Erratum
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Erratum Source Type: research

Successful Lung Transplantation After 213 Days of Extracorporeal Life Support: Role of Oxygenator-Right Ventricular Assist Device
Venovenous extracorporeal membrane oxygenation (VV ECMO) can successfully support patients with refractory respiratory failure and is widely accepted as a bridge to recovery or bridge to transplantation. However, some problems hinder success. Recirculation, an innate complication of VV ECMO, hamper efficient oxygenation. Right ventricular (RV) failure secondary to respiratory failure is not uncommon and can be reversed by VV ECMO. But there are often times when RV failure gets worse, and since VV ECMO is no longer effective, additional measures are needed. Moreover, peripheral cannulation restricts active rehabilitation le...
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Case Report Source Type: research

Biventricular Support Using ProtekDuo Cannula in a Child
We report a successful pediatric bridge to transplant following application of the ProTekDuo Cannula to provide right ventricular support in a 12-year-old child with biventricular cardiomyopathy and on left ventricular assist device support. We are unaware of any other reports of pediatric use of this device in the medical literature. (Source: ASAIO Journal)
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Case Report Source Type: research

Veno-Venous Extracorporeal Membrane Oxygenation to Treat Acute Respiratory Distress Syndrome in an Adult with Fontan Palliation
In patients with Fontan palliation, the systemic and pulmonary circulation is in series and supported by a single ventricle, resulting in fragile hemodynamics. Cardiac output is driven by low pressure nonpulsatile pulmonary flow and is highly dependent on pulmonary vascular resistance. An acute respiratory distress syndrome (ARDS) can rapidly alter this physiology and lead to severe cardiogenic shock. Herein, we describe the case of a 40 year old man with a classic modified Fontan procedure and bidirectional Glenn shunt who developed ARDS with cardiogenic shock following a resuscitated cardiac arrest with presumed aspirati...
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Case Report Source Type: research

Understanding the Impact of Hypertension on Left Ventricular Assist Device Pump Function and Thrombotic Risk
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Brief Communication Source Type: research

Development of New Hemodialysis Catheter Using Numerical Analysis and Experiments
In this study, we numerically analyzed the design of the HD catheter’s side hole and distal tip for evaluating their effects on hemodynamic factors such as recirculation rate (RR), shear stress, and blood damage index (BDI). The results indicated that a larger side hole and a nozzle-shaped distal tip can significantly reduce the RR and shear stress around the HD catheter. Furthermore, based on these hemodynamic insights, we proposed three new HD catheter designs and compared their performances with existing catheters using numerical and in vitro methods. These new designs exhibited lower RRs and BDI values, thus prov...
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Renal/Extracorporeal Blood Treatment Source Type: research

Mechanisms of Peritoneal Acid-Base Kinetics During Peritoneal Dialysis: A Mathematical Model Study
To investigate mechanisms of acid-base changes during peritoneal dialysis (PD), a mathematical model was developed that describes kinetics of peritoneal bicarbonate, CO2, and pH during the dwell with both high and low lactate-containing dialysis fluids. The model was based on a previous modification of the Rippe 3-Pore model of water and solute kinetic transport across the peritoneal membrane during the PD dwell. A central feature of the present modification is an electroneutrality constraint on peritoneal-fluid ion concentrations, which results in the conclusion that peritoneal bicarbonate-concentration kinetics are entir...
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Renal/Extracorporeal Blood Treatment Source Type: research

Tethered Liquid Perfluorocarbon Coating for 72 Hour Heparin-Free Extracorporeal Life Support
We examined application of TLP to complete ECLS circuits (membranes, tubing, pumps, and catheters) during 72 hours of ECLS in healthy swine (n = 5/group). We compared TLP-coated circuits used without systemic anticoagulation to standard of care: heparin-coated circuits with continuous heparin infusion. Coagulopathic complications, device performance, and systemic effects were assessed. We hypothesized that TLP reduces circuit thrombosis and iatrogenic bleeding, without impeding gas exchange performance or causing untoward effects. No difference in bleeding or thrombotic complication rate was observed; however, circuit occl...
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Pulmonary Source Type: research

