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Condition: Hypertension
Nutrition: Calcium

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Total 337 results found since Jan 2013.

Obstructive sleep apnea is independently associated with subclinical coronary atherosclerosis among middle-aged women
Conclusion Moderate to severe OSA is independently associated with the presence of CAC in middle-aged women. These results reinforce the concept that women are also susceptible to the cardiovascular consequences of OSA.
Source: Sleep and Breathing - July 5, 2016 Category: Respiratory Medicine Source Type: research

New perspectives on dairy and cardiovascular health
This month's Paper of the Month is from Proceedings of the Nutrition Society and is entitled ‘Milk and dairy produce and CVD: new perspectives on dairy and cardiovascular health'. Authors, Julie A. Lovegrove and Ditte A. Hobbs, University of Reading, discuss the evidence on dairy product intake and cardiovascular disease risk and implications for dietary advice. One key recommendation for decreasing cardiovascular disease (CVD) risk is to reduce saturated fat intake to less than 10% total energy, yet the majority of the UK population are exceeding this level. As dairy products contribute over 27% of total dietary saturat...
Source: The Nutrition Society - July 8, 2016 Category: Nutrition Authors: Cassandra Ellis Source Type: news

Obstructive sleep apnea is independently associated with subclinical coronary atherosclerosis among middle-aged women.
CONCLUSION: Moderate to severe OSA is independently associated with the presence of CAC in middle-aged women. These results reinforce the concept that women are also susceptible to the cardiovascular consequences of OSA. PMID: 27384043 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - July 5, 2016 Category: Sleep Medicine Authors: Medeiros AK, Coutinho RQ, Barros IM, Costa LO, Leite AP, Bittencourt MS, Lustosa TC, Carvalho MM, Lira MP, Ferreira MN, Lorenzi-Filho G, Drager LF, Pedrosa RP Tags: Sleep Breath Source Type: research

Renin ‐Angiotensin System Inhibitors vs Other Antihypertensives in Hypertensive Blacks: A Meta‐Analysis
The purpose of this study was to assess the effects of renin‐angiotensin system (RAS) inhibitors vs other antihypertensive agents on cardiovascular outcomes in hypertensive black patients. The authors performed a systematic review and meta‐analysis of studies that compared the effects of angiotensin‐converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) with calcium channel blockers (CCBs), diuretics, and β‐blockers in hypertensive black patients on cardiovascular outcomes. A total of 38,983 patients with a mean age of 60 years and mean follow‐up of 4 years were included in our meta‐analy...
Source: The Journal of Clinical Hypertension - July 3, 2016 Category: Cardiology Authors: Mohan Palla, Tomo Ando, Emmanuel Androulakis, Tesfaye Telila, Alexandros Briasoulis Tags: Original Paper Source Type: research

Low Dose Combination Antihypertensive Pharmacotherapy Can Be Very Effective. Angiotensin Receptor Blockers/Angiotensin Converting Enzyme Inhibitors Are Often Unnecessary
Introduction: Hypertension treatment often fails to achieve good blood pressure (BP) control, despite a wide range of available pharmacotherapy, partly because of poor side effect issues, which are often dose-related. Angiotensin receptor blockers, ARBs and angiotensin converting enzyme inhibitors, ACE-Is are known to increase BP variability, which may predispose to falls and stroke, compared to diuretics and calcium channel blockers (CCBs), which reduce BP variability.
Source: Heart, Lung and Circulation - July 26, 2016 Category: Cardiology Authors: S. Dimmitt, A. Moran, M. Scartozzi, H. Stampfer Tags: 36 Source Type: research

Pattern of antihypertensive therapy among diabetic hyperten- sive patients in zewditu memorial hospital, addis ababa.
CONCLUSION: The pattern of antihypertensive drug therapy in our patients was consistent with the current treatment guidelines. However, the majority of diabetic-hypertensive patients did not reach target blood pressure. PMID: 27476227 [PubMed - in process]
Source: Ethiopian Medical Journal - August 3, 2016 Category: African Health Tags: Ethiop Med J Source Type: research

Does Deficiency of Vitamin D Increase New Onset Atrial Fibrillation after Coronary Artery Bypass Grafting Surgery?
CONCLUSION: This study has shown that deficiency of vitamin D is associated with new onset AF post-CABG surgery. PMID: 27585197 [PubMed - as supplied by publisher]
Source: The Heart Surgery Forum - September 2, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Emren SV, Aldemir M, Ada F Tags: Heart Surg Forum Source Type: research

Association Between Calcium Level and Hematoma Size and Expansion
Intracerebral hemorrhage (ICH) is a common and deadly type of stroke, with high rates of morbidity and mortality (40%-50% in most series). There are several well-described and validated risk factors and diseases that increase the risk of ICH, including race, hypertension, use of anticoagulants, amyloid angiopathy, renal insufficiency, thrombolytic therapy, and drug abuse. However, not all ICHs are associated with one of these risk factors. This suggests that there might be some other modifying factors involved.
Source: JAMA Neurology - September 6, 2016 Category: Neurology Source Type: research

