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Specialty: Endocrinology
Condition: Hypertension

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Total 255 results found since Jan 2013.

Association of Glucagon ‐like Peptide‐1 Receptor Agonist (GLP‐1 RA) Use and Rates of Acute Myocardial Infarction, Stroke, and Overall Mortality in Patients with Type 2 Diabetes Mellitus in a Large Integrated Health System
ConclusionsGLP‐1 RA exposure was found to be associated with a reduction in the risk of cardiovascular events observed and overall mortality among patients with T2D with and without established CVD, after adjusting for potential confounders.
Source: Diabetes, Obesity and Metabolism - April 13, 2017 Category: Endocrinology Authors: Robert S. Zimmerman, Todd M. Hobbs, Brian J. Wells, Sheldon X. Kong, Michael W. Kattan, Jon Bouchard, Kevin M. Chagin, Changhong Yu, Brian Sakurada, Alex Milinovich, Wayne Weng, Janine M. Bauman, Kevin M. Pantalone Tags: ORIGINAL ARTICLE Source Type: research

Prevalence of hypertension and prehypertension in adolescence in Ahvaz, Iran
Conclusions The prevalence of high blood pressure was found to be lower than other studies in our country. The prevalence of the high blood pressure in boys was significantly higher than girls. This study, like other studies showed high correlation between being overweight and an increase in systolic and diastolic blood pressure.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 10, 2017 Category: Endocrinology Source Type: research

Stroke disclosing primary aldosteronism: Report on three cases and review of the literature.
CONCLUSION: Although cerebrovascular events are quite common in PA, their occurrence as initial feature can be misleading. The association of hypokaliemia and refractory hypertension in ischemic or hemorrhagic strokes should prompt an assessment of the RAAS to rule out PA and initiate adequate management as soon as possible in order to avoid further complications. PMID: 28168953 [PubMed - as supplied by publisher]
Source: Annales d'Endocrinologie - February 2, 2017 Category: Endocrinology Authors: Nasri A, Mansour M, Brahem Z, Kacem A, Hassan AA, Derbali H, Messelmani M, Zaouali J, Mrissa R Tags: Ann Endocrinol (Paris) Source Type: research

Baseline Adiponectin Concentration and Clinical Outcomes among Patients with Diabetes and Recent Acute Coronary Syndrome in the EXAMINE Trial
ConclusionsIn this contemporary population of patients with diabetes and ACS, adiponectin concentration was independently associated with increased risk of CV death, all‐cause mortality, and HF hospitalization. The relationship between adiponectin and CV outcomes is complex and deserves further study.
Source: Diabetes, Obesity and Metabolism - January 31, 2017 Category: Endocrinology Authors: Brian A. Bergmark, Christopher P. Cannon, William B. White, Petr Jarolim, Yuyin Liu, Marc P. Bonaca, Faiez Zannad, David A. Morrow Tags: ORIGINAL ARTICLE Source Type: research

Salt and hypertension in diabetes
AbstractWorldwide, the number of patients with diabetes is increasing. Adults with diabetes have a two- to threefold increased risk of heart attack and stroke, and diabetic nephropathy is a leading cause of end-stage renal failure. Salt sensitivity of blood pressure is reported to be elevated in patients with diabetes. Hyperinsulinemia, hyperglycemia, and an activated sympathetic nervous system play key roles in the genesis of salt-sensitive blood pressure in individuals who are obese and/or have type 2 diabetes. In this review, I summarize previous research performed to improve our understanding of the relationship betwee...
Source: Diabetology International - January 27, 2017 Category: Endocrinology Source Type: research

Long-term risk of stroke in type 2 diabetes patients with diabetic ketoacidosis: A population-based, propensity score-matched, longitudinal follow-up study.
CONCLUSION: T2D patients with previous DKA have a higher risk of stroke, especially ischaemic strokes. PMID: 28129999 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism - January 23, 2017 Category: Endocrinology Authors: Chen YL, Weng SF, Yang CY, Wang JJ, Tien KJ Tags: Diabetes Metab Source Type: research

Hormonal Contraception and Risk of Thromboembolism in Women With Diabetes
CONCLUSIONS The absolute risk of thromboembolism among women with type 1 or 2 diabetes using hormonal contraception is low. Highly effective, intrauterine and subdermal contraceptives are excellent options for women with diabetes who hope to avoid the teratogenic effects of hyperglycemia by carefully planning their pregnancies.
Source: Diabetes Care - January 19, 2017 Category: Endocrinology Authors: OBrien, S. H.; Koch, T.; Vesely, S. K.; Schwarz, E. B. Tags: Epidemiology/Health Services Research Source Type: research

