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MRI for all: Cheap portable scanners aim to revolutionize medical imaging
.news-article__hero--featured .parallax__element{ object-position: 47% 50%; -o-object-position: 47% 50%; } The patient, a man in his 70s with a shock of silver hair, lies in the neuro intensive care unit (neuro ICU) at Yale New Haven Hospital. Looking at him, you’d never know that a few days earlier a tumor was removed from his pituitary gland. The operation didn’t leave a mark because, as is standard, surgeons reached the tumor through his nose. He chats cheerfully with a pair of research associates who have come to check his progress with a new and potentially revolutionary device they are testing. The cylind...
Source: Science of Aging Knowledge Environment - February 23, 2023 Category: Geriatrics Source Type: research

Second death linked to potential antibody treatment for Alzheimer ’s disease
A 65-year-old woman who was receiving a promising experimental treatment to slow the cognitive decline caused by her early Alzheimer’s disease recently died from a massive brain hemorrhage that some researchers link to the drug. The clinical trial death, described in an unpublished case report Science has obtained, is the second thought to be associated with the antibody called lecanemab. The newly disclosed fatality intensifies questions about its safety and how widely lecanemab should be prescribed if ultimately approved by regulators. The woman, who received infusions of the antibody as part of the trial, s...
Source: ScienceNOW - November 28, 2022 Category: Science Source Type: news

Machine learning prediction of symptomatic intracerebral hemorrhage after stroke thrombolysis: a cross-cultural validation in Caucasian and Han Chinese cohort
CONCLUSION: The established SVM model is feasible for predicting the risk of sICH after thrombolysis quickly and efficiently in both Caucasian and Han Chinese cohort.PMID:36225969 | PMC:PMC9549180 | DOI:10.1177/17562864221129380
Source: Adv Data - October 13, 2022 Category: Epidemiology Authors: Junfeng Liu Xinyue Chen Xiaonan Guo Renjie Xu Yanan Wang Ming Liu Source Type: research

Unsupervised Deep Learning for Stroke Lesion Segmentation on Follow-up CT Based on Generative Adversarial Networks FUNCTIONAL
CONCLUSIONS: An unsupervised generative adversarial network can be used to obtain automated infarct lesion segmentations with a moderate Dice similarity coefficient and good volumetric correspondence.
Source: American Journal of Neuroradiology - August 8, 2022 Category: Radiology Authors: van Voorst, H., Konduri, P. R., van Poppel, L. M., van der Steen, W., van der Sluijs, P. M., Slot, E. M. H., Emmer, B. J., van Zwam, W. H., Roos, Y. B. W. E. M., Majoie, C. B. L. M., Zaharchuk, G., Caan, M. W. A., Marquering, H. A., on behalf of the CONTR Tags: FUNCTIONAL Source Type: research

CT-based radiomics for differentiating intracranial contrast extravasation from intraparenchymal haemorrhage after mechanical thrombectomy
ConclusionsThe radiomic signature constructed based on initial post-operative nonenhanced CT after mechanical thrombectomy can effectively differentiate IPH from iodinated contrast extravasation.Key Points•Radiomic features were extracted from intraparenchymal areas of hyperattenuation on initial post-operative CT scans after mechanical thrombectomy.•The nonenhanced CT-based radiomic signature can differentiate IPH from iodinated contrast extravasation early.•The radiomic signature may help prevent unnecessary rescanning after mechanical thrombectomy, especially in cases where contrast extravasation is highly suggestive.
Source: European Radiology - February 3, 2022 Category: Radiology Source Type: research

A Clinical-Radiomics Nomogram for Functional Outcome Predictions in Ischemic Stroke
ConclusionThis novel noninvasive clinical-radiomics nomogram shows good performance in predicting ischemic stroke prognosis.
Source: Neurology and Therapy - June 25, 2021 Category: Neurology Source Type: research

Is This Contrast? Is This Blood? An Agreement Study on Post-thrombectomy Computed Tomography Scans
Conclusion: Physician judgment for the presence of blood and/or contrast on day-1 post-thrombectomy non-contrast CT scan shows limited inter-observer reliability. Advanced imaging modalities may then be warranted for challenging clinical cases.
Source: Frontiers in Neurology - December 22, 2020 Category: Neurology Source Type: research