Characteristics of Pediatric Extracorporeal Membrane Oxygenation Programs in the United States and Canada
The aim of this study was to evaluate the current infrastructure and practice characteristics of pediatric extracorporeal membrane oxygenation (ECMO) programs. A 40-question survey of center-specific demographics, practice structure, program experience, and support network utilized to cannulate and maintain a pediatric patient on ECMO was designed via a web-based survey tool. The survey was distributed to pediatric ECMO programs in the United States and Canada. Of the 101 centers that were identified to participate, 41 completed the survey. The majority of responding centers are university affiliated (73%) and have an inte...
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Pediatric Circulatory Support Source Type: research

Discharge and Readmissions After Ventricular Assist Device Placement in the US Pediatric Hospitals: A Collaboration in ACTION
Discharging children on ventricular assist device (VAD) support offers advantages for quality of life. We sought to describe discharge and readmission frequency in children on VAD support. All VAD-implanted patients aged 10–21 years at Advanced Cardiac Therapies Improving Outcomes Network (ACTION) centers were identified from the Pediatric Health Information System database (2009–2018). Discharge frequency on VAD was calculated. Patients discharged on VAD were compared with those not discharged. Freedom from readmission was assessed using the Kaplan–Meier method. A total of 298 VAD-implanted patients from...
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Pediatric Circulatory Support Source Type: research

Incidence and Etiology of System Exchanges in Patients Receiving Extracorporeal Membrane Oxygenation
Extracorporeal membrane oxygenation (ECMO) has established as a cornerstone therapy in severe acute respiratory distress syndrome and refractory hemodynamic failure. As circuit integrity is crucial for adequate organ support, component failure may necessitate a system exchange. In this retrospective study, incidence and etiology of system exchanges during applications of venovenous, venoarterial ECMO, and extracorporeal CO2 removal were examined. Sixty-three (44.4%) of 142 patients were affected by one or more exchanges, totaling 105 replaced circuits. The predominant exchange reason was clotting (n = 20), followed by hemo...
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Clinical Critical Care Source Type: research

Three-dimensional Video Assistance Improves Early Results in Minimally Invasive Mitral Valve Surgery
Abstract: Compared with the mid-sternotomy approach, minimally invasive mitral valve surgery is usually associated with longer surgical times. The increasing use of new technology has facilitated this procedure and shortened its duration, which may further improve surgical results. Since 2004, 152 patients have undergone minimally invasive mitral valve repair. Video-assisted 2D technology was used for the first 112 patients, while video-assisted 3D technology was used for the remaining 40 patients. All patients were divided into three groups: group 1 – the first 50 patients (learning curve using 2D technology); group...
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Clinical Cardiovascular Source Type: research

Peak Flow in Model Aorta Through Bi-Leaflet Mechanical Heart Valve with Varying Orientation
This study aims to numerically investigate the effect of bi-leaflet mechanical heart valve (BMHV) orientation on flow pattern in a realistic human aorta model with branches. The aorta model geometry is based on anatomical shape and dimensions involving aortic arch with twist and branches. Unsteady numerical simulations have been carried out to investigate the peak systolic flow in aorta through a BMHV installed at three different orientations, marked as 0°, 45°, and 90°. Velocity, vorticity, and strain fields were obtained in various cross sectional planes for all the cases to examine the spatial flow evolution...
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Biomedical Engineering Source Type: research

Left Ventricular Decompression by Transaortic Catheter Venting in Extracorporeal Membrane Oxygenation
Venoarterial extracorporeal membrane oxygenation (VA-ECMO) has been widely applied to patients with cardiogenic shock. Left ventricle (LV) decompression is important when LV distension develops with pulmonary edema. The purpose of this study was to present the results of transaortic catheter venting (TACV) performed during VA-ECMO. We retrospectively reviewed the medical records of 18 patients who underwent both VA-ECMO and TACV between January 2017 and December 2019. Venoarterial extracorporeal membrane oxygenation was applied uneventfully. Lactate level and norepinephrine requirement for patients of weaning success were ...
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Adult Circulatory Support Source Type: research

Gallium-67 Single-Photon Emission Computed Tomography Affects Management of Infections of Left Ventricular Assist Devices
We present a retrospective single-center study of 41 LVAD recipients who underwent Ga-SPECT-CT from January 2011 to June 2018 to determine whether Ga-SPECT-CT led to changes in antimicrobial therapy, LVAD revision or exchange, or application for 1A exception. The average age was 56.6 years, predominantly male (80.5%) and diabetic (68.3%), divided between ischemic (48.8%) and nonischemic (51.2%) cardiomyopathy. The majority had HeartMate II devices (82.9%). Device-related infections were classified as possible (12.2%), probable (36.6%), proven (36.6%), or rejected (14.6%). Sensitivity was 68.6% and specificity was 100%. Mos...
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Adult Circulatory Support Source Type: research

