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Specialty: Neurology
Condition: Pain

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Total 1248 results found since Jan 2013.

Poor Health-related Quality of Life is Associated with Long-term Mortality in Young Adults with Cerebral Infarction
Background: Our aim was to investigate the effect of health-related quality of life (HRQOL) on subsequent mortality in young ischemic stroke patients in a population-based study.Methods: Young ischemic stroke patients were invited to a follow-up on average 6 years after their index stroke. HRQOL was measured by Short-Form 36 (SF-36) and the Nottingham Health Profile (NPH). Data on socioeconomic and functional states were obtained. Subsequent survival was obtained by examining the official population registry. Multivariate analyses were performed.Results: One hundred eighty-eight patients were included. The mean age on foll...
Source: Journal of Stroke and Cerebrovascular Diseases - August 9, 2012 Category: Neurology Authors: Halvor Naess, Harald Nyland Tags: Original Articles Source Type: research

Increase in Rate of Utilization of Withdrawal of Care in Acute Ischemic Stroke in USA (P1.209)
Conclusions:We found a considerable increase in rate of withdrawal of care with aggressive treatment, which may be due to disease severity and/or patient/family preference. Prognostic models and clinical experience for severe stroke patients may be biased by frequent withdrawal of care, leading to errors in prognostication with significant consequences including premature withdrawal of care, suboptimal outcomes and higher risk of short-term mortalityStudy Supported by: NADisclosure: Dr. Adil has nothing to disclose. Dr. Zweifler has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Adil, M., Zweifler, R. Tags: Pain and Palliative Care Source Type: research

Suprascapular nerve block for the treatment of hemiplegic shoulder pain in patients with long-term chronic stroke: a pilot study
AbstractHemiplegic shoulder pain is the most common pain condition after stroke. Suprascapular nerve block is an effective treatment for shoulder pain. The aim of this pilot study was to evaluate the effects of suprascapular nerve block on pain intensity, spasticity, shoulder passive range of motion, and quality of life in long-term chronic stroke patients with hemiplegic shoulder pain. Ten chronic stroke patients (over 2  years from onset) with hemiplegic shoulder pain graded ≥30 mm on the Visual Analogue Scale underwent suprascapular nerve block injection with 1 mL of 40 mg/mL methylprednisolone and 10 mL 0.5% bup...
Source: Neurological Sciences - July 11, 2017 Category: Neurology Source Type: research

Cerebral Hyperperfusion Syndrome After Carotid Revascularization and Acute Ischemic Stroke
AbstractPurpose of ReviewCerebral hyperperfusion syndrome (CHS) is a rare but significant complication after carotid revascularization and is increasingly recognized after acute stroke treatments. In this review, we discuss the epidemiology and pathophysiology of CHS, clinical presentation including ipsilateral headache, seizures, and focal neurological deficits, and radiographic presentation. We propose preventive therapies with emphasis on acute stroke post-thrombectomy hyperperfusion.Recent FindingsCHS was first described after carotid revascularization but is now also reported in patients with acute ischemic stroke. Pr...
Source: Current Pain and Headache Reports - March 19, 2018 Category: Neurology Source Type: research

Pain after stroke: A review.
Authors: Delpont B, Blanc C, Osseby GV, Hervieu-Bègue M, Giroud M, Béjot Y Abstract Pain after stroke (PAS) is a common clinical problem that is both underdiagnosed and undertreated. Yet, it induces depression and cognitive troubles, and impairs quality of life. To provide tools for practitioners, this report describes the most common PAS syndromes, including central post-stroke pain, spasticity and contractures, shoulder pain and complex regional pain syndromes, as well as headache and chondrocalcinosis, along with their risk factors, their prevention and their specific treatments. In addition, to ensure that th...
Source: Revue Neurologique - July 30, 2018 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research

Post-stroke pain caused by peripheral sensory hypersensitization after transient focal cerebral ischemia in rats.
Abstract The mechanisms underlying central post-stroke pain are not well understood and there is no satisfactory treatment. Here, in a rat model of stroke, we measured nociceptive threshold using current stimulation of primary afferent neurons in both hind paws. Male Wistar rats underwent middle cerebral artery occlusion (MCAO) for 50 min. Nociceptive thresholds for Aβ, Aδ and C fiber stimulation (at 2000, 250, and 5 Hz, respectively, using a Neurometer), and neurological deficits, were measured for 23 days after MCAO. Sensory thresholds in both hind paws were significantly lower in MCAO model rats than in contr...
Source: Brain Research - March 17, 2019 Category: Neurology Authors: Hyakkoku K, Umeda N, Shimada S, Imai T, Morioka Y, Sakaguchi G, Hara H Tags: Brain Res Source Type: research