3D Deep Neural Network Segmentation of Intracerebral Hemorrhage: Development and Validation for Clinical Trials
AbstractIntracranial hemorrhage (ICH) occurs when a blood vessel ruptures in the brain. This leads to significant morbidity and mortality, the likelihood of which is predicated on the size of the bleeding event. X-ray computed tomography (CT) scans allow clinicians and researchers to qualitatively and quantitatively diagnose hemorrhagic stroke, guide interventions and determine inclusion criteria of patients in clinical trials. There is no currently available open source, validated tool to quickly segment hemorrhage. Using an automated pipeline and 2D and 3D deep neural networks, we show that we can quickly and accurately ...
Source: Neuroinformatics - September 26, 2020 Category: Neuroscience Source Type: research

A multi-path 2.5 dimensional convolutional neural network system for segmenting stroke lesions in brain MRI images
Publication date: Available online 9 December 2019Source: NeuroImage: ClinicalAuthor(s): Yunzhe Xue, Fadi G. Farhat, Olga Boukrina, A.M. Barrett, Jeffrey R. Binder, Usman W. Roshan, William W. GravesAbstractAutomatic identification of brain lesions from magnetic resonance imaging (MRI) scans of stroke survivors would be a useful aid in patient diagnosis and treatment planning. It would also greatly facilitate the study of brain-behavior relationships by eliminating the laborious step of having a human expert manually segment the lesion on each brain scan. We propose a multi-modal multi-path convolutional neural network sys...
Source: NeuroImage: Clinical - December 11, 2019 Category: Radiology Source Type: research

Samsung ’ s NeuroLogica, MaxQ AI ink collab distro deal
Samsung Electronics (LON:BC94) subsidiary NeuroLogica said today that it inked a distribution deal with MaxQ AI to integrate its artificial intelligence software with NeuroLogica’s medical imaging tech in the U.S. and EU’s acute care marketplace. Through the deal, NeuroLogica said that it will offer MaxQ’s Accipio IX, part of the AI-company’s FDA-cleared and CE Mark approved Accipio Insight intracranial hemorrhage platform intended to support acute care physicians by identifying patients with suspected intracranial hemorrhage using non-contrast head computed tomography imaging. “We are honore...
Source: Mass Device - November 20, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Distribution Imaging Neurological Software / IT maxqai NeuroLogica Corp. samsung Source Type: news

Letter to the Editor: Pneumocephalus: Is the needle size significant?
Discussion. Pneumocephalus is defined by two mechanisms: a ball-valve and an inverted bottle concept.1 The ball-valve type implies positive pressure events, such as coughing or valsalva maneuvers, that prevent air escape. Tension pneumocephalus is included in this mechanism, causing a parenchymal mass effect. The inverted bottle theory includes a negative intracranial pressure gradient following cerebrospinal fluid drainage, relieved by air influx. A small pneumocephalus is usually sealed by blood clots or granulation, allowing spontaneous reabsorption and resolution.[1] Otherwise, the lateral positioning of a patient duri...
Source: Innovations in Clinical Neuroscience - February 1, 2018 Category: Neuroscience Authors: ICN Online Editor Tags: Assessment Tools CNS Infections Current Issue Letters to the Editor Neurologic Systems and Symptoms Neurology Stroke Traumatic Brain Injury epidural needle size Pneumocephalus spinal tap Source Type: research

Impact of Asynchronous Training on Radiology Learning Curve among Emergency Medicine Residents and Clerkship Students.
CONCLUSION: Incorporating asynchronous WBL modules into EM clerkship and residency curriculum provides early radiographic exposure in their clinical training and can enhance diagnostic head CT scan interpretation. PMID: 29272248 [PubMed - in process]
Source: The Permanente journal - December 24, 2017 Category: General Medicine Tags: Perm J Source Type: research

Effect of subtypes of neglect on functional outcome in stroke patients
Conclusions Our data confirm the negative prognostic effect of neglect on functional outcome in a large sample. We also show the importance of evaluating and training according to neglect subtype to improve functional independence.
Source: Annals of Physical and Rehabilitation Medicine - September 22, 2017 Category: Rehabilitation Source Type: research

DIS-17-0023 The Enduring Health Challenges of Afghan Immigrants and Refugees in Iran: A Systematic Review
This article does not contain any studies with human participants or animals performed by the author. Data Availability All national (MagIran, Science Information Database (SID) and Iranmedex) and international (PubMed, Scopus) databases were searched from November 2010 to November 2016 using keywords both in English and Persian: Afghan immigrants, Afghan refugees, Iran, infectious diseases, tuberculosis, HIV, Hepatitis B and C, non-communicable disease, food security, mental health, barriers, health insurance, access to health service. All related websites and webpages were also searched by Google with the same keywords ...
Source: PLOS Currents Disasters - July 21, 2017 Category: International Medicine & Public Health Authors: nasim Source Type: research

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