Thrombotic Risk of Rotor Speed Modulation Regimes of Contemporary Centrifugal Continuous-flow Left Ventricular Assist Devices
Contemporary centrifugal continuous-flow left ventricular assist devices (LVADs) incorporate dynamic speed modulation algorithms. Hemocompatibility of these periodic unsteady pump operating conditions has been only partially explored. We evaluated whether speed modulation induces flow alterations associated with detrimental prothrombotic effects. For this aim, we evaluated the thrombogenic profile of the HeartWare ventricular assist device (HVAD) Lavare Cycle (LC) and HeartMate3 (HM3) artificial pulse (AP) via comprehensive numerical evaluation of (i) pump washout, (ii) stagnation zones, (iii) shear stress regimens, and (i...
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Adult Circulatory Support Source Type: research

Function Follows Form: Modeling Ventricular Assist Device-Mediated Blood Flow
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Invited Commentary Source Type: research

Meet the Authors
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Meet the Authors Source Type: research

Left Ventricular Assist Device Flow Pattern Analysis Using a Novel Model Incorporating Left Ventricular Pulsatility
Our current understanding of flow through the circuit of left ventricular assist device (LVAD), left ventricle and ascending aorta remains incompletely understood. Computational fluid dynamics, which allow for analysis of flow in the cardiovascular system, have been used for this purpose, although current simulation models have failed to fully incorporate the interplay between the pulsatile left ventricle and continuous-flow generated by the LVAD. Flow-through the LVAD is dependent on the interaction between device and patient-specific factors with suboptimal flow patterns evoking increased risk of LVAD-related complicatio...
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Adult Circulatory Support Source Type: research

The Impact of COVID-19 on Heart Transplantations and Waitlist Additions in the United States
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Management of COVID-19 Patients Source Type: research

Applications of Bacterial Cellulose as a Natural Polymer in Tissue Engineering
Choosing the material with the best regeneration potential and properties closest to that of the extracellular matrix is one of the main challenges in tissue engineering and regenerative medicine. Natural polymers, such as collagen, elastin, and cellulose, are widely used for this purpose in tissue engineering. Cellulose derived from bacteria has excellent mechanical properties, high hydrophilicity, crystallinity, and a high degree of polymerization and, therefore, can be used as scaffold/membrane for tissue engineering. In the current study, we reviewed the latest trends in the application of bacterial cellulose (BC) poly...
Source: ASAIO Journal - July 1, 2021 Category: Medical Devices Tags: Review Article Source Type: research

Therapeutic Strategy in the era of MitraClip and Ventricular Assist Device
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Letters to the Editor Source Type: research

Carboxyhemoglobin Elevation, a Marker for Hemolysis, Is Common in Veno-venous Extracorporeal Membrane Oxygenation
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Letters to the Editor Source Type: research

Carboxyhemglobin and Drainage Pressure During Venovenous Extracorporeal Membrane Oxygenation
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Letters to the Editor Source Type: research

Pros and Cons of Different Types of Mechanical Circulatory Support Device in Case of Postinfarction Ventricular Septal Defect
We present a case of a large postinfarction VSD and the use of central venoarterial extracorporeal membrane oxygenation support to stabilize the patient until the VSD surgical repair. This case offers the opportunity to revise the indications and characteristics of different MCS, highlighting pros and cons of each one. (Source: ASAIO Journal)
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Case Reports Source Type: research

Use of a Minimally Invasive Approach to Correct Diffuse External Compression of the Left Ventricular Assist Device Outflow Graft
We describe this technique in two patients with diffuse ECOG in whom we found the method to be simple, relatively rapid, and very effective. (Source: ASAIO Journal)
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Case Reports Source Type: research

Feasibility of Lung Ultrasound to Monitor Aeration in Children Supported With Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Brief Communication Source Type: research

Carbon Dioxide Elimination During Veno-Venous Extracorporeal Membrane Oxygenation Weaning: A Pilot Study
Veno-venous extracorporeal membrane oxygenation (V-V ECMO) represents a component of the treatment strategy for severe respiratory failure. Clinical evidence on the management of the lung during V-V ECMO are limited just as the consensus regarding timing of weaning. The monitoring of the carbon dioxide (CO2) removal (V′CO2TOT) is subdivided into two components: the membrane lung (ML) and the native lung (NL) are both taken into consideration to evaluate the improvement of the function of the lung and to predict the time to wean off ECMO. We enrolled patients with acute respiratory distress syndrome (ARDS). The V&prim...
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Pulmonary Source Type: research

