Pediatric Extracorporeal Cardiopulmonary Resuscitation ELSO Guidelines: Erratum
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - June 30, 2022 Category: Medical Devices Tags: Errata Source Type: research

Extracorporeal Life Support Organization (ELSO): Guidelines For Pediatric Cardiac Failure: Erratum
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - June 30, 2022 Category: Medical Devices Tags: Errata Source Type: research

Extracorporeal Life Support Organization (ELSO) Guidelines For Follow-Up After Neonatal And Pediatric Extracorporeal Membrane Oxygenation: Erratum
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - June 30, 2022 Category: Medical Devices Tags: Errata Source Type: research

Polyuria due to Pressure Natriuresis in Venoarterial Extracorporeal Membrane Oxygenation
We report a case of a 40-year-old woman who developed profound polyuria (>25 L urine output) immediately after initiation of venoarterial (VA) extracorporeal membrane oxygenation (ECMO). Investigations into the cause determined the polyuria was due to marked natriuresis (>85 g of sodium excreted in 1 day). This natriuresis persisted despite low cardiac filling pressures and high-negative ECMO venous pressures, suggesting clinical hypovolemia due to pressure natriuresis from locally high pressures at the renal artery due to arterial ECMO inflow. As ECMO flows were decreased, polyuria and natriuresis resolved. To our kno...
Source: ASAIO Journal - June 30, 2022 Category: Medical Devices Tags: Case Reports Source Type: research

First-in-man Implantation of a Cardiac Microcurrent Device for Chronic Systolic Heart Failure
Current therapies significantly improve survival and clinical endpoints in patients suffering from chronic heart failure with reduced ejection fraction (HFrEF), but most are not sufficient to reverse adverse remodeling and improve myocardial contractility. Herein, we report the first-in-man experience with a novel fully implantable device for cardiac electrical microcurrent (C-MIC) application. A 79-year-old man suffering from HFrEF (dilated cardiomyopathy, NYHA class III, left ventricular ejection fraction 30%) successfully underwent implantation of the C-MIC device through left anterolateral thoracotomy. At 30-day follow...
Source: ASAIO Journal - June 30, 2022 Category: Medical Devices Tags: Case Reports Source Type: research

Early Neurological Pupil Index Assessment to Predict Outcome in Cardiac Arrest Patients Undergoing Extracorporeal Membrane Oxygenation
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - June 30, 2022 Category: Medical Devices Tags: Brief Communications Source Type: research

A Single-center Experience of CardioMEMS in Patients With Left Ventricular Assist Devices
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - June 30, 2022 Category: Medical Devices Tags: Brief Communications Source Type: research

Impella CP to Impella 5.5 Uninterrupted Upgrade Using a Double Device Technique
For the first time, we present a novel technique that enables the exchange of the Impella CP (Abiomed Inc., Danvers, Massachusetts, USA) to the Impella 5.5 (Abiomed Inc.) with no interruption of mechanical support in patients with minimal left ventricular reserve. Specifically, the aortic valve is crossed with the Impella 5.5 whereas the Impella CP is still functioning within the left ventricle. The Impella 5.5 is then initiated, and the Impella CP is weaned. Finally, the Impella CP is pulled out into the descending aorta. This exchange provides continuous support with no hemodynamic disarrangement. (Source: ASAIO Journal)
Source: ASAIO Journal - June 30, 2022 Category: Medical Devices Tags: How to do it Article Source Type: research

Mechanisms of Blood pH Changes in Venovenous Extracorporeal Membrane Systems: Roles of Hemoglobin-Ion Binding and Donnan Equilibrium
An equilibrium model was developed to understand interrelated, physicochemical mechanisms leading to blood pH and electrolyte distribution changes in patients because of venovenous extracorporeal membrane oxygenation (ECMO) and carbon dioxide removal. The model consists of plasma and red cell compartments between which water and small ions can move to establish an equilibrium state. Governing forces are as follows: 1) ionic electroneutrality in each compartment; 2) osmotic equilibrium between compartments; 3) mass balance of small ions other than bicarbonate; 4) oxygen (O2)-dependent hemoglobin (Hb)-Cl binding in red cells...
Source: ASAIO Journal - June 30, 2022 Category: Medical Devices Tags: Renal/Extracorporeal Blood Treatment Source Type: research

