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Condition: Myocarditis
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Total 268 results found since Jan 2013.
Postapproval Outcomes: The Berlin Heart EXCOR Pediatric in North America
The Berlin Heart EXCOR Pediatric Ventricular Assist Device (BH) was approved for use in the United States in December 2011, based on a prospective investigational device exemption (IDE) trial. Strict exclusion criteria for the trial selected a low-risk “ideal” cohort. We sought to determine whether postapproval usage of the BH in a “real world” cohort of recipients would result in similar outcomes. Preimplant diagnostic information was collected for all patients. Efficacy was evaluated by comparison of all children (efficacy group, n = 247) implanted between FDA approval and April 2015 to those in the IDE trial (ID...
Source: ASAIO Journal - February 25, 2017 Category: Medical Equipment Tags: Pediatric Circulatory Support Source Type: research
Left ventricular wall motion abnormalities: What can they tell us about stroke recurrence?
Left ventricular wall motion abnormalities (LVWMAs) are commonly observed in a variety of medical conditions, including coronary artery disease, congestive heart failure, stress-induced cardiomyopathy, myocarditis, chronic renal disease, and stroke.1–4 Their underlying disease mechanisms and their potential causative role for stroke remain inadequately elucidated. LVWMAs may directly increase stroke risk through thrombus formation in the left ventricle5 or may merely indicate the burden of systemic atherosclerosis underlying stroke, and not the primum movens.
Source: Neurology - February 5, 2017 Category: Neurology Authors: Brouns, R. Tags: Cardiac, Embolism, Infarction EDITORIALS Source Type: research
Galectins - a potential target for cardiovascular therapy.
Abstract
Cells constantly adapt to external humoral cues like cytokines and hormones, but practically most cellular behavior is under locally guided control via cell-cell interactions. Galectins (Gals) are one of the most prominent members of the group of molecules involved in this intercellular signaling. They are the family of β-galactoside specific lectins and consist of 15 different types, each with a specific function. They play crucial role in the immune system, inflammation, wound healing and carcinogenesis. In recent times, the role of Gals in the development of cardiovascular disease (CVD) has gained att...
Source: Current Vascular Pharmacology - January 31, 2017 Category: Drugs & Pharmacology Authors: Ashraf GM, Perveen A, Zaidi SK, Ahmad A, Shakil S, Firoz CK, Jabir NR, Hassan I, Khan TA, Yarla NS, Tabrez S Tags: Curr Vasc Pharmacol Source Type: research
Myocardial fibrosis detected with Gadolinium Delayed Enhancement in Cardiac Magnetic Resonance Imaging and Ventriculoarterial Coupling alterations in patients with Acute Myocarditis.
CONCLUSION: In acute myocarditis patients, DGE is related to neither EF nor VAC; however, EF significantly affects the VAC status. Further studies are needed to investigate the potential quantitative, rather than qualitative, relationships between these variables.
PMID: 28081949 [PubMed - as supplied by publisher]
Source: Hellenic Journal of Cardiology - January 15, 2017 Category: Cardiology Tags: Hellenic J Cardiol Source Type: research
Application of Cardiac Troponin in Cardiovascular Diseases Other Than Acute Coronary Syndrome Reviews
BACKGROUND:
Increased cardiac troponin concentrations in acute coronary syndrome (ACS) identify patients with ongoing cardiomyocyte necrosis who are at increased risk. However, with the use of more precise assays, cardiac troponin increases are commonly noted in other cardiovascular conditions as well. This has generated interest in the use of cardiac troponin for prognostic assessment and clinical management of these patients. In this review, we have summarized the data from studies investigating the implications of cardiac troponin concentrations in various acute and chronic conditions beyond ACS, i.e., heart failure, my...
Source: Clinical Chemistry - December 29, 2016 Category: Chemistry Authors: Eggers, K. M., Lindahl, B. Tags: Proteomics and Protein Markers Reviews Source Type: research
Experiences With Aggressive Cardiac Rehabilitation in Pediatric Patients Receiving Mechanical Circulatory Supports.
Authors: Amao R, Imamura T, Sawada Y, Endo S, Ozaki S, Okamura K, Masuzawa A, Takaoka T, Hirata Y, Shindo T, Ono M, Haga N
Abstract
Although some patients with fulminant myocarditis can be rescued owing to the improvements in mechanical circulatory support therapy, there are few reports providing evidence of cardiac rehabilitation during mechanical circulatory supports, particularly among pediatric patients. We treated two pediatric patients who underwent aggressive cardiac rehabilitation during mechanical support. Five days after the initiation of extracorporeal membrane oxygenation therapy aggressive cardiac reha...
Source: International Heart Journal - November 12, 2016 Category: Cardiology Tags: Int Heart J Source Type: research
Takotsubo-Like Myocardial Dysfunction in Ischemic Stroke Clinical Sciences
This study included 23 patients (0.42%). The mean age was 70.7±13.9 years, with predominance of women (73.9%) and typical pattern of Takotsubo-like myocardial dysfunction (91.3%). They were associated with short-term poor functional outcomes, including high mortality, neurological deterioration, and functional status at discharge, compared with those without (39.1% versus 2.4%, 47.8% versus 7.4%; and median [interquartile range], 5 [5–6] versus 3 [2–4]; all P
Source: Stroke - October 23, 2016 Category: Neurology Authors: Jung, J.-M., Kim, J.-G., Kim, J. B., Cho, K.-H., Yu, S., Oh, K., Kim, Y.-H., Choi, J.-Y., Seo, W.-K. Tags: Risk Factors, Cardiomyopathy, Prognosis, Mortality/Survival, Ischemic Stroke Original Contributions Source Type: research
Alcoholic cardiomyopathy : The result of dosage and individual predisposition.
