Erratum: Ortiz et al, Left Ventricular Flow Dynamics with the HeartMate3 Left Ventricular Assist Device: Effect of Inflow Cannula Position and Speed Modulation
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - February 27, 2022 Category: Medical Devices Tags: Erratum Source Type: research
Voriconazole Sequestration During Extracorporeal Membrane Oxygenation for Invasive Lung Aspergillosis: A Case Report
We report on the therapeutic drug monitoring and clinical evolution of a patient treated with voriconazole for invasive pulmonary aspergillosis while receiving ECMO therapy. Voriconazole trough levels were persistently low ( (Source: ASAIO Journal)
Source: ASAIO Journal - February 27, 2022 Category: Medical Devices Tags: Case Reports Source Type: research
Veno-Venous Extracorporeal Rewarming Using Dual-Lumen Cannula in Accidental Hypothermia
We report a case of rewarming using veno-venous dual-lumen cannula as an alternative to veno-arterial support with full recovery and normal neurologic examination. In centers where extracorporeal membrane oxygenation is available, rewarming using veno-venous dual-lumen extracorporeal support may be a useful strategy to mitigate the risks associated with veno-arterial extracorporeal support. (Source: ASAIO Journal)
Source: ASAIO Journal - February 27, 2022 Category: Medical Devices Tags: Case Reports Source Type: research
Modified AngioVac System use With Extracorporeal Membrane Oxygenation in a Child With Fontan Thrombosis
We report modified use of the second-generation AVS with concurrent venoarterial extracorporeal membrane oxygenation (VA-ECMO) in a 10-year-old, 23 kg patient with failing Fontan circulation due to acute-on-chronic Fontan and PA thrombosis. Emergent femoral VA-ECMO was initiated for profound hypoxemia during cardiac catheterization. Fluoroscopy-guided thrombo-embolectomy was performed with AVS components. A two-venous limb inflow cannulation strategy was used; the AngioVac cannula (AVC) was positioned in the central PA and joined to the existing ECMO venous-limb. Thrombus extraction proceeded by clamping the ECMO venous-...
Source: ASAIO Journal - February 27, 2022 Category: Medical Devices Tags: Case Reports Source Type: research
Extracorporeal Membrane Oxygenation Bridge to Heart-Lung Transplantation
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - February 27, 2022 Category: Medical Devices Tags: Brief Communication Source Type: research
Management of Circuit Air in Extracorporeal Membrane Oxygenation: A Single Center Experience
We report our institutions’ experience in the management of circuit air in Cardiohelp HLS ECMO system. Between October 2009 and July 2020, 4 out of 116 patients developed gas bubbles in ECMO circuit or systemic gas embolism. The clinical characteristics of these patients, source of air, presence of arterial air or pump airlock, cardiorespiratory status during the event, techniques employed to re-establish flow, ECMO downtime, neurologic, and other clinical outcomes were reported. In all cases, the source of air was located, with three of them being on the venous side of the circuit. Centrifugal pump airlock with cessatio...
Source: ASAIO Journal - February 27, 2022 Category: Medical Devices Tags: How to do it Article Source Type: research
Detecting High-Resolution Intramural Vascular Wall Strain Signals Using DICOM Data
Maintaining dialysis vascular access is a source of considerable morbidity in patients with end-stage renal disease (ESRD). High-resolution radiofrequency (RF) ultrasound vascular strain imaging has been applied experimentally in the vascular access setting to assist in diagnosis and management. Unfortunately, high-resolution RF data are not routinely accessible to clinicians. In contrast, the standard DICOM formatted B-mode ultrasound data are widely accessible. However, B-mode, representing the envelope of the RF signal, is of much lower resolution. If strain imaging could use open-source B-mode data, these imaging techn...
Source: ASAIO Journal - February 27, 2022 Category: Medical Devices Tags: Renal/Extracorporeal Blood Treatment Source Type: research
Recent Era Outcomes of Mechanical Circulatory Support in Children With Congenital Heart Disease as a Bridge to Heart Transplantation
The objective of the study is to compare the clinical characteristics, risk factors, and overall survival (waitlist and posttransplant) outcomes in children with congenital heart disease (CHD) bridged to transplantation with either a ventricular assist device (VAD) versus extracorporeal membrane oxygenation (ECMO) versus no mechanical circulatory support (MCS) in the recent era. The study included 2,899 primary heart transplantations in patients (Source: ASAIO Journal)
Source: ASAIO Journal - February 27, 2022 Category: Medical Devices Tags: Pediatric Circulatory Support Source Type: research
Extracorporeal Membrane Oxygenation for Pediatric Burn Patients: Is Management Improving Over Time?
Over the last few decades, extracorporeal membrane oxygenation (ECMO) has become a lifesaving modality for patients with severe respiratory failure following burn injury. With the advancement in critical care and ECMO management, this study aims to analyze the outcomes of ECMO in pediatric burn patients. The Extracorporeal Life Support Organization database was queried from 1999 to 2018 for patients 18 years old and under with a burn injury. The data were divided into two decades, the first (1999–2008) and the second (2009–2018), for analysis of background characteristics and clinical outcomes. Ninety-five patients met...