Active Circulating Blood Volume During Hemodialysis: A Bench Model
This study demonstrates the ability to accurately measure ACBV on the bench. (Source: ASAIO Journal)
Source: ASAIO Journal - June 30, 2022 Category: Medical Devices Tags: Renal/Extracorporeal Blood Treatment Source Type: research

Meet the Authors
No abstract available (Source: ASAIO Journal)
Source: ASAIO Journal - June 30, 2022 Category: Medical Devices Tags: Meet the Authors Source Type: research

Electrical Impedance as a Noninvasive Metric of Quality in Allografts Undergoing Normothermic Ex Vivo Lung Perfusion
Ex vivo lung perfusion (EVLP) increases the pool of suitable organs for transplant by facilitating assessment and repair at normothermia, thereby improving identification of quality of marginal organs. However, there exists no current objective approach for assessing total organ edema. We sought to evaluate the use of electrical impedance as a metric to assess total organ edema in lungs undergoing EVLP. Adult porcine lungs (40 kg) underwent normothermic EVLP for 4 hours. To induce varying degrees of lung injury, the allografts were perfused with either Steen, a modified cell culture media, or 0.9% normal saline. Physiolo...
Source: ASAIO Journal - June 30, 2022 Category: Medical Devices Tags: Pulmonary Source Type: research

Acute Kidney Injury and Fluid Overload in Pediatric Extracorporeal Cardio-Pulmonary Resuscitation: A Multicenter Retrospective Cohort Study
Acute kidney injury (AKI) and fluid overload (FO) are common complications of extracorporeal membrane oxygenation (ECMO). The purpose of this study was to characterize AKI and FO in children receiving extracorporeal cardiopulmonary resuscitation (eCPR). We performed a multicenter retrospective study of children who received eCPR. AKI was assessed during ECMO and FO defined as (Source: ASAIO Journal)
Source: ASAIO Journal - June 30, 2022 Category: Medical Devices Tags: Pediatric Circulatory Support Source Type: research

Hepatic Function in Premature Lambs Supported by the Artificial Placenta and Total Parenteral Nutrition
This study evaluates hepatic outcomes after AP support with total parenteral nutrition (TPN) administration. Premature lambs (116–121 days estimated gestational age; term = 145) were cannulated for 7 days of AP support. Lambs received TPN with SMOFlipid (n = 7) or Intralipid (n = 5). Liver function and injury were compared between the two groups biochemically and histologically. Groups were compared by ANOVA with Tukey’s multiple comparisons or linear-mixed effects models. From baseline to day 7, total bilirubin (Intralipid 2.6 ± 2.3 to 7.9 ± 4.4 mg/dl; SMOFlipid 0.3 ± 0.1 to 5.5 ± 2.3 mg/dl), a...
Source: ASAIO Journal - June 30, 2022 Category: Medical Devices Tags: Pediatric Circulatory Support Source Type: research

Fabrication and Characterization of Tissue-Mimicking Phantoms for Ultrasound-Guided Cannulation Training
Tissue-mimicking materials (TMMs) have been investigated and used for decades as imaging phantoms in various medical applications. They are designed and fabricated to replicate certain biological tissue characteristics, a process often dictated by the target application. Moreover, TMMs have been utilized in some medical procedural training requiring the use of imaging modalities. One potential application for TMMs is ultrasound-guided cannulation training. Cannulation is a procedure that requires a level of dexterity to gain vascular access using ultrasound guidance while avoiding complications like vessel laceration and b...
Source: ASAIO Journal - June 30, 2022 Category: Medical Devices Tags: Clinical Critical Care Source Type: research