Reversible cerebral vasoconstriction syndrome: A rare pediatric cause of thunderclap headaches.
We report on a case of a 13-year-old boy presenting with acute severe headaches, triggered by physical exertion. His past medical history was uneventful. Moderate headache persisted between exacerbations for 4 weeks. He secondarily presented with signs of intracranial hypertension. Brain magnetic resonance angiography (MRA) revealed multifocal narrowing of the cerebral arteries. A glucocorticoid treatment was started based on the hypothesis of primary angiitis of the CNS. The symptoms rapidly improved, and repeat angiography at 3 months showed no vasoconstriction. Although pediatric cases are rare, RCVS should be considere...
Source: Archives de Pediatrie - September 13, 2016 Category: Pediatrics Authors: Trolliet M, Sevely A, Albucher JF, Nasr N, Hachon Lecamus C, Deiva K, Cheuret E Tags: Arch Pediatr Source Type: research

Genetic basis of Atrial Fibrillation
Publication date: Available online 24 September 2016 Source:Genes & Diseases Author(s): Oscar Campuzano, Alexandra Perez-Serra, Anna Iglesias, Ramon Brugada Atrial fibrillation is the most common sustained arrhythmia and remains as one of main challenges in current clinical practice. The disease may be induced secondary to other diseases such as hypertension, valvular heart disease, and heart failure, conferring an increased risk of stroke and sudden death. Epidemiological studies have provided evidence that genetic factors play an important role and up to 30% of clinically diagnosed patients may have a family his...
Source: Genes and Diseases - September 24, 2016 Category: Genetics & Stem Cells Source Type: research

Hyperaldosteronism induces left atrial systolic and diastolic dysfunction
Patients with hypertension and hyperaldosteronism show an increased risk of stroke compared with patients with essential hypertension. Aim of the study was to assess the effects of aldosterone on left atrial function in rats as a potential contributor to thromboembolism. Osmotic mini-pumps delivering 1.5 μg aldosterone/h were implanted in rats subcutaneously (Aldo, n = 39; controls, n = 38). After 8 wk, left ventricular pressure-volume analysis of isolated working hearts was performed, and left atrial systolic and diastolic function was also assessed by atrial pressure-diameter loops. Moreover, left atrial myocytes were...
Source: AJP: Heart and Circulatory Physiology - September 30, 2016 Category: Cardiology Authors: Reil, J.-C., Tauchnitz, M., Tian, Q., Hohl, M., Linz, D., Oberhofer, M., Kaestner, L., Reil, G.-H., Thiele, H., Steendijk, P., Böhm, M., Neuberger, H.-R., Lipp, P. Tags: Integrative Cardiovascular Physiology and Pathophysiology Source Type: research

Association of Subjective and Objective Sleep Duration as well as Sleep Quality with Non-Invasive Markers of Sub-Clinical Cardiovascular Disease (CVD): A Systematic Review.
CONCLUSIONS: Overall, our review provided mixed results, which is generally in line with published literature, with most of the studies showing a significant relationship with subclinical CVD, but only some studies failed to demonstrate such an association. Although such mechanistic relationship needs further evaluation in order to determine appropriate screening strategies in vulnerable populations, this review strongly suggested the existence of a relationship between abnormal sleep duration and quality with increased subclinical CVD burden. PMID: 27840384 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - November 16, 2016 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Hypertensive Crisis: pharmacotherapy and complications.
Authors: Wani-Parekh P, Garcia-Blanco C, Mendez M, Mukherjee D Abstract Cardiovascular diseases (CVD) are the number one cause of death globally compared to any other cause. CVD accounts for approximately 17.3 million deaths per year and are rising. Hypertension is the leading risk factor for cardiovascular diseases. Approximately 80 million people suffer from hypertension in the U.S. While, majority of these individuals are on antihypertensive medications only 54% of individuals with hypertension are optimally controlled. Heart failure and stroke are some of the devastating complications of uncontrolled hypertensi...
Source: Cardiovascular and Hematological Disorders Drug Targets - December 23, 2016 Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research

Very low-density lipoprotein (VLDL)-induced signals mediating aldosterone production
Aldosterone, secreted by the adrenal zona glomerulosa, enhances sodium retention, thus increasing blood volume and pressure. Excessive production of aldosterone results in high blood pressure and contributes to cardiovascular and renal disease, stroke and visual loss. Hypertension is also associated with obesity, which is correlated with other serious health risks as well. Although weight gain is associated with increased blood pressure, the mechanism by which excess fat deposits increase blood pressure remains unclear. Several studies have suggested that aldosterone levels are elevated with obesity and may represent a lin...
Source: Journal of Endocrinology - January 3, 2017 Category: Endocrinology Authors: Tsai, Y.-Y., Rainey, W. E., Bollag, W. B. Tags: Review Source Type: research