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Condition: Ischemic Stroke
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Total 575 results found since Jan 2013.

Teleneurocritical Care for Patients with Large Vessel Occlusive Ischemic Stroke Treated by Thrombectomy
ConclusionsTeleneurocritical care allows for equivalent favorable functional outcomes compared with in-person neurocritical care for patients with acute large vessel ischemic stroke receiving thrombectomy. The standardized protocols used by TNCC in this study, specifically the comprehensive 24/7 treatment of patients in the intensive care unit for the length of their stay, may be relevant for other health systems with limited in-person resources; however, additional study is required.
Source: Neurocritical Care - November 2, 2022 Category: Neurology Source Type: research

Stroke
This article wil l explore the nursing care of the patient with ischemic and hemorrhagic stroke during the first 24 hours.
Source: Nursing Clinics of North America - June 8, 2023 Category: Nursing Authors: Susan E. Wilson, Susan Ashcraft Source Type: research

Rates and reasons for hospital readmission after acute ischemic stroke in a US population-based cohort
We examined readmissions rates, diagnoses at readmission, and risk factors associated with readmission following acute ischemic stroke (AIS) in a large United States (US) administrative database. Using the 201 9 Nationwide Readmissions Database, we identified adults discharged with AIS (ICD-10-CM I63*) as the principal diagnosis. Survival analysis with Weibull accelerated failure time regression was used to examine variables associated with hospital readmission. In 2019, 273,811 of 285,451 AIS patients su rvived their initial hospitalization. Of these, 60,831 (22.2%) were readmitted within 2019. Based on Kaplan Meyer analy...
Source: PLoS One - August 3, 2023 Category: Biomedical Science Authors: Lily W. Zhou Source Type: research

Comprehensive Cardiac Rehabilitation for Secondary Prevention After Transient Ischemic Attack or Mild Stroke: PSYCHOLOGICAL PROFILE AND OUTCOMES.
CONCLUSIONS: Anxiety and executive dysfunction persisted post-TIA/MNDS. Although promising for secondary prevention post-TIA/MNDS, CCR was not independently associated with psychological improvements. CCR psychological treatment may benefit depression. Subacute NYHA class and depression may later affect quality of life. PMID: 28727668 [PubMed - as supplied by publisher]
Source: Journal of Cardiopulmonary Rehabilitation and Prevention - July 19, 2017 Category: Rehabilitation Authors: Prior PL, Hachinski V, Chan R, Unsworth K, Mytka S, Harnadek M, OʼCallaghan C, Suskin N Tags: J Cardiopulm Rehabil Prev Source Type: research

Clinical and Angiographic Outcomes with the Combined Local Aspiration and Retriever in the North American Solitaire Stent-Retriever Acute Stroke (NASA) Registry
Background: Various techniques are used to enhance the results of mechanical thrombectomy with stent-retrievers, including proximal arrest with balloon guide catheter (BGC), conventional large bore proximal catheter (CGC), or in combination with local aspiration through a large-bore catheter positioned at the clot interface (Aspiration-Retriever Technique for Stroke [ARTS]). We evaluated the impact of ARTS in the North American Solitaire Acute Stroke (NASA) registry.Summary: Data on the use of the aspiration technique were available for 285 anterior circulation patients, of which 29 underwent ARTS technique, 131 CGC, and 1...
Source: Interventional Neurology - October 10, 2017 Category: Neurology Source Type: research

Comparative Outcomes of Mechanical Thrombectomy for Acute Ischemic Stroke in Patients  with and without Atrial Fibrillation
Stroke is a leading cause of disability and death in the United States (1). Cardioembolic strokes account for approximately 1 in 5 ischemic strokes, with atrial fibrillation (AF) being the most common cause of cardioembolic stroke (2). Acute ischemic strokes in patients with AF are associated with a higher degree of disability and worse outcomes than in patients without AF (3). Because of its proven efficacy, mechanical thrombectomy (MT) with second-generation stent retrievers has been recently assigned a class IA recommendation for the treatment of ischemic stroke in select group of patients (4).
Source: Journal of Vascular and Interventional Radiology : JVIR - October 20, 2017 Category: Radiology Authors: Muhammad Bilal Munir, Fahad Alqahtani, Abdelrahman Beltagy, Abdul Tarabishy, Mohamad Alkhouli Tags: Letter to the Editor Source Type: research

Clinical and Angiographic Outcomes with the Combined Local Aspiration and Retriever in the North American Solitaire Stent-Retriever Acute Stroke (NASA) Registry
Background: Various techniques are used to enhance the results of mechanical thrombectomy with stent-retrievers, including proximal arrest with balloon guide catheter (BGC), conventional large bore proximal catheter (CGC), or in combination with local aspiration through a large-bore catheter positioned at the clot interface (Aspiration-Retriever Technique for Stroke [ARTS]). We evaluated the impact of ARTS in the North American Solitaire Acute Stroke (NASA) registry.Summary: Data on the use of the aspiration technique were available for 285 anterior circulation patients, of which 29 underwent ARTS technique, 131 CGC, and 1...
Source: Interventional Neurology - October 25, 2017 Category: Neurology Source Type: research

Atrial Septal Defect and the Risk of Ischemic Stroke in the Perioperative Period of Noncardiac Surgery
Stroke is a serious complication of non-cardiac surgery. Congenital defects of the interatrial septum may be a potent risk factor for perioperative stroke. The aim of the present study was to determine the association between atrial septal defect (ASD) or patent foramen ovale (PFO) and in-hospital perioperative ischemic stroke after non-cardiac surgery in a large nationwide cohort of patients hospitalized in the United States. Patients undergoing noncardiac surgery between 2004 and 2014 were identified using the Healthcare Cost and Utilization Project's National Inpatient Sample.
Source: The American Journal of Cardiology - July 14, 2019 Category: Cardiology Authors: Nathaniel R. Smilowitz, Varun Subashchandran, Jeffrey S. Berger Source Type: research