Bivalirudin in Pediatric Extracorporeal Membrane Oxygenation: Clarity or Confusion?
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Invited Commentary Source Type: research

Bivalirudin May Reduce the Need for Red Blood Cell Transfusion in Pediatric Cardiac Patients on Extracorporeal Membrane Oxygenation
We retrospectively compared anticoagulation with heparin and bivalirudin for 32 consecutive children under 18 years old during extracorporeal membrane oxygenation (ECMO) in our pediatric cardiac intensive care unit (PCICU). Between September 2015 and January 2018, 14 patients received heparin, 13 venoarterial (VA), and 1 venovenous (VV). From February 2018 to September 2019, 18 received bivalirudin (all VA). The mean (standard deviation [SD]) percentage of time with therapeutic activated partial thromboplastin time and activated clotting time was bivalirudin 54 (14%) and heparin 57 (11%), p = 0.4647, and percentage of time...
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Pediatric Circulatory Support Source Type: research

Systemic Hypertension in Pediatric Veno-Venous Extracorporeal Membrane Oxygenation
Systemic hypertension (HTN) is a recognized complication of veno-venous (VV) extracorporeal membrane oxygenation (ECMO) in children. We sought to determine the prevalence and associated features of HTN in a retrospective cohort of children (>1 year old) supported with VV ECMO from January 2015 to July 2019 at our institution. Patient and ECMO-related characteristics were reviewed, including intensive care unit (ICU) length of stay (LOS), ECMO duration, corticosteroids and nephrotoxic medication exposure, acute kidney injury (AKI), overall fluid balance, and transfusion data. We analyzed 23 children (43% female) with a m...
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Pediatric Circulatory Support Source Type: research

HVAD Usage and Outcomes in the Current Pediatric Ventricular Assist Device Field: An Advanced Cardiac Therapies Improving Outcomes Network (ACTION) Analysis
Advanced Cardiac Therapies Improving Outcomes Network (ACTION) is the first pediatric ventricular assist device (VAD) quality improvement network (46 centers). We aimed to describe outcomes with the HeartWare HVAD from ACTION centers. Patients with an HVAD implant in the ACTION registry (April 2018–April 2020) were analyzed. Baseline characteristics, adverse events, and survival were described. There were 50 patients implanted with a HVAD during the study period [36 cardiomyopathy, 8 congenital heart disease (CHD), and 6 other] and 21 (42%) had a prior sternotomy. Median age (range) was 12.9 years (3.4–19.1), b...
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Pediatric Circulatory Support Source Type: research

Dynamics of Blood Flows in Aortic Stenosis: Mild, Moderate, and Severe
This study systematically characterized the blood flow in mild, moderate, and severe AS. A series of large eddy simulations (LES) validated by particle image velocimetry were performed on physiologically representative AS models with a peak physiologic flow condition of 18 liter per minute. Time-accurate velocity fields, transvalvular pressure gradient, and laminar viscous—and turbulent (or Reynolds) shear stresses (RSSmax) were evaluated for each degree of severity. The peak velocities of mild, moderate, and severe AS were on the order of 2.0, 4.0, and 8.0 m/s, respectively. Jet velocity in severe AS was highly skew...
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Biomedical Engineering Source Type: research

Patient-Reported Issues Following Left Ventricular Assist Device Implantation Hospitalization
The purpose of this study was to explore the information reported by patients via a smartphone application (VAD Care App) used for left ventricular assist device (LVAD) self-care monitoring and reporting post hospital discharge. Specific aims were to examine the type and frequency of issues reported by patients through the app during months 1, 3, and 6 postdischarge. An exploratory-descriptive research design was used with 17 patients (12 males and 5 females) with durable LVADs, mean age of 48.6 ± 16 years. Data generated by the patients’ daily smartphone app usage more than 6 months were extracted from the se...
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Adult Circulatory Support Source Type: research

