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Infectious Disease: Epidemics

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Total 445 results found since Jan 2013.

Prevalence and Risk Factors of Prehypertension and Hypertension in Southern China
ConclusionsPrehypertension and hypertension are epidemic in southern China. Further studies are needed to explore an indicator that can represent the visceral fat accurately and has a close relationship with cardiovascular disease.
Source: PLoS One - January 16, 2017 Category: Biomedical Science Authors: Lihua Hu Source Type: research

Dangerous Fruit: Mystery of Deadly Outbreaks in India Is Solved
Researchers had suspected that heat stroke, infections or pesticides were behind a disease that killed about 40 percent of children affected, but it seems lychees were to blame.
Source: NYT Health - January 31, 2017 Category: Consumer Health News Authors: ELLEN BARRY Tags: Litchis Muzaffarpur, India Epidemics The Lancet Srikantiah, Padmini Source Type: news

Contribution of Maladaptive Adipose Tissue Expansion to Development of Cardiovascular Disease.
Authors: Jia G, Jia Y, Sowers JR Abstract The overweight and obesity epidemic has led to an increase in the metabolic syndrome and associated cardiovascular disease (CVD). These abnormalities include insulin resistance, type 2 diabetes mellitus, vascular stiffness, hypertension, stroke, and coronary heart disease. Visceral white adipocyte tissue (WAT) expansion and associated fibrosis/stiffness of WAT promote insulin resistance and CVD through increases in proinflammatory adipokines, oxidative stress, activation of renin-angiotensin-aldosterone system, dysregulation of adipocyte apoptosis and autophagy, dysfunction...
Source: Comprehensive Physiology - February 1, 2017 Category: Physiology Tags: Compr Physiol Source Type: research

Nanocarriers as treatment modalities for hypertension.
Authors: Alam T, Khan S, Gaba B, Haider MF, Baboota S, Ali J Abstract Hypertension, a worldwide epidemic at present, is not a disease in itself rather it is an important risk factor for serious cardiovascular disorders including myocardial infarction, stroke, heart failure, and peripheral artery disease. Though numerous drugs acting via different mechanism of action are available in the market as conventional formulations for the treatment of hypertension but they face substantial challenges regarding their bioavailability, dosing and associated adverse effects which greatly limit their therapeutic efficacies. Vari...
Source: Drug Delivery - February 8, 2017 Category: Drugs & Pharmacology Tags: Drug Deliv Source Type: research

New drugs for Diabetes: Finally safety and cardiovascular efficacy
Diabetes mellitus has emerged as the epidemic of the modern age [1]. Concomitant with this, we have witnessed a rise in the complications of this condition, with diabetes now the number one cause of end stage renal failure in developed nations and ~75% of deaths in the overall diabetic population being related to cardiovascular disease, primarily stroke, myocardial infarction and heart failure [2].
Source: Trends in Cardiovascular Medicine - February 23, 2017 Category: Cardiology Authors: Kim A. Connelly Source Type: research

New Evidence Linking Obesity and Food Addiction
Obesity rates have skyrocketed over the past few decades. In the United States, approximately 35% of adults are now considered obese, with more than 60% categorized as overweight (1). The health consequences of obesity are substantial. Obesity increases the risk of developing several debilitating conditions, such as diabetes, heart disease, stroke, and mental illness. Because the global obesity epidemic is generally believed to be caused by excessive caloric intake, there has been increasing interest in understanding the neurobiological mechanisms contributing to overeating, defined as continued eating in the absence of me...
Source: Biological Psychiatry - April 11, 2017 Category: Psychiatry Authors: Elise C. Cope, Elizabeth Gould Tags: Commentary Source Type: research

Zika associated Guillain-Barre syndrome in the United States (P2.327)
Conclusions:Zika can induce GBS after a brief viral illness. Neuropathy can be a mixture of demyelinating and axonal. Dysautonomia may also be present including severe dysphagia, orthostatics and retention.Zika RNA has a short detection window in serum and CSF making a diagnosis time sensitive. Serological assays using IgM and IgG cross-react with other flaviviruses making them unable to differentiate between recent Zika exposure and cross reactivity with Dengue and Chikungunya. Our pt likely had prior exposure to Dengue, being from an endemic area. Prior Dengue exposure may possibly modulate the response to Zika via antib...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Tantillo, G., Sclar, G., Vasa, C., Shin, S., Sivak, M. Tags: Zika, Chikungunya, West Nile Virus, and Other Viral Infections I Source Type: research

