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Patients with periodontitis are at a higher risk of stroke: A Taiwanese cohort study
CONCLUSION: Therefore, this study suggests a high risk of stroke in patients with periodontitis.PMID:36000972 | DOI:10.1097/JCMA.0000000000000797
Source: Atherosclerosis - August 24, 2022 Category: Cardiology Authors: Pei-Wei Hsu Yen-Wen Shen Syamsiah Syam Wen-Miin Liang Trong-Neng Wu Jui-Ting Hsu Lih-Jyh Fuh Source Type: research

New-Onset Atrial Fibrillation Is a Risk Factor of Ischemic Stroke in Chronic Obstructive Pulmonary Disease
In conclusion, COPD patients suffering from new-onset AF had an increased incidence of IS in the population observation study. New-onset AF was an omit risk factor for IS in COPD in the Chinese population.PMID:35206997 | DOI:10.3390/healthcare10020381
Source: Atherosclerosis - February 25, 2022 Category: Cardiology Authors: Chi-Chun Liu Yu-Hsuan Chen Yin-Han Chang Wu-Chien Chien Hui-Chen Lin Chun-Gu Cheng Chun-An Cheng Source Type: research

Continuation or discontinuation of oral anticoagulants after HAS-BLED scores increase in patients with atrial fibrillation
ConclusionsFor patients whose HAS-BLED scores increased to  ≥ 3, the continuation of OACs was associated with better clinical outcomes. An increased HAS-BLED score in anticoagulated AF patients may not be the only reason to withhold OACs, but reminds physicians to correct modifiable bleeding risk factors and follow up patients more closely.Graphical abstractAssociations between Continuation or Discontinuation of Oral Anticoagulants and Risks of Clinical Outcomes after HAS-BLED Scores IncreasedAF atrial fibrillation;aHR adjusted hazard ratio;ICH intra-cranial hemorrhage;OACs oral anticoagulants
Source: Clinical Research in Cardiology - January 1, 2022 Category: Cardiology Source Type: research

The risk and timing of acute ischemic stroke after electrical cardioversion for atrial fibrillation in Taiwan: A nationwide population-based cohort study
There is a positive association between electrical cardioversion (ECV) and acute ischemic stroke (AIS). Although 4  weeks of anticoagulation therapy after ECV in atrial fibrillation (AF) patients is generally suggested by current guidelines to reduce the risk of AIS, limited studies have been conducted in Asian populations to determine the risk and timing of AIS after ECV for AF in recent years. Therefore, we aim to use the National Health Insurance Research Database (NHIRD) in Taiwan to determine the risk and timing of AIS after ECV for AF.
Source: International Journal of Cardiology - December 23, 2021 Category: Cardiology Authors: Chih-Kang Huang, Jen-Chun Wang, Chi-Hsiang Chung, Sy-Jou Chen, Wen-I Liao, Wu-Chien Chien Source Type: research

Continuation or discontinuation of oral anticoagulants after HAS-BLED scores increase in patients with atrial fibrillation
ConclusionsFor patients whose HAS-BLED scores increased to  ≥ 3, the continuation of OACs was associated with better clinical outcomes. An increased HAS-BLED score in anticoagulated AF patients may not be the only reason to withhold OACs, but reminds physicians to correct modifiable bleeding risk factors and follow up patients more closely.Graphical abstractAssociations between Continuation or Discontinuation of Oral Anticoagulants and Risks of Clinical Outcomes after HAS-BLED Scores IncreasedAF atrial fibrillation;aHR adjusted hazard ratio;ICH intra-cranial hemorrhage;OACs oral anticoagulants
Source: Clinical Research in Cardiology - March 11, 2021 Category: Cardiology Source Type: research

Thromboembolic events in atrial fibrillation: Different level of risk and pattern between peripheral artery disease and coronary artery disease.
CONCLUSIONS: PAD or CAD in patients with AF did not contribute equally to the risk prediction and presentation of IS and STE. Patients with polyvascular disease should be considered at higher risk than those with either condition. PMID: 33518472 [PubMed - as supplied by publisher]
Source: Archives of Cardiovascular Diseases - January 28, 2021 Category: Cardiology Authors: Lin YS, Wu VC, Chen YL, Liu CH, Chen HC, Lee WC, Yang TY, Aboyans V, Chen MC Tags: Arch Cardiovasc Dis Source Type: research