Quantitative Assessment of Hand Spasticity After Stroke: Imaging Correlates and Impact on Motor Recovery
Conclusion: Severe hand spasticity early after stroke is negatively associated with hand motor recovery and positively associated with the development of secondary complications. Corticospinal tract damage predicts development of spasticity. Early quantitative hand spasticity measurement may have potential to predict motor recovery and could guide targeted rehabilitation interventions after stroke.
Source: Frontiers in Neurology - August 11, 2019 Category: Neurology Source Type: research

Brain activity changes in a monkey model of central post-stroke pain.
Abstract Central post-stroke pain (CPSP) can occur after stroke in the somatosensory pathway that includes the posterolateral region of the thalamus. Tactile allodynia, in which innocuous tactile stimuli are perceived as painful, is common in patients with CPSP. Previous brain imaging studies have reported plastic changes in brain activity in patients with tactile allodynia after stroke, but a causal relationship between such changes and the symptoms has not been established. We recently developed a non-human primate (macaque) model of CPSP based on thalamic lesions, in which the animals show behavioral changes co...
Source: Experimental Neurology - October 31, 2019 Category: Neurology Authors: Nagasaka K, Takashima I, Matsuda K, Higo N Tags: Exp Neurol Source Type: research

Patient Reported Outcomes Measurements Information System in Stroke Patients in Full and Shortened Format
Conclusion: PROMIS better reflects the overall health status of stroke patients beyond functional outcome as measured by the mRS. Simplification of the questionnaire with a single question per PROMIS domain could potentially replace the full questionnaire, but needs further validation.
Source: Frontiers in Neurology - January 22, 2021 Category: Neurology Source Type: research

Patient tolerability of suprascapular and median nerve blocks for the management of pain in post-stroke shoulder-hand syndrome
ConclusionsSuprascapular and median nerve blocks are safe and well-tolerated procedures for acute pain control in post-stroke SHS. Further studies should address the benefit of these procedures on overall pain reduction, functional recovery, and quality of life in SHS patients.
Source: Neurological Sciences - February 8, 2021 Category: Neurology Source Type: research

Acute prolonged motor aura resembling ischemic stroke after COVID − 19 vaccination (CoronaVac): the first case report
In this study, we present the first case of stroke mimic after CoronaVac vaccination. After negative imaging studies had been performed repeatedly, we reach a conclusion that stroke is unlikely to be the cause. Presumably, this phenomenon could possibly have abnormal functional imaging study. Therefore, we believed that it might be due to cortical spreading depression, like migraine aura, which we had conducted a literature review.
Source: The Journal of Headache and Pain - August 12, 2021 Category: Neurology Source Type: research

Activation of CREB-BDNF Pathway in Pyramidal Neurons in the Hippocampus Improves the Neurological Outcome of Mice with Ischemic Stroke
In this study, overexpression of CREB protein in pyramidal neurons in vCA1 by AAV virus significantly upregulated the content of BDNF and ameliorated the dysfunction induced by ischemic stroke. Our results demonstrated activation of the CREB-BDNF pathway in vCA1 pyramidal neurons significantly improved neurological deficits, pain perception, anxiety, and depression induced by ischemic stroke.
Source: Molecular Neurobiology - March 3, 2023 Category: Neurology Source Type: research

Effects of community ambulation training with 3D-printed ankle –foot orthosis on gait and functional improvements: a case series of three stroke survivors
IntroductionMany of the patients using ankle–foot orthoses (AFOs) experience poor fit, pain, discomfort, dislike of the aesthetics of the device, and excessive range of motion restrictions, which diminish the use of AFOs. Although 3D-printed ankle–foot orthoses (3D-AFOs) affect patient satisfaction and overall gait functions such as ankle moment, joint range of motion (ROM), and temporal-spatial parameters, the material properties and manufacturing process of 3D-AFOs are still diverse; the clinical effects of community ambulation using 3D-AFOs and satisfaction in patients with stroke are poorly understood.Case descript...
Source: Frontiers in Neurology - May 31, 2023 Category: Neurology Source Type: research

Pilot assessment of a comfort scale in stroke patients
Conclusions: The scale can help to define difficulties in daily living situations and identify opportunities for intervention in stroke patients.
Source: Journal of the Neurological Sciences - February 18, 2014 Category: Neurology Authors: Caroline Rogeau, Franck Beaucamp, Etienne Allart, Walter Daveluy, Marc Rousseaux Tags: Original Articles Source Type: research

Recurrent Intra-Luminal Aortic Thrombus And Ischemic Stroke In A Patient With Essential Thrombocythemia (P6.262)
CONCLUSIONS: This case highlights the importance of recognizing essential thrombocythemia as an entity that can lead to devastating complications, including acute coronary syndrome and either arterial and venous thrombosis. Early recognition and effective cytoreductive therapy are cornerstones to the prevention of recurrent embolism. This case demonstrates that Intra-luminal thrombus may resolve and reappear, and can vary greatly in its clinical consequences.Disclosure: Dr. Vela-Duarte has nothing to disclose. Dr. Flaster has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Vela-Duarte, D., Flaster, M. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research