Source: ASAIO Journal - February 27, 2022 Category: Medical Devices Tags: Pediatric Circulatory Support Source Type: research
Cyclohexanone Exposure in Children on Extracorporeal Membrane Oxygenation Support
The aim of this study was to determine if plasma cyclohexanone and metabolites are associated with clinical outcomes of children on extracorporeal membrane oxygenation (ECMO) support. We performed a secondary analysis of a prospective observational study of children on ECMO support at two academic centers between July 2010 and June 2015. We measured plasma cyclohexanone and metabolites on the first and last days of ECMO support. Unfavorable outcome was defined as in-hospital death or discharge Pediatric Cerebral Performance Category score> 2 or decline ≥ 1 from baseline. Among 90 children included, 49 (54%) had unfavorab...
Source: ASAIO Journal - February 27, 2022 Category: Medical Devices Tags: Pediatric Circulatory Support Source Type: research
Factors Associated With Initiation of Extracorporeal Cardiopulmonary Resuscitation in the Pediatric Population: An International Survey
Although extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly utilized in the pediatric critical care environment, our understanding regarding pediatric candidacy for ECPR remains unknown. Our objective is to explore current practice and indications for pediatric ECPR. Scenario-based, self-administered, online survey, evaluating clinical determinants that may impact pediatric ECPR initiation with respect to four scenarios: postoperative cardiac surgery, cardiac failure secondary to myocarditis, septic shock, and chronic respiratory failure in a former preterm child. Responders are pediatric critical care phy...
Source: ASAIO Journal - February 27, 2022 Category: Medical Devices Tags: Pediatric Circulatory Support Source Type: research
Fluid Balance Management Informs Renal Replacement Therapy Use During Pediatric Extracorporeal Membrane Oxygenation: A Survey Report From the Kidney Intervention During Extracorporeal Membrane Oxygenation Group
Fluid overload (FO) and acute kidney injury (AKI) occur commonly in children supported with extracorporeal membrane oxygenation (ECMO). Continuous renal replacement therapy (CRRT) may be used to manage AKI and FO in children on ECMO. In 2012, our group surveyed ECMO centers to begin to understand the practice patterns around CRRT and ECMO. Since then, more centers are initiating ECMO for increasingly diverse indications and an increased volume of research quantifies the detrimental impacts of AKI and FO. We, therefore, investigated practice patterns of CRRT utilization during ECMO in children. A multi-point survey instrume...
Source: ASAIO Journal - February 27, 2022 Category: Medical Devices Tags: Pediatric Circulatory Support Source Type: research
The Effect of Sodium Thiosulfate on Coronary Artery Calcification in Hemodialysis Patients
This study aimed to effectively control the disease process of hemodialysis outpatients. Hemodialysis secondary hyperparathyroidism patients were randomly divided into the control group and treatment group. The control group was treated with routine treatment, and the treatment group was treated with sodium thiosulfate based on the control group. The changes of serum calcium, phosphorus, whole parathyroid hormone, calcium-phosphorus product and coronary artery calcification (CAC) score, as well as the relief of clinical symptoms, postoperative complications and recurrence in the preoperative and postoperative periods were ...
Source: ASAIO Journal - February 27, 2022 Category: Medical Devices Tags: Clinical Cardiovascular Source Type: research
Primary Graft Dysfunction in Heart Transplant Recipients—Risk Factors and Longitudinal Outcomes
Before the 33rd Annual International Society for Heart and Lung Transplantation conference, there was significant intercenter variability in definitions of primary graft dysfunction (PGD). The incidence, risk factors, and outcomes of consensus-defined PGD warrant further investigation. We retrospectively examined 448 adult cardiac transplant recipients at our institution from 2005 to 2017. Patient and procedural characteristics were compared between PGD cases and controls. Multivariable logistic regression was used to model PGD and immediate postoperative high-inotrope requirement for hypothesized risk factors. Patients we...
Source: ASAIO Journal - February 27, 2022 Category: Medical Devices Tags: Clinical Cardiovascular Source Type: research
Potential Factors for Poor Reproducibility of In Vitro Hemolysis Testing
In vitro testing of hemolysis is essential for the validation and development of ventricular assist devices. However, as many factors influence hemolysis, such tests’ inter- and intralaboratory reproducibility is poor. In this work, CentriMag blood pumps were used to conduct a hemolysis study according to ASTM F1841 with blood from 23 bovine donors. Complementary blood analysis, including cell count, plasma composition, and viscosity, was performed to identify factors relevant to the variability of hemolysis testing results. Three strategies were tested to improve reproducibility: albumin supplementation, maintaining glu...
Source: ASAIO Journal - February 27, 2022 Category: Medical Devices Tags: Biomedical Engineering Source Type: research