Impact of Preoperative Lymphopenia on Survival Following Left Ventricular Assist Device Placement
Lymphopenia has been implicated in poor outcomes in the heart failure population. However, the prognostic implication of lymphopenia in left ventricular assist device (LVAD) patients is unknown. We examine the impact of lymphopenia on all-cause mortality in this population over a 24-month period post-implantation. A total of 170 patients between June 2011 and July 2018 receiving permanent durable LVAD at a single center formed the study population. Criteria for lymphopenia on admission, defined as an absolute lymphocyte count (ALC) 4800/μl and nine with incomplete data. Survival across groups was compared with a Kaplan-...
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Adult Circulatory Support Source Type: research

Outcomes Following Left Ventricular Assist Device Exchange: Focus on the Impacts of Device Infection
In this study, we investigated the incidence and outcomes of LVAD exchange with the HeartMate II and HeartWare HVAD. Data were obtained from 677 patients who underwent CF-LVAD implantation between 2005 and 2016. Patients who underwent a device exchanged were included. The primary outcomes were length of hospital stay and mortality. Of the 677 patients included in this study, 72 (10.6%) required LVAD exchange. Thirty-day and 1-year mortality rates were comparable to primary LVAD implantation: 4.3% vs. 3.49%, p = 0.727 and 20.3% vs. 20.7%, p = 0.989, respectively. Thirty-one patients (4.5%) underwent exchange with ongoing in...
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Adult Circulatory Support Source Type: research

Hemodilution Increases the Susceptibility of Red Blood Cells to Mechanical Shear Stress During In Vitro Hemolysis Testing
The American Society for Testing and Materials (ASTM) F1841 standard for the assessment of hemolysis in blood pumps recommends using phosphate-buffered saline (PBS) for hemodilution to standardize hematocrit (HCT). However, PBS increases red blood cell mechanical fragility and hemolysis. Herein, we investigated diluents and dilutions during in vitro testing to reduce hemodilution bias when assessing hemolysis. Bovine blood was diluted with either PBS or PBS + 4/6 g% bovine serum albumin (BSA) to a 70/90% blood dilution, or to an HCT of 30% ± 2%, and pumped with the CentriMag or RotaFlow under hemodynamic conditions....
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Adult Circulatory Support Source Type: research

Comparison of Circulatory Unloading Techniques for Venoarterial Extracorporeal Membrane Oxygenation
This study aimed to quantitatively compare the hemodynamic differences between common circulatory unloading methods for ECMO. Ten circulatory unloading techniques were evaluated on a mock circulatory loop simulating acute LV failure supported by ECMO. Simulated unloading techniques included: surgical and percutaneous pulmonary artery (PA) venting, surgical left atrial venting, surgical and percutaneous LV venting, atrial septal defect, partial support ventricular assist device, intraaortic balloon pump, and temporary VAD with inline oxygenator (tVAD). The most LV unloading occurred with the surgically placed LV vent and tV...
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Adult Circulatory Support Source Type: research

Meet the Authors
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Meet the Authors Source Type: research

Gender Differences in Mortality After Left Ventricular Assist Device Implant: A Causal Mediation Analysis Approach
We used the International Society for Heart and Lung Transplantation (ISHLT) Registry for Mechanically Assisted Circulatory Support (IMACS) database to examine 1) gender differences in post-left ventricular assist device (LVAD) mortality in the contemporary era and 2) preimplant clinical factors that might mediate any observed differences. Adults who received continuous-flow (CF)-LVAD from January 2013 to September 2017 (n = 9,565, age: 56.2 ± 13.2 years, 21.6% female, 31.1% centrifugal pumps) were analyzed. An inverse probability weighted Cox proportional hazards model was used to estimate association of female gen...
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Adult Circulatory Support Source Type: research

Antifungal Prophylaxis for Adult Recipients of Veno-Venous Extracorporeal Membrane Oxygenation: A Cautionary Stance During the COVID-19 Pandemic
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: Management of COVID-19 Patients Source Type: research

Management of Adult Patients Supported with Venovenous Extracorporeal Membrane Oxygenation (VV ECMO): Guideline from the Extracorporeal Life Support Organization (ELSO)
Disclaimer: The use of venovenous extracorporeal membrane oxygenation (VV ECMO) in adults has rapidly increased worldwide. This ELSO guideline is intended to be a practical guide to patient selection, initiation, cannulation, management, and weaning of VV ECMO for adult respiratory failure. This is a consensus document which has been updated from the previous version to provide guidance to the clinician. (Source: ASAIO Journal)
Source: ASAIO Journal - June 1, 2021 Category: Medical Devices Tags: ELSO Guideline Source Type: research

