
Source: Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen - December 2, 2015 Category: Health Management Tags: Z Evid Fortbild Qual Gesundhwes Source Type: research

Stroke: Temporal Trends and Association with Atmospheric Variables and Air Pollutants in Northern Spain.
This study could be a first step for implementing stroke alert protocols depending on air pollution levels and circulation patterns forecasts. PMID: 27990617 [PubMed - as supplied by publisher]
Source: Cardiovascular Toxicology - December 18, 2016 Category: Cardiology Authors: Santurtún A, Ruiz PB, López-Delgado L, Sanchez-Lorenzo A, Riancho J, Zarrabeitia MT Tags: Cardiovasc Toxicol Source Type: research

Role of Brain Biomarker in Predicting Clinical Outcome in Hypertensive Cerebrovascular Ischemic Stroke
This study was undertaken to evaluate the role of serum neuron specific enolase (NSE) in prediction of disability and neurological worsening in hypertensive ischemic cerebrovascular stroke. 80 hypertensive ischemic stroke patients diagnosed by a neurologist as per WHO definition along with radiological findings suggestive of cerebrovascular stroke and differentiating from hemorrhagic stroke and 60 controls having essential hypertension coming to hospital because of regular checkup or headache but with no neurological disease were included in the study. Neurological disability was assessed by NIHSS at the time of admission ...
Source: Indian Journal of Clinical Biochemistry - April 1, 2018 Category: Biochemistry Source Type: research

Brain Functional Reserve in the Context of Neuroplasticity after Stroke.
Abstract Stroke is the second cause of death and more importantly first cause of disability in people over 40 years of age. Current therapeutic management of ischemic stroke does not provide fully satisfactory outcomes. Stroke management has significantly changed since the time when there were opened modern stroke units with early motor and speech rehabilitation in hospitals. In recent decades, researchers searched for biomarkers of ischemic stroke and neuroplasticity in order to determine effective diagnostics, prognostic assessment, and therapy. Complex background of events following ischemic episode hinders suc...
Source: Neural Plasticity - April 4, 2019 Category: Neurology Authors: Dąbrowski J, Czajka A, Zielińska-Turek J, Jaroszyński J, Furtak-Niczyporuk M, Mela A, Poniatowski ŁA, Drop B, Dorobek M, Barcikowska-Kotowicz M, Ziemba A Tags: Neural Plast Source Type: research

Advances in stroke medicine.
Authors: Campbell BC Abstract In recent years, reperfusion therapies such as intravenous thrombolysis and endovascular thrombectomy for ischaemic stroke have dramatically reduced disability and revolutionised stroke management. Thrombolysis with alteplase is effective when administered to patients with potentially disabling stroke, who are not at high risk of bleeding, within 4.5 hours of the time the patient was last known to be well. Emerging evidence suggests that other thrombolytics such as tenecteplase may be even more effective. Treatment may be possible beyond 4.5 hours in patients selected using brain imagi...
Source: Medical Journal of Australia - May 6, 2019 Category: General Medicine Tags: Med J Aust Source Type: research

Risk factors and subtypes of ischemic stroke in young patients: an observational study from a teaching hospital in Saudi Arabia.
Authors: Shahid R Abstract Young adults are a key part of any society and the psychosocial and economic burden of any chronic or devastating disease in this particular group has significant consequences and impacts negatively on the development of the society as a whole. Although stroke in this age group is relatively rare, its consequences, in terms of lifelong dependence and disability, are substantial. Therefore, it is important to address this issue. In this retrospective epidemiological study, we analyzed the medical records of young patients (aged 18- 45 years) with a diagnosis of stroke during the study peri...
Source: Functional Neurology - September 28, 2019 Category: Neurology Tags: Funct Neurol Source Type: research

Organizing Healthcare for Optimal Acute Ischemic Stroke Treatment.
Authors: Vidale S, Agostoni EC Abstract Stroke is a major health-care problem that represents a leading cause of death and also the top cause of disability in adulthood. In recent years there has been a significant paradigm shift in treatments for acute ischemic stroke to favor earlier reperfusion therapy, mainly using the systemic infusion of recombinant tissue plasminogen activator. Subsequent trials found that combining this treatment with endovascular therapy was effective in selected patients. The increased complexity of acute stroke treatments has resulted in a substantial reorganization of stroke care. This ...
Source: Journal of Clinical Neurology - April 23, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Role of Renal Dysfunction as a Prognostic Factor in Acute Stroke Patients at a Tertiary Hospital in Northeastern Nigeria
Saudi J Kidney Dis Transpl. 2021 Jan-Feb;32(1):199-203. doi: 10.4103/1319-2442.318524.ABSTRACTChronic kidney disease (CKD) and stroke share many common risk factors, and the presence of CKD confers added risk factors for stroke. With increasing interest and understanding of the close relationship between the kidney and the brain, this study aims to assess the prevalence and impact of renal dysfunction on outcomes acute stroke patients. This is a prospective hospital-based study carried out in the neurology unit of University of Maiduguri Teaching Hospital, Maiduguri, northeastern Nigeria. The study population consisted of ...
Source: Saudi Journal of Kidney Diseases and Transplantation - June 19, 2021 Category: Urology & Nephrology Authors: Mohammad Maina Sulaiman Musa Mamman Watila Jummai Shettima Ibrahim Ummate Yakubu Wilberforce Nyandaiti Source Type: research