Effectiveness and Safety of Direct Oral Anticoagulants in an Asian Population with Atrial Fibrillation Undergoing Dialysis: A Population-Based Cohort Study and Meta-Analysis
ConclusionsDOACs did not provide benefit over warfarin regarding effectiveness and safety in AF patients undergoing dialysis. The use of OAC was not associated with a lower risk of IS/SE in ESRD AF patients when compared to those without OAC use.
Source: Cardiovascular Drugs and Therapy - November 19, 2020 Category: Cardiology Source Type: research

Oral Anticoagulants and Antiplatelet Agents in Atrial Fibrillation Patients with Concomitant Critical Limb Ischemia: A nationwide cohort study
ConclusionsDOAC was associated with a significantly lower risk of composite net-clinical-benefit outcome than either warfarin or APT in AF patients with concomitant CLI. Further prospective study is necessary to validate the findings in the future.
Source: Canadian Journal of Cardiology - February 19, 2020 Category: Cardiology Source Type: research

Adverse Outcomes Associated with Pre-Existing and New-Onset Atrial Fibrillation in Patients with Acute Coronary Syndrome: A Retrospective Cohort Study
ConclusionsNew-onset AF during ACS was associated with a significantly increased risk of adverse outcomes, especially in the elderly patients.
Source: Cardiology and Therapy - April 16, 2019 Category: Cardiology Source Type: research

Antithrombotic Treatment May Reduce Mortality Among New-Onset Atrial Fibrillation Patients with Gray-Zone Risk of Stroke.
This study aimed to evaluate whether gray zone AF patients could benefit from reduced all-cause mortality under antithrombotic treatment. This was a longitudinal cohort study performed using data from claim forms submitted to the Taiwan Bureau of National Health Insurance from January 2000 to December 2011. The new-onset AF patients consisted of a gray zone cohort with a total of 1237 patients being enrolled. The primary outcome was all-cause mortality between 2001 and 2011. Patients in the gray zone receiving antithrombotic treatment had a significant reduction in all-cause mortality [hazard ratio (HR): 0.21; 95% confiden...
Source: International Heart Journal - February 13, 2019 Category: Cardiology Tags: Int Heart J Source Type: research

Monotherapy of aspirin or warfarin for prevention of ischemic stroke in low-risk atrial fibrillation: A Easter Asian population-based study.
CONCLUSIONS: Warfarin is suggested to be prescribed in preventing ischemic stroke for low-stroke-risk atrial fibrillation patients with hypertension and hyperlipidemia. PMID: 29718533 [PubMed - as supplied by publisher]
Source: Cardiology Journal - May 2, 2018 Category: Cardiology Authors: Liu CY, Chen HC Tags: Cardiol J Source Type: research

The effectiveness and safety of low-dose rivaroxaban in Asians with non-valvular atrial fibrillation
The objective of the study is to compare the effectiveness and safety of low-dose rivaroxaban to those of warfarin among Asians with NVAF.
Source: International Journal of Cardiology - March 14, 2018 Category: Cardiology Authors: Hsin-Fu Lee, Yi-Hsin Chan, Hui-Tzu Tu, Chi-Tai Kuo, Yung-Hsin Yeh, Shang-Hung Chang, Lung-Sheng Wu, Lai-Chu See Source Type: research

Oral Anticoagulation in Very Elderly Patients with Atrial Fibrillation - A Nationwide Cohort Study.
Conclusions -Among AF patients age ≥90 years, warfarin was associated with a lower risk of ischemic stroke and positive NCB. Compared to warfarin, NOACs were associated with a lower risk of ICH. Thus, OACs may still be considered as thromboprophylaxis for elderly patients with NOACs being as the more favorable choice. PMID: 29490992 [PubMed - as supplied by publisher]
Source: Circulation - February 28, 2018 Category: Cardiology Authors: Chao TF, Liu CJ, Lin YJ, Chang SL, Lo LW, Hu YF, Tuan TC, Liao JN, Chung FP, Chen TJ, Lip GYH, Chen SA Tags: Circulation Source Type: research

Aplastic Anemia and Risk of Incident Atrial Fibrillation 　- A Nationwide Cohort Study.
CONCLUSIONS: Patients with AA could have an elevated risk for AF. The mortality risk increased further for those who develop AF. PMID: 29459495 [PubMed - as supplied by publisher]
Source: Circulation Journal - February 16, 2018 Category: Cardiology Authors: Hu WS, Sung FC, Lin CL Tags: Circ J Source Type: research

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