Causes of Acute Stroke
This article reviews the imaging patterns of acute strokes, and how the infarct pattern and imaging characteristics can suggest an underlying cause.
Source: Radiologic Clinics of North America - October 1, 2019 Category: Radiology Authors: Ashley Knight-Greenfield, Joel Jose Quitlong Nario, Ajay Gupta Source Type: research

Endovascular Treatment Decision Making in Patients with Low Baseline ASPECTS: Insights from UNMASK EVT, an International Multidisciplinary Study
Endovascular therapy is a highly effective treatment for acute ischemic stroke (AIS) due to large vessel occlusion (LVO)1 and now considered standard of care.2 In most randomized EVT trials, patients with low Alberta Stroke Program Early CT Score (ASPECTS) scores were either excluded or underrepresented. Hence, current European and North American guidelines for the early management of patients with acute ischemic stroke restrict level 1A recommendations for endovascular therapy (EVT) to patients with baseline ASPECTS score>5.
Source: Journal of Stroke and Cerebrovascular Diseases - October 29, 2020 Category: Neurology Authors: Johanna Maria Ospel, Ravinder Singh, Nima Kashani, Mohammed Almekhlafi, Alexis Wilson, Urs Fischer, Bruce Campbell, Shinichi Yoshimura, Francis Turjman, Pillai Sylaja, Ji-Hoe Heo, Michael D. Hill, Gustavo Saposnik, Mayank Goyal, Bijoy Menon Source Type: research

Blood-Brain Barrier Damage in Ischemic Stroke and Its Regulation by Endothelial Mechanotransduction
Ischemic stroke, a major cause of mortality in the United States, often contributes to disruption of the blood-brain barrier (BBB). The BBB along with its supportive cells, collectively referred to as the “neurovascular unit,” is the brain’s multicellular microvasculature that bi-directionally regulates the transport of blood, ions, oxygen, and cells from the circulation into the brain. It is thus vital for the maintenance of central nervous system homeostasis. BBB disruption, which is associated with the altered expression of tight junction proteins and BBB transporters, is believed to exacerbate brain injury caused...
Source: Frontiers in Physiology - December 22, 2020 Category: Physiology Source Type: research

Tenecteplase for Acute Ischemic Stroke Treatment
Semin Neurol DOI: 10.1055/s-0040-1722722The introduction of thrombolytic therapy in the 1990s has transformed acute ischemic stroke treatment. Thus far, intravenous recombinant tissue plasminogen activator (rt-PA) also known as alteplase is the only thrombolytic proven to be efficacious and approved by the United States Food and Drug Administration. But the thrombolytic agent tenecteplase (TNK) is emerging as a potential replacement for rt-PA. TNK has greater fibrin specificity, slower clearance, and higher resistance to plasminogen activator inhibitor-1 than rt-PA. Hence, TNK has the potential to provide superior lysis wi...
Source: Seminars in Neurology - January 20, 2021 Category: Neurology Authors: Baird, Alison E. Jackson, Richard Jin, Weijun Tags: Review Article Source Type: research

Trends in ischemic stroke outcomes in a rural population in the United States
The stroke mortality rate has gradually declined due to improved interventions and controlled risk factors. We investigated the trends in stroke recurrence and all-cause mortality in stroke patients from a rural population in the United States between 2004 and 2018.
Source: Journal of the Neurological Sciences - February 8, 2021 Category: Neurology Authors: Durgesh Chaudhary, Ayesha Khan, Shima Shahjouei, Mudit Gupta, Clare Lambert, Venkatesh Avula, Clemens M. Schirmer, Neil Holland, Christoph J. Griessenauer, M. Reza Azarpazhooh, Jiang Li, Vida Abedi, Ramin Zand Source Type: research

Disparities in the Use of Mechanical Thrombectomy Alone Compared with Adjunctive Intravenous Thrombolysis in Acute Ischemic Stroke in the United States INTERVENTIONAL
CONCLUSIONS: Our results indicated that mechanical thrombectomy alone was used more frequently than MT+IV-tPA among patients with acute ischemic stroke. The disparity between those who identify as White and non-White persisted across the years, though it is closing.
Source: American Journal of Neuroradiology - December 13, 2021 Category: Radiology Authors: Wahood, W., Rizvi, A. A., Alexander, Y., Alvi, M. A., Rajjoub, K. R., Cloft, H., Rabinstein, A. A., Brinjikji, W. Tags: INTERVENTIONAL Source Type: research

E-123 Evaluation of safety and efficacy of transradial access for mechanical thrombectomy inacute ischemic stroke - A single center experience
ConclusionTransradial access for mechanical thrombectomy in acute ischemic stroke is a primary access in tortuous vasculature/posterior circulation strokes and is a good alternative to the femoral approach. This vascular access is especially helpful in patients with posterior circulation strokes, on anticoagulation or with large body habitus.Disclosures A. Kuhn: None. J. Singh: None. K. de Macedo Rodrigues: None. F. Massari: None. F. Massari: None. M. Gounis: 1; C; National Institutes of Health (NIH), the United States – Israel Binational Science Foundation, Anaconda, ApicBio, Axovant, Cerenovus, Cook Medical, Gentui...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Kuhn, A., Singh, J., de Macedo Rodrigues, K., Massari, F., Massari, F., Gounis, M., Puri, A. Tags: Electronic poster abstracts Source Type: research