Britain faces epidemic of strokes as we live longer
The number of Britons suffering a stroke is expected to increase 44 per cent by 2035, significantly higher than the European average of 34 per cent, and driven by an ageing population.
Source: the Mail online | Health - May 11, 2017 Category: Consumer Health News Source Type: news

Melanocortin neurons: multiple routes to regulation of metabolism.
Abstract The burden of disability, premature death, escalating health care costs and lost economic productivity due to obesity and its associated complications including hypertension, stroke, cardiovascular disease and type 2 diabetes is staggering [1, 2]. A better understanding of metabolic homeostatic pathways will provide us with insights into the biological mechanisms of obesity and how to fundamentally address this epidemic [3-6]. In mammals, energy balance is maintained via a homeostatic system involving both peripheral and central melanocortin systems; changes in body weight reflect an unbalance of the ener...
Source: Biochimica et Biophysica Acta - May 9, 2017 Category: Biochemistry Authors: Shen WJ, Yao T, Kong X, Williams KW, Liu T Tags: Biochim Biophys Acta Source Type: research

Chris Cornell: When Suicide Doesn't Make Sense
By Julie A. Fast Sometimes, people commit suicide and it does make some sense. It’s scary and upsets our world, but on a basic level we think we understand. The suicide of Robin Williams comes to mind. He had a history of depression and his health was failing. Oh how we all wish he could have found more help, but I don’t think it was as much surprising as it was devastating and sad for the millions who loved him when he died. Then there are suicides that make no sense. They don’t fit in the current life of the person or fit what the person is actually saying about life in public. The partner or other love...
Source: Healthy Living - The Huffington Post - May 18, 2017 Category: Consumer Health News Source Type: news

Overfed and Underfed: Global Food Extremes
The international community of nations has made commitments to eliminate hunger, achieve food security and improved nutrition by 2030 and also to promote and protect health through nutritious diet, healthy eating and increased physical activity. Credit: IPSBy Joseph ChamieNEW YORK, Jun 12 2017 (IPS)Global food extremes of chronic undernourishment and obesity have brought about a bipolar world of hundreds of millions of underfed and overfed people. Of the world’s population of 7.5 billion the proportions suffering from chronic undernourishment and those afflicted by obesity are similar, approximately 11 percent or togethe...
Source: IPS Inter Press Service - Health - June 12, 2017 Category: International Medicine & Public Health Authors: Joseph Chamie Tags: Development & Aid Food & Agriculture Global Headlines Health Poverty & SDGs Regional Categories Source Type: news

Editorial commentary: New drugs for diabetes: Finally safety and cardiovascular efficacy
Diabetes mellitus has emerged as the epidemic of the modern age [1]. Concomitant with this, we have witnessed a rise in the complications of this condition, with diabetes now the number one cause of end stage renal failure in developed nations and ~75% of deaths in the overall diabetic population being related to cardiovascular disease, primarily stroke, myocardial infarction and heart failure [2].
Source: Trends in Cardiovascular Medicine - February 24, 2017 Category: Cardiology Authors: Kim A. Connelly Source Type: research

Hopkins Nursing—Dean on Chronic Disease / Pediatrics
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Source: Johns Hopkins University and Health Systems Archive - July 27, 2017 Category: Nursing Source Type: news

Associations between Greenness, Impervious Surface Area, and Nighttime Lights on Biomarkers of Vascular Aging in Chennai, India
Conclusion: Greenness, ISA, and NTL were associated with increased SBP, DBP, and cPP, and with reduced FMD, suggesting a possible additional EVA pathway for the relationship between urbanization and increased CVD prevalence in urban India. https://doi.org/10.1289/EHP541 Received: 20 May 2016 Revised: 03 January 2017 Accepted: 23 January 2017 Published: 02 August 2017 Address correspondence to K.J. Lane, Yale School of Forestry and Environmental Studies, 195 Prospect Street, New Haven, CT 06511 USA. Telephone: (781) 696-4537; Email: kevin.lane@yale.edu Supplemental Material is available online (https://doi.org/10.1289...
Source: EHP Research - August 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research