Assessment of Severity and Implication of Aortic Insufficiency During Left Ventricular Assist Device Supports
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - May 1, 2021 Category: Medical Devices Tags: Letters to the Editor Source Type: research

Optimal Bridging Strategy Post-Ventricular Assist Device Implantation Remains Unclear
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - May 1, 2021 Category: Medical Devices Tags: Letters to the Editor Source Type: research

Extracorporeal Membrane Oxygenation as a Rescue Therapy for Postoperative Diastolic Dysfunction and Refractory Chylothorax
This is the first published case, as far as we know, of a term neonate with refractory chylothorax secondary to diastolic dysfunction in the cardiac postoperative period, where extracorporeal membrane oxygenation (ECMO) was used to improve the physiologic derangements, thus allowing resolution of the chylous effusion. The infant was prenatally diagnosed with d-transposition of the great arteries. He was started on prostaglandin infusion and underwent balloon atrial septostomy followed by arterial switch operation. After surgery, he developed anasarca and high-volume chylothorax that did not respond to medical management an...
Source: ASAIO Journal - May 1, 2021 Category: Medical Devices Tags: Case Reports Source Type: research

MitraClip Removal During Left Ventricular Assist Device Implantation
Mitral regurgitation (MR) is an important consequence of heart failure (HF) patients, which increases hospitalization and mortality rates. The MitraClip procedure is increasingly preferred for HF patients with obvious MR to improve MR and related symptoms. In some cases, patients may need further intervention such as left ventricular assist device implantation with the aim of improving progressive clinical deterioration caused by the progression of HF or mitral clip associated complications (i.e., detachment or mitral stenosis). This case study summarizes our two patients who received concomitant mitral clip removal and le...
Source: ASAIO Journal - May 1, 2021 Category: Medical Devices Tags: Case Reports Source Type: research

Purge Sidearm Damage: Achilles Heel of New Surgical Circulatory Support System?
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - May 1, 2021 Category: Medical Devices Tags: Brief Communication Source Type: research

Mobile Extracorporeal Membrane Oxygenation
To review our experience with mobile extracorporeal membrane oxygenation (ECMO). Mobile ECMO team included: ECMO-trained surgeon and intensivist, specialist nurse, and perfusionist. Patients were cannulated for venous-arterial (V-A) or venous-venous (V-V) ECMO, depending on clinical indication. Mobile transfers were carried out utilizing a Levitronics Centrimag centrifugal pump and Hico Variotherm 555 heater cooler. From October 2009 to May 2019, 571 patients, 185 (32%) neonates, 95 (17%) pediatric, and 291 (51%) adults, underwent mobile ECMO transfer. Four hundred fifty-three (79%) transfers were completed by road, 76 (13...
Source: ASAIO Journal - May 1, 2021 Category: Medical Devices Tags: Pediatric Circulatory Support Source Type: research

Time in Therapeutic Range for Bivalirudin Among Pediatric Ventricular Assist Device Recipients
We report very good %TTR for bivalirudin both in the first 2 weeks post implant and this improved over the duration of support. Because %TTR reflects the degree of safety and efficacy in chronic anticoagulation, this relatively high %TTR among a diverse, often critically ill cohort suggests that bivalirudin may be a promising agent. Although this study was underpowered to comprehensively evaluate adverse events on bivalirudin, this represents an important next step for larger scale study. (Source: ASAIO Journal)
Source: ASAIO Journal - May 1, 2021 Category: Medical Devices Tags: Pediatric Circulatory Support Source Type: research

Natural History of Patients Diagnosed with Cardiac Sarcoidosis at Left Ventricular Assist Device Implantation or Cardiac Transplantation
To our knowledge, natural history has not been reported for cardiac sarcoidosis (CS) diagnosed by pathologic evaluation of the apical core at left ventricular assist device (LVAD) implantation or cardiac transplantation. We retrospectively identified 232 consecutive patients meeting CS criteria. Of these patients, 54 were diagnosed by pathologic confirmation of CS, 10 after evaluation of the apical core (LVAD implant) or explanted heart (transplant). We compared clinical characteristics at initial evaluation and outcomes for these 10 patients with those of 10 patients with known CS before LVAD implant/transplant. In the st...
Source: ASAIO Journal - May 1, 2021 Category: Medical Devices Tags: Clinical Cardiovascular Source Type: research