Influence of vitamin D levels on the treatment of premature ventricular complexes in patients with chronic kidney disease
Conclusions We suggest that the effectiveness of β-blocker treatment for PVCs in CKD patients was observed in all 25(OH)D levels. However, the responsiveness was higher in patients with a normal range of 25(OH)D in comparison to patients with deficiency or insufficiency in 25(OH)D levels. Whether vitamin D supplementation increases the efficacy of beta-blocker mediated suppression of PVCs requires further evaluation.
Source: IJC Metabolic and Endocrine - January 6, 2017 Category: Endocrinology Source Type: research

Very low-density lipoprotein (VLDL)-induced signals mediating aldosterone production
Aldosterone, secreted by the adrenal zona glomerulosa, enhances sodium retention, thus increasing blood volume and pressure. Excessive production of aldosterone results in high blood pressure and contributes to cardiovascular and renal disease, stroke and visual loss. Hypertension is also associated with obesity, which is correlated with other serious health risks as well. Although weight gain is associated with increased blood pressure, the mechanism by which excess fat deposits increase blood pressure remains unclear. Several studies have suggested that aldosterone levels are elevated with obesity and may represent a lin...
Source: Journal of Endocrinology - January 3, 2017 Category: Endocrinology Authors: Tsai, Y.-Y., Rainey, W. E., Bollag, W. B. Tags: Review Source Type: research

Association between Carotid Intima ‐Media Thickness and Fasting Blood Glucose level: A Population‐Based Cross‐Sectional Study among Low‐Income Adults in Rural China
ConclusionsThese findings suggest that it is crucial to manage and control traditional risk factors in low‐income populations in China in order to decelerate the recent dramatic increase in stroke incidence and to reduce the burden of stroke.This article is protected by copyright. All rights reserved.
Source: Journal of Diabetes Investigation - December 31, 2016 Category: Endocrinology Authors: Liu Gao, Lingling Bai, Min Shi, Jingxian Ni, Hongyan Lu, Yanan Wu, Jun Tu, Xianjia Ning, Jinghua Wang, Yukun Li Tags: Original Article Source Type: research

The relationship between dietary intake and other cardiovascular risk factors with blood pressure in individuals without a history of a cardiovascular event: Evidence based study with 5670 subjects
Conclusion In our representative population from North-Eastern Iran, it appears that in adults without a history of cardiovascular disease, crude or energy adjusted intake of phosphorus and total fatty acid intake were significant determinants of BP, however we found no association between sodium and potassium intake with BP.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - December 9, 2016 Category: Endocrinology Source Type: research

Interleukin-18 gene polymorphism and risk of CVD in older patients with type 2 diabetes mellitus
Diabetes mellitus (DM) is a chronic multifactorial disease characterized by persistent hyperglycemia, that is associated with increased morbidity and mortality. The prevalence of type 2 diabetes (T2DM) is high among the elderly population. In United States, the prevalence of diabetes increased by 62% from 1994 to 2003 among persons over 65 years old [1]. Metabolic changes that are risk factors for T2DM are associated with cardiovascular diseases, mainly coronary artery disease, atherosclerosis, hypertension and stroke [2].
Source: Diabetes Research and Clinical Practice - September 29, 2016 Category: Endocrinology Authors: Monika Buraczynska, Katarzyna Ksiazek, Pawel Zukowski, Agnieszka Grzebalska Source Type: research

Aldosterone producing adenoma with a somatic KCNJ5 mutation revealing APC dependent Familial Adenomatous Polyposis.
CONCLUSIONS: This case report underlines the need of establishing the frequency of germline APC variants in patients with primary aldosteronism and bilateral macronodular adrenal hyperplasia, as their presence may predispose to APA development and severe hypertension well before the first FAP symptoms appear. From a mechanistic point of view, it supports a two-hit model for APA development, whereby the first hit drives increased cell proliferation while the second hit specifies the pattern of hormonal secretion. PMID: 27648962 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - September 19, 2016 Category: Endocrinology Authors: Vouillarmet J, Fernandes-Rosa F, Graeppi-Dulac J, Lantelme P, Decaussin-Petrucci M, Thivolet C, Peix JL, Boulkroun S, Clauser E, Zennaro MC Tags: J Clin Endocrinol Metab Source Type: research

Burden and risk factors of dyslipidemia-results from a STEPS survey in Punjab India
Conclusions The study reported high prevalence of dyslipidemia, calling for an urgent attention.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - August 23, 2016 Category: Endocrinology Source Type: research

Rosuvastatin decreases testosterone levels but not sexual function in men with type 2 diabetes
Type 2 diabetes is often associated with hypertension and dyslipidemia. Because dyslipidemia exacerbates macrovascular disease, including coronary heart disease, stroke, and peripheral vascular disease, lipid lowering therapy is indicated for patients with type 2 diabetes, because lipid lowering therapy has been found to greatly reduce cardiovascular events in this population [1]. Statin use, however, can lead to reduced hepatic synthesis of cholesterol by inhibiting 3-hydroxy-methylglutaryl-CoA reductase.
Source: Diabetes Research and Clinical Practice - August 5, 2016 Category: Endocrinology Authors: Ching Jung Hsieh, Bin Huang Source Type: research