Authors: Maisch B
Abstract
The individual amount of alcohol consumed acutely or chronically decides on harm or benefit to a person's health. Available data suggest that one to two drinks in men and one drink in women will benefit the cardiovascular system over time, one drink being 17.6 ml 100 % alcohol. Moderate drinking can reduce the incidence and mortality of coronary artery disease, heart failure, diabetes, ischemic and hemorrhagic stroke. More than this amount can lead to alcoholic cardiomyopathy, which is defined as alcohol toxicity to the heart muscle itself by ethanol and its metabolites. Historical exa...
Source: Herz - September 3, 2016 Category: Cardiology Tags: Herz Source Type: research
In the heart of MELAS syndrome
With interest we read the article by Youssef et al. about a 25year old male with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome who experienced an acute deterioration of left ventricular function being attributed to myocarditis from a presumed parvovirus B19 infection [1]. We have the following comments and concerns.
Source: International Journal of Cardiology - April 6, 2016 Category: Cardiology Authors: Josef Finsterer, Sinda Zarrouk-Mahjoub Tags: Correspondence Source Type: research
The emerging role of galectins in cardiovascular disease.
Abstract
Galectins are an ancient family of β-galactoside-specific lectins and consist of 15 different types, each with a specific function. They play a role in the immune system, inflammation, wound healing and carcinogenesis. In particular the role of galectin in cancer is widely studied. Lately, the role of galectins in the development of cardiovascular disease has gained attention. Worldwide cardiovascular disease is still the leading cause of death. In ischemic heart disease, atherosclerosis limits adequate blood flow. Angiogenesis and arteriogenesis are highly important mechanisms relieving ischemia by rest...
Source: Vascular Pharmacology - March 2, 2016 Category: Drugs & Pharmacology Authors: van der Hoeven NW, Hollander MR, Yıldırım C, Jansen MF, Teunissen PF, Horrevoets AJ, van der Pouw Kraan TC, van Royen N Tags: Vascul Pharmacol Source Type: research
Cardiac eosinophilic granulomatosis with polyangiitis: rapid imaging with contrast CT and contrast echo aids early diagnosis
A 49-year-old male asthmatic (on Montelukast) with multiple sclerosis presented with shortness of breath and generalised weakness. On examination, he was in cardiac failure with a systolic murmur, rapid atrial fibrillation and weakness in all four limbs with slurred speech. His white cell count was 37x109/L, eosinophils 25x109/L, urea 13.6 mmol/L, creatinine 131 μmol/L, troponin I 4448 ng/L, anti-neutrophil cytoplasmic antibodies (ANCA) weakly positive (negative myeloperoxidase (MPO) and proteinase 3 (PR3)). Differential diagnoses included stroke, myocarditis and eosinophilic granulomatosis with polyangii...
Source: Heart Asia - February 4, 2016 Category: Cardiology Authors: Abraham, D., Freeman, L. J. Tags: Images in cardiovascular medicine Source Type: research
Arterial ischemic stroke in children with cardiac disease
Conclusions:
Infants with cyanotic CHD were most frequently affected by AIS during the periprocedural period. Prospective cohort studies are required to determine effective primary and secondary prevention strategies.
Source: Neurology - December 7, 2015 Category: Neurology Authors: Asakai, H., Cardamone, M., Hutchinson, D., Stojanovski, B., Galati, J. C., Cheung, M. M. H., Mackay, M. T. Tags: Childhood stroke, All Cerebrovascular disease/Stroke, All Pediatric, Cardiac, Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke ARTICLE Source Type: research
Eligibility and Disqualification Recommendations for Competitive Athletes With Cardiovascular Abnormalities: Task Force 3: Hypertrophic Cardiomyopathy, Arrhythmogenic Right Ventricular Cardiomyopathy and Other Cardiomyopathies, and Myocarditis: A Scientific Statement From the American Heart Association and American College of Cardiology.
g, Council on Cardiovascular and Stroke Nursing, Council on Functional Genomics and Translational Biology, and the American College of Cardiology
PMID: 26621644 [PubMed - in process]
Source: Circulation - December 1, 2015 Category: Cardiology Authors: Maron BJ, Udelson JE, Bonow RO, Nishimura RA, Ackerman MJ, Estes NA, Cooper LT, Link MS, Maron MS, American Heart Association Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology, Council on Cardiovascular Disease in the You Tags: Circulation Source Type: research
Atypical Presentation of Intracardiac Floating Thrombi in Hypereosinophilic Syndrome Complicated With Stroke and Systemic Embolization: A Case Report
We present a case with atypical cardiac presentation with massive intracardiac fragile thrombi, causing peripheral emboli and strokes.
HES can present as floating thrombi with thin attachment to the left ventricle, and clinicians should also be vigilant of thromboembolic complications and initiate early therapy to prevent or reduce the potential complications of HES.
Source: Medicine - October 1, 2015 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
A Technique for Implantation of the CentriMag Left Ventricular Assist Device to Allow Ambulation and Rehabilitation in Patients with Heart Failure.
CONCLUSIONS: CentriMag LVAD implantation via a right thoracotomy is a feasible approach that provides adequate hemodynamic support while allowing patients to ambulate, making subsequent cardiac transplantation less complicated by allowing the avoidance of a repeat sternotomy.
PMID: 26115147 [PubMed - as supplied by publisher]
Source: The Heart Surgery Forum - June 27, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Tribble C, Urencio M, Aru G, Merrill W Tags: Heart Surg Forum Source Type: research
